Getting to grips with grip strength: A scoping review of patients mapped against sarcopenia consensus cut points

Physiotherapy ◽  
2021 ◽  
Vol 113 ◽  
pp. e61
Author(s):  
J. Thomas ◽  
L. Martin ◽  
G. Muir
Keyword(s):  
Grip Strength ◽  
Scoping Review ◽  
Cut Points

scholarly journals Sarcopenia Characteristics Are Associated with Incident Mobility Limitations in African Caribbean Men: The Tobago Longitudinal Study of Aging

2019 ◽  
Vol 75 (7) ◽  
pp. 1346-1352
Author(s):  
Adam J Santanasto ◽  
Iva Miljkovic ◽  
Ryan K Cvejkus ◽  
Victor W Wheeler ◽  
Joseph M Zmuda
Keyword(s):  
Grip Strength ◽  
Body Mass ◽  
African Ancestry ◽  
The United States ◽  
National Institutes Of Health ◽  
Linear Regression Models ◽  
Mobility Limitations ◽  
Cut Points ◽  
European Working ◽  
African Caribbean

Abstract Background Sarcopenia varies by ethnicity, and has a major impact on health in older adults. However, little is known about sarcopenia characteristics in African ancestry populations outside the United States. We examined sarcopenia characteristics in 2,142 African Caribbean men aged 59.0 ± 10.4 years (range: 40–92 years) in Tobago, and their association with incident mobility limitations in those aged 55+ (n = 738). Methods Body mass index (BMI), grip strength, dual-x-ray absorptiometry (DXA) appendicular lean mass (ALM), and self-reported mobility limitations were measured at baseline, and 6 years later. Change in sarcopenia characteristics, including grip strength, grip strength/BMI, ALMBMI, and ALM/ht2, were determined. Foundations for the National Institutes of Health Sarcopenia Project (FNIH) and European Working Group for Sarcopenia in Older People 2 (EWGSOP2) cut-points were also examined. Odds ratios (OR) and 95% confidence intervals (CI) for mobility limitation were calculated using multivariable linear regression models adjusted for covariates. Results Overall, sarcopenia prevalence was quite low using the FNIH (0.3%) and EWGSOP2 (0.6%) operational cut-points, but was higher in those aged 75+ (2.1% [FNIH] and 3.7% [EWGSOP2]). Prevalence was also higher when based on “weakness”, versus “low ALM.” When sarcopenia markers were examined separately, baseline levels, but not changes, were associated with incident mobility limitations. Baseline grip strength/BMI was a particularly strong risk factor for incident mobility limitations (OR per SD: 0.50; 95% CI: 0.37–0.68). Conclusions Our findings suggest that grip strength normalized to body mass, measured at one time point, may be a particularly useful phenotype for identifying African Caribbean men at risk for future mobility limitations.

Grip Strength Cut Points for Diabetes Risk Among Apparently Healthy U.S. Adults

2020 ◽  
Vol 58 (6) ◽  
pp. 757-765 ◽  
Author(s):  
Elise C. Brown ◽  
Duncan S. Buchan ◽  
Samar A. Madi ◽  
Breanne N. Gordon ◽  
Dorin Drignei
Keyword(s):  
Grip Strength ◽  
Diabetes Risk ◽  
Cut Points ◽  
Apparently Healthy

scholarly journals Prevalence of Sarcopenia Obesity in Patients Treated at a Rural, Multidisciplinary Weight and Wellness Center

2019 ◽  
Vol 12 ◽  
pp. 117954411986228
Author(s):  
John A Batsis ◽  
Diane Gilbert-Diamond ◽  
Auden C McClure ◽  
Aaron Weintraub ◽  
Diane Sette ◽  
...  
Keyword(s):  
Grip Strength ◽  
Body Fat ◽  
Tertiary Care ◽  
Bioelectrical Impedance ◽  
Impedance Analysis ◽  
Fat Free Mass ◽  
Sarcopenic Obesity ◽  
Cut Points ◽  
Sit To Stand ◽  
Wellness Center

Sarcopenic obesity portends poor outcomes, yet it is under-recognized in practice. We collected baseline clinical data including data on body composition (total and segmental muscle mass and total body fat), grip strength, and 5-times sit-to-stand. We defined sarcopenia using cut-points for appendicular lean mass (ALM) and obesity using body-fat cut-points. A total of 599 clinic patients (78.5% female; mean age was 51.3 ± 14.2 years) had bioelectrical impedance analysis (BIA) data (83.8%). Mean body mass index (BMI) and waist circumference were 43.1 ± 8.9 kg/m2 and 132.3 ± 70.7 cm, respectively. All patients had elevated body fat. There were 284 (47.4%) individuals fulfilling criteria for ALM-defined sarcopenia. Sarcopenic obese persons had a lower BMI (38.2 ± 6.4 vs 47.6 ± 8.6; P < 0.001), fat-free mass (113.0 kg ± 16.1 vs 152.1 kg ± 29.4; P < 0.001), fat mass (48.4% ± 5.9 vs 49.5% ± 6.2; P = 0.03), and visceral adipose tissue (216.8 ± 106.3 vs 242.7 ± 133.6 cm3; P = 0.009) than those without sarcopenic obesity. Grip strength was lower in those with sarcopenic obesity (25.1 ± 8.0 vs 30.5 ± 11.3 kg; P < 0.001) and sit-to-stand times were longer (12.4 ± 4.4 vs 10.8 second ± 4.6; P = 0.03). Sarcopenic obesity was highly prevalent in a rural, tertiary care weight and wellness center.

scholarly journals Establishing the Link Between Lean Mass and Grip Strength Cut Points With Mobility Disability and Other Health Outcomes: Proceedings of the Sarcopenia Definition and Outcomes Consortium Conference

2019 ◽  
Vol 75 (7) ◽  
pp. 1317-1323 ◽  
Author(s):  
Peggy M Cawthon ◽  
Thomas G Travison ◽  
Todd M Manini ◽  
Sheena Patel ◽  
Karol M Pencina ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Grip Strength ◽  
Body Mass ◽  
Lean Mass ◽  
Risk Model ◽  
Evidence Based ◽  
Mobility Disability ◽  
Cut Points ◽  
Increased Risk ◽  
Definition Of

Abstract Background Lack of consensus on how to diagnose sarcopenia has limited the ability to diagnose this condition and hindered drug development. The Sarcopenia Definitions and Outcomes Consortium (SDOC) was formed to develop evidence-based diagnostic cut points for lean mass and/or muscle strength that identify people at increased risk of mobility disability. We describe here the proceedings of a meeting of SDOC and other experts to discuss strategic considerations in the development of evidence-based sarcopenia definition. Methods Presentations and panel discussions reviewed the usefulness of sarcopenia as a biomarker, the analytical approach used by SDOC to establish cut points, and preliminary findings, and provided strategic direction to develop an evidence-based definition of sarcopenia. Results The SDOC assembled data from eight epidemiological cohorts consisting of 18,831 participants, clinical populations from 10 randomized trials and observational studies, and 2 nationally representative cohorts. In preliminary assessments, grip strength or grip strength divided by body mass index was identified as discriminators of risk for mobility disability (walking speed &lt;0.8 m/s), whereas dual-energy X-ray absorptiometry-derived lean mass measures were not good discriminators of mobility disability. Candidate definitions based on grip strength variables were associated with increased risk of mortality, falls, mobility disability, and instrumental activities of daily living disability. The prevalence of low grip strength increased with age. The attendees recommended the establishment of an International Expert Panel to review a series of position statements on sarcopenia definition that are informed by the findings of the SDOC analyses and synthesis of literature. Conclusions International consensus on an evidence-based definition of sarcopenia is needed. Grip strength—absolute or adjusted for body mass index—is an important discriminator of mobility disability and other endpoints. Additional research is needed to develop a predictive risk model that takes into account sarcopenia components as well as age, sex, race, and comorbidities.

scholarly journals Application of SDOC Cut Points for Low Muscle Strength for Recovery of Walking Speed After Hip Fracture

2020 ◽  
Vol 75 (7) ◽  
pp. 1379-1385 ◽  
Author(s):  
Denise L Orwig ◽  
Jay Magaziner ◽  
Roger A Fielding ◽  
Hao Zhu ◽  
Ellen F Binder ◽  
...  
Keyword(s):  
Hip Fracture ◽  
Muscle Strength ◽  
Grip Strength ◽  
Walking Speed ◽  
High Sensitivity ◽  
Community Dwelling ◽  
Meaningful Change ◽  
Cut Points ◽  
Speed Performance ◽  
Total Body

Abstract Background Sarcopenia is often conceptualized as a precursor to loss of mobility, but its effect on recovery of mobility after a hip fracture is unknown. We determined the prevalence of low muscle strength (weakness) after hip fracture using putative sarcopenia metrics (absolute grip strength, and grip strength normalized to body mass index, total body fat, arm lean mass, and weight) identified by the Sarcopenia Definitions and Outcomes Consortium (SDOC). Methods We examined two well-characterized hip fracture cohorts of community-dwelling older adults from the Baltimore Hip Studies (BHS). The prevalence of muscle weakness was assessed using the SDOC cut points compared to published definitions at 2 and 6 months postfracture. We assessed associations of 2-month weakness with 6-month walking speed &lt;0.6 m/s and calculated the sensitivity and specificity in predicting lack of meaningful change in walking speed (change &lt; 0.1 m/s) at 6 months. Results Two hundred and forty-six participants (192 women; 54 men) were included; mean (SD) age of 81 (8) for women and 78 (7) for men. At 2 months, 91% women and 78% men exhibited slow walking speed (&lt; 0.6 m/s). SDOC grip strength standardized by weight (&lt;0.34 kg women, &lt;0.45 kg men) was the most prevalent measure of weakness in men (74%) and women (79%) and provided high sensitivity in men (86%) and women (84%) predicting lack of meaningful change in walking speed at 6 months, although specificity was poor to moderate. Conclusions SDOC cut points for grip strength standardized to weight provided consistent indication of poor walking speed performance post-hip fracture.

scholarly journals Hand-Grip Strength Cut Points to Screen Older Persons at Risk for Mobility Limitation

2010 ◽  
Vol 58 (9) ◽  
pp. 1721-1726 ◽  
Author(s):  
Janne Sallinen ◽  
Sari Stenholm ◽  
Taina Rantanen ◽  
Markku Heliövaara ◽  
Päivi Sainio ◽  
...  
Keyword(s):  
At Risk ◽  
Grip Strength ◽  
Older Persons ◽  
Hand Grip Strength ◽  
Mobility Limitation ◽  
Cut Points ◽  
Hand Grip

scholarly journals Performance of the EWGSOP2 Cut-Points of Low Grip Strength for Identifying Sarcopenia and Frailty Phenotype: A Cross-Sectional Study in Older Inpatients

2021 ◽  
Vol 18 (7) ◽  
pp. 3498
Author(s):  
Anna K. Stuck ◽  
Nina C. Mäder ◽  
Dominic Bertschi ◽  
Andreas Limacher ◽  
Reto W. Kressig
Keyword(s):  
Grip Strength ◽  
Gait Speed ◽  
Older Patients ◽  
Care Hospital ◽  
Frailty Phenotype ◽  
Cross Sectional ◽  
Cut Points ◽  
Cut Point ◽  
European Working ◽  
Definition Of

Background: The European Working Group on Sarcopenia has recently proposed revised cut-off values for the definition of low grip strength (EWGSOP2). We therefore compared performance of the EWGSOP2 cut-off definition of low grip strength with other internationally used cut-off points in a sample of older patients. Methods: We analyzed geriatric assessment data in a cross-sectional sample of 98 older patients admitted to a post-acute care hospital. First, we compared prevalence of sarcopenia and frailty phenotype in our sample using low grip strength cut-points from the EWGSOP2 and seven other internationally used consensus statements. Second, we calculated correlations between low grip strength and two independent surrogate outcomes (i.e., gait speed, and the clinical frailty scale) for the EWGSOP2 and the other seven cut-point definitions. Results: Prevalence of sarcopenia based on the EWGSOP2 grip strength cut-off values was significantly lower (10.2%) than five of the seven other cut-point definitions (e.g., 19.4% based on Sarcopenia Definitions and Outcomes Consortium (SDOC) criteria). Similarly, frailty phenotype prevalence was significantly lower based on EWGSOP2 cut-points (57.1%) as compared to SDOC (70.4%). The correlation coefficient of gait speed with low grip strength based on EWGSOP2 cut-points was lower (0.145) as compared to other criteria (e.g., SDOC 0.240). Conclusions: Sarcopenia and frailty phenotype were identified considerably less using the EWGSOP2 cut-points for low grip strength, potentially underestimating prevalence of sarcopenia and frailty phenotype in post-acute hospital patients.

Measurement of hand grip strength in the elderly: A scoping review with recommendations

2020 ◽  
Vol 24 (1) ◽  
pp. 235-243 ◽  
Author(s):  
Hanife Mehmet ◽  
Angela W.H. Yang ◽  
Stephen R. Robinson
Keyword(s):  
Grip Strength ◽  
Scoping Review ◽  
The Elderly ◽  
Hand Grip Strength ◽  
Hand Grip

scholarly journals Self-Reported Health and Sarcopenia Phenotypes: Data From the National Health and Aging Trends Survey

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 178-179
Author(s):  
John Batsis ◽  
Cameron Dowd-Sivigny ◽  
Christian Haudenschild ◽  
Rebecca Crow ◽  
Tyler Gooding ◽  
...  
Keyword(s):  
Grip Strength ◽  
National Health ◽  
Functional Decline ◽  
World Health ◽  
Sarcopenic Obesity ◽  
Cut Points ◽  
Logistic Regression Models ◽  
Age Related ◽  
Reported Health ◽  
Fair Poor

Abstract Background: Obesity in combination with sarcopenia (age-related loss of muscle mass, strength or function) is increasing in adults aged ≥65 years which places individuals at risk for functional decline and worse health. We ascertained the relationship between sarcopenic obesity and self-reported health in a representative US population. Methods: We identified participants ≥65 years with grip strength and body mass index (BMI) measures from the baseline wave of the National Health and Aging Trends Survey. Sarcopenia was defined using the Sarcopenia Definitions and Outcomes Consortium grip strength cut-points (males&lt;35.5kg; females&lt;20kg), and obesity was defined using standard World Health Organization BMI categories. We also assessed grip divided by BMI cut-points (males&lt;1.05; females&lt;0.79). Self-reported health was evaluated using a one-item question (Excellent/Very Good/Good vs. Fair/Poor). Logistic regression models adjusted for age, sex, smoking, education, comorbidities, and an ability to walk. Results: Of the 8,245 participants (59.7% female), median age category was 75-79, and mean grip strength and BMI were 26.0 kg and 27.0 kg/m2, respectively. Prevalence of sarcopenia and sarcopenic obesity was 12.7% and 41.1%. Compared to those without sarcopenia or obesity, the odds of impaired self-reported health using grip strength defined sarcopenia cut-points was higher in sarcopenic obesity (OR 1.87 [1.50,2.32]), sarcopenia (OR 1.79 [1.50,2.14]), and obesity (OR 1.24 [0.99,1.56]). Using the Grip divided by BMI cutpoints, we found the odds of low self-reported health in sarcopenia was OR 1.38 [1.12, 1.59]. Conclusions: Both sarcopenia and sarcopenic obesity are associated with an increased odds of decreased self-reported health.

Sign in / Sign up

Export Citation Format

Share Document