Green synthesis of silver nanoparticles from Curcuma longa L. and coating on the cotton fabrics for antimicrobial applications and wound healing activity

Author(s):  
M. Maghimaa ◽  
Sulaiman Ali Alharbi
Author(s):  
ANNAMALAI P ◽  
BALASHANMUGAM P ◽  
KALAICHELVAN PT

Objective: The present study was aimed to study at investigating the antibacterial potential of silver nanoparticles (AgNPs) coated cotton fabrics against different pathogens and also for their wound healing property using fibroblasts cells. Materials and Methods: The leaf extracts of Peltophorum pterocarpum were used for the synthesis of AgNPs and were characterizing using ultraviolet-visible spectrophotometer, transmission electron microscopy, energy dispersive X-ray (EDX) spectroscopy, dynamic light scattering analysis, and zeta potential measurement. The AgNPs were coated on cotton fabrics and tested for their antibacterial efficacy using agar well diffusion method. The wound healing property of synthesized AgNPs was tested using fibroblast 3T3 cells. Results: The plant extracts of P. pterocarpum were utilized for AgNPs. The optimum condition for synthesizing AgNPs was found to be 1 mg/ml plant concentration, 7 pH, 1 mM silver nitrate concatenation, and incubation temperature of 37°C. The shape of synthesized AgNPs was found to be spherical with an average size between 20 and 50 nm, and elemental silver peaks were confirmed by EDX spectrum. The cotton fabrics coated with AgNPs show good zone of inhibition against all the tested pathogens and the treated fabrics were also characterized using scanning electron microscope which reveals the presence of AgNPs on the fabrics. The scratch assay reveals that the AgNPs have good wound healing activity when tested against fibroblast 3T3. Conclusion: The present results conclude that the synthesized AgNPs have good stability with potent antimicrobial activity when coated with cotton fabrics. The AgNPs also found to have good activity significant wound healing activity when tested using fibroblast cells.


2017 ◽  
Vol 100 ◽  
pp. 187-196 ◽  
Author(s):  
Balashanmugam Pannerselvam ◽  
Mukesh Kumar Dharmalingam Jothinathan ◽  
Murugan Rajenderan ◽  
Palani Perumal ◽  
Kalaichelvan Pudupalayam Thangavelu ◽  
...  

RSC Advances ◽  
2017 ◽  
Vol 7 (68) ◽  
pp. 42900-42908 ◽  
Author(s):  
Gulzar Muhammad ◽  
Muhammad Ajaz Hussain ◽  
Muhammad Amin ◽  
Syed Zajif Hussain ◽  
Irshad Hussain ◽  
...  

Hydrogel forming polysaccharides are attracting attention for the design of diverse nature silver nanoparticles (Ag NPs) with potential biological applications.


Processes ◽  
2020 ◽  
Vol 8 (8) ◽  
pp. 998
Author(s):  
Kartini Kartini ◽  
Amarisa Alviani ◽  
Dia Anjarwati ◽  
Adinda Finna Fanany ◽  
Johan Sukweenadhi ◽  
...  

Silver nanoparticles (AgNPs) are an interesting metal nanoparticle that can be incorporated into pharmaceutical products, including for diabetic foot ulcers as an antimicrobial agent. Green synthesis of AgNPs using plant extracts has been drawing much attention as it is simple, eco-friendly, stable, and cost-effective. This present study was performed to evaluate the potential of three Indonesian medicinal plant extracts, namely Phyllanthus niruri (PN), Orthosiphon stamineus (OS), and Curcuma longa (CL), as reducing and capping agents in the green synthesis of AgNPs, and to optimize their concentrations. Based on the yields and characteristics of the formed nanoparticles, which were analyzed using a UV-Vis spectrophotometer, particle size analyzer, scanning electron microscope, and X-ray diffractometer, Phyllanthus niruri extract at a concentration of 0.5% was concluded as the best extract in the green synthesis of AgNPs. It is thereby a prospective reducing and capping agent for further scale-up studies.


RSC Advances ◽  
2019 ◽  
Vol 9 (67) ◽  
pp. 39434-39434
Author(s):  
Chunyi Tong ◽  
Wei Zou ◽  
Weimin Ning ◽  
Jialong Fan ◽  
Li Li ◽  
...  

Correction for ‘Synthesis of DNA-guided silver nanoparticles on a graphene oxide surface: enhancing the antibacterial effect and the wound healing activity’ by Chunyi Tong et al., RSC Adv., 2018, 8, 28238–28248.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Perumal Venkatachalam ◽  
Palanivel Sangeetha ◽  
Natesan Geetha ◽  
Shivendra Vikram Sahi

The present study describes a rapid method for synthesis of metallic silver nanoparticles using callus (CAgNPs) and leaf extracts (LEAgNPs) ofCucumis sativusand evaluation of its wound healing activity in rat model. The prepared silver nanoparticles showed a peak at 350 nm corresponding to the surface plasmon resonance band. The FTIR spectroscopy measurements showed the presence of the possible biomolecules. X-ray diffraction analysis confirmed the crystalline structure of the synthesized silver nanoparticles. TEM images showed the size of the synthesized CAgNPs with diameter ranged from 21 nm to 23 nm with polygonal shape whereas, in the case of LEAgNPs, spherical shape was noticed with an average size between 11 nm and 19 nm. The EDX results indicated the chemical composition at specific locations on synthesized nanoparticles. Furthermore the topical application of ointment prepared using synthesized AgNPs was found to show enhanced wound healing activity in Wistar albino rat model. By the 21st day, the ointment base containing 5% (w/w) of silver nanoparticles showed 100% potential wound healing activity than the standard drug as well as control bases. Results strongly showed that the ointment base containing LEAgNPs was found to be very effective in wound repair mechanism in the experimental rats.


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