Abstract
Hydroxyapatite is a bioceramic material and it is one of the most important inorganic compounds which are extensively used in several forms as a bone substitute material. Hydroxyapatite is chemically represented as (Ca10(PO4)6(OH)2), and is chemically and crystallographically similar to the human hard tissue. The hydroxyapatite nanoparticle is mainly used in orthopaedic and dental applications due to its properties of bioactivity, osteoconduction, biocompatibility and non-toxicity. In this research work, poly vinyl alcohol assisted strontium substituted hydroxyapatite nano powders was synthesised by conventional hydrothermal coupled microemulsion method using dimethyl sulfoxide and hexane. It is well known that strontium stimulates bone formation, reduction bone resorption and it is also used to osteoporosis diseases, while poly vinyl alcohol (PVA) helps in controlling the morphology and it is beneficial for artificial bone formation and possess excellent bioactivities properties. The structure, chemical composition and morphology were investigated by different techniques such as XRD, FTIR, SEM and MTT assay. The results indicated that the poly vinyl alcohol assisted Sr substituted hydroxyapatite nanoparticle has a uniform spherical morphology, smaller particle size and with no impurities. The biomedical application studies of the as-synthesised material are yet to be studied.
Synthesis and characterization of dimethacrylates containing quaternary ammonium functionalities for dental applications