Ficus natalensis extract alleviates Cadmium chloride-induced testicular disruptions in albino rats

2022 ◽  
pp. 126924
Author(s):  
Shaimaa E.A. Elish ◽  
Fatma A. Sanad ◽  
Mostafa H. Baky ◽  
Noha A.E. Yasin ◽  
Abeer Temraz ◽  
...  
Keyword(s):  
Cadmium Chloride ◽  
Albino Rats

scholarly journals carcinogenicity of cadmium chloride via intraoeritoneal injection in albino rats

2006 ◽  
Vol 3 (4) ◽  
pp. 702-707
Author(s):  
Baghdad Science Journal
Keyword(s):  
Connective Tissue ◽  
Lung Tissue ◽  
Cadmium Chloride ◽  
Albino Rats ◽  
Pulmonary Carcinoma

Observed visually prominent lumps on the surface of the lung or embedded in lung tissue and microscopically Register Anfaj thrombosis with pulmonary carcinoma that took shape food or with the composition of the vesicles papillomavirus lining cells cubic vertical or connective tissue and increase

Hepatoprotective Effects of Solanum nigrum Linn Fruits Against Cadmium Chloride Toxicity in Albino Rats

2014 ◽  
Vol 160 (3) ◽  
pp. 400-408 ◽  
Author(s):  
Emam A. Abdel-Rahim ◽  
Yasmin E. Abdel-Mobdy ◽  
Rhaam F. Ali ◽  
Hend A. Mahmoud
Keyword(s):  
Cadmium Chloride ◽  
Solanum Nigrum ◽  
Albino Rats ◽  
Chloride Toxicity ◽  
Hepatoprotective Effects

scholarly journals Influence of water pH in the hepato- and nephrotoxicity of chronic cadmium poisoning in Wistar rats

2021 ◽  
Vol 10 (9) ◽  
pp. e12210917753
Author(s):  
Daniel José Pimentel Bonfim ◽  
Fernanda Maria Garcia ◽  
Cecília Braga Laposy ◽  
Rogério Giuffrida ◽  
Gisele Alborghetti Nai ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Drinking Water ◽  
Cadmium Chloride ◽  
Albino Rats ◽  
Acidic Ph ◽  
Alkaline Ph ◽  
Hydropic Degeneration ◽  
Neutral Ph ◽  
Cadmium Poisoning ◽  
Water Ph

Introduction: Cadmium is a heavy metal found in the environment that is used industrially; however, it also causes hepato- and nephrotoxic effects. Objective: To evaluate the effect of drinking water pH on the hepato- and nephrotoxicity caused by chronic cadmium poisoning. Material and Methods: We used 90 adult, male Wistar albino rats divided into 6 groups (n = 15): GC5 received a solution of cadmium chloride in drinking water with an acidic pH (pH 5.0); GC7 received a solution of cadmium chloride (400 mg/L) in drinking water with a neutral pH (pH 7.0 water); GC8 received a solution of cadmium chloride in water with an alkaline pH (pH 8.0); GWC5 received drinking water with an acidic pH (pH 5.0); GWC7 received drinking water with a neutral pH (pH 7.0); GWC8 received drinking water with an alkaline pH (pH 8.0). The animals were euthanized 6 months after the start of the experiment. We performed tests for hepatic and renal function and conducted liver and renal histopathology. Results: Water with an acidic pH caused alterations in ALP, ALT and urea in animals exposed to cadmium (P<0.05). In the liver, the majority of animals from the GC7 (57.1%) and GC5 (53.3%) groups showed diffuse microvesicular steatosis, while other groups showed no steatosis (P>0.05). In the kidney, the majority of animals from the GC7 (78.6%) and GWC5 (71.4%) groups showed tubular hydropic degeneration; however, these data were only statistically different from the GWC7 group (P<0.05). Conclusion: Exposure to cadmium in water with an acidic pH led to higher elevations of serum ALP, AST and urea, suggesting that the pH of drinking water influences the hepato- and nephrotoxic effects of this heavy metal.

scholarly journals Camel's Milk Protects Against Cadmium Chloride Induced Toxicity in White Albino Rats

2009 ◽  
Vol 4 (3) ◽  
pp. 107-117 ◽  
Author(s):  
Fahaid Al-Hashem ◽  
Mohammad Dallak ◽  
Nabil Bashir ◽  
Mohammad Abbas ◽  
Riyadh Elessa ◽  
...  
Keyword(s):  
Cadmium Chloride ◽  
Albino Rats ◽  
Camel's Milk

scholarly journals Histological changes in pituitary-testes axis in rats exposed to cadmium chloride: Protective role of Eruca sativa seeds

2017 ◽  
Vol 41 (1) ◽  
pp. 76-85
Author(s):  
Baraa Najim Al-Okaily
Keyword(s):  
Pituitary Gland ◽  
Cadmium Chloride ◽  
Tap Water ◽  
Antioxidant Properties ◽  
Ethanolic Extract ◽  
Seminiferous Tubules ◽  
Control Group ◽  
Albino Rats ◽  
Interstitial Tissue ◽  
Eruca Sativa

     The present study was carried out to investigate the protective effect of Eruca sativa seeds against changes of pituitary and testes in cadmium treated rats. Forty adult male albino rats were used and divided into 4 equal groups and treated for 8 weeks as follow: The first group was given distilled water and used as a control group. The second group (G1) was administered tap water containing 30 ppm/ L of cadmium chloride. Animals in third group (G2) received tap water containing Cadmium chloride as in G1 plus 250 mg/Kg B.W ethanolic extract of Eruca sativa seeds, while rats in fourth group (G3) administered 250 mg/Kg B.W of ethanolic extract of Eruca sativa seeds only. After 8 weeks of experiment the animals were anesthetized, the pituitary and testes were excised for histological studies. Results showed that cadmium chloride intake caused severe alterations in the pituitary gland manifested by a marked  apoptotic  cells  of  pars distalis, accompanied with marked necrosis leading to left large multiple spaces in their parenchyma. Whereas testes revealed shrinkage, irregular arrangement of seminiferous tubules and increase intertubular spaces. A considerable changes was also found in the seminiferous tubules with loss most of their epithelial layer and filled with cellular debris, incomplete spermatogenesis, congested blood vessels and few Leydig's cells. Administration of Eruca sativa extract reduce the deleterious effects of cadmium chloride on pituitary gland as well as more or less complete spermatogenesis process with thickness of interstitial tissue in most of seminiferous tubules. It could be suggested that the antioxidant properties of Eruca sativa extract protects the deleterious histological damage induced by cadmium chloride in adult rats.

scholarly journals The effectiveness of the protective role of beetroot juice for the male reproductive system of albino rats against the toxicity of cadmium chloride

2019 ◽  
Vol 24 (1) ◽  
pp. 43
Author(s):  
Qasim Azeez Razooqi AL-Janabi ◽  
Rashid Khamees Shaban ◽  
Noor Ibrahem Hasan AL-Kraie
Keyword(s):  
Cadmium Chloride ◽  
Protective Role ◽  
Control Group ◽  
Albino Rats ◽  
Distilled Water ◽  
Beetroot Juice ◽  
Negative Effects ◽  
Fourth Group ◽  
Abnormal Sperm

This study was designed to evaluate the protective role of beetroot juice against the toxicity of cadmium chloride (CdCl2) in male albino rats. The study included 20 male albino rats ages ranged between (2-3 months) and weights ranged between (220-260g), which were randomly distributed into 4 groups, the first group that has been promised to control group was given distilled water, the second group was given beetroot juice 10 ml/kg b.w., group third was given at a dose of cadmium chloride 5 mg/kg  b.w. for 30 days, which promised an infected control, and the fourth group were treated beetroot juice 10 ml/kg b. w. with cadmium chloride. The results showed that the treatment of animals cadmium chloride led group to a significant decrease (P ≤ 0.05) in the hormonal serum, to negative effects on of the natural shape of the sperm and to negative effects cleared on histological in testes tissues compared with the control group, In general has dosage rats treatment cadmium chloride juice of beetroot, to the positive improvement for most of the values ​​of previous indicators has led to increase significantly, the concentration of the LH, FSH and Testosterone hormone , to an improvement in the natural shape of the sperm, decreased significantly in the form abnormal sperm, led to an improvement cleared tissue in these totals became approach with what has been observed in the control group.   http://dx.doi.org/10.25130/tjps.24.2019.007     

Effect of cadmium chloride on interleukin-2, lymphocyte and DNA in adult male albino rats

2012 ◽  
Vol 211 ◽  
pp. S140
Author(s):  
Kawther Elhady ◽  
Ayman Abdelhamid ◽  
Rania Elgawish
Keyword(s):  
Adult Male ◽  
Cadmium Chloride ◽  
Interleukin 2 ◽  
Albino Rats
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