57Fe Mössbauer spectroscopic analysis of deep-sea pelagic chert: Effect of secondary alteration with respect to paleo-redox evaluation

2011 ◽  
Vol 42 (6) ◽  
pp. 1403-1410 ◽  
Author(s):  
Tomohiko Sato ◽  
Yukio Isozaki ◽  
Katsumi Shozugawa ◽  
Motoyuki Matsuo
Keyword(s):  
Deep Sea ◽  
Spectroscopic Analysis ◽  
Secondary Alteration ◽  
57Fe Mössbauer

scholarly journals Dechdigliotoxins A–C, Three Novel Disulfide-Bridged Gliotoxin Dimers from Deep-Sea Sediment Derived Fungus Dichotomomyces cejpii

Marine Drugs ◽  
2019 ◽  
Vol 17 (11) ◽  
pp. 596 ◽  
Author(s):  
Zhaoming Liu ◽  
Zhen Fan ◽  
Zhanghua Sun ◽  
Hongxin Liu ◽  
Weimin Zhang
Keyword(s):  
Tumor Cell ◽  
Quantum Chemical Calculations ◽  
Cell Lines ◽  
Deep Sea ◽  
Quantum Chemical ◽  
Biosynthetic Pathway ◽  
Spectroscopic Analysis ◽  
Tumor Cell Lines ◽  
Disulfide Linkage ◽  
Deep Sea Sediment

Dechdigliotoxins A–C (1–3), which represented the first examples of gliotoxin dimers with an unprecedented exocyclic disulfide linkage, were obtained from a deep-sea derived fungus Dichotomomyces cejpii FS110. The structures of these compounds were elucidated on the basis of spectroscopic analysis and the absolute configurations were unambiguously determined through quantum chemical calculations, as well as DP4+ probability simulations. The proposed biosynthetic pathway suggested 1–3 were generated from unusual L-Phe and D-Ser. All the isolates were evaluated for their cytotoxicity against four tumor cell lines.

scholarly journals Two New Piperazine-Triones from a Marine-Derived Streptomycetes sp. Strain SMS636

Marine Drugs ◽  
2019 ◽  
Vol 17 (3) ◽  
pp. 186 ◽  
Author(s):  
Xiuli Xu ◽  
Jiahui Han ◽  
Rui Lin ◽  
Steven Polyak ◽  
Fuhang Song
Keyword(s):  
Staphylococcus Aureus ◽  
Minimum Inhibitory Concentration ◽  
Secondary Metabolites ◽  
Deep Sea ◽  
Spectroscopic Analysis ◽  
Inhibitory Concentration ◽  
2D Nmr ◽  
Antibacterial Activities ◽  
Bacillus Calmette Guerin ◽  
Methicillin Resistant

Two new piperazine-triones lansai E and F (1, 2), together with four known secondary metabolites lansai D (3), 1-N-methyl-(E,Z)-albonoursin (4), imidazo[4,5-e]-1,2,4-triazine (5), and streptonigrin (6) were isolated from a deep-sea-derived Streptomycetes sp. strain SMS636. The structures of the isolated compounds were confirmed by comprehensive spectroscopic analysis, including HRESIMS, 1D and 2D NMR. Compound 4 exhibited moderate antibacterial activities against Staphylococcus aureus and methicillin resistant S. aureus (MRSA) with Minimum Inhibitory Concentration (MIC) values of 12.5 and 25 μg/mL, respectively. Compound 6 displayed significant antibacterial activities against S. aureus, MRSA and Bacillus Calmette-Guérin (BCG) with MIC values of 0.78, 0.78 and 1.25 μg/mL, respectively.

scholarly journals Thioester-Containing Benzoate Derivatives with α-Glucosidase Inhibitory Activity from the Deep-Sea-Derived Fungus Talaromyces indigoticus FS688

Marine Drugs ◽  
2021 ◽  
Vol 20 (1) ◽  
pp. 33
Author(s):  
Mingqiong Li ◽  
Saini Li ◽  
Jinhua Hu ◽  
Xiaoxia Gao ◽  
Yanlin Wang ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Deep Sea ◽  
Spectroscopic Analysis ◽  
X Ray Diffraction ◽  
Docking Analysis ◽  
X Ray ◽  
Structure Activity ◽  
Ic50 Value ◽  
Ic50 Values ◽  
Benzoate Derivatives

Eurothiocins C–H (1–6), six unusual thioester-containing benzoate derivatives, were isolated from the deep-sea-derived fungus Talaromyces indigoticus FS688 together with a known analogue eurothiocin A (7). Their structures were elucidated through spectroscopic analysis and the absolute configurations were determined by X-ray diffraction and ECD calculations. In addition, compound 1 exhibited significant inhibitory activity against α-glucosidase with an IC50 value of 5.4 μM, while compounds 4 and 5 showed moderate effects with IC50 values of 33.6 and 72.1 μM, respectively. A preliminary structure–activity relationship is discussed and a docking analysis was performed.

scholarly journals Bioactive Metabolites from the Deep-Sea-Derived Fungus Diaporthe longicolla FS429

Marine Drugs ◽  
2020 ◽  
Vol 18 (8) ◽  
pp. 381
Author(s):  
Zhaoming Liu ◽  
Yuchan Chen ◽  
Saini Li ◽  
Qinglin Wang ◽  
Caiyun Hu ◽  
...  
Keyword(s):  
Deep Sea ◽  
Spectroscopic Analysis ◽  
Methanol Extract ◽  
Tyrosine Phosphatase ◽  
Bioactive Metabolites ◽  
X Ray Diffraction ◽  
Antiproliferative Effects ◽  
X Ray ◽  
Ic50 Value ◽  
First Time

The chemical investigation of a methanol extract of the deep-sea-derived fungus Diaporthe longicolla FS429 led to the isolation of two novel diterpenoids longidiacids A and B (1 and 2), two new polyketides (3 and 4), two new cytochalasin analogues longichalasins A and B (6 and 8) and three known analogues 5, 7, 9. Their structures were elucidated through comprehensive spectroscopic analysis, while the absolute configurations were established by the comparison of the experimental and quantum chemical calculated ECD spectra. The structure of compound 7 was confirmed through X-ray diffraction for the first time. In the bioassays compound 8 exhibited antiproliferative effects against SF-268, with an IC50 value of 16.44 μM. Moreover, compounds 1 and 8 were detected to inhibit 35.4% and 53.5% of enzyme activity of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) at a concentration of 50 μM.

57Fe Mössbauer spectroscopic analysis of a welding wire's coating

1989 ◽  
Vol 45 (1-4) ◽  
pp. 351-358
Author(s):  
E. De Grave ◽  
R. M. Persoons ◽  
R. E. Vandenberghe ◽  
D. G. Chambaere
Keyword(s):  
Spectroscopic Analysis ◽  
57Fe Mössbauer

scholarly journals Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008

Marine Drugs ◽  
2018 ◽  
Vol 16 (11) ◽  
pp. 448 ◽  
Author(s):  
Xiao Liang ◽  
Zhong-Hui Huang ◽  
Xuan Ma ◽  
Shu-Hua Qi
Keyword(s):  
Antibacterial Activity ◽  
Quantum Chemical Calculations ◽  
Acid Derivative ◽  
Deep Sea ◽  
Quantum Chemical ◽  
Spectroscopic Analysis ◽  
Fungal Strain ◽  
Cytotoxic Activities ◽  
Tetramic Acid ◽  
Cladosporium Sphaerospermum

Seven new unstable tetramic acid derivatives, cladosporiumins I-O (1–7), together with the known analogue cladodionen (8) were isolated from the extract of the deep-sea-derived fungus Cladosporium sphaerospermum EIODSF 008. Their structures were elucidated by spectroscopic analysis, quantum chemical calculations and ECD spectra. Compound 4 was a Mg complex of tetramic acid derivative. In acidic solvent, 4 could change to 1 and 6, and 7 could change to 5. In addition, 1, 5 and 8 existed as two exchangeable isomers, respectively. The structures of cladosporiumins E-H were reassigned as their Na complexes. The antibacterial and cytotoxic activities of 1–8 were also evaluated. However, because of their instability, all of the isolated compounds did not show significant antibacterial activity as the preliminary EtOAc extracts of the fungal strain.

57Fe Mössbauer spectroscopic analysis of chlorite

1987 ◽  
Vol 15 (2) ◽  
pp. 173-180 ◽  
Author(s):  
E. De Grave ◽  
J. Vandenbruwaene ◽  
M. Van Bockstael
Keyword(s):  
Spectroscopic Analysis ◽  
57Fe Mössbauer

scholarly journals Novel Macrolactams from a Deep-Sea-Derived Streptomyces Species

Marine Drugs ◽  
2020 ◽  
Vol 19 (1) ◽  
pp. 13
Author(s):  
Pei Wang ◽  
Dongyang Wang ◽  
Rongxin Zhang ◽  
Yi Wang ◽  
Fandong Kong ◽  
...  
Keyword(s):  
Deep Sea ◽  
Spectroscopic Analysis ◽  
Fermentation Broth ◽  
Light Conditions ◽  
X Ray Diffraction ◽  
Chemical Methods ◽  
Streptomyces Species ◽  
Deep Sea Sediment ◽  
Streptomyces Sp ◽  
X Ray

Four polyene macrolactams including the previously reported niizalactam C (4), and three new ones, streptolactams A–C (1–3) with a 26-membered monocyclic, [4,6,20]-fused tricyclic and 11,23-oxygen bridged [14,16]-bicyclic skeletons, respectively, were isolated from the fermentation broth of the deep-sea sediment-derived Streptomyces sp. OUCMDZ-3159. Their structures were determined based on spectroscopic analysis, X-ray diffraction analysis, and chemical methods. The abiotic formation of compounds 2 and 4 from compound 1 were confirmed by a series of chemical reactions under heat and light conditions. Compounds 1 and 3 showed a selective antifungal activity against Candida albicans ATCC 10231.

scholarly journals Structure and Absolute Configuration of Phenanthro-perylene Quinone Pigments from the Deep-Sea Crinoid Hypalocrinus naresianus

Marine Drugs ◽  
2021 ◽  
Vol 19 (8) ◽  
pp. 445
Author(s):  
Sahithya Phani Babu Vemulapalli ◽  
Juan Carlos Fuentes-Monteverde ◽  
Niels Karschin ◽  
Tatsuo Oji ◽  
Christian Griesinger ◽  
...  
Keyword(s):  
Natural Products ◽  
Dft Calculations ◽  
Absolute Configuration ◽  
13C Nmr ◽  
Deep Sea ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Water Soluble ◽  
Spectroscopy Analysis ◽  
1H And 13C Nmr

Two new water-soluble phenanthroperylene quinones, gymnochrome H (2) and monosulfated gymnochrome A (3), as well as the known compounds gymnochrome A (4) and monosulfated gymnochrome D (5) were isolated from the deep-sea crinoid Hypalocrinus naresianus, which had been collected in the deep sea of Japan. The structures of the compounds were elucidated by spectroscopic analysis including HRMS, 1D 1H and 13C NMR, and 2D NMR. The absolute configuration was determined by ECD spectroscopy, analysis of J-couplings and ROE contacts, and DFT calculations. The configuration of the axial chirality of all isolated phenanthroperylene quinones (2–5) was determined to be (P). For gymnochrome H (2) and monosulfated gymnochrome A (3), a (2′S,2″R) configuration was determined, whereas for monosulfated gymnochrome D (5) a (2′R,2″R), configuration was determined. Acetylated quinones are unusual among natural products from an echinoderm and gymnochrome H (2) together with the recently reported gymnochrome G (1) represent the first isolated acetylated phenanthroperylene quinones.

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