The protein kinase 60S is a free catalytic CK2α′ subunit and forms an inactive complex with superoxide dismutase SOD1

2003 ◽  
Vol 307 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Olga Abramczyk ◽  
Piotr Zień ◽  
Rafał Zieliński ◽  
Marek Pilecki ◽  
Ulf Hellman ◽  
...  
FEBS Letters ◽  
1999 ◽  
Vol 462 (3) ◽  
pp. 353-357 ◽  
Author(s):  
Barbara Guerra ◽  
Stefan Siemer ◽  
Brigitte Boldyreff ◽  
Olaf-Georg Issinger

2011 ◽  
Vol 39 (2) ◽  
pp. 77 ◽  
Author(s):  
Atefeh PAYEZ ◽  
Faezeh GHANATI ◽  
Seyed Mahdi SEYEDI

It has been shown that Aluminum (Al) toxicity results in over-production of reactive oxygen species (ROS). Despite the fact that ROS can induce MAPK activation, no direct genetic evidence has linked ROS-induced MAPK activation with Al toxicity. The effect of Al on the activation of antioxidant systems in connection with the expression of salicylate-induced protein kinase (SIPK), was examined in tobacco cells. Suspension-cultured tobacco cells (Nicotiana tabacum L. cv. ‘Barley 21’) were treated with or without 80 μM Al. Certain parameters related to antioxidant activity were measured. A MAPKK inhibitor (PD98059) was also applied together with or without Al treatments and semi quantitative RT-PCR was applied to show the expression level of the SIPK gene. Treatment with Al rapidly increased the radical scavenging capacity of cells, catalase and superoxide dismutase activities, and expression of the SIPK gene, as compared to the control cells. In the presence of Al + PD98059, a decrease in catalase and superoxide dismutase activities was observed, compared to those cells which were treated only with Al. These results suggested that a short treatment with Al induced the activity of certain antioxidant enzymes in tobacco cells and that this response was mediated by a MAPK signal transduction pathway.


Cytokine ◽  
1995 ◽  
Vol 7 (6) ◽  
pp. 517-525 ◽  
Author(s):  
Joseph A. Prezioso ◽  
Jue Wang ◽  
Misson Kim ◽  
Lisa Duty ◽  
David J. Tweardy ◽  
...  

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