scholarly journals A.229 Neostigmine methylsulphate as an additive in spinal and extradural anaesthesia: comparative evaluation of analgesia duration and some side effects

1996 ◽  
Vol 76 ◽  
pp. 72-73
Author(s):  
Ch. Minovsky ◽  
S. Popova ◽  
A. Milinich ◽  
I. Apostolov
Keyword(s):  
Side Effects ◽  
Comparative Evaluation

scholarly journals Comparative evaluation of clinical effectivity and side effects of two different parenteral agents used in the treatment of osteoporosis

2014 ◽  
Vol 1 (1) ◽  
pp. 1 ◽  
Author(s):  
Ahmet Aslan ◽  
Ahmet Özmeriç ◽  
Ökkeş Bilal ◽  
Fatih Doğar ◽  
Zübeyde Özkaya ◽  
...  
Keyword(s):  
Side Effects ◽  
Comparative Evaluation ◽  
Treatment Of Osteoporosis

scholarly journals Tacrolimus versus Cyclosporine- Comparative Evaluation as First line drug in Vernal keratoconjuctivitis

2018 ◽  
Vol 9 (2) ◽  
pp. 128-135 ◽  
Author(s):  
Rashmi Kumari ◽  
Bhawesh Chandra Saha ◽  
Bibhuti Prasanna Sinha ◽  
Nilesh Mohan
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Comparative Study ◽  
Comparative Evaluation ◽  
Subjective Symptom ◽  
First Line ◽  
Symptom Scores ◽  
Double Blinded ◽  
Line Drug ◽  
Ocular Sign

Introduction: The aim of the study was to evaluate and compare the efficacy, side effects and recurrence rate of vernal kerato conjunctivitis (VKC) with 0.03% tacrolimus and 0.05% cyclosporin.Material and method: A prospective randomised double blinded comparative study was conducted at a tertiary eye center. 46 Patients of VKC between March 2015- August 2015 were randomly divided into two groups and treated for 6weeks with either Tacrolimus(0.03%) eye ointment BD or Cyclosporine (0.05%) eyedrops QID.The main outcome measures were scoring and comparison of Total subjective symptom scores (TSSS) and Total objective ocular sign scores (TOSS) within and between the Groups at each follow up.Thirty two patients, sixteen from each group, with comparable baseline characters were analysed.Results: With treatment both TSSS and TOSS decreased consistently in both groups without any adverse effects but an increase in scores was noticed within two weeks after drug withdrawal.Conclusion: Both drugs are equally effective and safe in VKC but with short lasting effect.

scholarly journals DEXMEDETOMIDINE VERSUS FENTANYL IN LOWER LIMB ORTHOPEDIC SURGERIES: A COMPARATIVE EVALUATION

2021 ◽  
Vol 5 (9) ◽  
Author(s):  
Sukumar Misra
Keyword(s):  
Side Effects ◽  
Epidural Analgesia ◽  
Lower Limb ◽  
Local Anesthetics ◽  
Comparative Evaluation ◽  
Motor Block ◽  
Sensory Block ◽  
Comparative Assessment ◽  
Epidural Fentanyl ◽  
Viable Option

Abstract: opioids and local anesthetics have been the traditional choice in epidural analgesia. However opioids suffer from the issue of side effects and res piratory depression. The use of newer agent like dexmedetomidine is a viable option. The present study was formulated to provide a comparative assessment of whether fentanyl or dexmedetomidine is a better adjuvant for lower limb surgeries in which epidural route is used. The study included a pool of 30 subjects who were divided in two equal groups and administered fentanyl or dexmedetomidine. The results displayed a shorter duration of sensory block and motor block in dexmedetomidine group as compared to fentanyl. The overall efficacy of dexmedetomidine was better in the present study. Keywords: analgesia, dexmedetomidine, epidural, fentanyl

scholarly journals Comparative evaluation of fissurectomy versus lateral internal sphincterotomy in the treatment of chronic anal fissure

2018 ◽  
Vol 5 (4) ◽  
pp. 1407
Author(s):  
A. R. Bansal ◽  
Pradeep Yadav ◽  
Suvendu Jena ◽  
Sanjeev Kumar
Keyword(s):  
Side Effects ◽  
Pain Relief ◽  
Anal Fissure ◽  
Comparative Evaluation ◽  
Chronic Anal Fissure ◽  
Symptomatic Relief ◽  
Age Groups ◽  
Complete Healing ◽  
Lateral Internal Sphincterotomy ◽  
Internal Sphincterotomy

Background: Anal fissure is a common anorectal condition that affecting all age groups, but it is seen in young and healthy adults with equal incidence across both the sexes. The objective of this study was to evaluate and prospectively compare fissurectomy versus lateral internal sphincterotomy in the treatment of chronic anal fissure in terms of symptomatic relief, healing, recurrence and incontinence, if any.Methods: 50 patients with chronic anal fissure were alternately divided in two groups. In one group fissurectomy was done and in another group, patients underwent lateral internal sphincterotomy and comparative evaluation was done.Results: Complete healing was observed in 92% patients in fissurectomy group and 96% patients in lateral internal sphincterotomy group at the end of 6 weeks. Fissurectomy group patients reported early cut through of sutures and infection whereas in lateral internal sphincterotomy group two patients developed perianal hematoma at 3 months of follow up.Conclusions: While considering surgical management for treating chronic anal fissure, fissurectomy is comparable to lateral internal sphincterotomy in terms of symptomatic pain relief, healing rates with minimal side effects and low recurrence.

Efficacy of Iron Therapy: A Comparative Evaluation of Four Iron Preparations Administered to Anaemic Pregnant Women

1985 ◽  
Vol 13 (1) ◽  
pp. 1-11 ◽  
Author(s):  
F Fochi ◽  
M Ciampini ◽  
G Ceccarelli
Keyword(s):  
Side Effects ◽  
Pregnant Women ◽  
Folinic Acid ◽  
Comparative Evaluation ◽  
Clinical Investigation ◽  
Ferrous Sulphate ◽  
Similar Efficacy ◽  
Iron Therapy ◽  
Haematological Parameters ◽  
Acid Complex

The authors conducted a clinical investigation on sixty-nine pregnant women, anaemic and non-anaemic, the purpose being to assess the effect of 50 days treatment with four different medicinal iron preparations, namely, ferrous sulphate, iron chondroitinsulfuric acid complex, and ferritin alone or associated with folinic acid and cobamamide, on various haematological parameters (Hb, RCC, Ht, CV, Iron, and Transferrin IBC). The four products demonstrated a similar efficacy in maintaining anaemic conditions under control; moreover, the results confirmed our hypothesis of the absorption of iron ferritin. While three products were well tolerated, ferrous sulphate induced, in some cases, side-effects.

Gastric Ulcers Produced by Cisplatin

1981 ◽  
Vol 39 ◽  
pp. 582-583
Author(s):  
S.K. Aggarwal ◽  
J. San Antonio
Keyword(s):  
Electron Microscopy ◽  
Single Dose ◽  
Side Effects ◽  
Antitumor Agent ◽  
Gastric Ulcers ◽  
Enzyme Cytochemistry ◽  
Intestinal Toxicity ◽  
Ovarian Cancers ◽  
Inner Surface

Cisplatin (cis-dichlorodiammineplatinum(II)) a potent antitumor agent is now available for the treatment of testicular and ovarian cancers. It is however, not free from its serious side effects including nephrotoxicity, gastro intestinal toxicity, myelosuppression, and ototoxicity. Here we now report that the drug produces peculiar bloating of the stomach in rats and induces acute ulceration.Wistar-derived rats weighing 200-250 g were administered cisplatin(9 mg/kg) ip as a single dose in 0.15 M NaCl. After 3 days the animals were sacrificed by decapitation. The stomachs were removed, the contents analyzed for pepsin and acidity. The inner surface was examined with a dissecting microscope after a moderate stretching for ulcers. Affected areas were fixed and processed for routine electron microscopy and enzyme cytochemistry.The drug treated animals kept on food and water consistently showed bloating and lesions (Fig. 1) with a frequency of 6-70 ulcers in the rumen section of the stomachs.

Effects of cisplatin treatment on the rat neurohypophysis

1986 ◽  
Vol 44 ◽  
pp. 122-123
Author(s):  
J.M. Fadool ◽  
P.J. Boyer ◽  
S.K. Aggarwal
Keyword(s):  
Side Effects ◽  
Urine Output ◽  
Morphological Changes ◽  
Limiting Factor ◽  
Antineoplastic Drugs

Cisplatin (CDDP) is currently one of the most valuable antineoplastic drugs available. However, it has severe toxic side effects of which nephrotoxicity is the major dose limiting factor in its use. It induces morphological changes in the kidney with hampered urine output. The present study is an effort to determine the influence of the drug on the neurohypophysis for any antidiuretic effects on the kidney.

Comparison of In-the-Ear and Over-the-Ear Hearing Aid Fittings

1986 ◽  
Vol 51 (4) ◽  
pp. 362-369 ◽  
Author(s):  
Donna M. Risberg ◽  
Robyn M. Cox
Keyword(s):  
Hearing Aids ◽  
High Frequency ◽  
Comparative Evaluation ◽  
Speech Intelligibility ◽  
Hearing Aid ◽  
Hearing Aid Fitting ◽  
The Difference ◽  
Functional Gain ◽  
The Relationship

A custom in-the-ear (ITE) hearing aid fitting was compared to two over-the-ear (OTE) hearing aid fittings for each of 9 subjects with mild to moderately severe hearing losses. Speech intelligibility via the three instruments was compared using the Speech Intelligibility Rating (SIR) test. The relationship between functional gain and coupler gain was compared for the ITE and the higher rated OTE instruments. The difference in input received at the microphone locations of the two types of hearing aids was measured for 10 different subjects and compared to the functional gain data. It was concluded that (a) for persons with mild to moderately severe hearing losses, appropriately adjusted custom ITE fittings typically yield speech intelligibility that is equal to the better OTE fitting identified in a comparative evaluation; and (b) gain prescriptions for ITE hearing aids should be adjusted to account for the high-frequency emphasis associated with in-the-concha microphone placement.

Sign in / Sign up

Export Citation Format

Share Document