Tu1179 Clinical Characteristics and Risk Factors of Colonic Diverticulosis - Analysis From Japanese Multicenter Prospective Cross-Sectional Study-

Abstract Background The HIV pandemic continues to cause a high burden of morbidity and mortality due to delayed diagnosis. Histoplasmosis is prevalent in Latin America and Colombia, is difficult to diagnose and has a high mortality. Here we determined the clinical characteristics and risk factors of histoplasmosis in people living with HIV (PLWH) in Pereira, Colombia. Materials and methods This was a retrospective cross-sectional study (2014–2019) involving two tertiary medical centers in Pereira, Colombia. People hospitalized with HIV were included. Histoplasma antigen detection was performed in urine samples. Probable histoplasmosis was defined according to European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group/National Institute of Allergy and Infectious Diseases Mycoses Study Group criteria. Results 172 HIV-infected patients were analyzed. Histoplasmosis was confirmed in 29% (n = 50/172) of patients. The logistic regression analysis showed that the risk factors for histoplasmosis were pancytopenia (OR 4.1, 95% CI 1.6–10.3, P = 0.002), < 50 CD4 + cells/μL (OR 3.1, 95% CI 1.3–7.3, P = 0.006) and Aspartate transaminase (AST) levels > 46 IU/L (OR 3.2, 95% CI 1.3–8, P = 0.010). Conclusions Histoplasmosis is highly prevalent in hospitalized patients with HIV in Pereira, Colombia. The clinical findings are nonspecific, but there are some clinical abnormalities that can lead to suspicion of the disease, early diagnosis and prompt treatment. Urine antigen detection is useful for diagnosis, but is not widely available. An algorithmic approach is proposed for low-resource clinical settings.

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Risk factors for long term complications among patients of endocrine clinic in Hospital Penang, Malaysia

Journal of Health Sciences ◽

10.17532/jhsci.2012.47 ◽

2012 ◽

Vol 2 (2) ◽

pp. 104-117

Author(s):

Wasif Gillani ◽

Syed Sulaiman ◽

Shameni Sundram ◽

Maisharah Sheikh Ghadzi ◽

Noor Haroon ◽

...

Keyword(s):

Risk Factors ◽

Clinical Characteristics ◽

Cross Sectional Study ◽

Drop Out ◽

Sectional Study ◽

Cross Sectional ◽

Sociodemographic Differences ◽

Study Population ◽

Collection Form

Introduction: The prevalence of diabetes is on the increase and an estimated 239 million people worldwide are expected to have the condition by the year 2020 (1). Diabetes mellitus (DM) represents a serious healthcare challenge. The aim of the study was to evaluate the patient clinical characteristics and risk factors for long term complications in the endocrine clinic of Hospital Penang, Malaysia.Methods: Descriptive Prospective cross-sectional study design was chosen. To achieve a power of 0.7 with alpha set at 0.05, 186 subjects were required for the study but researcher increase the sample to 297 in caseof drop out. Self-developed data collection form was used to collect the patient information.Results: 297 (100%) patients were enrolled from OPD diabetic clinic of Hospital Palau Pinang. Among the sample 150 (50.5%) were males and rest 147 (49.5%) females. Malay males mean weight at the time of diagnosis significantly higher (p<0.001,) as compared to other ethnics, same results found among Malay females (p<0.001). Findings suggested increased number of risk factors among the study population. Finding alsoshowed that hypertension found among all the classes of diagnosis. Signifi cant variable are diagnosis class and medication consideration.Conclusion of the study suggested that majority of patients are at high risk of long-term complications and comorbidies. It has been found that increased rate of risk factors have been found among the study population and non-significant to sociodemographic differences.

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PRRSV: Risikofaktoren und Herdenprävalenz in Deutschland

Tierärztliche Praxis Ausgabe G Großtiere / Nutztiere ◽

10.1055/a-0867-8990 ◽

2019 ◽

Vol 47 (02) ◽

pp. 132-132

Author(s):

Sebastian Ganz

Keyword(s):

Risk Factors ◽

Cross Sectional Study ◽

Respiratory Syndrome Virus ◽

Sectional Study ◽

Cross Sectional ◽

Klinische Symptome

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.

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