Applying Early Intervention Strategies to Autoimmune Skin Diseases. Is the Window of Opportunity Preclinical? A Dermato-Rheumatology Perspective

Author(s):  
Lucy M. Carter ◽  
Dennis McGonagle ◽  
Edward M. Vital ◽  
Miriam Wittmann
Crisis ◽  
2015 ◽  
Vol 36 (6) ◽  
pp. 459-463
Author(s):  
Kate Monaghan ◽  
Martin Harris

Abstract. Background: Suicide is a pervasive and complex issue that can challenge counselors through the course of their careers. Research and practice focus heavily on crisis management and imminent risk rather than early intervention strategies. Early intervention strategies can assist counselors working with clients who have suicidal ideation, but are not at imminent risk, or with clients whose risk factors identify them as having a stronger trajectory for suicidal ideation. Aims: This systematic literature review examines the current literature on working with clients with suicidal ideation who are not at imminent risk, to ascertain the types of information and strategies available to counselors working with this client group. Method: An initial 622 articles were identified for analysis and from these 24 were included in the final review, which was synthesized using a narrative approach. Results: Results indicate that research into early intervention strategies is extremely limited. Conclusion: It was possible to describe emergent themes and practice guidelines to assist counselors working with clients with suicidal ideation but not at imminent risk.


2016 ◽  
Vol 22 (3) ◽  
pp. 176-185 ◽  
Author(s):  
Josephine Loftus ◽  
Bruno Etain ◽  
Jan Scott

SummaryWe offer a contemporary review of studies of the offspring of parents with bipolar disorder and explore the clinical characteristics of these populations. We discuss how different methodological approaches may influence study findings and may explain some of the heterogeneity in the results reported. We also highlight some of the environmental risk factors that may increase the likelihood of transition from an ‘at-risk’ or high-risk state to bipolar disorder. Last, we briefly discuss the implications of study findings for early intervention strategies and comment on such issues as genetic counselling and primary and early secondary prevention programmes.


PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e9421 ◽  
Author(s):  
Giovani L. Vasconcelos ◽  
Antônio M.S. Macêdo ◽  
Raydonal Ospina ◽  
Francisco A.G. Almeida ◽  
Gerson C. Duarte-Filho ◽  
...  

The main objective of the present article is twofold: first, to model the fatality curves of the COVID-19 disease, as represented by the cumulative number of deaths as a function of time; and second, to use the corresponding mathematical model to study the effectiveness of possible intervention strategies. We applied the Richards growth model (RGM) to the COVID-19 fatality curves from several countries, where we used the data from the Johns Hopkins University database up to May 8, 2020. Countries selected for analysis with the RGM were China, France, Germany, Iran, Italy, South Korea, and Spain. The RGM was shown to describe very well the fatality curves of China, which is in a late stage of the COVID-19 outbreak, as well as of the other above countries, which supposedly are in the middle or towards the end of the outbreak at the time of this writing. We also analysed the case of Brazil, which is in an initial sub-exponential growth regime, and so we used the generalised growth model which is more appropriate for such cases. An analytic formula for the efficiency of intervention strategies within the context of the RGM is derived. Our findings show that there is only a narrow window of opportunity, after the onset of the epidemic, during which effective countermeasures can be taken. We applied our intervention model to the COVID-19 fatality curve of Italy of the outbreak to illustrate the effect of several possible interventions.


2021 ◽  
Author(s):  
Bart Geerling ◽  
Saskia M. Kelders ◽  
Ralph W. Kupka ◽  
Anja W.W.M. Stevens ◽  
Ernst T. Bohlmeijer

Abstract Background The Life-Chart Method (LCM) is an effective self-management treatment option in bipolar disorder (BD). There is insufficient knowledge about the consumers' needs and desires for an e-monitoring solution. The first step towards a new mood monitoring application is an extended inventory among consumers and professionals.BackgroundThe aim of the current study was: to identify opinions about online mood monitoring of patients with BD and professionals and to identify preferences on design, technical features and options facilitating optimal use and implementation of online mood monitoring.This study used a qualitative design with focus groups. Participants were recruited among patients and care providers. Three focus groups were held with eight consumers and five professionals. ResultsThe focus group meetings reveal a shared consciousness of the importance of using the Life-Chart Method for online mood monitoring. There is a need for personalization, adjustability, a strict privacy concept, an adjustable graphic report, and a link to early intervention strategies in the design. Due to the fact that this is a qualitative study with a relative small number of participants, so it remains unclear whether the results are fully generalizable. We can’t rule out a selection bias.Conclusions This study demonstrates the importance of involving stakeholders in identifying a smartphone-based mood charting applications' requirements. Personalization, adjustability, privacy, an adjustable graphic report, and a direct link to early intervention strategies are necessary requirements for a successful design. The results of this value specification are included in the follow-up of this project.


2020 ◽  
Vol 63 (1) ◽  
Author(s):  
Jessica McClelland ◽  
Lauren Robinson ◽  
Rachel Potterton ◽  
Victoria Mountford ◽  
Ulrike Schmidt

Abstract Background. Eating disorders (EDs) are serious mental illnesses that can be life-threatening. Stage of illness models and early intervention strategies could be informed by a better understanding of symptomatology that precedes the onset of an ED. This review aims to explore which symptoms (both ED and other psychiatric disorder-related) exist prior to the onset of an ED and whether there any prospective associations between these symptomatologies. Methods. A systematic literature review was conducted in MEDLINE, Embase, and PsycINFO for large, longitudinal, prospective studies in nonclinical cohorts of children/adolescents that report symptoms prior to the onset of an ED. A quality assessment of included studies was conducted using the Newcastle-Ottawa Quality Assessment Scale. Results. A total of 22 studies were included, and over half were assessed to be of good quality. Studies identified the presence of a broad range of ED and other psychiatric disorder-related symptoms prior to ED onset. Possible prospective associations were identified, including early eating and feeding difficulties in childhood, to ED-related symptoms (e.g., dieting and body dissatisfaction) and other psychiatric disorder-related symptoms (e.g., anxiety and depression) in childhood/early adolescence, progressing to severe symptomatology (e.g., extreme weight control behaviors and self-harm) in mid-adolescence/emerging adulthood. Conclusion. The trajectory of symptoms identified to precede and possibly predict onset of an ED may inform early intervention strategies within the community. Suggestions for further research are provided to establish these findings and the clinical implications of these discussed, in order to inform how best to target prodromal stages of EDs.


1987 ◽  
Vol 5 (3-4) ◽  
pp. 109-118 ◽  
Author(s):  
Sue Crane

Feeding the handicapped child occurs three or four times per day, every day of the year, despite the child's feeding problems and, in the vast majority of cases, without life threatening consequences. Yet the need for adequate feeding therapy for these children is becoming increasingly recognised. This paper seeks to explore why intervention is so important. The complex causes of feeding problems will be reviewed briefly followed by a discussion of the reasons for intervention. Feeding therapy techniques, strategies and approaches will be reviewed with the need for parent involvement, early intervention and a ‘feeding-team’ being stressed throughout. This paper highlights the need for intervention in feeding problems, whether or not they are life threatening, particularly in view of their effect upon quality of life of both the child and his family.


1987 ◽  
Vol 6 (4) ◽  
pp. 325-339 ◽  
Author(s):  
Thomas F. Babor ◽  
Patricia Korner ◽  
Charles Wilber ◽  
Susan Possidente Good

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