Biodegradable and self-fluorescent ditelluride-bridged mesoporous organosilica/polyethylene glycol-curcumin nanocomposite for dual-responsive drug delivery and enhanced therapy efficiency

2022 ◽  
Vol 23 ◽  
pp. 100660
Author(s):  
X. Xia ◽  
J. Shi ◽  
Q. Deng ◽  
N. Xu ◽  
F. Huang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Dual Responsive ◽  
Mesoporous Organosilica

Functionalization of mesoporous organosilica nanocarrier for pH/glutathione dual-responsive drug delivery and imaging of cancer therapy process

Talanta ◽  
2018 ◽  
Vol 177 ◽  
pp. 203-211 ◽  
Author(s):  
Lin-Lin Hu ◽  
Jie Meng ◽  
Dan-Dan Zhang ◽  
Ming-Li Chen ◽  
Yang Shu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Therapy Process ◽  
Dual Responsive ◽  
Mesoporous Organosilica

Design of dual-responsive nanocarries with high drug loading capacity based on hollow mesoporous organosilica nanoparticles

2019 ◽  
Vol 233 ◽  
pp. 230-235 ◽  
Author(s):  
Li-li Lu ◽  
Wen-ya Xiong ◽  
Jun-bin Ma ◽  
Tian-fang Gao ◽  
Si-yuan Peng ◽  
...  
Keyword(s):  
Drug Loading ◽  
Loading Capacity ◽  
High Drug ◽  
Dual Responsive ◽  
Mesoporous Organosilica ◽  
High Drug Loading

scholarly journals Polyethylene Glycol Functionalized Graphene Oxide Nanoparticles Loaded with Nigella sativa Extract: A Smart Antibacterial Therapeutic Drug Delivery System

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3067
Author(s):  
Mustafa A. Jihad ◽  
Farah T. M. Noori ◽  
Majid S. Jabir ◽  
Salim Albukhaty ◽  
Faizah A. AlMalki ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Grain Size ◽  
Cell Wall ◽  
Graphene Oxide ◽  
Polyethylene Glycol ◽  
Nucleic Acid ◽  
Drug Delivery System ◽  
Delivery System ◽  
Nigella Sativa ◽  
Seed Extract

Flaky graphene oxide (GO) nanoparticles (NPs) were synthesized using Hummer’s method and then capped with polyethylene glycol (PEG) by an esterification reaction, then loaded with Nigella sativa (N. sativa) seed extract. Aiming to investigate their potential use as a smart drug delivery system against Staphylococcus aureus and Escherichia coli, the spectral and structural characteristics of GO-PEG NPs were comprehensively analyzed by XRD, AFM, TEM, FTIR, and UV- Vis. XRD patterns revealed that GO-PEG had different crystalline structures and defects, as well as a higher interlayer spacing. AFM results showed GONPs with the main grain size of 24.41 nm, while GONPs–PEG revealed graphene oxide aggregation with the main grain size of 287.04 nm after loading N. sativa seed extract, which was verified by TEM examination. A strong OH bond appeared in FTIR spectra. Furthermore, UV- Vis absorbance peaks at (275, 284, 324, and 327) nm seemed to be correlated with GONPs, GO–PEG, N. sativa seed extract, and GO –PEG- N. sativa extract. The drug delivery system was observed to destroy the bacteria by permeating the bacterial nucleic acid and cytoplasmic membrane, resulting in the loss of cell wall integrity, nucleic acid damage, and increased cell-wall permeability.

O-nitrobenzyl Liposomes with Dual-responsive Release Capabilities for Drug Delivery

2021 ◽  
pp. 116016
Author(s):  
Weihe Yao ◽  
Chenyu Liu ◽  
Ning Wang ◽  
Hengjun Zhou ◽  
Farishta Shafiq ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dual Responsive

scholarly journals Injectable Drug Delivery System Based on In Situ Self‐Assembly of Liquid Star Polyethylene Glycol–Poly(lactic‐ co ‐glycolic acid)

2021 ◽  
Vol 1 (3) ◽  
pp. 2170033
Author(s):  
Bat-hen Eylon ◽  
Alona Shagan ◽  
Ayelet Shabtay-Orbach ◽  
Adi Gross ◽  
Boaz Mizrahi
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Drug Delivery System ◽  
Delivery System ◽  
Self Assembly ◽  
Glycolic Acid ◽  
Injectable Drug

A Dual-Responsive Mesoporous Silica Nanoparticle for Tumor-Triggered Targeting Drug Delivery

Small ◽  
2013 ◽  
Vol 10 (3) ◽  
pp. 591-598 ◽  
Author(s):  
Dong Xiao ◽  
Hui-Zhen Jia ◽  
Jing Zhang ◽  
Chen-Wei Liu ◽  
Ren-Xi Zhuo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticle ◽  
Mesoporous Silica Nanoparticle ◽  
Dual Responsive
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