Identifying socioeconomic, psychiatric, and biological risk factors in psychogenic non-epileptic seizures

2021 ◽  
Vol 429 ◽  
pp. 119745
Author(s):  
Rachel Gorenflo ◽  
Richard Ho ◽  
Enrique Carrazana ◽  
Jason Viereck ◽  
Kore Liow ◽  
...  
Keyword(s):  
Risk Factors ◽  
Epileptic Seizures ◽  
Biological Risk

scholarly journals Changes in lifestyle, biological risk factors and total homocysteine in relation to MTHFR C677T genotype: a 5-year follow-up study

2009 ◽  
Vol 63 (10) ◽  
pp. 1233-1240 ◽  
Author(s):  
L L N Husemoen ◽  
A Linneberg ◽  
M Fenger ◽  
B H Thuesen ◽  
T Jørgensen
Keyword(s):  
Risk Factors ◽  
Mthfr C677t ◽  
Biological Risk ◽  
Follow Up Study ◽  
Total Homocysteine ◽  
Genotype A

Complications Following Decompressive Craniectomy

2021 ◽  
Author(s):  
Jan Mraček ◽  
Jan Mork ◽  
Jiri Dostal ◽  
Radek Tupy ◽  
Jolana Mrackova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Decompressive Craniectomy ◽  
Clinical Status ◽  
Fluid Collection ◽  
Epileptic Seizures ◽  
Middle Cerebral Artery Infarction ◽  
Temporal Muscle ◽  
Life Saving ◽  
Potential Risk Factors ◽  
The Impact

Abstract Background Decompressive craniectomy (DC) has become the definitive surgical procedure to manage a medically intractable rise in intracranial pressure. DC is a life-saving procedure resulting in lower mortality but also higher rates of severe disability. Although technically straightforward, DC is accompanied by many complications. It has been reported that complications are associated with worse outcome. We reviewed a series of patients who underwent DC at our department to establish the incidence and types of complications. Methods We retrospectively evaluated the incidence of complications after DC performed in 135 patients during the time period from January 2013 to December 2018. Postoperative complications were evaluated using clinical status and CT during 6 months of follow-up. In addition, the impact of potential risk factors on the incidence of complications and the impact of complications on outcome were assessed. Results DC was performed in 135 patients, 93 of these for trauma, 22 for subarachnoid hemorrhage, 13 for malignant middle cerebral artery infarction, and 7 for intracerebral hemorrhage. Primary DC was performed in 120 patients and secondary DC in 15 patients. At least 1 complication occurred in each of 100 patients (74%), of which 22 patients (22%) were treated surgically. The following complications were found: edema or hematoma of the temporal muscle (34 times), extracerebral hematoma (33 times), extra-axial fluid collection (31 times), hemorrhagic progression of contusions (19 times), hydrocephalus (12 times), intraoperative malignant brain edema (10 times), temporal muscle atrophy (7 times), significant intraoperative blood loss (6 times), epileptic seizures (5 times), and skin necrosis (4 times). Trauma (p = 0.0006), coagulopathy (p = 0.0099), and primary DC (p = 0.0252) were identified as risk factors for complications. There was no significant impact of complications on outcome. Conclusions The incidence of complications following DC is high. However, we did not confirm a significant impact of complications on outcome. We emphasize that some phenomena are so frequent that they can be considered a consequence of primary injury or natural sequelae of the DC rather than its direct complication.

scholarly journals Postoperative Pneumocephalus on Computed Tomography Might Predict Post-Corpus Callosotomy Chemical Meningitis

2021 ◽  
Vol 11 (5) ◽  
pp. 638
Author(s):  
Ayataka Fujimoto ◽  
Keisuke Hatano ◽  
Toshiki Nozaki ◽  
Keishiro Sato ◽  
Hideo Enoki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Computed Tomography ◽  
Risk Factor ◽  
Intractable Epilepsy ◽  
Epileptic Seizures ◽  
Computed Tomography Scan ◽  
Corpus Callosotomy ◽  
Significant Difference ◽  
Chemical Meningitis ◽  
Tomography Scan

Background: A corpus callosotomy (CC) is a procedure in which the corpus callosum, the largest collection of commissural fibers in the brain, is disconnected to treat epileptic seizures. The occurrence of chemical meningitis has been reported in association with this procedure. We hypothesized that intraventricular pneumocephalus after CC surgery represents a risk factor for postoperative chemical meningitis. The purpose of this study was to analyze the potential risk factors for postoperative chemical meningitis in patients with medically intractable epilepsy who underwent a CC. Methods: Among the patients who underwent an anterior/total CC for medically intractable epilepsy between January 2009 and March 2021, participants were comprised of those who underwent a computed tomography scan on postoperative day 0. We statistically compared the groups with (c-Group) or without chemical meningitis (nc-Group) to determine the risk factors. Results: Of the 80 patients who underwent a CC, 65 patients (25 females and 40 males) met the inclusion criteria. Their age at the time of their CC procedure was 0–57 years. The c-Group (17%) was comprised of seven females and four males (age at the time of their CC procedure, 1–43 years), and the nc-Group (83%) was comprised of 18 females and 36 males (age at the time of their CC procedure, 0–57 years). Mann–Whitney U-tests (p = 0.002) and univariate logistic regression analysis (p = 0.001) showed a significant difference in pneumocephalus between the groups. Conclusion: Postoperative pneumocephalus identified on a computed tomography scan is a risk factor for post-CC chemical meningitis.

Acute symptomatic epileptic seizures in the early postoperative period

2021 ◽  
pp. 311-320
Author(s):  
Margarita Andreevna Fedorchenko ◽  
Pavel Shnyakin ◽  
Natalia Viktorovna Isayeva ◽  
Evgeny Aleksandrovich Yermilov
Keyword(s):  
Risk Factors ◽  
Postoperative Period ◽  
Epileptic Seizures ◽  
Early Postoperative Period ◽  
Diagnosis And Treatment ◽  
Initial Condition

The article provides an overview of recent studies related to epidemiology, diagnosis and treatment of acute symptomatic epileptic seizures (ASES)in the early postoperative period after brain intervention. Themain points distinguishing ASES fromseizures in epilepsy are highlighted. The initial condition of the patient, the reason for which the surgery was performed and the volume of the intervention are the main criteria that must be taken into account when assessing risk factors for epileptic seizures. An algorithm for managing a patient with ASES is presented.

541-P: Social and Biological Risk Factors Threaten Hispanics/Latinos with Type 2 Diabetes, Now at Risk for COVID-19

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 541-P
Author(s):  
NAMINO M. GLANTZ ◽  
ROSIRENE PACZKOWSKI ◽  
ARIANNA J. LAREZ ◽  
FELICIA GELSEY ◽  
BANRUO YANG ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
At Risk ◽  
Biological Risk

Trends in selected biological risk factors for cardiovascular diseases in the Danish MONICA population, 1982–1992

2000 ◽  
Vol 53 (4) ◽  
pp. 427-434 ◽  
Author(s):  
Lars Ulrik Gerdes ◽  
Henrik Brønnum-Hansen ◽  
Mette Madsen ◽  
Knut Borch-Johnsen ◽  
Torben Jørgensen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Diseases ◽  
Biological Risk

4. Trends in HIV Prevalence, Incidence and Demographic, Behavioral, and Biological Risk Factors Among Youth in Rakai, Uganda, 1999-2011

2013 ◽  
Vol 52 (2) ◽  
pp. S5 ◽  
Author(s):  
John S. Santelli ◽  
Zoe R. Edelstein ◽  
Ying Wei ◽  
Sanyukta Mathur ◽  
Fred Nalugoda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Prevalence ◽  
Biological Risk

Functional (psychogenic non-epileptic/dissociative) seizures: why and how?

2021 ◽  
pp. jnnp-2021-326708
Author(s):  
Deniz Ertan ◽  
Selma Aybek ◽  
W Curt LaFrance, Jr. ◽  
Kousuke Kanemoto ◽  
Alexis Tarrada ◽  
...  
Keyword(s):  
Risk Factors ◽  
Multilevel Models ◽  
Epileptic Seizures ◽  
Psychological Disorders ◽  
Narrative Review ◽  
Cognitive Risk ◽  
Underlying Mechanisms ◽  
Dissociative Seizures ◽  
Cognitive Risk Factors

Functional seizures (FS) known also as psychogenic non-epileptic seizures or dissociative seizures, present with ictal semiological manifestations, along with various comorbid neurological and psychological disorders. Terminology inconsistencies and discrepancies in nomenclatures of FS may reflect limitations in understanding the neuropsychiatric intricacies of this disorder. Psychological and neurobiological processes of FS are incompletely understood. Nevertheless, important advances have been made on underlying neuropsychopathophysiological mechanisms of FS. These advances provide valuable information about the underlying mechanisms of mind–body interactions. From this perspective, this narrative review summarises recent studies about aetiopathogenesis of FS at two levels: possible risk factors (why) and different aetiopathogenic models of FS (how). We divided possible risk factors for FS into three categories, namely neurobiological, psychological and cognitive risk factors. We also presented different models of FS based on psychological and neuroanatomical understanding, multilevel models and integrative understanding of FS. This work should help professionals to better understand current views on the multifactorial mechanisms involved in the development of FS. Shedding light on the different FS profiles in terms of aetiopathogenesis will help guide how best to direct therapy, based on these different underlying mechanisms.

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