A heat shock protein protects against oxidative stress induced by lambda-cyhalothrin in the green peach aphid Myzus persicae

2021 ◽  
pp. 104995
Author(s):  
Bao Dong ◽  
Xi-Ya Liu ◽  
Bin Li ◽  
Mao-Ye Li ◽  
Shi-Guang Li ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Myzus Persicae ◽  
Green Peach Aphid ◽  
Lambda Cyhalothrin

Heat Shock Protein HSP70 in Oxidative Stress in Apnea Patients

2020 ◽  
Vol 169 (5) ◽  
pp. 695-697
Author(s):  
I. M. Madaeva ◽  
N. A. Kurashova ◽  
N. V. Semenova ◽  
E. B. Ukhinov ◽  
S. I. Kolesnikov ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein Hsp70

scholarly journals Recombinant heat shock protein 27 (HSP27/HSPB1) protects against cadmium-induced oxidative stress and toxicity in human cervical cancer cells

2017 ◽  
Vol 22 (3) ◽  
pp. 357-369 ◽  
Author(s):  
Daiana G. Alvarez-Olmedo ◽  
Veronica S. Biaggio ◽  
Geremy A. Koumbadinga ◽  
Nidia N. Gómez ◽  
Chunhua Shi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cervical Cancer ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Cancer Cells ◽  
Heat Shock Protein 27 ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

Effects of ferulic acid on oxidative stress, heat shock protein 70, connexin 43, and monoamines in the hippocampus of pentylenetetrazole-kindled rats

2017 ◽  
Vol 95 (6) ◽  
pp. 732-742 ◽  
Author(s):  
Abdelaziz M. Hussein ◽  
Khaled M. Abbas ◽  
Osama A. Abulseoud ◽  
El-Hussainy M.A. El-Hussainy
Keyword(s):  
Oxidative Stress ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Ferulic Acid ◽  
Group Treatment ◽  
Heat Shock Protein 70 ◽  
Connexin 43 ◽  
Hsp70 Expression ◽  
Neuroprotective Effects ◽  
Cx43 Expression

The present study investigated the effects of ferulic acid (FA) on pentylenetetrazole (PTZ)-induced seizures, oxidative stress markers (malondialdehyde (MDA), catalase, and reduced glutathione (GSH)), connexin (Cx) 43, heat shock protein 70 (Hsp 70), and monoamines (serotonin (5-HT) and norepinephrine (NE)) levels in a rat model of PTZ-induced kindling. Sixty Sprague Dawley rats were divided into 5 equal groups: (a) normal group; (b) FA group: normal rats received FA at a dose of 40 mg/kg daily; (c) PTZ group: normal rats received PTZ at a dose of 50 mg/kg i.p. on alternate days for 15 days; (d) FA-before group: treatment was the same as for the PTZ group, except rats received FA; and (e) FA-after group: rats received FA from sixth dose of PTZ. PTZ caused a significant increase in MDA, Cx43, and Hsp70 along with a significant decrease in GSH, 5-HT, and NE levels and CAT activity in the hippocampus (p < 0.05). Pre- and post-treatment with FA caused significant improvement in behavioral parameters, MDA, CAT, GSH, 5-HT, NE, Cx43 expression, and Hsp70 expression in the hippocampal region (p < 0.05). We conclude that FA has neuroprotective effects in PTZ-induced epilepsy, which might be due to attenuation of oxidative stress and Cx43 expression and upregulation of neuroprotective Hsp70 and neurotransmitters (5-HT and NE).

scholarly journals The chloroplast small heat shock protein undergoes oxidation-dependent conformational changes and may protect plants from oxidative stress

1999 ◽  
Vol 4 (2) ◽  
pp. 129 ◽  
Author(s):  
Ulrika Härndahl ◽  
Roberta Buffoni Hall ◽  
Katherine W. Osteryoung ◽  
Elizabeth Vierling ◽  
Janet F. Bornman ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Conformational Changes ◽  
Small Heat Shock Protein

scholarly journals Exercise protects against doxorubicin-induced oxidative stress and proteolysis in skeletal muscle

2011 ◽  
Vol 110 (4) ◽  
pp. 935-942 ◽  
Author(s):  
Ashley J. Smuder ◽  
Andreas N. Kavazis ◽  
Kisuk Min ◽  
Scott K. Powers
Keyword(s):  
Oxidative Stress ◽  
Skeletal Muscle ◽  
Antioxidant Enzymes ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Oxidative Damage ◽  
Muscle Fibers ◽  
Muscular Exercise ◽  
Protease Activation ◽  
Exercise Induced

Doxorubicin (Dox) is a potent antitumor agent used in cancer treatment. Unfortunately, Dox is myotoxic and results in significant reductions in skeletal muscle mass and function. Complete knowledge of the mechanism(s) by which Dox induces toxicity in skeletal muscle is incomplete, but it is established that Dox-induced toxicity is associated with increased generation of reactive oxygen species and oxidative damage within muscle fibers. Since muscular exercise promotes the expression of numerous cytoprotective proteins (e.g., antioxidant enzymes, heat shock protein 72), we hypothesized that muscular exercise will attenuate Dox-induced damage in exercise-trained muscle fibers. To test this postulate, Sprague-Dawley rats were randomly assigned to the following groups: sedentary, exercise, sedentary with Dox, or exercise with Dox. Our results show increased oxidative stress and activation of cellular proteases (calpain and caspase-3) in skeletal muscle of animals treated with Dox. Importantly, our findings reveal that exercise can prevent the Dox-induced oxidative damage and protease activation in the trained muscle. This exercise-induced protection against Dox-induced toxicity may be due, at least in part, to an exercise-induced increase in muscle levels of antioxidant enzymes and heat shock protein 72. Together, these novel results demonstrate that muscular exercise is a useful countermeasure that can protect skeletal muscle against Dox treatment-induced oxidative stress and protease activation in skeletal muscles.

scholarly journals Photoperiod effects on carcass traits, meat quality, and stress response in heart and lung of broilers

2020 ◽  
Vol 50 (1) ◽  
pp. 138-149
Author(s):  
Y Baykalir ◽  
U.G. Simsek ◽  
M Erisir ◽  
O Otlu ◽  
G Gungoren ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Meat Quality ◽  
Heat Shock Protein 70 ◽  
Carcass Traits ◽  
Continuous Light ◽  
Broiler Chicks ◽  
White Stripe ◽  
White Striping

This study evaluated effects of photoperiod treatments on slaughter and carcass traits, meat quality, indicators of oxidative stress, and heat shock protein 70 (Hsp70) levels of lung and heart tissues in broilers. Five hundred Ross 308 broiler chicks were used. The treatments consisted of 23 hours of continuous light and one hour of darkness (23L1D), four hours of light followed by two hours of darkness (4L2D), eight hours of light and four hours of darkness (8L4D), and 16 hours of light and eight hours of darkness (16L8D). After 42 days, two birds from each replicate were slaughtered. Birds that had been subjected to 16L8D had lower slaughter, carcass, and breast weights than the other treatments. Significant correlations were observed for slaughter, carcass and breast weights and white stripe. At 10 min post mortem, the pH of the breast was the highest in 23L1D. Breasts from birds subjected to 23L1D and 16L8D had most fat and least protein, while white striping was not different among treatments. The 4L2D treatment resulted in the highest lung glutathione (GSH) concentration. Malondialdehyde (MDA) and GSH concentrations in the heart tissues of broilers from 8L4D and 4L2D were greater than those from 23L1D and 16:8. Glutathione peroxidase (GSH-Px) and superoxide dismutase concentrations were greatest for birds subjected to 16L8D. Heat shock protein 70 was lowest in lung and heart from birds subjected to 8L4D. Thus, shorter and more frequent periods of darkness can be recommended for welfare with little compromise in performance. Keywords: carcass quality, heat shock protein 70, oxidative stress, white stripe

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