Brain ischemia/reperfusion-triggered protein carbonyl group formation in the brain and heart

2002 ◽  
Vol 34 (6) ◽  
pp. A88
Author(s):  
Olga Ondrejičková ◽  
Svorad Štolc ◽  
L'ubica Horáková ◽  
Attila Ziegelhöffer
Keyword(s):  
Carbonyl Group ◽  
Brain Ischemia ◽  
Ischemia Reperfusion ◽  
Group Formation ◽  
Protein Carbonyl ◽  
The Brain ◽  
Protein Carbonyl Group

Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution

2017 ◽  
Vol 64 ◽  
pp. 103-115 ◽  
Author(s):  
Laura García-Pupo ◽  
Jeney Ramírez Sánchez ◽  
Dariusz Ratman ◽  
Claudina Pérez-Novo ◽  
Ken Declerck ◽  
...  
Keyword(s):  
Brain Ischemia ◽  
Ischemia Reperfusion ◽  
Neuroprotective Effects ◽  
The Brain

scholarly journals The Relationship between the Antioxidant System and Proline Metabolism in the Leaves of Cucumber Plants Acclimated to Salt Stress

Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 609
Author(s):  
Marcin Naliwajski ◽  
Maria Skłodowska
Keyword(s):  
Salt Stress ◽  
Carbonyl Group ◽  
Antioxidant System ◽  
Thiobarbituric Acid ◽  
Nacl Stress ◽  
Protein Carbonyl ◽  
Enzymatic Antioxidants ◽  
Proline Metabolism ◽  
Proline Dehydrogenase ◽  
Protein Carbonyl Group

The study examines the effect of acclimation on the antioxidant system and proline metabolism in cucumber leaves subjected to 100 and 150 NaCl stress. The levels of protein carbonyl group, thiobarbituric acid reactive substances, α-tocopherol, and activity of ascorbate and glutathione peroxidases, catalase, glutathione S-transferase, pyrroline-5-carboxylate: synthetase and reductase as well as proline dehydrogenase were determined after 24 and 72 h periods of salt stress in the acclimated and non-acclimated plants. Although both groups of plants showed high α-tocopherol levels, in acclimated plants was observed higher constitutive concentration of these compounds as well as after salt treatment. Furthermore, the activity of enzymatic antioxidants grew in response to salt stress, mainly in the acclimated plants. In the acclimated plants, protein carbonyl group levels collapsed on a constitutive level and in response to salt stress. Although both groups of plants showed a decrease in proline dehydrogenase activity, they differed with regard to the range and time. Differences in response to salt stress between the acclimated and non-acclimated plants may suggest a relationship between increased tolerance in acclimated plants and raised activity of antioxidant enzymes, high-level of α-tocopherol as well, as decrease enzyme activity incorporates in proline catabolism.

scholarly journals Effects of Ramadan Fasting on Serum Amyloid A and Protein Carbonyl Group Levels in Patients With Cardiovascular Diseases

2015 ◽  
Vol 7 (2) ◽  
pp. 55-59 ◽  
Author(s):  
Hami Asadi ◽  
Ali Akbar Abolfathi ◽  
Reza Badalzadeh ◽  
Maryam Majidinia ◽  
Alireza Yaghoubi ◽  
...  
Keyword(s):  
Cardiovascular Diseases ◽  
Carbonyl Group ◽  
Serum Amyloid A ◽  
Protein Carbonyl ◽  
Serum Amyloid ◽  
Ramadan Fasting ◽  
Amyloid A ◽  
Protein Carbonyl Group

scholarly journals The effect of melaxen administration on the tissue oxidative status in rats with brain ischemia/reperfusion

2016 ◽  
Vol 62 (5) ◽  
pp. 561-565 ◽  
Author(s):  
T.N. Popova ◽  
O.A. Safonova ◽  
A.O. Stolyarova
Keyword(s):  
Oxidative Stress ◽  
Brain Ischemia ◽  
Ischemia Reperfusion ◽  
Oxidative Status ◽  
Total Antioxidant Activity ◽  
Aconitate Hydratase ◽  
Protective Properties ◽  
Total Antioxidant ◽  
Radical Processes ◽  
The Brain

Melaxen administration to rats with brain ischemia/reperfusion was accompanied by a decrease of the lactate level (an organ ischemia marker), biochemiluminescence parameters characterizing the intensity of free radical processes and total antioxidant activity, the content of lipid peroxidation products, activity of superoxide dismutase and catalase, as compared with the values determined in rats with induced brain ischemia/reperfusion. Activity of aconitate hydratase, a sensitive target of free radicals action, and the citrate level in the brain and blood serum of melaxen-treated animals changed towards control values of intact animals. It is assumed that the effect of melaxen is associated with implementation of the antioxidant and protective properties of melatonin, the melaxen constituent, under conditions of post-ischemic reperfusion injury, accompanied by oxidative stress development.

scholarly journals The Effect of Hemp Cake (Cannabis sativa L.) on the Characteristics of Meatballs Stored in Refrigerated Conditions

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5284
Author(s):  
Klaudia Kotecka-Majchrzak ◽  
Natalia Kasałka-Czarna ◽  
Anita Spychaj ◽  
Beata Mikołajczak ◽  
Magdalena Montowska
Keyword(s):  
Dry Matter ◽  
Cannabis Sativa ◽  
Group Formation ◽  
Meat Products ◽  
Textural Properties ◽  
Inhibitory Effect ◽  
Protein Carbonyl ◽  
Refrigerated Storage ◽  
Tbars Values ◽  
Protein Carbonyl Group

Hemp cake, a by-product of cold pressing oil from hemp seeds, is a nutritious ingredient that could be used for the production of new or reformulated meat products. The aim of this study was to determine the influence of inclusion of 0.9%, 2.6%, 4.2%, and 7.4% (w/w) hemp cake (Cannabis sativa L.) on the physicochemical and textural properties, oxidation, and sensory acceptance of cooked and vacuum-packed meatballs during refrigerated storage. The addition of 7.4% hemp cake enhanced the amount of dry matter and reduced the content of water. Lightness (L*) and redness (a*) values reduced significantly with higher levels of hemp supplementation. Regardless of the amount of hemp additive, pH, color parameters did not differ significantly during the 12 days of storage. Hemp cake significantly decreased protein and lipid oxidation: the inhibitory effect of adding 7.4% hemp cake on protein carbonyl group formation and TBARS values reached 11.16% and 36.5%, respectively, after 10 days of storage. Sensory analysis revealed that meatballs prepared with 0.9% and 2.6% hemp cake gained higher overall scores. The results indicate that hemp cake, a material considered mainly as waste, may be destined for food purposes and be an alternative ingredient for the production of sustainable meat products.

Protective effect of resveratrol on formation of membrane protein carbonyls and lipid peroxidation in erythrocytes subjected to oxidative stress

2009 ◽  
Vol 34 (6) ◽  
pp. 1093-1097 ◽  
Author(s):  
Kanti Bhooshan Pandey ◽  
Syed Ibrahim Rizvi
Keyword(s):  
Oxidative Stress ◽  
Carbonyl Group ◽  
Antioxidant Properties ◽  
Protein Carbonyl ◽  
Protein Carbonyls ◽  
Beneficial Effects ◽  
Group Content ◽  
Tert Butylhydroperoxide ◽  
Protein Carbonyl Group

Many of the biological actions of resveratrol have been attributed to its antioxidant properties. In this work, we subjected human erythrocytes to in vitro oxidative stress by incubating them with tert-butylhydroperoxide (t-BHP). This caused a significant increase in the malondialdehyde (MDA) level and the protein carbonyl group content above the basal values. The presence of trans-resveratrol at micromolar concentrations in the incubation medium protected the erythrocytes from t-BHP-induced oxidative stress, as evidenced by the decrease in the MDA level and the protein carbonyl group content. The effect of resveratrol was concentration and time-dependent. Our findings help to explain some of the beneficial effects of resveratrol.

Exploring the Role of Remote Ischemic Preconditioning In Long Term Cognitive Impairment after Global Ischemia-Reperfusion-Induced Vascular Dementia in Mice

2020 ◽  
Author(s):  
Amteshwar Singh Jaggi
Keyword(s):  
Cognitive Impairment ◽  
Cerebral Ischemia ◽  
Vascular Dementia ◽  
Ischemic Preconditioning ◽  
Ischemia Reperfusion ◽  
Remote Ischemic Preconditioning ◽  
Global Cerebral Ischemia ◽  
Cerebral Ischemic ◽  
The Brain

Aim: The aim of the present study is to explore the neuroprotective effects of remote ischemic preconditioning in long term cognitive impairment after global cerebral ischemia induced-vascular dementia in mice. Material and methods: The mice were subjected to global cerebral ischemia by occluding the bilateral common carotid arteries for 12 minutes followed by the 24 hours of the reperfusion. The remote ischemic preconditioning stimulus was delivered in the form of 4 cycles of ischemia/reperfusion for 5 minutes each. The cerebral ischemic injury induced-long term cognitive impairment-related learning and memory alterations was assessed using morris water maze, the motor performances of the animals were evaluated using rota-rod test and neurological severity score. The cerebral infract size of the brain were quantified using triphenyltetrazolium chloride staining. Results: Global cerebral ischemia causes long term memory impairment, decreases motor performances and increases the brain infract size in animals. The delivery of remote ischemic preconditioning stimulus significantly abolished the long-term cognitive impairment and ameliorates the motor performances as well as cerebral infract size in brain. Conclusion: The remote ischemic preconditioning mediates neuro protection against global cerebral ischemic injury induced long-term cognitive impairment.

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