Economic feasibility of a small-scale production plant for entomopathogenic fungi in Nicaragua

2001 ◽  
Vol 20 (7) ◽  
pp. 623-630 ◽  
Author(s):  
Christoph Grimm
1997 ◽  
Vol 129 (S171) ◽  
pp. 101-113 ◽  
Author(s):  
Dan Swanson

AbstractThe net present value (NPV) approach to capital budgeting is used to determine the relative economic feasibility of two production models capable of manufacturing a fungi-based biopesticide in Madagascar. Sales revenues are projected at $10–12 per hectare for 20 000–80 000 ha annually, with recurrent costs estimated in Madagascar and investment costs from IITA (Cotonou, Benin) and Mycotech Corporation (Butte, Montana). These cash flows are discounted by an appropriate interest rate and risk factor, with positive results for both the labour-intensive model and the capital-intensive model under several scenarios. Cost advantages for the two models depend on both technology and scale. The labour-intensive model achieves a higher NPV in a market of 20 000 ha per annum as compared with the capital-intensive model. The capital-intensive model achieves a higher NPV in a market of 80 000 ha (including exports to southern Africa). Both models benefit from scale economies, although this benefit is relatively greater for the capital-intensive model. Consumers of mycopesticides in Madagascar could realize nearly 20% savings under a higher output scenario with a capital-intensive technology, than under a lower output scenario with a labour-intensive technology. Large-scale producers, however, would require nearly four times as much investment capital, and could find it difficult to produce for export from Madagascar. In the absence of a large-scale producer, small-scale production would be appropriate and feasible based on lower investment costs. Malagasy production is also protected from foreign competition because of current phytosanitary regulations.


2020 ◽  
Vol 33 ◽  
pp. 2
Author(s):  
Miguel Ángel Mejía-Ramírez ◽  
Verónica Valadez Rocha ◽  
Carlos Iván Pérez-Rostro

The snail Pomacea patula catemacensis is an endemic mollusk from the southeast Gulf of Mexico, which is commercially exploited and in decline since 2010. This decline is associated with an increasing market demand and illegal capture. We designed a small-scale production system for P. p. catemacensis and determined its financial feasibility for a base scenario. We used information gathered from stakeholders and stochastic modeling to predict the impact of uncertain variables on the economic indicators to assess the financial viability under varying conditions. The small-scale intensive production system, designed to yield 3.9 tons/year of unshelled product, requires an investment of about US $65,000. The production unit was financially assessed using the Modified Internal Return Rate and The Net Present Value of cash flow, considering a 14% discount rate and a 7% reinvestment rate. We obtained a Net Present Value of $67,000 and a Modified Internal Return Rate of 20% for the base scenario, which indicates the viability of the project. A Monte Carlo simulation was run to assess the robustness of the project to variability of three parameters: labor cost, energy cost, and market price; with random and simultaneous variation, resulting in 95% probability of getting a Modified Internal Return Rate larger than the current interest rate (8%) and a low probability (2.8%) to be financially unviable. This production system is worthy of consideration as an option to reduce the fishing pressure on the tegogolo natural populations of the Catemaco Lake while satisfying the market demand.


Author(s):  
ManDjun Lee ◽  
Prashobh Karunakaran ◽  
RahmatAidil Djubair ◽  
Heng Jong Ngu

Author(s):  
Asep Bayu Dani Nandiyanto ◽  
◽  
Dea Bella Dewary Atika Putri ◽  
Yayan Sunarya ◽  
Jarot Raharjo ◽  
...  

Lanthanum nickelate (La2NiO4) is a precursor for producing lanthanum pentanickel (LaNi5) alloys for nickel-metal hydride battery (NiMH; a type of rechargeable battery), which has been developed quite rapidly for many applications, such as Hybrid Electric Vehicles. The purpose of this study was to evaluate the economic feasibility of the production of La2NiO4 with different fuels (i.e., glycine fuel (F-G) and citric acid fuel (F-CA)) using a sol-gel combustion method. Several economic evaluation parameters were analyzed, such as gross profit margin, internal rate of return, payback period, cumulative net present value, and so on. The project was evaluated from the ideal condition to the worst-case conditions, including labor, sales, raw material, utility, as well as external conditions (e.g., tax). The results showed that the production of La2NiO4 is prospective from engineering and economic perspectives. The engineering analysis for both production steps using F-G and F-CA is feasible, and the production can be done even in small-scale production using commercially available apparatus. The economic analysis showed that the process using F-CA is better than that using F-G. From this economic evaluation analysis, the project is profitable and the recovery of the investment is less than seven years for F-G and four years for F-CA. Although this project is feasible to run and profitable, it is not attractive to industrial investors due to the fewer values in some parameters. Thus, since this material is very important to reduce dependence on imports, additional further technologies for improving processes and support from Corporate Social Responsibility (CSR) and government are important for maintaining this project.


2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Bùi Thị Bích Lan

In Vietnam, the construction of hydropower projects has contributed significantly in the cause of industrialization and modernization of the country. The place where hydropower projects are built is mostly inhabited by ethnic minorities - communities that rely primarily on land, a very important source of livelihood security. In the context of the lack of common productive land in resettlement areas, the orientation for agricultural production is to promote indigenous knowledge combined with increasing scientific and technical application; shifting from small-scale production practices to large-scale commodity production. However, the research results of this article show that many obstacles in the transition process are being posed such as limitations on natural resources, traditional production thinking or the suitability and effectiveness of scientific - technical application models. When agricultural production does not ensure food security, a number of implications for people’s lives are increasingly evident, such as poverty, preserving cultural identity, social relations and resource protection. Since then, it has set the role of the State in researching and building appropriate agricultural production models to exploit local strengths and ensure sustainability.


Author(s):  
Hariyadi DM ◽  
Athiyah U ◽  
Hendradi E ◽  
Rosita N ◽  
Erawati T ◽  
...  

The prevention of Diabetic Mellitus (DM) and its complications is the main aim of this study, in addition to the training of lotion foot care application and the development of small scale industry. The research team delivered knowledge in the form of training on Diabetic Mellitus, healthy food, treatment and prevention of complications, and small-scale production of cosmetic products. The aim of this study was to determine the correlation between training on diabetic and lotion foot care application as preventive measures against diabetic complications on the patient's blood glucose levels in the community of residents in Banyuurip Jaya, Surabaya. It was expected from this training that the knowledge of the residents increases and people living with diabetic undergo lifestyle changes and therefore blood sugar levels can be controlled. The parameters measured in this research were blood glucose levels, the anti diabetic drug types consumed, and compliance on diabetics. This study used the data taken from 60 patients with DM over a period of one month. Questionnaires and log books was used to retrieve data and changes in blood glucose levels in diabetic patients. The results showed the demographic data of patients with type 2 diabetic of 85% female and 15% male, with the range of patients aged of 61-70 years of 46.67% and had history of diabetic (90%). The history of drugs consumed by respondents was anti diabetic drugs such as metformin (40%), glimepiride (33.37%) and insulin (6.67%). In addition, the increased knowledge of DM patients after being given the training compared to before training was shown in several questions in the questionnaire. A statistical analysis using t-test analyzed a correlation between training provided in order to enhance understanding of the patient, as well as correlation with blood glucose levels. A paired T-test showed that there was a relationship between the knowledge of trainees before and after training (p less than 0.05). An interesting result was that there was no relationship between blood glucose levels before and after training provided (p> 0.05).


Author(s):  
Murugan Paradesi Chockalingam ◽  
Navaneethakrishnan Palanisamy ◽  
Saji Raveendran Padmavathy ◽  
Edwin Mohan ◽  
Beno Wincy Winsly ◽  
...  

2021 ◽  
Vol 4 ◽  
pp. 100153
Author(s):  
Armel Gougbedji ◽  
Pamphile Agbohessou ◽  
Philippe A. Lalèyè ◽  
Frédéric Francis ◽  
Rudy Caparros Megido

Vaccines ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 3
Author(s):  
Zoltán Kis ◽  
Cleo Kontoravdi ◽  
Robin Shattock ◽  
Nilay Shah

To overcome pandemics, such as COVID-19, vaccines are urgently needed at very high volumes. Here we assess the techno-economic feasibility of producing RNA vaccines for the demand associated with a global vaccination campaign. Production process performance is assessed for three messenger RNA (mRNA) and one self-amplifying RNA (saRNA) vaccines, all currently under clinical development, as well as for a hypothetical next-generation saRNA vaccine. The impact of key process design and operation uncertainties on the performance of the production process was assessed. The RNA vaccine drug substance (DS) production rates, volumes and costs are mostly impacted by the RNA amount per vaccine dose and to a lesser extent by the scale and titre in the production process. The resources, production scale and speed required to meet global demand vary substantially in function of the RNA amount per dose. For lower dose saRNA vaccines, global demand can be met using a production process at a scale of below 10 L bioreactor working volume. Consequently, these small-scale processes require a low amount of resources to set up and operate. RNA DS production can be faster than fill-to-finish into multidose vials; hence the latter may constitute a bottleneck.


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