The diagnostic accuracy and test-retest reliability of the Dutch PainDETECT and the DN4 screening tools for neuropathic pain in patients with suspected cervical or lumbar radiculopathy

2017 ◽  
Vol 30 ◽  
pp. 72-79 ◽  
Author(s):  
R. Epping ◽  
A.P. Verhagen ◽  
E.A. Hoebink ◽  
S. Rooker ◽  
G.G.M. Scholten-Peeters
2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1746.2-1746
Author(s):  
B. Unver ◽  
K. Sevik ◽  
V. Karatosun

Background:Total knee arthroplasty (TKA) is an effective treatment for patients suffering from end-stage osteoarthritis with 10- to 15-year implant survivorship rates exceeding 90%. Infection, osteolysis due to polyethylene wear, loosening, stiffness and instability may cause to implant failure and revision of the TKA (rTKA). However, up to 20% of patients continue to have postoperative pain, functional limitations and low treatment satisfaction and 24% of patients were not able to walk unaided with no limp or a slight limp after TKA [1].Falls and related traumas can produce “fracture, dislocation, crushing, and other injuries” [2]. Falls often occur due to impaired physical function which includes changes in lower knee joint angle, weakened lower limb muscles, peripheral nerve blockade, deformity of the foot limited balance and gait.Several measures of fall risk have been previously developed however, recent research has demonstrated that backwards walking is more sensitive at identifying changes in mobility and balance compared to forward walking. Backwards walking is necessary to perform such tasks as backing up to a chair, opening up a door or getting out of the way of a sudden obstacle.3-M Backwards Walk Test (3MBWT) is used to evaluate walking skills, fall risk and dynamic balance. The 3MBWT demonstrated similar or better diagnostic accuracy for falls in the past year than the most commonly used measures and found to be reliable in healthy subjects. [3] However, its reliability in rTKA has not been investigated.Objectives:The purposes of this study were to determine the test-retest reliability and the minimal clinically important difference (MCID) of the 3MBWT in patients with rTKAMethods:Twenty-two patients with rTKA, operated on by the same surgeon, were included. For the 3MBWT, a distance of 3 meters was marked with tape and participants were asked to align their heels with the black tape. They were instructed to walk backwards as quickly. Patients performed trials for 3MBWT twice on the same day. Between the trials, patients waited for an hour on sitting position to prevent fatigue.Results:The 3MBWT showed an excellent test-retest reliability. Intraclass correlation coefficient ICC for 3MBWT was 0.97. The standard error of measurement and MCID at the 95% confidence level for 3MBWT were 1,08 and 2,99 respectively.Conclusion:The 3MBWT has an excellent test-retest reliability in patients with rTKA. It is an effective and reliable tool for measuring fall risk, dynamic balance and walking skills. As a clinical test, the 3MBWT is easy to score, has no cost, needs no special equipment and can be applied in a short time as part of the routine medical examination.References:[1]Shan L, Shan B, Suzuki A et al. Intermediate and long-term quality of life after total knee replacement: a systematic review and meta-analysis. JBJS 2015; 97: 156-168.[2]Johnson RL, Duncan CM, Ahn KS et al. Fall-Prevention Strategies and Patient Characteristics That Impact Fall Rates After Total Knee Arthroplasty. Anesthesia & Analgesia 2014; 119: 1113-1118.[3]Carter V, Jain T, James J et al. The 3-m Backwards Walk and Retrospective Falls: Diagnostic Accuracy of a Novel Clinical Measure. J Geriatr Phys Ther 2017.Disclosure of Interests:None declared


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
A. R. Kee ◽  
V. C. H. Yip ◽  
E. L. T. Tay ◽  
C. W. Lim ◽  
J. Cheng ◽  
...  

Abstract Background To understand the differences between two different optical coherence tomography angiography (OCTA) devices in detecting glaucomatous from healthy eyes by comparing their vascular parameters, diagnostic accuracy and test-retest reliability. Methods A cross-sectional observational study was performed on healthy and glaucoma subjects, on whom two sets of OCTA images of optic disc and macula were acquired using both AngioVue (Optovue, USA) and Swept Source (Topcon, Japan) OCTA devices during one visit. A novel in-house software was used to calculate the vessel densities. Diagnostic accuracy of the machines in differentiating healthy versus glaucomatous eyes was determined using area under the receiver operating characteristic curve (AUROC) and test-retest repeatability of the machines was also evaluated. Results A total of 80 healthy and 38 glaucomatous eyes were evaluated. Glaucomatous eyes had reduced mean vessel density compared to healthy controls in all segmented layers of the optic disc and macula using AngioVue (p ≤ 0.001). However, glaucomatous eyes had higher mean vessel density on optic disc scans using Swept Source, with lack of statistically significant difference between healthy and glaucomatous eyes. The AUROC showed better diagnostic accuracy of AngioVue (0.761–1.000) compared to Swept Source (0.113–0.644). The test-retest reliability indices were generally better using AngioVue than Swept Source. Conclusions AngioVue showed better diagnostic capability and test-retest reliability compared to Swept Source. Further studies need to be undertaken to evaluate if there is any significant difference between the various machines in diagnosing and monitoring glaucoma.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Alberto Migliore ◽  
Gianfranco Gigliucci ◽  
Antimo Moretti ◽  
Alessio Pietrella ◽  
Marco Peresson ◽  
...  

Objective. This study aimed to validate Italian versions of Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale and Pain DETECT questionnaire (PD-Q) and evaluate the ability of these questionnaires to discriminate between nociceptive and neuropathic pain. Design. Multicenter prospective validation cohort study. Subjects and Setting. One hundred patients were included with a diagnosis formulated by a specialist in outpatient settings (50 affected by knee osteoarthritis as nociceptive pain and 50 affected by trigeminal or postherpetic neuralgia as neuropathic pain). Methods. The Italian versions of both questionnaires according to Italian cultural characteristics were performed according to the following steps: (1) translation of the questionnaires from English into Italian; (2) review by a bilingual individual for consistency; (3) proposed version after a mail round between experts; (4) backward translation; (5) comparison with the original English version by the experts; (6) approved version of the questionnaires. One hundred patients were enrolled and completed the two questionnaires administered by a specialist or blinded nursing staff, at the baseline and after 24/48 hours. Internal consistency, stability, validity, and discriminative power were analyzed. Results. Statistically significant differences were reported about the ability of both questionnaires to discriminate between patients affected by neuropathic or nociceptive pain. Internal consistency for the Italian version of the LANSS was 0.76, and for PD-Q, it was 0.80, assessed by Cronbach’s α; LANSS showed a good test-retest reliability with an ICC of 0.76, and PD-Q showed a high test-retest reliability with an ICC of 0.96. For interrater reliability, there was a concordance rate of 83.3% between reference diagnosis and LANSS (Cohen’s kappa = 0.67, CI 95% 0.52–0.75). Conclusions. This study validated the Italian versions of LANSS and PD-Q as reliable instruments with good psychometric characteristics, for pain evaluation, discriminating between nociceptive and neuropathic pain. Our findings were similar to those observed in the original study. Furthermore, we have reported the test-retest reliability for both questionnaires, not addressed in original validation studies.


2021 ◽  
pp. bjsports-2020-103840
Author(s):  
Kimberly G Harmon ◽  
Bridget M Whelan ◽  
Douglas F Aukerman ◽  
Adam D Bohr ◽  
J Matthew Nerrie ◽  
...  

ObjectiveTo assess diagnostic accuracy and reliability of sideline concussion tests in college athletes.MethodsAthletes completed baseline concussion tests including Post-Concussion Symptom Scale, Standardised Assessment of Concussion (SAC), modified Balance Error Scoring System (m-BESS), King-Devick test and EYE-SYNC Smooth Pursuits. Testing was repeated in athletes diagnosed acutely with concussion and compared to a matched teammate without concussion.ResultsData were collected on 41 concussed athletes and 41 matched controls. Test–retest reliability for symptom score and symptom severity assessed using control athletes was 0.09 (−0.70 to 0.88) and 0.08 (−1.00 to 1.00) (unweighted kappa). Intraclass correlations were SAC 0.33 (−0.02 to 0.61), m-BESS 0.33 (−0.2 to 0.60), EYE-SYNC Smooth Pursuit tangential variability 0.70 (0.50 to 0.83), radial variability 0.47 (0.19 to 0.69) and King-Devick test 0.71 (0.49 to 0.84). The maximum identified sensitivity/specificity of each test for predicting clinical concussion diagnosis was: symptom score 81%/94% (3-point increase), symptom severity score 91%/81% (3-point increase), SAC 44%/72% (2-point decline), m-BESS 40%/92% (5-point increase), King-Devick 85%/76% (any increase in time) and EYE-SYNC Smooth Pursuit tangential variability 48%/58% and radial variability 52%/61% (any increase). Adjusted area under the curve was: symptom score 0.95 (0.89, 0.99), symptom severity 0.95 (95% CI 0.88 to 0.99), SAC 0.66 (95% CI 0.54 to 0.79), m-BESS 0.71 (0.60, 0.83), King-Devick 0.78 (0.69, 0.87), radial variability 0.47 (0.34, 0.59), tangential variability 0.41 (0.30, 0.54)ConclusionTest–retest reliability of most sideline concussion tests was poor in uninjured athletes, raising concern about the accuracy of these tests to detect new concussion. Symptom score/severity had the greatest sensitivity and specificity, and of the objective tests, the King-Devick test performed best.


Author(s):  
Emma Beard ◽  
Jamie Brown ◽  
Robert West ◽  
Colin Drummond ◽  
Eileen Kaner ◽  
...  

This study compared the 1-item Strength of Urges to Drink (SUTD) scale with the 10-item Alcohol Use Disorders Identification Test (AUDIT) on (i) test-retest reliability, (ii) predictive validity, and (iii) diagnostic accuracy. Data come from 2960 participants taking part in the Alcohol Toolkit Study (ATS), a monthly population survey of adults in England. The long-term test-retest reliability of the SUTD was ‘fair’, but lower than that for the AUDIT (Kappaweighted 0.24 versus 0.49). Individuals with “slight/moderate” urges to drink had higher odds of reporting an attempt to cut down relative to those not experiencing urges (adjusted odds ratios (AdjORs) 1.78 95% confidence interval (CI) 1.43–2.22 and 1.54 95% CI 1.20–1.96). Drinkers reporting “moderate/slight/strong” urges to drink had mean change in consumption scores which were 0.16 (95% CI −0.31 to −0.02), 0.40 (95% CI −0.56 to −0.24) and 0.37 (95% CI −0.69 to −0.05) units lower than those reporting no urges. For all outcomes, strong associations were found with AUDIT scores. The accuracy of the SUTD for discriminating between drinkers who did and did not reduce their consumption was ‘acceptable’, and similar to that for the AUDIT (ROCAUC 0.6). The AUDIT had better diagnostic accuracy in predicting change in alcohol consumption. The SUTD may be an efficient dynamic measure of urges to drink for population surveys and studies assessing the impact of alcohol-reduction interventions.


2020 ◽  
Vol 35 ◽  
pp. 153331752094980
Author(s):  
Gozde Sengul Aycicek ◽  
Hatice Çalıskan ◽  
Cemile Ozsurekci ◽  
Pelin Unsal ◽  
Josef Kessler ◽  
...  

Background and Aim: Mild cognitive impairment (MCI) and dementia prevalence are expected to increase with aging. The DemTect is a very quick and easy tool to administer and recognize the early stages of dementia and MCI. In this study we aimed to evaluate the reliability and validity of a Turkish version of the DemTect and define cut off values for different age and educational levels. One of our aims is also to compare the sensitivity and specifity of the DemTect to other common screening tools. Patients and Methods: Fifty-four patients with MCI, 55 patients with dementia and 91 patients with subjective memory complaints (SMC) were enrolled in the study. The DemTect was translated into Turkish by forward-backward translation and compared with the Mini Mental State Examination (MMSE), the Quick Mild Cognitive Impairment Turkish version (QMCI-TR) and the Montreal Cognitive Assessment (MoCA). In order to test interrater reliability, the DemTect was administered to 11 patients, on the same day, by 2 trained raters. To establish test–retest reliability, the same rater scored the tool a second time on 11 patients within 2 weeks. Results: The median age of the patients was 73 (min-max: 65–90) years, 54.5% were female. We found a strong correlation between DemTect scores and the MMSE, the QMCI, and the MoCA (r = 0.725, r = 0.816, r = 0.821, respectively; p < 0.001). In ROC analysis, the cut-off point of the DemTect to differentiate MCI from SMC was 11.5 with 92.6% sensitivity, 91.2% specificity, AUC 0.973 and the cut-off point of the DemTect to differentiate dementia from SMC was 9.5 with 96.4% sensitivity, 100% specificity, AUC 0.916. Cronbach α was 0.823. Intraclass correlation coefficient was 0.873 (95% CI: 0.598–0.964) for interrater reliability and 0.966 (95% 0.777–0.982) for test-retest reliability (Cronbach α = 0.932, 0.966 respectively). Conclusion: The DemTect is a very reliable tool to assess Turkish patients with MCI and dementia.


2019 ◽  
Vol 19 (3) ◽  
pp. 523-532 ◽  
Author(s):  
Brigitte Tampin ◽  
Rachel Elizabeth Broe ◽  
Lee Lee Seow ◽  
Shushana Gijohn George ◽  
Jiajie Tan ◽  
...  

Abstract Background and aims In 2008, the International Association for the Study of Pain Special Interest Group on Neuropathic Pain (NeuPSIG) proposed a clinical grading system to help identify patients with neuropathic pain (NeP). We previously applied this classification system, along with two NeP screening tools, the painDETECT (PD-Q) and Leeds Assessment of Neuropathic Symptoms and Signs pain scale (LANSS), to identify NeP in patients with neck/upper limb pain. Both screening tools failed to identify a large proportion of patients with clinically classified NeP, however a limitation of our study was the use of a single clinician performing the NeP classification. In 2016, the NeuPSIG grading system was updated with the aim of improving its clinical utility. We were interested in field testing of the revised grading system, in particular in the application of the grading system and the agreement of interpretation of clinical findings. The primary aim of the current study was to explore the application of the NeuPSIG revised grading system based on patient records and to establish the inter-rater agreement of detecting NeP. A secondary aim was to investigate the level of agreement in detecting NeP between the revised NeuPSIG grading system and the LANSS and PD-Q. Methods In this retrospective study, two expert clinicians (Specialist Pain Medicine Physician and Advanced Scope Physiotherapist) independently reviewed 152 patient case notes and classified them according to the revised grading system. The consensus of the expert clinicians’ clinical classification was used as “gold standard” to determine the diagnostic accuracy of the two NeP screening tools. Results The two clinicians agreed in classifying 117 out of 152 patients (ICC 0.794, 95% CI 0.716–850; κ 0.62, 95% CI 0.50–0.73), yielding a 77% agreement. Compared to the clinicians’ consensus, both LANSS and PD-Q demonstrated limited diagnostic accuracy in detecting NeP (LANSS sensitivity 24%, specificity 97%; PD-Q sensitivity 53%, specificity 67%). Conclusions The application of the revised NeP grading system was feasible in our retrospective analysis of patients with neck/upper limb pain. High inter-rater percentage agreement was demonstrated. The hierarchical order of classification may lead to false negative classification. We propose that in the absence of sensory changes or diagnostic tests in patients with neck/upper limb pain, classification of NeP may be further improved using a cluster of clinical findings that confirm a relevant nerve lesion/disease, such as reflex and motor changes. The diagnostic accuracy of LANSS and PD-Q in identifying NeP in patients with neck/upper limb pain remains limited. Clinical judgment remains crucial to diagnosing NeP in the clinical practice. Implications Our observations suggest that in view of the heterogeneity in patients with neck/upper limb pain, a considerable amount of expertise is required to interpret the revised grading system. While the application was feasible in our clinical setting, it is unclear if this will be feasible to apply in primary health care settings where early recognition and timely intervention is often most needed. The use of LANSS and PD-Q in the identification of NeP in patients with neck/upper limb pain remains questionable.


2017 ◽  
Vol 7 (3) ◽  
pp. 339-345 ◽  
Author(s):  
Andreas Ihle ◽  
Élvio R. Gouveia ◽  
Bruna R. Gouveia ◽  
Matthias Kliegel

Aims: The present study set out to evaluate the psychometric properties of the Cognitive Telephone Screening Instrument (COGTEL) in 2 different samples of older adults. Methods: We assessed COGTEL in 116 older adults, with retest after 7 days to evaluate the test-retest reliability. Moreover, we assessed COGTEL in 868 older adults to evaluate convergent validity to the Mini-Mental State Examination (MMSE). Results: Test-retest reliability of the COGTEL total score was good at 0.85 (p < 0.001). Latent variable analyses revealed that COGTEL and MMSE correlated by 0.93 (p < 0.001), indicating convergent validity of the COGTEL. Conclusion: The present analyses suggest COGTEL as a brief, reliable, and valid instrument for capturing interindividual differences in cognitive functioning in epidemiological and aging studies, with the advantage of covering more cognitive domains than traditional screening tools such as the MMSE, as well as differentiating between individual performance levels, in healthy older adults.


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