Adherence To Treatment And Modifiable Risk Factors In Acute Coronary Syndrome (Acs) Patients Registered In The Pgrx Real World Datasets

Background and Objectives: Acute Coronary Syndrome (ACS) is one of the major causes for mortality and morbidity among the cardiovascular diseases in India. In this study the modifiable risk factors leading to ACS are considered and its prevalence in a Tertiary care hospital is studied. Materials and Methods: This is a prospective type of study conducted in a tertiary care hospital. A total of 100 patients diagnosed with ACS were taken in this study. Their data was taken, and results were formulated in excel data sheet. Results: Among the UA patients, 65% were found to be dyslipidaemic, 60% as obese, 45% as diabetics, 47.5% as hypertensive and 40% as smokers. Among the NSTEMI patients, 66.67% were found to be dyslipidaemic, 52.78% as hypertensive, 44.44% as smokers, 30.56% as diabetics and 27.78% as obese. Among the STEMI patients, 37.50% were found to be dyslipidemic, 25% as both diabetic and obese, 20.83% as hypertensive,12.5% as smokers. Hypertension, dyslipidemia, smoking and obesity showed significance. Conclusion: The prevalence of modifiable risk factors is a major concern for developing ACS and when they are modified there will be a great reduction in the incidence of ACS.

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Discrimination of stress (Takotsubo) cardiomyopathy from acute coronary syndrome with clinical risk factors and coronary evaluation in real-world clinical practice

International Journal of Cardiology ◽

10.1016/j.ijcard.2017.02.071 ◽

2017 ◽

Vol 235 ◽

pp. 154-161 ◽

Cited By ~ 8

Author(s):

So-Ryoung Lee ◽

Sang Eun Lee ◽

Tae-Min Rhee ◽

Jin Joo Park ◽

Hyunjai Cho ◽

...

Keyword(s):

Risk Factors ◽

Acute Coronary Syndrome ◽

Clinical Practice ◽

Takotsubo Cardiomyopathy ◽

Real World ◽

Clinical Risk Factors ◽

Coronary Syndrome ◽

Clinical Risk

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Risk for recurrent cardiovascular events and expected risk reduction with optimal treatment one year after an acute coronary syndrome

European Heart Journal ◽

10.1093/ehjci/ehaa946.2969 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

S Zafeiropoulos ◽

I.T Farmakis ◽

A Kartas ◽

A Arvanitaki ◽

A Pagiantza ◽

...

Keyword(s):

Risk Factors ◽

Acute Coronary Syndrome ◽

Risk Reduction ◽

Risk Score ◽

Residual Risk ◽

Stable Phase ◽

Modifiable Risk Factors ◽

Clinical Issue ◽

Coronary Syndrome ◽

One Year

Abstract Background According to the latest ESC Guidelines for chronic coronary syndromes (CCS), patients who suffered an acute coronary syndrome (ACS) pass to a chronic stable phase after one year. In these patients the estimated 10-year risk for recurrent cardiovascular (CV) events varies considerably. We estimated this risk and the expected risk reduction after optimal control. Methods We applied the SMART risk score in 211 patients one year after an ACS to estimate the 10-year risk for recurrent CV events (subsequent non-fatal myocardial infarction, non-fatal stroke, or cardiovascular death). We assessed the distribution of the estimated risk and the potential risk reduction that might be achieved with an optimal guideline-directed management of modifiable risk factors (systolic blood pressure, low-density lipoprotein cholesterol, smoking and body mass index). Results In our cohort, the median SMART score was 16% [interquartile range (IQR), 9.5–26]. If all modifiable risk factors met guideline-recommended targets, median SMART risk score would be 9.4% (IQR, 5.9–17.1), with 52% of the patients at a 10-year risk <10%, while 10% and 11% at 20–30% and >30% risk respectively. The total median reducible risk was 4.7% (IQR, 1.7–8.8). Conclusions The SMART score had a wide distribution among patients with CCS. Noteworthy, one out of five patients will remain at a >20% 10-year risk, even with optimal risk factors management, clearly underlining that residual risk is an unmet clinical issue, which demands individualized patient care. Baseline and total residual risk score Funding Acknowledgement Type of funding source: None

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Distribution of Risk Factors in Patients with Acute Coronary Syndrome – a Hospital Based Study

Journal of Nepal Medical Association ◽

10.31729/jnma.636 ◽

2003 ◽

Vol 42 (148) ◽

Author(s):

Man B KC ◽

S Rajbhandari ◽

D Sharma ◽

R Malla ◽

YR Limbu ◽

...

Keyword(s):

Risk Factors ◽

Coronary Artery Disease ◽

Acute Coronary Syndrome ◽

Coronary Artery ◽

Disease Risk ◽

Positive Family History ◽

Modifiable Risk Factors ◽

Coronary Syndrome ◽

Strong Trend ◽

Artery Disease

A total of 230 patients admitted in coronary care unit of Shahid Gangalal National Heart Centre in betweenNovember 2001 and October 2002 were studied. 157 (68.2%) were male, with mean age of 62.8±11.8 years.Majority of acute coronary syndrome (ACS) events were observed in males with advanced age (> 65 years).About 68% patients with ACS were smoker, the most common modifiable risk factor followed by hypertension,dyslipidaemia and diabetes. A strong trend towards development of coronary artery disease (CAD) wasfound in subjects with positive family history of CAD. Multiple risk factors (2 or more) were present in vastmajority of patients. Modifiable risk factors, with smoking at number one position are more common inacute coronary syndrome patients. Appropriate management of modifiable risk factors is advisable to reducethe incidence of coronary artery disease.Key Words: Coronary Artery Disease, Risk Factors.

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Gender Difference in Frequency of Conventional Risk Factors in Patients with Acute Coronary Syndrome Admitted in Manipal Teaching Hospital, Pokhara, Nepal

Nepal Journal of Medical Sciences ◽

10.3126/njms.v1i1.5794 ◽

1970 ◽

Vol 1 (1) ◽

pp. 31-34

Author(s):

M Parajuli ◽

A Maskey ◽

SC Kohli ◽

UK Shrestha

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Coronary Artery Disease ◽

Acute Coronary Syndrome ◽

Alcohol Use ◽

Modifiable Risk Factors ◽

Coronary Syndrome ◽

Excessive Alcohol ◽

Artery Disease ◽

Conventional Risk Factors

Background: Acute coronary syndrome (ACS) is the major manifestation of coronary artery disease (CAD), which is a major killer of mankind. The modifiable risk factors for CAD may have different impact on men and women, which may also differ in different population groups. Identification and control of conventional risk factors is expected to result in a decline in incidence of CAD similar to that seen in western industrialized countries. Method: A retrospective study of 232 consecutive patients admitted to Manipal Teaching Hospital, Pokhara between September 2009 to December 2010 by studying their hospital records for following conventional risk factors of CAD viz Body mass index, current cigarette smoking, hypertension, excessive alcohol use, diabetes mellitus and dyslipidemia. The results were analyzed by SPSS 16. Results: The important modifiable risk factors in order of descending frequency were high BMI, smoking, hypertension, excessive alcohol use, raised total cholesterol, raised triglyceride and diabetes mellitus. Smoking and excessive use of alcohol were seen in statistically significant higher percentage of cases in males. Our study further revealed that in females, unstable angina whereas in males ST elevation myocardial infarction (STEMI) was present in statistically significant higher number of cases. Conclusion: Our study showed a statistically significant higher incidence of smoking and excessive alcohol use as risk factors for ACS in males. It was also seen that in females unstable angina and in males STEMI was present in statistically significant higher number of cases. Keywords: Acute coronary syndrome; Coronary artery disease; gender difference; risk factor DOI: http://dx.doi.org/10.3126/njms.v1i1.5794 Nepal Journal of Medical Sciences. 2012; 1(1): 31-34

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Pattern and Prevalence of Dyslipidemia among Patients with Acute Coronary Syndrome Admitted in a Tertiary Level Hospital

Bangladesh Heart Journal ◽

10.3329/bhj.v34i1.41905 ◽

2019 ◽

Vol 34 (1) ◽

pp. 31-36

Author(s):

Dilshad Parvin ◽

Sunil Krishna Baul ◽

SM Rahat Hossain ◽

Swati Munshi ◽

Md Hadiuzzaman ◽

...

Keyword(s):

Risk Factors ◽

Acute Coronary Syndrome ◽

Lipid Profile ◽

Troponin I ◽

Serum Levels ◽

Modifiable Risk Factors ◽

Coronary Syndrome ◽

Control Subjects ◽

Significant Difference ◽

Artery Disease

Background: The leading cause of mortality in men and women worldwide is coronary artery disease (CAD). For hospitalization in our country, acute coronary syndrome (ACS) is a major reason. Dyslipidemia is found one of the most important modifiable risk factors for CAD. Aim: The aim of the study was to determine the pattern and prevalence of dyslipidemia among patients with ACS admitted in National Institute of Cardiovascular Diseases (NICVD), Dhaka. Subjects and methods: One thousand (1000) patients with ACS were included and classified according to clinical presentation, the findings on the admission electrocardiogram (ECG) and the results of serial cardiac troponin levels, into myocardial infarction(MI), either STelevation or non ST- elevation MI, and unstable angina(UA) subgroups. In the other group 500 healthy subjects were included as controls. All subjects were subjected determination lipid profile. ECG and Troponin- I were done for diagnosis and follow up of the patients. Results: In patients with ACS, high levels of TC (>200 mg/dl) were found in 60.67%,high levels of LDL (> 130 mg/dl) were found in 58%, high levels of TG (>150 mg/ dl) were found in 63.33%, however, low levels of HDL (< 40 mg/dl) were found in 66%. There was a statistically significant elevation in TC, LDL, TG serum levels in patients with ACS compared to control subjects (p<0.05) while the HDL was significantly low in ACS patient compared to control subjects (p <0.05). TC/HDL > 5 and TG/HDL> 4 were significantly higher in patients with ACS than controls. There was no significant difference between MI and UA patients regarding all lipid profile parameters. TC, LDL, TG were significantly higher in males than in females while HDL was significantly higher in females compared to males. Also TC/HDL and TG/HDL ratios were significantly higher in males compared to females. All lipid components were significantly more prevalent in males than in females except TG where there was no significant difference between males and females. Stepwise regression analysis of lipid parameters revealed that TC/HDL and TG/HDL ratios were independent risk factors for ACS. Conclusion: Dyslipidemia is one the major risk factors which is widely prevalent in patients with ACS and is more prevalent in males than in females. We recommend paying more attention to serum lipids and other modifiable risk factors for prevention of ACS and more studies about them as risk factors of atherosclerosis and its impact on other systems is advised. Bangladesh Heart Journal 2019; 34(1) : 31-36

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