scholarly journals Associations between anxiety and depression symptoms and cognitive testing and neuroimaging in type 2 diabetes

2016 ◽  
Vol 30 (1) ◽  
pp. 143-149 ◽  
Author(s):  
Laura M. Raffield ◽  
Gretchen A. Brenes ◽  
Amanda J. Cox ◽  
Barry I. Freedman ◽  
Christina E. Hugenschmidt ◽  
...  
2020 ◽  
Author(s):  
Björg Ásbjörnsdóttir ◽  
Marianne Vestgaard ◽  
Nicoline C. Do ◽  
Lene Ringholm ◽  
Lise L.T. Andersen ◽  
...  

2011 ◽  
Vol 26 (S2) ◽  
pp. 1181-1181
Author(s):  
J. Masmoudi ◽  
L. Mnif ◽  
R. Damak ◽  
N. Charfi ◽  
H. Zouari ◽  
...  

ObjectiveThe objective of this work was to study the prevalence of anxiety and depression in a population of elderly diabetics and their impact on the glycemic control and the disease evolution.MethodsIt was a prospective, descriptive and analytical study on 62 elderly patients with type 2 diabetes. A structured questionnaire was used to collect socio-demographic data to describe the participants and aspects of their diabetes. Anxiety and depression symptoms were assessed with the Hospital Anxiety and Depression Scale (HADS).ResultsThe patients’ mean age was 66.82 years with a standard deviation of 4.8. The diabetes study population was predominantly female (74.2%). Average duration of diabetes was 12 years with a standard deviation of 8.11. Prevalence of anxiety and depression in diabetic elderly patients was respectively 40.3% and 22.6% with a female dominance. 67.7% of elderly diabetes had poor glycemic control. Comparing anxiety mean scores, patients with worse glycemic control had significantly higher scores (9 06 ± 3. 14 vs 6.55; p = 0. 017). We didn’t found a relationship between depression and glycemic control. In our population, the presence of complications were significantly associated with anxiety and depression.ConclusionSeveral studies have shown that the prevalence of anxiety and depression symptoms in elderly patients with diabetes is considerably higher than in general population samples. Depression represent a risk factor for morbidity specially in elderly subjects, which justify a detection of psychiatric symptoms in order to improve the quality of life and the evolution of the disease.


2013 ◽  
Vol 32 (1) ◽  
pp. 63-77
Author(s):  
Elisabete Gomes Costa ◽  
Ricardo Pereira Campos ◽  
Eleonora Cunha Costa

The aim ofthis study is to analyze the relationship between socio-demographic, clinicaland psychosocial variables in patients with Type 2 Diabetes and to establishcomparative patterns between genders with this disorder. Patientsfrom a primary care center were assessed through a researcher design form andthrough the Hospital Anxiety and Depression Scale, the Satisfaction with SocialSupport Scale and the Pittsburgh Sleep Quality Index. A total of90 patients with Type 2 Diabetes were enrolled in this study, with a mean ageof 56.67±6.41 years. The HADS depression presented a score of 3.77±2.98 and6.7% of the sample revealed depression symptoms. The HADS anxiety presentedscores of 7.27±5.07 and 36.6% of the subjects had anxiety symptoms. Regardingsocial support, the results were positive and similar between genders. When itcomes to sleep, the sample presented a PSQI of 8.68±2.87, with 73.3% ofpatients revealing poor sleep quality and 24.4% showing a sleep disorder. Whencomparing genders, females had higher scores of anxiety and depression andworse sleep quality. Inconclusion, we can state that anxiety symptoms are very prevalent in patientswith Type 2 Diabetes and women are more vulnerable to anxiety, depression symptomsand poor sleep quality.


Author(s):  
M. Graça Pereira ◽  
Susana Pedras ◽  
Gabriela Ferreira

AbstractAimThis study examined the differences and the predictive role of clinical variables, illness representations, anxiety, and depression symptoms, on self-reported foot care adherence, in patients recently diagnosed with type 2 diabetes mellitus (T2DM) and assessed no longer than a year after the diagnosis (T1) and four months later (T2).BackgroundThe high rate of diabetes worldwide is one of the major public health challenges. Foot care is the behavior least performed by patients although regular foot care could prevent complications such as diabetic foot and amputation. Psychosocial processes such as illness representations and distress symptoms may contribute to explain adherence to foot self-care behaviors.MethodsThis is a longitudinal study with two assessment moments. The sample included 271 patients, who answered the Revised Summary of Diabetes Self-Care Activities, Brief-Illness Perception Questionnaire, and Hospital Anxiety and Depression Scale.FindingsPatients reported better foot care adherence at T2. Having a higher duration of T2DM and the perception of more consequences of diabetes were associated with better self-reported foot care adherence, at T1. At T2, the predictors were lower levels of HbA1c, better self-reported foot care adherence at T1, higher comprehension about T2DM, as well as fewer depressive symptoms. Interventions to promote adherence to foot care should have in consideration these variables. The results of the present study may help health professionals in designing interventions that early detect depressive symptoms and address illness beliefs, in order to promote foot self-care behaviors reducing the incidence of future complications.


2021 ◽  
pp. 1-11
Author(s):  
Baizid Khoorshid Riaz ◽  
Shahjada Selim ◽  
Megan Neo ◽  
Md Nazmul Karim ◽  
M. Mostafa Zaman

<b><i>Methodology:</i></b> Biochemically confirmed type 2 diabetes mellitus (T2DM) patients (<i>n</i> = 1,114) were recruited from the outpatient department of 2 tertiary care hospitals in Dhaka, Bangladesh. Face-to-face interview was conducted using a semi-structured questionnaire containing sociodemographic parameters and relevant information about depression and diabetes. Biochemical test results and treatment-related information were taken from patients’ records. The Hospital Anxiety and Depression Scale (HADS) was used to screen all patients for psychiatric manifestation. Those diagnosed by HADS were subsequently reassessed using structured clinical interview for DSM-5 Disorders – Clinician Version. T2DM diagnosed at age &#x3c;40 years were considered as early onset T2DM. Association between age of onset category and depression was assessed using multivariable mixed-effect logistic regression adjusting for random variation of the area of residence and plausible confounders. <b><i>Results:</i></b> Around a third of the participants (32.5%) were diagnosed with T2DM before the age of 40 years. Early onset T2DM patients were found to have 57% increase in the risk of developing depression (OR 1.57; 95% CI 1.13–2.28; <i>p</i> = 0.011) in comparison to those with usual onset T2DM (≥40 years). Among other factors a positive family history for diabetes (OR 1.33; 95% CI 1.03–1.78; <i>p</i> = 0.038), poor glycemic control (OR 1.31; 95% CI 1.03–1.68; <i>p</i> = 0.028), presence of 1, or more diabetic complications (OR 1.37; 95% CI 1.03–1.78; <i>p</i> = 0.011) also showed increased risk of depression. <b><i>Conclusion:</i></b> Early onset T2DM patients are at greater risk of developing depression. The finding is likely to help in setting preventive strategies aiming to reduce the presence of concomitant depression symptoms among diabetes.


2014 ◽  
Vol 66 (2) ◽  
pp. 811-817
Author(s):  
Cristina Toarba ◽  
Simona Hogas ◽  
Adrian Covic ◽  
Manuela Padurariu ◽  
Alin Ciobica ◽  
...  

In the present report, we studied the associations that might exist between alcohol consumption, cognitive functions and diabetic pathology in patients with type 2 diabetes (T2D). The alcohol intake of 219 patients diagnosed with diabetes was classified into 6 groups: nondrinkers, 0.1-9.9, 10.0-14.9, 15.0-29.9, 30.0-49.9 and ? 50.0, according to the total amount (grams/day) of alcohol consumption. Our results mainly confirm that moderate alcohol consumption can reduce some of the neuropathological aspects of T2D, as demonstrated by the decrease in glycemic levels in patients that consumed higher levels of alcohol (30.0-49.9 g/day), when compared to non-drinkers (p=0.04) or groups in which individuals consumed 0.1-9.9 g/day (p=0.01) and 10.0-14.9 g/day (p=0.02). Regarding the results of cognitive testing, we noticed a significant increase in the values of the MMSE score a lower dose of alcohol intake (0.1-9.9 g/day) was compared with higher doses: 30.0-49.9 g/day (p=0.008) and ? 50.0 g/day (p=0.047).


Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3036
Author(s):  
Mengxiao Ren ◽  
Huaiyu Zhang ◽  
Jindan Qi ◽  
Anni Hu ◽  
Qing Jiang ◽  
...  

Background: Alow carbohydrate diet (LCD) is more beneficial for the glycometabolism in type 2 diabetes (T2DM) and may be effective in reducing depression. Almond, which is a common nut, has been shown to effectively improve hyperglycemia and depression symptoms. This study aimed to determine the effect of an almond-based LCD (a-LCD) on depression and glycometabolism, as well as gut microbiota and fasting glucagon-like peptide 1 (GLP-1) in patients with T2DM. Methods: This was a randomized controlled trial which compared an a-LCD with a low-fat diet (LFD). Forty-five participants with T2DM at a diabetes club and the Endocrine Division of the First and Second Affiliated Hospital of Soochow University between December 2018 to December 2019 completed each dietary intervention for 3 months, including 22 in the a-LCD group and 23 in the LFD group. The indicators for depression and biochemical indicators including glycosylated hemoglobin (HbA1c), gut microbiota, and GLP-1 concentration were assessed at the baseline and third month and compared between the two groups. Results: A-LCD significantly improved depression and HbA1c (p < 0.01). Meanwhile, a-LCD significantly increased the short chain fatty acid (SCFAs)-producing bacteria Roseburia, Ruminococcus and Eubacterium. The GLP-1 concentration in the a-LCD group was higher than that in the LFD group (p < 0.05). Conclusions: A-LCD could exert a beneficial effect on depression and glycometabolism in patients with T2DM. We speculate that the role of a-LCD in improving depression in patients with T2DM may be associated with it stimulating the growth of SCFAs-producing bacteria, increasing SCFAs production and GPR43 activation, and further maintaining GLP-1 secretion. In future studies, the SCFAs and GPR43 activation should be further examined.


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