Association between vitamin D deficiency and the risk factors for metabolic syndrome in postmenopausal women

Maturitas ◽  
2017 ◽  
Vol 100 ◽  
pp. 185-186
Author(s):  
Eneida Schmitt ◽  
Jorge Nahas-Neto ◽  
Flavia Bueloni-Dias ◽  
Priscila Poloni ◽  
Ana Laura Lucca ◽  
...  
2021 ◽  
Vol 03 (04) ◽  
pp. 70-77
Author(s):  
N.M. Inoyatova ◽  

In conditions of age-related decrease in sex hormones and a number of pathological conditions and diseases in postmenopausal women, there is a deficiency of D hormone. In our country, the geographic location of which is below northern latitude and sufficient ultraviolet radiation, an insufficient content of vitamin D is seen in postmenopausal women. There are a lot of risk factors leading to vitamin D deficiency - the presence of smog and dust in cities, insufficient consumption of vitamin-fortified foods, the presence of problems with the gastrointestinal tract and excretory system and a number of others. One of the important factors that reduce vitamin storage is overweight and obesity, especially in combination with old age, when all absorption processes are reduced. The aim of our research was to study risk factors in women with vitamin D deficiency with subsequent correction of the deficiency state. We examined the level of total 25 (OH) D in the blood serum in 46 postmenopausal women, and identified risk factors. Vitamin D deficiency was detected in 86.96% of women, and its deficiency was registered in 10.87%. At the same time, a pronounced vitamin deficiency was not registered in any patient. Overweight was registered in 32.6%, obesity of varying degrees in 26.1%. Given the indicators, recommendations were given for correcting vitamin D deficiency. All postmenopausal women, especially those with risk factors for deficiency, are recommended to determine the basic level of vitamin D. In case of deficiency, drug correction is recommended to reduce the risk of cardiovascular and oncological diseases.


Author(s):  
Nazila Fathi Maroufi ◽  
Pourya Pezeshgi ◽  
Zohreh Mortezania ◽  
Pirouz Pourmohammad ◽  
Reyhaneh Eftekhari ◽  
...  

AbstractBackgroundThe increasing prevalence of metabolic syndrome (MS) especially in female population, has become a major problem in health care systems. In this regards, it is necessary to identify the risk factors. Vitamin D deficiency is now proposed as one of the possible risk factors for metabolic syndrome, we investigated the relationship between vitamin D status and MS in female.MethodsWe searched observational studies with keywords Vitamin D, metabolic syndrome, metabolic syndrome X, insulin-resistance syndrome, metabolic cardiovascular syndrome and Reaven Syndrome X and female in pubmed, scopus, science direct, cochrane, web of science, google scholar and SID databases, regardless of publication time. Two hundred ninety five studies were found, and finally only 12 articles were selected according to exclusion and inclusion criteria.ResultsIn nine studies that reported the prevalence of MS, the prevalence of MS among women with vitamin D deficiency was higher than female with normal vitamin D (34.5 vs. 30.2%). The prevalence of abdominal obesity, high blood pressure, high TG and HDL deficiency is higher in women with vitamin D deficiency. Also, the mean waist circumference, blood pressure, fast blood sugar (FBS), TG and BMI were higher. The most incident factor was high blood pressure (61.4 vs. 56.5%) and the lowest prevalence is associated with high FBS (32.2 vs. 33.5% in the other group).ConclusionThe prevalence of MS is significantly associated with vitamin D deficiency, and among related factors, HDL, TG and blood pressure are statistically associated with vitamin D status.


Author(s):  
Lyudmila V. Vasilieva ◽  
◽  
Yuliya V. Tatarintseva ◽  
Elena V. Gosteva ◽  
Sergej Y. Popov ◽  
...  

Objective: To assess the relationship between vitamin D deficiency (VD) and risk factors for metabolic syndrome (MS) in postmenopausal women with arterial hypertension (AH). Materials and methods of research. The study included 46 women aged 45–65 years with amenorrhea > 12 months, having grade 1 hypertension and metabolic syndrome. Anthropometric, laboratory and instrumental data were studied. Biochemical parameters included total cholesterol (OH), HDL, triglycerides, glucose, insulin, and 25-hydroxyvitamin-D [25 (OH)D]. Daily blood pressure monitoring was performed according to the standard protocol. Levels of 25(OH)D in blood serum was classified as-adequate (≥ 30 ng/ml) and insufficient (20–29 ng/ml). Results: Level 25 (OH)D in blood serum was sufficient in 21 women (45.6 %), insufficient – in 25 (54.4 %). Women with insufficient levels of 25 (OH)D had higher levels of cholesterol, triglycerides, insulin, and HOMA-IR. Metabolic syndrome was detected in 64 % (16/25) of women with hypovitaminosis D and in 43 % (9/21) of women with sufficient VD (p < 0.01). The correlation analysis established the relationship of the low level of 25 (OH)D (< 30 ng / ml) with MS (r = 0.68), high triglycerides (r = 0.74) and low HDL (r = 0.71). The average concentration of 25 (OH) D decreased with an increase in the number of MS components (p = 0.016). Conclusions: VD deficiency in postmenopausal women was associated with a higher prevalence of MS. Women with HDL deficiency had a higher risk of MS, hypertriglyceridemia, and low HDL levels compared to those with adequate levels.


Maturitas ◽  
2018 ◽  
Vol 107 ◽  
pp. 97-102 ◽  
Author(s):  
Eneida Boteon Schmitt ◽  
Jorge Nahas-Neto ◽  
Flavia Bueloni-Dias ◽  
Priscila Ferreira Poloni ◽  
Claudio Lera Orsatti ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Luz Adriana Sarmiento-Rubiano ◽  
José Armando Angarita Ruidiaz ◽  
Héctor Fernando Suarez Dávila ◽  
Alfonso Suarez Rodríguez ◽  
Roberto C. Rebolledo-Cobos ◽  
...  

Background. Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels. For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD), mainly those related with metabolic syndrome.Objective. To assess the relationship between the serum vitamin D (25-OH-D) levels and the metabolic syndrome markers in postmenopausal women.Methods. This descriptive and cross-sectional study was conducted in 183 postmenopausal women of four municipalities from Colombian Caribbean. The serum 25-OH-D levels and the anthropometric and biochemical markers were assessed and correlated with metabolic syndrome.Results. The average value of serum vitamin D (25-OH-D) was 26.34 ± 9.08 ng/mL, and 69.95% of the women had vitamin D levels <30 ng/mL, of which 43.72% were with insufficiency (<30 to >20 ng/mL) and 26.23% with deficiency (<20 ng/mL). Of the evaluated women, the 81.42% seemed to have metabolic syndrome. Through the linear regression, one significant positive association was observed between the HDL cholesterol and the 25-OH-D levels (P=0.014).Conclusion. In the evaluated population in this study, vitamin D deficiency is related with low HDL cholesterol levels.


2020 ◽  
Vol 11 ◽  
pp. 204201882093129
Author(s):  
Faustino R. Pérez-López ◽  
Peter Chedraui ◽  
Stefan Pilz

The purpose of this review was to assess recent evidence regarding the effects of low vitamin D levels on some highly prevalent clinical conditions of postmenopausal women. We reviewed and selected recent literature regarding menopause-related conditions associated with vitamin D deficiency and interventions to manage them. Low circulating 25-hydroxyvitamin D (25(OH)D) levels related to menopause are linked to diet, lifestyle, changes in body composition, insulin sensitivity, and reduced physical activity. Vitamin D supplementation increases serum 25(OH)D levels while normalizing parathyroid hormone and bone markers, and in women with serum 25(OH)D levels below 10 ng/ml supplementation may improve bone mineral density. Low vitamin D status has been associated with the metabolic syndrome, high triglyceride levels, and low high-density lipoprotein cholesterol levels. When compared with placebo, vitamin D supplementation may lower the risk of the metabolic syndrome, hypertriglyceridemia, and hyperglycemia. There is an inverse relationship between fat mass and serum 25(OH)D levels and, therefore, the dosage of supplementation should be adjusted according to the body mass index. Although vitamin D supplementation may improve glucose metabolism in prediabetic subjects, data regarding muscle strength are conflictive. There is evidence that vitamin D over-treatment, to reach extremely high circulating 25(OH)D levels, does not result in better clinical outcomes. The identification and treatment of vitamin D deficiency in postmenopausal women may improve their general health and health outcomes. Vitamin D supplementation should preferably be based on the use of either cholecalciferol or calcifediol.


2018 ◽  
Author(s):  
Alena Andreeva ◽  
Olga Belyaeva ◽  
Anna Bystrova ◽  
Elena Bajenova ◽  
Tatiana Karonova

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