scholarly journals Genome-wide identification and characterization of long non-coding RNAs in MDCK cell lines with high and low tumorigenicities

Genomics ◽  
2020 ◽  
Vol 112 (2) ◽  
pp. 1077-1086
Author(s):  
Zilin Qiao ◽  
Di Yang ◽  
Lixia Liu ◽  
Zhenbin Liu ◽  
Jiamin Wang ◽  
...  
Keyword(s):  
Cell Lines ◽  
Mdck Cell ◽  
Genome Wide ◽  
Non Coding Rnas ◽  
Identification And Characterization

scholarly journals Genome-Wide Identification and Characterization of Long Non-Coding RNAs in Peanut

Genes ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 536 ◽  
Author(s):  
Xiaobo Zhao ◽  
Liming Gan ◽  
Caixia Yan ◽  
Chunjuan Li ◽  
Quanxi Sun ◽  
...  
Keyword(s):  
Large Scale ◽  
Target Genes ◽  
Sequencing Data ◽  
Regulatory Processes ◽  
Genome Wide ◽  
Non Coding Rnas ◽  
Identification And Characterization ◽  
Lower Expression ◽  
Weighted Correlation

Long non-coding RNAs (lncRNAs) are involved in various regulatory processes although they do not encode protein. Presently, there is little information regarding the identification of lncRNAs in peanut (Arachis hypogaea Linn.). In this study, 50,873 lncRNAs of peanut were identified from large-scale published RNA sequencing data that belonged to 124 samples involving 15 different tissues. The average lengths of lncRNA and mRNA were 4335 bp and 954 bp, respectively. Compared to the mRNAs, the lncRNAs were shorter, with fewer exons and lower expression levels. The 4713 co-expression lncRNAs (expressed in all samples) were used to construct co-expression networks by using the weighted correlation network analysis (WGCNA). LncRNAs correlating with the growth and development of different peanut tissues were obtained, and target genes for 386 hub lncRNAs of all lncRNAs co-expressions were predicted. Taken together, these findings can provide a comprehensive identification of lncRNAs in peanut.

scholarly journals Genome-wide identification and characterization of long non-coding RNAs responsive to Dickeya zeae in rice

RSC Advances ◽  
2018 ◽  
Vol 8 (60) ◽  
pp. 34408-34417 ◽  
Author(s):  
Wen Qi Li ◽  
Yu Lin Jia ◽  
Feng Quan Liu ◽  
Fang Quan Wang ◽  
Fang Jun Fan ◽  
...  
Keyword(s):  
Stress Responses ◽  
Critical Role ◽  
Non Coding Rna ◽  
Genome Wide ◽  
Epigenetic Regulator ◽  
Non Coding Rnas ◽  
Growth Development ◽  
Long Non Coding Rna ◽  
Identification And Characterization

Plant long non-coding RNA (lncRNA) is a type of newly emerging epigenetic regulator playing a critical role in plant growth, development, and biotic stress responses.

Genome-wide identification and characterization of long non-coding RNAs during differentiation of visceral preadipocytes in rabbit

2019 ◽  
Vol 20 (3) ◽  
pp. 409-419 ◽  
Author(s):  
Kun Du ◽  
Guo-Ze Wang ◽  
An-yong Ren ◽  
Ming-cheng Cai ◽  
Gang Luo ◽  
...  
Keyword(s):  
Genome Wide ◽  
Non Coding Rnas ◽  
Identification And Characterization

scholarly journals Genome-wide identification and characterization of lncRNAs responding to iron deficiency in Oryza sativa

2020 ◽  
Author(s):  
Shoudong Wang ◽  
Shuo Sun ◽  
Huixia Shou
Keyword(s):  
Chlorophyll Biosynthesis ◽  
Vital Role ◽  
Fe Deficiency ◽  
Systematic Screening ◽  
Cellular Processes ◽  
Yield And Quality ◽  
Genome Wide ◽  
Non Coding Rnas ◽  
Identification And Characterization

Abstract Background: Iron (Fe) plays a vital role in various cellular processes in plants, including chlorophyll biosynthesis, photosynthesis and respiration. Fe deficiency directly affects crop growth and development, ultimately resulting in reduced crop yield and quality. Long non-coding RNAs (lncRNAs) have recently been demonstrated to play critical regulatory roles in a multitude of pathways across numerous species. However, systematic screening of lncRNAs responding to Fe deficiency in plants has not been reported. In this work, genome-wide identification and characterization of lncRNAs responsive to Fe deficiency were performed by strand-specific RNA sequencing in rice. Results: In total, 6477 lncRNAs were identified. In Fe-deficient conditions, 47 lncRNAs were up-regulated and 33 lncRNAs were down-regulated in shoots, while 89 lncRNAs were up-regulated and 32 lncRNAs were down-regulated in roots compared to normal conditions. The lncRNAs that were differentially expressed under Fe-sufficient and -deficient conditions appear to be clustered in the genome. Among five monocotyledon species, 88 lncRNAs were conserved, but only 3 lncRNAs responded to Fe deficiency in shoots. Two lncRNAs were identified as putative target mimics of miRNAs that respond to Fe deficiency. Conclusions: Our results provide evidence that lncRNAs are involved in Fe-deficiency signaling pathway in plants, providing a new pathway for further investigation into Fe-regulatory and response mechanisms.

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