Patient and clinician factors associated with uptake of the human papillomavirus (HPV) vaccine among adolescent patients of a primary care network

ObjectiveHuman papillomavirus (HPV) vaccination coverage is low among adolescents in the USA. Identification of factors associated with HPV vaccine initiation (receipt of ≥1 dose) is critical for improving uptake. Our objective was to systematically investigate all eligible factors available in a nationally representative sample of adolescents to identify drivers of HPV vaccine initiation using a novel methodological approach.MethodsWe performed multiple cross-sectional analyses using data from the adolescent component of the National Immunization Surveys (NIS)-Teen between 2014 and 2019. Study participants were parents or caregivers of adolescents aged 13–17 years. Exposure variables measured sociodemographic and geographical characteristics, health conditions and healthcare provision. We tested the association between each factor and HPV vaccine initiation using univariate logistic regression and multivariate logistic regression adjusted for mother’s age, mother’s education level, mother’s marital status, poverty status and adolescent’s sex. We validated findings for each type of analysis within surveys, between surveys (across years 2014–2019) and across several subgroups (age, sex, poverty status and race/ethnicity).ResultsSix factors were replicated in the multivariate analysis. Most replicated factors characterised the role of healthcare providers and healthcare-seeking behaviours. After adjustment, provider HPV recommendation remained the most strongly associated with HPV vaccine initiation (2019 NIS-Teen: OR 13.4, 95% CI 11.3 to 17.3, p<0.001). The variance explained by a full model including replicated factors was 0.39.ConclusionsThis is the first study to explore the association between all available factors in the NIS-Teen and HPV vaccine initiation in a systematic manner. Our study suggests that healthcare-seeking behaviours and interactions with the health system may be drivers of HPV vaccine initiation and warrant further study. Addressing these factors could improve the rate of HPV vaccine initiation among adolescents in the USA.

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Human Papillomavirus Vaccine Course Completion Among Gay and Bisexual Men Who Have Sex With Men From a Time-Limited HPV Vaccination Catch-Up Program in Victoria, Australia

Frontiers in Public Health ◽

10.3389/fpubh.2021.754112 ◽

2021 ◽

Vol 9 ◽

Author(s):

Kay Htaik ◽

Christopher K. Fairley ◽

Marcus Y. Chen ◽

Rebecca Wigan ◽

Elena Rodriguez ◽

...

Keyword(s):

Human Papillomavirus ◽

Hpv Vaccine ◽

Hpv Vaccination ◽

Health Centre ◽

Bisexual Men ◽

Human Papillomavirus Vaccine ◽

Factors Associated ◽

Catch Up ◽

Sex With Men ◽

Hiv Negative

Background: To examine completion of the human papillomavirus (HPV) vaccination 3-dose regimen and factors associated with completion among men who have sex with men (MSM) aged ≤ 26 years participating in a time-limited HPV catch-up vaccination program in Victoria, Australia.Methods: MSM who received their first dose of HPV vaccine at Melbourne Sexual Health Centre in 2017 were followed until October 2019. Vaccination completion was defined as those who received three doses. Multivariable logistic regression was performed to examine factors associated with vaccine completion.Results: 931 of 1,947 (47.8%) eligible men received at least one dose of HPV vaccine, 750 (38.5%) received two and 590 (30.3%) received three doses. The median time to receiving the second and third dose was 2.8 (IQR = 2.1–4.8) and 7.2 (IQR = 6.3–10.7) months, respectively. Gay men had higher odds of receiving three doses compared to bisexual men (aOR = 2.17; 95%CI: 1.16–4.04). Compared with HIV-negative MSM not taking PrEP, HIV-positive MSM were more like to complete vaccination (aOR = 3.92, 95%CI: 1.62–9.47) but no difference was found compared to HIV-negative men taking PrEP (aOR = 1.55; 95%CI: 0.95–2.53).Conclusion: Less than one-third of men aged ≤ 26 years completed the three doses of HPV vaccine. Further studies are needed to understand the barriers of men not completing the vaccine.

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Factors Associated With Clinicians’ Communication Among Adolescent Patients About Human Papillomavirus Vaccination

Journal of Adolescent Health ◽

10.1016/j.jadohealth.2015.10.239 ◽

2016 ◽

Vol 58 (2) ◽

pp. S114

Author(s):

Brittany L. Rosen ◽

Charlene Morrow ◽

Lea Widdice ◽

Tanya L.K. Mullins ◽

Jessica A. Kahn

Keyword(s):

Human Papillomavirus ◽

Human Papillomavirus Vaccination ◽

Factors Associated ◽

Adolescent Patients

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Incidence and risk factors associated with chlamydia in men who have sex with men: a cohort analysis of Victorian Primary Care Network for Sentinel Surveillance data

Sexually Transmitted Infections ◽

10.1136/sextrans-2011-050270 ◽

2012 ◽

Vol 88 (5) ◽

pp. 319-324 ◽

Cited By ~ 19

Author(s):

Anna Wilkinson ◽

Carol El-Hayek ◽

Christopher K Fairley ◽

David Leslie ◽

Norm Roth ◽

...

Keyword(s):

Risk Factors ◽

Primary Care ◽

Cohort Analysis ◽

Sentinel Surveillance ◽

Surveillance Data ◽

Care Network ◽

Factors Associated ◽

Sex With Men

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Health Care Provider Attitudes and Barriers Regarding Human Papillomavirus (HPV) Vaccination: Factors Associated With Increasing HPV Vaccine Coverage Before and After an Intervention Program

Open Forum Infectious Diseases ◽

10.1093/ofid/ofw172.581 ◽

2016 ◽

Vol 3 (suppl_1) ◽

Cited By ~ 1

Author(s):

Huong Q. Mclean ◽

Becky Birchmeier ◽

Brian Chow ◽

Elizabeth Vickers ◽

Michael McNeil ◽

...

Keyword(s):

Health Care ◽

Human Papillomavirus ◽

Care Provider ◽

Hpv Vaccine ◽

Intervention Program ◽

Vaccine Coverage ◽

Hpv Vaccination ◽

Provider Attitudes ◽

Factors Associated ◽

Before And After

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HPV/cervical cancer vaccination: parental preferences on age, place and information needs

Journal of Primary Health Care ◽

10.1071/hc10190 ◽

2010 ◽

Vol 2 (3) ◽

pp. 190 ◽

Cited By ~ 4

Author(s):

Sally Rose ◽

Beverley Lawton ◽

Tolotea Lanumata ◽

Merilyn Hibma ◽

Michael Baker

Keyword(s):

Primary Care ◽

Cervical Cancer ◽

Human Papillomavirus ◽

New Zealand ◽

Hpv Vaccine ◽

Information Needs ◽

Vaccine Coverage ◽

Hpv Vaccination ◽

Family Doctor ◽

Parental Preferences

INTRODUCTION: A vaccine against cervical cancer is available in New Zealand through school and primary care for girls aged 1218 years. Factors that might increase or hinder widespread uptake by the target population need to be identified. Aim: To describe parents preferences on where their daughter(s) receive the human papillomavirus (HPV) vaccine, at what age, and their information needs. METHODS: 3123 questionnaires were distributed to parents recruited from 14 schools in 2008, prior to the start of the school-based vaccination programme. Outcome measures were: preferred age and place of vaccination, and information needs of parents and their daughters. Tests for significance were performed to determine whether parental preferences differed by ethnic group (Maori, Pacific, New Zealand European and Other). RESULTS: A 25% response rate was achieved (769/3123). Receipt of the HPV vaccine in a clinic setting was preferred by 40% of parents; 25% preferred vaccination at school. Fifty percent preferred vaccination to occur at age 13 or older; 28% thought ages 10, 11 or 12 appropriate. One in three parents wanted more information and 65% said they would seek information from their family doctor before deciding on the vaccine for their daughter(s). DISCUSSION: We suggest that a programme delivered jointly in primary care and school settings, that is appropriately resourced for follow-up and information-sharing, would increase vaccine coverage. The rationale for vaccination at age 12 needs to be made clear to parents and evidence-based information needs to be delivered appropriately to parents and girls. KEYWORDS: Human papillomavirus (HPV); vaccination; cervical cancer; survey; ethnicity

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