Application and mechanism of benzyl-isothiocyanate, a natural antimicrobial agent from cruciferous vegetables, in controlling postharvest decay of strawberry

2021 ◽  
Vol 180 ◽  
pp. 111604
Author(s):  
Yaya Sun ◽  
Ying Wang ◽  
Yong Xu ◽  
Tong Chen ◽  
Boqiang Li ◽  
...  
Keyword(s):  
Antimicrobial Agent ◽  
Cruciferous Vegetables ◽  
Natural Antimicrobial ◽  
Benzyl Isothiocyanate ◽  
Postharvest Decay

Non-Genotoxic Assessment of a Natural Antimicrobial Agent: Squalamine

2014 ◽  
Vol 12 (1) ◽  
pp. 75-79 ◽  
Author(s):  
Kamel Alhanout ◽  
Carole D. Giorgio ◽  
Michel D. Meo ◽  
Jean M. Brunel
Keyword(s):  
Antimicrobial Agent ◽  
Natural Antimicrobial

scholarly journals FROM CHITIN TO CHITOSAN – A POTENTIAL NATURAL ANTIMICROBIAL AGENT

2021 ◽  
Vol 26 ◽  
pp. 23-40
Author(s):  
Zofia Nuc ◽  
◽  
Aldona Dobrzycka-Krahel
Keyword(s):  
Antimicrobial Agent ◽  
Wide Spectrum ◽  
Antimicrobial Properties ◽  
Multidrug Resistant ◽  
Modern Medicine ◽  
Natural Antimicrobial ◽  
Current State ◽  
Naturally Occurring ◽  
Alternative Sources ◽  
Many Sources

Chitin is a naturally occurring polymer. Together with its derivatives such as chitosan, it has a wide spectrum of application possibilities, and many properties not yet exploited. Chitosan possesses many features desirable in an ideal antimicrobial polymer. It shows activity against multidrug-resistant bacterial and fungal strains that pose a challenge to modern medicine. Chitosan also shows activity against certain viruses, such as SARS-CoV-2. It might be used as a drug or a vaccine delivery system, is biodegradable, bioavailable and considered safe for medical use. It is important to continue exploring the potential of chitosan, as well as to investigate its sources. Indeed, many sources of this polymer are still not or have been poorly described. In this paper, we compile the current state of knowledge on the antimicrobial properties of chitosan, list alternative sources of chitin to highlight the potential of these two polymers and encourage further research.

scholarly journals Insights into the Mode of Action of Benzyl Isothiocyanate on Campylobacter jejuni

2013 ◽  
Vol 79 (22) ◽  
pp. 6958-6968 ◽  
Author(s):  
Virginie Dufour ◽  
Martin Stahl ◽  
Eric Rosenfeld ◽  
Alain Stintzi ◽  
Christine Baysse
Keyword(s):  
Energy Metabolism ◽  
Campylobacter Jejuni ◽  
Cellular Response ◽  
Gastrointestinal Diseases ◽  
Natural Antimicrobial ◽  
Transcriptomic Response ◽  
Benzyl Isothiocyanate ◽  
Promising Alternative ◽  
Content Type ◽  
Food Borne

ABSTRACTCampylobacter jejuniis a widespread pathogen responsible for most of the food-borne gastrointestinal diseases in Europe. The use of natural antimicrobial molecules is a promising alternative to antibiotic treatments for pathogen control in the food industry. Isothiocyanates are natural antimicrobial compounds, which also display anticancer activity. Several studies described the chemoprotective effect of isothiocyanates on eukaryotic cells, but the antimicrobial mechanism is still poorly understood. We investigated the early cellular response ofC. jejunito benzyl isothiocyanate by both transcriptomic and physiological approaches. The transcriptomic response ofC. jejunito benzyl isothiocyanate showed upregulation of heat shock response genes and an impact on energy metabolism. Oxygen consumption was progressively impaired by benzyl isothiocyanate treatment, as revealed by high-resolution respirometry, while the ATP content increased soon after benzyl isothiocyanate exposition, which suggests a shift in the energy metabolism balance. Finally, benzyl isothiocyanate induced intracellular protein aggregation. These results indicate that benzyl isothiocyanate affectsC. jejuniby targeting proteins, resulting in the disruption of major metabolic processes and eventually leading to cell death.

scholarly journals Citrus microcarpa Extract as Immunostimulator in Controlling Edwardsiellosis in African Catfish Culture

2015 ◽  
Vol 2 (2) ◽  
pp. 68-71
Author(s):  
Seong Wei Lee ◽  
MN An’amt ◽  
Wee Wendy ◽  
A.K. Zulhisyam
Keyword(s):  
Antibody Response ◽  
Antimicrobial Agent ◽  
Edwardsiella Tarda ◽  
Enzyme Linked Immunosorbent Assay ◽  
African Catfish ◽  
Bacterial Disease ◽  
Natural Antimicrobial ◽  
Cumulative Mortality ◽  
Experimental Fish ◽  
Cultured Fish

This study was described Citrus microcarpa extract as an antimicrobial agent in controlling edwardsiellosis in African catfish culture. Edwardsiellosis due to Edwardsiella tarda was recognized as a problem in African catfish culture and may lead to mass mortality of the cultured fish. Many antibiotics were no longer effective to control this bacterial disease. Therefore, this study was carried out to investigate the potential of C. microcarpa extract to overcome this bacterial disease problem. The experimental fish were fed with medicated feed at three different concentrations (1 g kg-1; CM-1, 2 g kg-1; CM-2 and 4 g kg-1 of fish) of C. microcarpa extract for one week before they were intraperitoneally exposed to E. tarda. Enzyme linked immunosorbent assay (ELISA) was carried out to determine the value of antibody response to E. tarda in fish from group of fish that received medicated fish and the percentage of total cumulative mortality of the experimental fish were observed at the end of the experiment. The results showed that the value of antibody response to E. tarda in fish from group of fish which received medicated feed (CM-1, 0.148 ± 0.017 OD; CM-2, 0.143 ± 0.006 OD; CM-4, 0.163 ± 0.015 OD) were found significantly higher (P < 0.05) compared to fish did not received medicated fish (0.00 OD). Whereas, percentage cumulative mortality of fish from all groups of fish received medicated feed (CM-1, 20.0 ± 10.0 %; CM-2, 16.7 ± 5.8 %; CM-4, 16.7 ± 5.8 %) were found significantly lower (P < 0.05) compared to group of fish did not received medicated feed (56.7 ± 5.8 %). The findings of the present study indicated the huge potential of C. microcarpa extract as natural antimicrobial agent for aquaculture use.

Microbiological and Physicochemical Quality Changes in Frankfurters Made from Jumbo Squid (D osidicus gigas ) Mantle Muscle in the Presence and Absence of a Natural Antimicrobial Agent

2015 ◽  
Vol 35 (4) ◽  
pp. 473-481 ◽  
Author(s):  
Juan Carlos Ramírez-Suárez ◽  
Ramón Pacheco-Aguilar ◽  
Susana María Scheuren-Acevedo ◽  
Guillermina García-Sánchez ◽  
Gisela Carvallo-Ruiz ◽  
...  
Keyword(s):  
Antimicrobial Agent ◽  
Quality Changes ◽  
Natural Antimicrobial ◽  
Physicochemical Quality ◽  
Jumbo Squid ◽  
Presence And Absence
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