scholarly journals Changes in electromyographical activity during different phases of orthodontic treatment: pilot study results

2017 ◽  
Vol 5 (4) ◽  
pp. e233-e239
Author(s):  
Claudia Ivonne Rodríguez Castañeda ◽  
Luis Pablo Cruz Hervert ◽  
Eduardo Llamosas Hernández ◽  
David Elías Viñas ◽  
Luis Antonio García Espinosa ◽  
...  
Keyword(s):  
Pilot Study ◽  
Orthodontic Treatment ◽  
Study Results

Biotower Pilot Study Results for a Photographic and Specialty Paper Manufacturer

1992 ◽  
Vol 26 (9-11) ◽  
pp. 2109-2112
Author(s):  
J. G. Cleary ◽  
T. J. Boehm ◽  
R. J. Geary
Keyword(s):  
New York ◽  
Pilot Study ◽  
New York State ◽  
Cross Flow ◽  
Full Scale ◽  
Treatment System ◽  
Salmon River ◽  
Study Results ◽  
Comparable Performance ◽  
Pollutant Discharge

Schoeller Technical Papers, Inc. (Schoeller), which manufactures photographic and other specialty papers, is located in Pulaski, New York. The wastewater treatment system consists of a primary clarifier and two settling lagoons. Secondary treatment using a biotower was proposed to meet the new New York State Pollutant Discharge Elimination System (SPDES) discharge limits for BOD and TSS. The effluent from each basin is discharged directly to the Salmon River, at an approximate average flow of 1.6 million gallons/day (mgd). A biotower pilot study was performed to evaluate the suitability of a biotower treatment process for treating the total effluent from Schoeller's facility. The pilot study was used to select the media for the full-scale biotower and to confirm the design loading for the full-scale biotower, which proceeded in parallel with the pilot study due to the schedule constraints. Two pilot systems were operated to compare a conventional cross-flow and vertical media. Test data were collected to evaluate the performance of each pilot treatment system at a range of loading conditions and to develop the design loading information for the full-scale plant. The pilot units were operated for a period of 10 months. BOD concentrations to the pilot units averaged 58 mg/l with a peak of 210 mg/l. Approximately 80% of the BOD was soluble. BOD loadings averaged 21 lb BOD/day/1,000 cubic feet with a peak of 77 lb BOD/day/1,000 cubic feet. Both pilot units achieved excellent BOD removals exceeding 75%, with average effluent soluble BOD concentration less than 10 mg/l and average effluent TSS concentrations of 12 mg/l. The two media achieved comparable performance throughout most of the pilot study.

scholarly journals Symptom Cluster-Matching Antidepressant Treatment: A Case Series Pilot Study

2021 ◽  
Vol 14 (6) ◽  
pp. 526
Author(s):  
Sławomir Murawiec ◽  
Marek Krzystanek
Keyword(s):  
Depressive Symptoms ◽  
Pilot Study ◽  
Antidepressant Treatment ◽  
Case Series ◽  
Symptom Cluster ◽  
Study Results ◽  
Cluster Matching ◽  
The Individual ◽  
Meta Analyses ◽  
Effectiveness Studies

Despite treating depression with antidepressants, their effectiveness is often insufficient. Comparative effectiveness studies and meta-analyses show the effectiveness of antidepressants; however, they do not provide clear indications as to the choice of a specific antidepressant. The rational choice of antidepressants may be based on matching their mechanisms of action to the symptomatic profiles of depression, reflecting the heterogeneity of symptoms in different patients. The authors presented a series of cases of patients diagnosed with depression in whom at least one previous antidepressant treatment was shown to be ineffective before drug targeted symptom cluster-matching treatment (SCMT). The presented pilot study shows for the first time the effectiveness of SCMT in the different clusters of depressive symptoms. All the described patients obtained recovery from depressive symptoms after introducing drug-targeted SCMT. Once validated in clinical trials, SCMT might become an effective and rational method of selecting an antidepressant according to the individual profile of depressive symptoms, the mechanism of their formation, and the mechanism of drug action. Although the study results are preliminary, SCMT can be a way to personalize treatment, increasing the likelihood of improvement even in patients who meet criteria for treatment-resistant depression.

scholarly journals DNA methylation and behavioral dysfunction in males with 47,XXY and 49,XXXXY: a pilot study

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Richard S. Lee ◽  
Sophia Q. Song ◽  
Henri M. Garrison-Desany ◽  
Jenny L. Carey ◽  
Patricia Lasutschinkow ◽  
...  
Keyword(s):  
Pilot Study ◽  
X Chromosome ◽  
Child Behavior Checklist ◽  
Epigenetic Modification ◽  
Cpg Methylation ◽  
Monoamine Oxidase A ◽  
Low Fertility ◽  
X Chromosomes ◽  
Behavioral Dysfunction ◽  
Study Results

Abstract Background Equal dosage of X-linked genes between males and females is maintained by the X-inactivation of the second X chromosome in females through epigenetic mechanisms. Boys with aneuploidy of the X chromosome exhibit a host of symptoms such as low fertility, musculoskeletal anomalies, and cognitive and behavioral deficits that are presumed to be caused by the abnormal dosage of these genes. The objective of this pilot study is to assess the relationship between CpG methylation, an epigenetic modification, at several genes on the X chromosome and behavioral dysfunction in boys with supernumerary X chromosomes. Results Two parental questionnaires, the Behavior Rating Inventory of Executive Function (BRIEF) and Child Behavior Checklist (CBCL), were analyzed, and they showed expected differences in both internal and external behaviors between neurotypical (46,XY) boys and boys with 49,XXXXY. There were several CpGs in AR and MAOA of boys with 49,XXXXY whose methylation levels were skewed from levels predicted from having one active (Xa) and three inactive (Xi) X chromosomes. Further, methylation levels of multiple CpGs in MAOA showed nominally significant association with externalizing behavior on the CBCL, and the methylation level of one CpG in AR showed nominally significant association with the BRIEF Regulation Index. Conclusions Boys with 49,XXXXY displayed higher levels of CpG methylation at regulatory intronic regions in X-linked genes encoding the androgen receptor (AR) and monoamine oxidase A (MAOA), compared to that in boys with 47,XXY and neurotypical boys. Our pilot study results suggest a link between CpG methylation levels and behavior in boys with 49,XXXXY.

scholarly journals Knowledge, Attitudes, Behaviors of Women Related to Pregnancy, and Early Childhood Caries Prevention: A Cross-Sectional Pilot Study

2021 ◽  
Vol 12 ◽  
pp. 215013272110133
Author(s):  
Neel Shimpi ◽  
Ingrid Glurich ◽  
Catherine Maybury ◽  
Min Qi Wang ◽  
Kazumasa Hashimoto ◽  
...  
Keyword(s):  
Oral Health ◽  
Pilot Study ◽  
Health Education ◽  
Survey Study ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Health Maintenance ◽  
Significance Level ◽  
Study Results ◽  
And Behaviors

Objective Health education interventions during pregnancy can influence maternal oral health (OH), maternal OH-behaviors and children’s OH. Interventions that can be delivered at anytime and anywhere, for example mobile-health (mHealth) provides an opportunity to address challenges of health education and support activation of women in underserved and rural communities to modify their health behavior. This pilot study was undertaken as a part of a mHealth initiative to determine knowledge, attitudes, and behaviors related to pregnancy and ECC prevention among women attending obstetrics/gynecology (OB/GYN) practices at a large rurally-based clinic. Methods A cross-sectional survey study was voluntarily engaged by women (n = 191) aged 18 to 59 years attending OB/GYN visits, over a 3-week period from 12/2019 to 1/2020. Survey results were analyzed applying descriptive statistics, X2 and Fisher’s Exact tests. The significance level was set at P < .0001 for all analyses. Results Approximately half of respondents were between 18 and 29 years (53%), had a college degree (55%), and 100% reported cell phone use. Whereas 53% and 31%, respectively, indicated that they were “somewhat” or “very” sure of how to prevent ECC in their children, only 9% recognized evidence of early decay and 30% did not know the purpose of fluoride. Overall, only 27% of participants correctly answered the knowledge-based questions. Further, only 57% reported their provider explained things in a way that was easy to understand. Only 24% reported seeing a dentist during their current pregnancy. Conclusions Study results suggested potential gaps in knowledge and behaviors related to ECC prevention and provided baseline data to inform future interventions to improve ECC prevention practices. Notably, majority of participants used their cell phones for making medical/dental appointments and reported using their phones to look up health-related information. This demographic represents a potentially receptive target for mHealth approaches to improve understanding of oral health maintenance during pregnancy and ECC prevention.

National Standards for Diabetes Patient Education Programs: Pilot Study Results and Implementation Plan

1986 ◽  
Vol 12 (3) ◽  
pp. 292-296 ◽  
Author(s):  
Nina Berlin ◽  
Dorothea Sims ◽  
James Belloni ◽  
Jerry Brimberry ◽  
Donnell Etzwiler ◽  
...  
Keyword(s):  
Pilot Study ◽  
Patient Education ◽  
Diabetes Patient ◽  
National Standards ◽  
Education Programs ◽  
Implementation Plan ◽  
Study Results

Task path theory: further pilot study results analysis

Work Study ◽  
2000 ◽  
Vol 49 (1) ◽  
pp. 10-14
Author(s):  
David R. Moore
Keyword(s):  
Pilot Study ◽  
Study Results

It takes two to tango: The therapeutic alliance in community brain injury rehabilitation

2021 ◽  
pp. 1-18
Author(s):  
Liz M. Williams ◽  
Jacinta M. Douglas
Keyword(s):  
Brain Injury ◽  
Pilot Study ◽  
Therapeutic Alliance ◽  
Qualitative Methodology ◽  
Rehabilitation Programme ◽  
Injury Rehabilitation ◽  
Community Rehabilitation ◽  
Purposeful Sampling ◽  
Study Results ◽  
Working Together

Abstract Objective: A positive therapeutic (or working) alliance has been associated with better outcomes for clients in the psychotherapeutic and traumatic brain injury (TBI) rehabilitation literature. The aim of this pilot study was to gain an understanding of the therapeutic alliance in community rehabilitation from the perspectives of adults with TBI and their close others who have completed a community rehabilitation programme. Method: This study used a constructivist, qualitative methodology which applied grounded theory analysis techniques. Using purposeful sampling, three pairs of participants (adults with TBI and close others) who had finished a community rehabilitation programme completed separate in-depth interviews which were transcribed verbatim and progressively analysed using a process of constant comparison. Results: A preliminary framework illustrating participants’ experience of a therapeutic alliance was generated, comprising three interconnected themes: being recognised as an individual, working together and feeling personally connected. All participants viewed being able to work together as important in their experience of community rehabilitation and described features that helped and hindered the alliance. Conclusion: These pilot study results demonstrate the importance of the therapeutic alliance to the rehabilitation experience of individuals with TBI and those close to them.

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