Effect of gender and sex factors on MS course in women

2019 ◽  
Vol 405 ◽  
pp. 326
Author(s):  
M. Missaoui ◽  
S. Naija ◽  
A. Hassine ◽  
M. Ben Halima ◽  
R. Douma ◽  
...  
Keyword(s):  
1933 ◽  
Vol 67 (712) ◽  
pp. 473-476 ◽  
Author(s):  
R. C. Punnett
Keyword(s):  

1980 ◽  
Vol 35 (2) ◽  
pp. 121-130 ◽  
Author(s):  
P. G. Rubini ◽  
M. Vecchi ◽  
M. G. Franco

SUMMARYIn the housefly, mosaics appear spontaneously but rarely. Sexual mosaics or gynandromorphs also appear in strains in which sex determination is based on autosomal sex factors. Rare cases of recombination in the male have been reported by some authors. In field and laboratory populations, mitotic plates with figures indicating exchange of chromatid segments are regularly observed in tissues of individuals of both sexes and at all stages of development. All these anomalies are interpreted as outward manifestation of the same phenomenon: mitotic recombination. The cytological basis of mitotic recombination, its relative frequency, its influence on linkage and genetic variability are discussed.


1973 ◽  
Vol 21 (3) ◽  
pp. 263-272 ◽  
Author(s):  
J. M. Pemberton ◽  
B. W. Holloway

SUMMARYOf 150 wild-type strains ofPseudomonas aeruginosaexamined, 48 formed recombinants when mated toP. aeruginosastrain PAO FP−and hence presumably possess sex factors. Three different types of sex factor were distinguished by the pattern of transfer of particular markers in different regions of the chromosome and by the ability to confer resistance to mercury in strain PAO. One new sex factor, FP39, was studied in detail, and while similar to the previously studied FP2 in terms of transfer kinetics, natural stability and resistance to curing by acridines, it differed from FP2 in promoting chromosome transfer from a site 10 min to the left of the FP2 origin and in showing apparently aberrant entry kinetics for a leucine marker situated 48 min from the FP2 origin. This was due to FP39 having a genetic determinant either for a structural gene of leucine biosynthesis or a specific suppressor gene for this locus. PAO strains carrying both FP2 and FP39 were unstable for both sex factors, suggesting a relationship between them.


Bothalia ◽  
1980 ◽  
Vol 13 (1/2) ◽  
pp. 161-169 ◽  
Author(s):  
D. Wiens ◽  
B. A. Barlow

Sex-associated and floating translocation complexes are characteristic of dioecious species of  Viscum,  but are virtually absent in monoecious species. The majority of dioecious species has fixed sex-associated translocation complexes with the male being the heterozygous sex. The sex-associated multivalent is usually O4 (ring-of-four) or O6 , rarely O8 . Dioecious species without sex-associated translocations are much less common. Most of the dioecious species are also polymorphic for floating translocations, producing one or more additional multivalents ranging from O4 to O12. Floating translocations may be more frequent in species that do not have sex-associated translocations. Supernumerary chromosomes are also present in several species. Sex ratios are at unity in most dioecious species, but female-biased ratios may occur in some species. The high correlation between dioecy and translocation heterozygosity suggests that translocations are primarily associated with the origin and establishment of dioecy. Any róle in the maintenance of biased sex ratios through meiotic drive is probably secondary. Sex-associated translocations may serve to stabilize dioecy by bringing the sex factors into close linkage. Subsequent structural rearrangements within a sex-associated translocation complex may bring the sex factors together in one chromosome pair, releasing floating translocations. The high frequencies of floating translocation heterozygosity in some species indicate that such heterozygosity also has adaptive value.


2014 ◽  
Vol 29 (4) ◽  
pp. 522 ◽  
Author(s):  
Sunghwan Suh ◽  
Jongha Baek ◽  
Ji Cheol Bae ◽  
Kyoung-Nyoun Kim ◽  
Mi Kyoung Park ◽  
...  

2017 ◽  
Vol 14 (6) ◽  
pp. e358
Author(s):  
S.C. Van Vleet ◽  
J.L. Warmann ◽  
I.V. Maciel ◽  
V.P. Germán ◽  
M.A. King ◽  
...  

1913 ◽  
Vol 3 (2) ◽  
pp. 121-122
Author(s):  
J. A. Jenkins
Keyword(s):  

1975 ◽  
Vol 37 (1) ◽  
pp. 103-106 ◽  
Author(s):  
Larry J. Coet ◽  
Larry W. Thornton

A random sample of 67 males and 74 females was divided into three age groups: 12 to 25, 26 to 45, and 46 to 82 yr. old. Subjects were given a questionnaire asking them to rank five groups or classes of people they felt should be labeled “handicapped.” An analysis of variance indicated that over-all, definitions of the term “handicap” differed significantly according to age and sex. Males emphasized “social” and “intellectual” conditions, while females stressed the more visible (unattractive) conditions. The youngest age group listed “race,” “speech,” and “socio-economic” conditions more frequently, while the middle-aged group was more concerned with “physical incapacitation,” “blindness,” and “heart disease.” The oldest age group stressed “mental illness” and “mental retardation” most frequently.


1974 ◽  
Vol 23 (3) ◽  
pp. 327-334 ◽  
Author(s):  
V. Krishnapillai

SUMMARYSix bacteriophages have been used in the classification of 19 plasmids (antibiotic resistance-mediating R factors and FP sex factors which promote host chromosome transfer) ofP. aeruginosaisolated in different geographical regions. On the basis of phage-plating responses on isogenic strains of bacteria differing only in the plasmids carried, five groups of plasmids were distinguishable. In general the groups could be correlated with their geographical origin although differences between plasmids from the same region were found. The unique phage-plating responses were also useful in establishing the possible identity of plasmids isolated from the same original strain and given different designations by independent investigators. The classification of the plasmids derived here on the basis of phage-plating responses could be correlated with classifications based upon other phenotypic characteristics described elsewhere. The nature of inhibition of plating of phages B39 and G101 by R18–1 and R18–3 respectively was shown to be due to interference with some aspect of intra-cellular phage replication rather than to plasmid-mediated restriction.


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