Characterization of product-related low molecular weight impurities in therapeutic monoclonal antibodies using hydrophilic interaction chromatography coupled with mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2018.03.034 ◽

2018 ◽

Vol 154 ◽

pp. 468-475 ◽

Cited By ~ 16

Author(s):

Shunhai Wang ◽

Anita P. Liu ◽

Yuetian Yan ◽

Thomas J. Daly ◽

Ning Li

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Monoclonal Antibodies ◽

Hydrophilic Interaction Chromatography ◽

Low Molecular Weight ◽

Hydrophilic Interaction ◽

Therapeutic Monoclonal Antibodies

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Post-Column Denaturation-Assisted Native Size-Exclusion Chromatography–Mass Spectrometry for Rapid and In-Depth Characterization of High Molecular Weight Variants in Therapeutic Monoclonal Antibodies

Journal of the American Society for Mass Spectrometry ◽

10.1021/jasms.1c00289 ◽

2021 ◽

Author(s):

Yuetian Yan ◽

Tao Xing ◽

Anita P. Liu ◽

Zhengqi Zhang ◽

Shunhai Wang ◽

...

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Monoclonal Antibodies ◽

High Molecular Weight ◽

Size Exclusion Chromatography ◽

Size Exclusion ◽

Chromatography Mass Spectrometry ◽

Exclusion Chromatography ◽

Therapeutic Monoclonal Antibodies

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Development of hydrophilic interaction chromatography with quadruple time-of-flight mass spectrometry for heparin and low molecular weight heparin disaccharide analysis

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.7437 ◽

2015 ◽

Vol 30 (2) ◽

pp. 277-284 ◽

Cited By ~ 13

Author(s):

Yilan Ouyang ◽

Chengling Wu ◽

Xue Sun ◽

Jianfen Liu ◽

Robert J. Linhardt ◽

...

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Low Molecular Weight Heparin ◽

Time Of Flight ◽

Hydrophilic Interaction Chromatography ◽

Low Molecular Weight ◽

Hydrophilic Interaction ◽

Flight Mass Spectrometry

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Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis

Analytical Chemistry ◽

10.1021/acs.analchem.6b04726 ◽

2017 ◽

Vol 89 (3) ◽

pp. 2086-2092 ◽

Cited By ~ 49

Author(s):

Valentina D’Atri ◽

Szabolcs Fekete ◽

Alain Beck ◽

Matthew Lauber ◽

Davy Guillarme

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Analytical Tool ◽

Hydrophilic Interaction Chromatography ◽

Hydrophilic Interaction ◽

Powerful Analytical Tool ◽

Therapeutic Monoclonal Antibodies ◽

Level Of Analysis

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Further Characterization of Monoclonal Antibodies against Rat Plasma Kallikrein, Rat Low Molecular Weight Kininogen and Synthetic Bradykinin

Advances in Experimental Medicine and Biology - Kinins V ◽

10.1007/978-1-4615-9546-5_37 ◽

1989 ◽

pp. 223-230 ◽

Cited By ~ 1

Author(s):

Gurrinder S. Bedi ◽

Nathan Back

Keyword(s):

Molecular Weight ◽

Monoclonal Antibodies ◽

Rat Plasma ◽

Low Molecular Weight ◽

Plasma Kallikrein

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Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry

Analytical Chemistry ◽

10.1021/acs.analchem.8b03584 ◽

2018 ◽

Vol 91 (1) ◽

pp. 873-880 ◽

Cited By ~ 14

Author(s):

Valentina D’Atri ◽

Lucie Nováková ◽

Szabolcs Fekete ◽

Dwight Stoll ◽

Matthew Lauber ◽

...

Keyword(s):

Mass Spectrometry ◽

High Resolution ◽

High Resolution Mass Spectrometry ◽

Hydrophilic Interaction Chromatography ◽

Hydrophilic Interaction ◽

High Resolution Mass ◽

Glycan Heterogeneity ◽

Resolution Mass

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Hyphenation of strong cation exchange chromatography to native mass spectrometry for high throughput online characterization of charge heterogeneity of therapeutic monoclonal antibodies

mAbs ◽

10.1080/19420862.2020.1763762 ◽

2020 ◽

Vol 12 (1) ◽

pp. 1763762

Author(s):

Fengfei Ma ◽

Fahimeh Raoufi ◽

Marc Andre Bailly ◽

Laurence Fayadat-Dilman ◽

Daniela Tomazela

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Native Mass Spectrometry ◽

Exchange Chromatography ◽

Cation Exchange Chromatography ◽

Charge Heterogeneity ◽

Strong Cation Exchange ◽

Strong Cation Exchange Chromatography ◽

Therapeutic Monoclonal Antibodies

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Glycan profiling of monoclonal antibodies using zwitterionic-type hydrophilic interaction chromatography coupled with electrospray ionization mass spectrometry detection

Analytical Biochemistry ◽

10.1016/j.ab.2010.09.035 ◽

2011 ◽

Vol 408 (2) ◽

pp. 235-241 ◽

Cited By ~ 36

Author(s):

Lea Mauko ◽

Anna Nordborg ◽

Joseph P. Hutchinson ◽

Nathan A. Lacher ◽

Emily F. Hilder ◽

...

Keyword(s):

Mass Spectrometry ◽

Monoclonal Antibodies ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

Hydrophilic Interaction Chromatography ◽

Ionization Mass Spectrometry ◽

Ionization Mass ◽

Mass Spectrometry Detection ◽

Hydrophilic Interaction ◽

Glycan Profiling

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Characterization of low-molecular weight peptides in champagne wine by liquid chromatography/tandem mass spectrometry

Analytica Chimica Acta ◽

10.1016/j.aca.2004.03.094 ◽

2004 ◽

Vol 520 (1-2) ◽

pp. 149-158 ◽

Cited By ~ 19

Author(s):

Marine de Person ◽

Aude Sevestre ◽

P. Chaimbault ◽

Laurent Perrot ◽

Francis Duchiron ◽

...

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Low Molecular Weight ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Characterization of low molecular weight dissolved natural organic matter along the treatment trait of a waterworks using Fourier transform ion cyclotron resonance mass spectrometry

Water Research ◽

10.1016/j.watres.2012.07.004 ◽

2012 ◽

Vol 46 (16) ◽

pp. 5197-5204 ◽

Cited By ~ 76

Author(s):

Haifeng Zhang ◽

Yahe Zhang ◽

Quan Shi ◽

Shuoyi Ren ◽

Jianwei Yu ◽

...

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Organic Matter ◽

Fourier Transform ◽

Natural Organic Matter ◽

Cyclotron Resonance ◽

Low Molecular Weight ◽

Ion Cyclotron Resonance ◽

Ion Cyclotron

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Characterization of low molecular weight dissolved organic nitrogen by liquid chromatography-electrospray ionization-mass spectrometry

Limnology and Oceanography Methods ◽

10.4319/lom.2009.7.52 ◽

2009 ◽

Vol 7 (1) ◽

pp. 52-63 ◽

Cited By ~ 6

Author(s):

Philippa K. Curtis-Jackson ◽

Guillaume Massé ◽

Martha Gledhill ◽

Mark F. Fitzsimons

Keyword(s):

Mass Spectrometry ◽

Molecular Weight ◽

Liquid Chromatography ◽

Electrospray Ionization ◽

Electrospray Ionization Mass Spectrometry ◽

Dissolved Organic Nitrogen ◽

Organic Nitrogen ◽

Low Molecular Weight ◽

Ionization Mass

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