Phosphorylation and chromatin mechanics: the central importance of substrate conformation in determining the patterns of HL-60 nuclear phosphorylation

With the present paper I study and translate a discourse in the Ekottarika-?gama preserved in Chinese of which no parallel in other discourse collections is known. This situation relates to the wider issue of what significance to accord to the absence of parallels from the viewpoint of the early Buddhist oral transmission. The main topic of the discourse itself is perception of impermanence, which is of central importance in the early Buddhist scheme of the path for cultivating liberating insight. A description of the results of such practice in this Ekottarika-?gama discourse has a somewhat ambivalent formulation that suggests a possible relation to the notion of rebirth in the Pure Abodes, suddh?v?sa. This notion, attested in a P?li discourse, in turn might have provided a precedent for the aspiration, prominent in later Buddhist traditions, to be reborn in the Pure Land.

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Christianity in the Twentieth Century

10.23943/princeton/9780691196848.001.0001 ◽

2019 ◽

Author(s):

Brian Stanley

Keyword(s):

Latin America ◽

Racial Identity ◽

Sub Saharan Africa ◽

Central Importance ◽

Regional Survey ◽

History Of Christianity ◽

The World ◽

History Of ◽

Sub Saharan ◽

Different Parts

This book charts the transformation of one of the world's great religions during an age marked by world wars, genocide, nationalism, decolonization, and powerful ideological currents, many of them hostile to Christianity. The book traces how Christianity evolved from a religion defined by the culture and politics of Europe to the expanding polycentric and multicultural faith it is today—one whose growing popular support is strongest in sub-Saharan Africa, Latin America, China, and other parts of Asia. The book sheds critical light on themes of central importance for understanding the global contours of modern Christianity, illustrating each one with contrasting case studies, usually taken from different parts of the world. Unlike other books on world Christianity, this one is not a regional survey or chronological narrative, nor does it focus on theology or ecclesiastical institutions. The book provides a history of Christianity as a popular faith experienced and lived by its adherents, telling a compelling and multifaceted story of Christendom's fortunes in Europe, North America, and across the rest of the globe. It demonstrates how Christianity has had less to fear from the onslaughts of secularism than from the readiness of Christians themselves to accommodate their faith to ideologies that privilege racial identity or radical individualism.

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Physician Reentry into Clinical Practice: Regulatory Challenges

Journal of Medical Regulation ◽

10.30770/2572-1852-97.1.10 ◽

2011 ◽

Vol 97 (1) ◽

pp. 10-15 ◽

Cited By ~ 3

Author(s):

Gretchen P. Kenagy ◽

Barbara S. Schneidman ◽

Barbara Barzansky ◽

Claudette E. Dalton ◽

Carl A. Sirio ◽

...

Keyword(s):

Clinical Practice ◽

Empirical Studies ◽

Clinical Activity ◽

Central Importance ◽

Regulatory Policies ◽

Physician Competence ◽

Leave Of Absence ◽

Increasing Demand ◽

State Medical Boards ◽

Regulatory Challenges

ABSTRACT Physician reentry to clinical practice is fast becoming recognized as an issue of central importance in discussions about the physician workforce. While there are few empirical studies, existing data show that increasing numbers of physicians take a leave of absence from practice at some point during their careers; this trend is expected to continue. The process of returning to clinical practice is coming under scrutiny due to the public's increasing demand for transparency regarding physician competence. Criteria for medical licensure often do not include an expectation of ongoing clinical activity. Physicians who maintain a license but do not practice for a period of time, therefore, may be reentering the workforce with unknown competency to practice. This paper: (1) presents survey data on current physician reentry policies of state medical boards; (2) discusses the findings from the survey within the context of regulatory challenges that impact physician-reentry; and (3) offers recommendations to facilitate the development of comprehensive, coordinated regulatory policies on physician reentry.

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The Birth of the Prophet Muhammad

American Journal of Islam and Society ◽

10.35632/ajis.v26i1.1415 ◽

2009 ◽

Vol 26 (1) ◽

pp. 97-99

Author(s):

Frederick S. Colby

Keyword(s):

Twentieth Century ◽

Middle Eastern ◽

Formative Period ◽

Central Importance ◽

Islamic Studies ◽

Critical Scholarship ◽

History Of ◽

Late Twentieth ◽

Modern Era ◽

Late Twentieth Century

Despite the central importance of festival and devotional piety to premodernMuslims, book-length studies in this field have been relatively rare.Katz’s work, The Birth of the Prophet Muhammad, represents a tour-deforceof critical scholarship that advances the field significantly both throughits engagement with textual sources from the formative period to the presentand through its judicious use of theoretical tools to analyze this material. Asits title suggests, the work strives to explore how Muslims have alternativelypromoted and contested the commemoration of the Prophet’s birth atdifferent points in history, with a particular emphasis on how the devotionalistapproach, which was prominent in the pre-modern era, fell out of favoramong Middle Eastern Sunnis in the late twentieth century. Aimed primarilyat specialists in Middle Eastern and Islamic studies, especially scholarsof history, law, and religion, this work is recommended to anyone interestedin the history of Muslim ritual, the history of devotion to the Prophet, andthe interplay between normative and non-normative forms ofMuslim beliefand practice ...

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How Should We Educate Students Whose Cultures Frown upon Rational Disputation?

10.1093/oso/9780190682675.003.0017 ◽

2017 ◽

Author(s):

Harvey Siegel

Keyword(s):

Decision Making ◽

Critical Thinking ◽

Public Education ◽

Cultural Diversity ◽

Cultural Differences ◽

Democratic Participation ◽

Central Importance ◽

Full Participation ◽

Rational Argumentation

`How should public education in democratic states deal with the cultural diversity brought about by contemporary globalization? My suggestion is that key to democratic public education is the obligation to foster in students the skills and abilities, and attitudes and dispositions, needed to participate fully in democratic decision-making. Of central importance are the abilities and dispositions required for critical thinking and rational argumentation: evaluating arguments of others, constructing arguments of one’s own that might rationally persuade one’s fellow citizens, etc. Without these abilities and dispositions, full participation in democratic decision-making is impossible. But fostering them is problematic when students are members of cultures in which argumentation is frowned upon. In this paper I address this tension, and argue that while respecting cultural differences is of the first importance, in democracies it cannot override the requirements of democracy itself. When these two clash, the requirements of democratic participation must take precedence.

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The Background II

10.1093/oso/9780198747260.003.0003 ◽

2017 ◽

Author(s):

Edmund Stewart

Keyword(s):

Early Period ◽

Fifth Century ◽

Central Importance ◽

Greek Culture

Chapter 2 demonstrates the central importance of travel to Greek culture. By the fifth century, a network of festivals and sanctuaries, where Greeks of all description could gather, perform, and exchange goods and ideas, was already in existence. Moreover, from an early period travel was seen as an essential part of the work of the poet. This is because poets were professionals who wished to display their skills and abilities before as wide an audience as possible. In many cases, they may also have wished to exploit wider opportunities for enrichment and employment than those available in their home cities. As such, though Greek poets come from many cities, their poetry does not belong exclusively to any one region or locality.

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Women, Power, and Families in Early Modern North America

10.1093/oxfordhb/9780190222628.013.1 ◽

2018 ◽

Author(s):

Sarah M. S. Pearsall

Keyword(s):

Native American ◽

North America ◽

Early Modern ◽

Early Modern Period ◽

The United States ◽

Central Feature ◽

Colonial Power ◽

Central Importance ◽

Sources Of Authority ◽

Effects Of War

The early modern period, spanning 1500 to 1800, was a vital one for what became the United States, and families were critical to the colonies that underpinned it. Households determined lines of belonging and governance; they gave status and formed a central source of power for both women and men. They also functioned symbolically: creating metaphors for authority (father-king) as well as actual sources of authority. Colonialism, or the imposition of foreign governing regimes, also shaped families and intimacies. The regulation of domestic life was a central feature of colonial power, even as individual families, both settler and indigenous, breached rules that authorities sought to impose. This chapter considers the importance of lineage and households, as well as the effects of war, epidemics, and slavery. It traces a range of households, Native American, African, and Euro-American, to argue for the central importance of families in shaping colonial North America.

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‘You see the empty bed which means it’s either a transplant or a death’: a qualitative study exploring the impact of death in the haemodialysis community

BMJ Open ◽

10.1136/bmjopen-2020-046537 ◽

2021 ◽

Vol 11 (6) ◽

pp. e046537

Author(s):

Sheera Sutherland ◽

Kirsty E Durley ◽

Kirsty Gillies ◽

Margaret Glogowska ◽

Daniel S Lasserson ◽

...

Keyword(s):

Qualitative Study ◽

Clinical Setting ◽

Support Services ◽

Research Team ◽

Central Importance ◽

Semistructured Interviews ◽

Age Range ◽

The Impact ◽

Community Patients

ObjectiveTo explore the impact of the death of a patient in the haemodialysis unit on fellow patients.MethodsWe interviewed patients on dialysis in a tertiary dialysis centre using semistructured interviews. We purposively sampled patients who had experienced the death of a fellow patient. After interviews were transcribed, they were thematically analysed by independent members of the research team using inductive analysis. Input from the team during analysis ensured the rigour and quality of the findings.Results10 participants completed the interviews (6 females and 4 males with an age range of 42–88 years). The four core themes that emerged from the interviews included: (1) patients’ relationship to haemodialysis, (2) how patients define the haemodialysis community, (3) patients’ views on death and bereavement and (4) patients’ expectations around death in the dialysis community. Patients noticed avoidance behaviour by staff in relation to discussing death in the unit and would prefer a culture of open acknowledgement.ConclusionStaff acknowledgement of death is of central importance to patients on haemodialysis who feel that the staff are part of their community. This should guide the development of appropriate bereavement support services and a framework that promotes the provision of guidance for staff and patients in this unique clinical setting. However, the authors acknowledge the homogenous sample recruited in a single setting may limit the transferability of the study. Further work is needed to understand diverse patient and nurse experiences and perceptions when sharing the knowledge of a patient’s death and how they react to loss.

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The Denial of the Right of Return as a Rome Statute Crime

Journal of International Criminal Justice ◽

10.1093/jicj/mqaa053 ◽

2020 ◽

Author(s):

Micheal G Kearney

Keyword(s):

International Law ◽

International Criminal Court ◽

Rome Statute ◽

Final Section ◽

International Criminal ◽

Trial Chamber ◽

Criminal Court ◽

Central Importance ◽

Right Of Return ◽

The Right

Abstract In 2018, Pre-Trial Chamber I of the International Criminal Court (ICC) held that conduct preventing the return of members of the Rohingya people to Myanmar could fall within Article 7(1)(k) of the Statute, on the grounds that denial of the right of return constitutes a crime against humanity. No international tribunal has prosecuted this conduct as a discrete violation, but given the significance of the right of return to Palestinians, it can be expected that such an offence would be of central importance should the ICC investigate the situation in Palestine. This comment will review the recognition of this crime against humanity during the process prompted by the Prosecutor’s 2018 Request for a ruling as to the Court’s jurisdiction over trans-boundary crimes in Bangladesh/Myanmar. It will consider the basis for the right of return in general international law, with a specific focus on the Palestinian right of return. The final section will review the elements of the denial of right of return as a crime against humanity, as proposed by the Office of the Prosecutor in its 2019 Request for Authorization of an investigation in Bangladesh/Myanmar.

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ARE MIGRANT STUDENTS CLOSING THE GAP?

Studies in Second Language Acquisition ◽

10.1017/s0272263120000583 ◽

2021 ◽

pp. 1-25

Author(s):

Nicole Marx ◽

Christian Gill ◽

Tim Brosowski

Keyword(s):

Grade Level ◽

Reading Skills ◽

Ad Hoc ◽

Immigrant Students ◽

Central Importance ◽

Migrant Students ◽

Data Points ◽

Closing The Gap ◽

Reading Subskills ◽

Mainstream Students

Abstract Since 2015, increased numbers of newly immigrated schoolchildren in Europe have resulted in divergent, often ad hoc measures to provide for their education. Because the basis of classroom learning is information found in written texts, the development of grade-level reading skills is of central importance. However, little is known about immigrant students’ reading skills at and following transition, and no data is available for Germany, where the study was conducted. We report the results of a longitudinal study in which migrant students’ (N = 136) reading subskills after transition into mainstream were investigated at three points over the course of 2 years and compared to cohort performance (N = 517) in grades 7 through 9. Results showed that immigrant students performed significantly below mainstream students on all measures for all data points, with little evidence that they are beginning to close the gap even after several years in mainstream.

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