Septic shock related to community-acquired pneumonia with ecthyma gangrenosum

It is known that in one-half of the patients hospitalized for community-acquired pneumonia, severe sepsis develops, with non-pulmonary organ dysfunction developing in more than one-third and septic shock in 4.5%. Some years ago, it was found that acute kidney injury was common in community-acquired pneumonia even in patients who appeared to have an uncomplicated course of community-acquired pneumonia and where acute kidney injury was observed in one-quarter of them.

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Ibrutinib-associated necrotic nasal lesion and pulmonary infiltrates

BMJ Case Reports ◽

10.1136/bcr-2020-237085 ◽

2021 ◽

Vol 14 (1) ◽

pp. e237085

Author(s):

Christopher Saling ◽

Fionna Feller ◽

Holenarasipur R Vikram

Keyword(s):

Septic Shock ◽

Pseudomonas Aeruginosa ◽

Blood Culture ◽

Lymphocytic Leukaemia ◽

Invasive Pulmonary Aspergillosis ◽

Necrotic Lesion ◽

Tissue Necrosis ◽

Pulmonary Aspergillosis ◽

Ecthyma Gangrenosum ◽

First Case

Herein, we report a case of a 68-year-old woman receiving ibrutinib for chronic lymphocytic leukaemia, who presented with septic shock and a progressive necrotic lesion on her nose. Surgical pathology of the nasal lesion revealed evidence of tissue necrosis, and both tissue and blood culture grew Pseudomonas aeruginosa. A diagnosis of ecthyma gangrenosum was made. Additional investigations also led to the discovery of invasive pulmonary aspergillosis. To our knowledge, this is the first case of ecthyma gangrenosum secondary to Pseudomonas sepsis and concurrent invasive pulmonary aspergillosis associated with ibrutinib use.

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1709: ECTHYMA GANGRENOSUM AND SEPTIC SHOCK AS PRECEDING SYMPTOMS OF ACUTE LEUKEMIA

Critical Care Medicine ◽

10.1097/01.ccm.0000510382.81814.19 ◽

2016 ◽

Vol 44 (12) ◽

pp. 502-502

Author(s):

Georgia Androutsopoulou ◽

Gloria Heresi ◽

Matthew Greives ◽

Konstantinos Boukas

Keyword(s):

Septic Shock ◽

Acute Leukemia ◽

Ecthyma Gangrenosum

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Severe Community-Acquired Pneumonia due to Acinetobacter baumannii in North America: Case Report and Review of the Literature

Open Forum Infectious Diseases ◽

10.1093/ofid/ofy044 ◽

2018 ◽

Vol 5 (3) ◽

Cited By ~ 12

Author(s):

David P Serota ◽

Mary Elizabeth Sexton ◽

Colleen S Kraft ◽

Federico Palacio

Keyword(s):

Risk Factors ◽

Septic Shock ◽

Acute Respiratory Distress Syndrome ◽

Case Report ◽

North America ◽

Acinetobacter Baumannii ◽

Distress Syndrome ◽

Community Acquired Pneumonia ◽

Review Of The Literature ◽

Severe Community Acquired Pneumonia

Abstract Acinetobacter baumannii is a rare but emerging cause of fulminant community-acquired pneumonia (CAP-AB). We describe a patient from a rural area who developed acute respiratory distress syndrome and septic shock. We describe risk factors and characteristics of this syndrome and review published cases of CAP-AB from North America.

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