Quantification of different iron forms in the aceruloplasminemia brain to explore iron-related neurodegeneration

This paper focuses on the vertical distribution and characterisation of pedogenic iron forms in a Gleysol- Histosol transect developed in a marshy area in the Danube-Tisza Interfluve, Hungary. Four soil profiles were investigated along a series of increasing waterlogging and spatial and temporal patterns of hydromorphic pedofeatures (characteristics of pedogenic iron forms) were recorded. Frequent and wide-range redox potential (Eh) changes caused the emergence of many types of redoximorphic iron features, including mottles, plaques and nodules. The forms of these features depended on the micro-environments determined by the vertical position in the soil profile and the presence of plant roots. The greatest iron enrichment occurred in the zone of most intensive and widest-range redox fluctuations. Increasing water saturation resulted the extension of gleyic pattern due to the existence of permanent reduction. Most of the features also showed annual variations during the varying periods of water saturation and aeration.

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Abstract W P43: Extent of “Blooming Effect” Predicts Middle Cerebral Artery Recanalization After Intravenous Thrombolysis

Stroke ◽

10.1161/str.46.suppl_1.wp43 ◽

2015 ◽

Vol 46 (suppl_1) ◽

Author(s):

Shenqiang Yan ◽

Min Lou

Keyword(s):

Middle Cerebral Artery ◽

Cerebral Artery ◽

Phase Contrast ◽

Intravenous Thrombolysis ◽

Imaging Data ◽

Blooming Effect ◽

Contrast Enhanced ◽

The Relationship ◽

Delayed Phase ◽

Iron Forms

Background and Purpose: Hemosiderin was shown to have a stronger T2 shortening effect than deoxyhemoglobin. Therefore, the extent of “blooming effect” of susceptibility vessel sign (SVS) might represent composition of different iron forms. We aimed to investigate the relationship between extent of overestimation of thrombus burden and middle cerebral artery (MCA) recanalization. Methods: We retrospectively examined clinical and imaging data from consecutive acute ischemic stroke patients with MCA occlusion who underwent MRI before and 24 hours after IV thrombolysis in our hospital. A delayed phase contrast enhanced T1-WI was used to measure the true size of thrombus. We then examined the association of MCA recanalization and extent of overestimation of thrombus burden. Results: We observed the presence of MCA SVS in 44 patients on initial gradient-recalled echo (GRE) scans and MCA recanalization in 21 (47.7%) patients 24 hours after treatment. The extent of overestimation of thrombus width on GRE was an acceptable predictor for MCA recanalization (odds ratio 1.584 per 10%; 95% CI: 1.090 to 2.310; p=0.016), with a receiver-operator characteristic of 0.884 (95% CI: 0.780 to 0.988; p < 0.001). The optimal cut-off point for predicting recanalization was identified at 1.7814, and this yielded a sensitivity of 87.0% and a specificity of 85.7%. Conclusions: Overestimation of thrombus burden on GRE might reflect the content of hemosiderin. A larger overestimation might indicate aged thrombus, which were resistant to thrombolysis.

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Iron Forms That Influence the Growth and Musty Odor Production of Selected Cyanobacteria

Water Science & Technology ◽

10.2166/wst.1992.0054 ◽

1992 ◽

Vol 25 (2) ◽

pp. 207-216 ◽

Cited By ~ 3

Author(s):

S. Nakashima ◽

M. Yagi

Keyword(s):

Iron Oxides ◽

Ferric Hydroxide ◽

Chelating Agent ◽

Iron Chelator ◽

The Other ◽

Colloidal Iron ◽

Desferrioxamine B ◽

Musty Odor ◽

Iron Forms ◽

Odor Production

In order to clarify the mechanism of growth of musty-odor producing cyanobacteria, the effects of iron forms on growth and musty-odor production in four species of cyanobacteria, Oscillatoriabrevis, Anabaenamacrospora, Phormidiumtenue and Oscillatoriatenuis were studied using laboratory batch cultures. The former two cyanobacteria produce geosmin and the latter two produce 2-methylisoborneol (MIB). The growth of A. macrospora, P. tenue and O. tenuis was suppressed in the EDTA (chelating agent)-free CT medium. However, O. brevis grew well and produced geosmin in this medium as well as in the presence of EDTA. Thus, O. brevis showed an ability to utilize colloidal iron and even iron oxides for its growth. This suggests that O. brevis would be expected to produce a specific high affinity iron chelator (siderophore) in the chelator-free medium. In the presence of bathophenanthroline disulfonate (BPDS), a strong Fe(II) chelating agent, O. brevis and P. tenue were able to grow, but A. macrospora and O.tenuis did not. Furthermore, O.brevis was capable of growing in the medium containing a microbial siderophore, desferrioxamine B(DESF), instead of EDTA, but the other three cyanobacteria did not grow. These results show that O. brevis has an excellent ability to utilize a variety of iron forms including Fe (II I)-EDTA, Fe (II)-BPDS,.Fe (III)-DESF chelates, colloidal ferric hydroxide and more thermodynamically stable crystalline iron oxides (Fe2O3 and Fe3O4) in comparison with the other three musty-odor producing cyanobacteria isolated from Lake Biwa.

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Influences of different iron forms activated peroxydisulfate on volatile fatty acids production during waste activated sludge anaerobic fermentation

The Science of The Total Environment ◽

10.1016/j.scitotenv.2019.135878 ◽

2020 ◽

Vol 705 ◽

pp. 135878 ◽

Cited By ~ 5

Author(s):

Jingyang Luo ◽

Wenxuan Huang ◽

Ying Zhu ◽

Wen Guo ◽

Li Yibing ◽

...

Keyword(s):

Fatty Acids ◽

Activated Sludge ◽

Volatile Fatty Acids ◽

Anaerobic Fermentation ◽

Waste Activated Sludge ◽

Iron Forms

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ABOUT THE RELATIONSHIP OF PHYSICAL AND CHEMICAL PARAMETERS WITH THE CONTENT OF VARIOUS MIGRATION AND OCCURRENCE IRON FORMS IN THE SEA OF AZOV

20th International Multidisciplinary Scientific GeoConference Proceedings SGEM 2020, Ecology, Economics, Education and Legislation ◽

10.5593/sgem2020/5.1/s20.005 ◽

2020 ◽

Author(s):

Yury Fedorov ◽

Leonid Dmitrik ◽

Irina Dotsenko

Keyword(s):

Sea Of Azov ◽

Chemical Parameters ◽

The Sea Of Azov ◽

Physical And Chemical Parameters ◽

Relationship Of ◽

Physical And Chemical ◽

The Relationship ◽

Iron Forms

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TRANSFORMATIONS IN THE Feo/Fed RATIO OF PEDOGENIC IRON OXIDES AFFECTED BY IRON-REDUCING BACTERIA

Canadian Journal of Soil Science ◽

10.4141/cjss78-054 ◽

1978 ◽

Vol 58 (4) ◽

pp. 475-486 ◽

Cited By ~ 22

Author(s):

J. C. MUNCH ◽

Th. HILLEBRAND ◽

J. C. G. OTTOW

Keyword(s):

Particle Size ◽

Iron Oxides ◽

Negative Correlation ◽

Reduction Process ◽

Flooded Soils ◽

Iron Reducing Bacteria ◽

Crystalline Oxides ◽

Reducing Bacteria ◽

Crystalline Forms ◽

Iron Forms

In model experiments under controlled conditions of pH, particle size and amount of glucose, changes in the free Fe oxides (Fed) and acid oxalate soluble Fe (Feo) of six soils were studied after inoculation with iron-reducing, nitrogen-fixing Clostridia. In all soils, the total amount of Fed as well as crystalline Fe (Fed-Feo) decreased immediately and significantly, while Fe(II) in solution increased sigmoidally and was inversely proportional to changes in pH. Feo remained relatively constant throughout the incubation period. As a consequence, the Feo/Fed ratio increased in all samples. At the end of the reduction process, total dissolved Fe(II) correlated with the original Feo content and showed a negative correlation to Fed-Feo. These results are explained by a mechanism in which active non-crystalline iron oxides are reduced in preference to the crystalline forms. The latter are probably transformed and reduced to non-crystalline forms but not until all available active non-crystalline oxides have been exhausted. In the discussion, the reliability of acid oxalate-soluble Fe as a measure of the non-crystalline, active pedogenic iron forms is outlined. Further, the significance of a lowered redox potential (Eh or rH) in reductive transformations of flooded soils is analyzed.

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