Osteoid Osteoma of the Terminal Phalanx

1984 ◽  
Vol 9 (2) ◽  
pp. 201-203 ◽  
Author(s):  
Y. NAKATSUCHI ◽  
Y. SUGIMOTO ◽  
M. NAKANO
Keyword(s):  
Nervous System ◽  
Nerve Fibre ◽  
Osteoid Osteoma ◽  
Middle Finger ◽  
Clinical Entity ◽  
Diagnosis And Treatment ◽  
Pathological Examination ◽  
Rare Clinical Entity ◽  
Nerve Fibres ◽  
X Ray

The occurrence of osteoid osteoma in the hand is rare, and the rarest of all locations is the terminal phalanx. An osteoid osteoma of the terminal phalanx of the middle finger in a twenty-four-year old woman is described. This case illustrated the very typical clinical and x-ray features of an osteoid osteoma, which made diagnosis and treatment of this rare clinical entity straightforward. On pathological examination, a bundle of nerve fibres was found in the lesion, an explanation that the pain of this tumour may have been mediated by the nervous system via the nerve fibre.

Aberrant Nerve Fibres in Human Development

Development ◽  
1960 ◽  
Vol 8 (2) ◽  
pp. 119-129
Author(s):  
J. D. Boyd ◽  
A. F. W. Hughes
Keyword(s):  
Nervous System ◽  
Human Development ◽  
Nerve Fibre ◽  
Early Years ◽  
Developmental Studies ◽  
Nerve Fibres ◽  
Ground Plan ◽  
Technical Developments ◽  
Previous Decade ◽  
Ramón Y Cajal

In the early years of this century debate concerning the development of nerve fibres became more intense. During the previous decade, following the developmental studies of His (1883, 1886) and the early embryological studies of Ramon y Cajal (1890), the neurone theory as proclaimed by Waldeyer in 1891 seemed assured of victory; but when, with Apáthy and Bethe, new technical developments diverted attention from the whole neurone to its apparent constituents, the neurofibrillae, the simple concept of the outgrowth of the nerve fibre became enmeshed in complexity. Methods for their impregnation with silver were soon elaborated (Bielschowsky, 1904; Ramon y Cajal, 1903), and Held (1907) affirmed that a network of neurofibrillae preceded the appearance of the definitive nerve process. This claim became associated with the much older views of Hensen (1864, 1876) that protoplasmic strands were the forerunners of the nerve fibres and constituted a ground plan for the later development of the peripheral nervous system.

scholarly journals Oncogenic Osteoblastoma: A Rare Clinical Entity in the PNS Arising from Ethmoidal Sinus

2011 ◽  
Vol 2 (2) ◽  
pp. 101-102
Author(s):  
Champion Venkateshalu Srinivas ◽  
Stanley Jhon ◽  
N Kailash ◽  
L Savithri ◽  
Divya Jyothi
Keyword(s):  
Nervous System ◽  
Differential Diagnosis ◽  
Nasal Cavity ◽  
Peripheral Nervous System ◽  
Nasal Polyp ◽  
Clinical Entity ◽  
Rare Clinical Entity ◽  
Excessive Bleeding ◽  
Ethmoidal Sinus

ABSTRACT Oncogenic osteoblastoma is a rare clinical entity in the peripheral nervous system (PNS). Its presentation is like a nasal polyp. One should keep the diagnosis of oncogenic osteoblastoma in mind as a differential diagnosis for mass in nasal cavity. Excessive bleeding during surgery should arouse the suspicion and the pathologist has to be sounded. A preliminary biopsy of the mass is to be considered. Immunohistochemistry (IHC) should be done, if the suspicion is strong.

Osteoid Osteoma of the Distal Phalanx: A Case Report

1987 ◽  
Vol 12 (3) ◽  
pp. 391-393
Author(s):  
G. M. McCARTEN ◽  
P. L. DIXON ◽  
D. R. MARSHALL
Keyword(s):  
Case Report ◽  
Osteoid Osteoma ◽  
Osteolytic Lesion ◽  
Middle Finger ◽  
Distal Phalanx ◽  
X Ray

A sixteen-year-old male presented with pain and swelling of the distal phalanx of his right middle finger. X-ray examination demonstrated an osteolytic lesion which at operation was found to be an osteoid osteoma.

The Croonian Lecture - Ionic movements and electrical activity in giant nerve fibres

1958 ◽  
Vol 148 (930) ◽  
pp. 1-37 ◽  
Keyword(s):  
Nervous System ◽  
Electrical Activity ◽  
Blood Vessels ◽  
Nerve Fibre ◽  
Peripheral Nerves ◽  
Tubular Structures ◽  
Large Structure ◽  
Nerve Fibres ◽  
Central Nervous Systems ◽  
Ionic Movements

During the course of an investigation into the central nervous systems of squids and cuttlefish, Professor J. Z. Young (1936 a , b ) noticed certain transparent tubular structures in the peripheral nerves. These must have seemed too large to be nerve fibres, and in a subsequent article Young (1944) remarked that he first took them to be blood vessels. However, on examining them more closely, he was able to prove that the tubes were, in fact, nerve fibres of exceptional size. Like many important discoveries, this was not an entirely new observation. It had been known since the time of Remak (1843) that Crustacea possessed giant nerve fibres, but with one exception the still larger fibres in cephalopods seem not to have been recognized as such. As Young pointed out, the exception was L. W. Williams who wrote a monograph on the squid which was published in 1909. In this monograph, Williams referred briefly to the large fibres in the nervous system. Williams did not commit himself as to the size of the fibres, but it is clear that he must have seen them. Thus he remarked that ‘The very size of the nerve processes has prevented their discovery, since it is well nigh impossible to believe that such a large structure can be a nerve fibre.’

scholarly journals Osteoid Osteoma: A Unique Presentation in a Child’s Lesser Toe

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Michel Bellemans ◽  
Nicolas de Saint-Aubin de Somerhausen ◽  
Phu Quoc Lê
Keyword(s):  
Young Adults ◽  
Differential Diagnosis ◽  
Case Report ◽  
Osteoid Osteoma ◽  
Excisional Biopsy ◽  
Definitive Diagnosis ◽  
Diagnosis And Treatment ◽  
X Ray ◽  
Nocturnal Pain ◽  
Prompt Diagnosis

Introduction. Osteoid osteoma is an uncommon, small, benign, self-limiting, and usually painful tumor of the skeleton. Diagnosis can be straightforward if seen in the usual locations as the femur and the tibia in young adults, who present with nocturnal pain, alleviated by salicylates. The diagnosis can be more challenging in the spine, pelvis, hand, or feet. Case Report. We report the case of an 11-year-old boy who was treated symptomatically for a painful toe since 10 months, without a definitive diagnosis. X-ray, MRI, and scintigraphy, along with the typical nocturnal pain and swelling of the toe, suggested an osteoid osteoma, confirmed by histology after excisional biopsy of the lesion. Conclusion. Osteoid osteoma should always be included in the differential diagnosis when it comes to nocturnal pain without systemic signs, even in unusual places in children. The awareness should lead to a prompt diagnosis and treatment.

scholarly journals Unilateral RS3PE in a Patient of Seronegative Rheumatoid Arthritis

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ankur Nandan Varshney ◽  
Nilesh Kumar ◽  
Ashutosh Tiwari ◽  
Ravi Anand ◽  
Sashi Ranjan Prasad ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Upper Extremities ◽  
Clinical Entity ◽  
Diagnosis And Treatment ◽  
High Dose ◽  
Rare Clinical Entity ◽  
Rare Presentation ◽  
Unilateral Disease ◽  
Prompt Diagnosis ◽  
Pitting Edema

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare but well-reported clinical entity. It is classically described as symmetrical involvement of both upper extremities. Asymmetrical involvement had also been reported, but unilateral presentation is very rare. We hereby report a case of unilateral RS3PE in a patient of seronegative rheumatoid arthritis which was initially misdiagnosed as cellulitis and was given high dose antibiotics without any significant improvement. Later a rheumatologic consultation leads to a prompt diagnosis, and treatment with steroids leads to dramatic reversal of symptoms. This case demonstrates the rare presentation of this rare clinical entity and highlights the necessity of awareness regarding unilateral disease to clinicians.

scholarly journals Spinal Osteoid Osteoma and scoliosis: who is the painful?

2019 ◽  
pp. 18-19
Keyword(s):  
Computed Tomography ◽  
Back Pain ◽  
Surgical Resection ◽  
Osteoid Osteoma ◽  
Bone Tumors ◽  
Young Patients ◽  
Lumbar Vertebra ◽  
Pathological Examination ◽  
X Ray ◽  
Benign Bone Tumors

Ten-year-old girl was referred to our clinic for back pain and stiffness of the spine. X-ray of the spine showed a dorsal scoliosis with no other abnormality (figure 1a). Computed Tomography (CT) showed the nidus in right pedicle of the 3rd lumbar vertebra (figure 1b). The diagnosis of Osteoid osteoma was retained and confirmed after surgical resection and pathological examination. Osteoid osteoma (O.O) accounts for 10 % to 20 % of benign bone tumors [1]. Up to 25% of all O.O are found in the spine. Two thirds of spinal O.O manifest as painful scoliosis [2]. The diagnosis of the tumor is usually delayed because easily missed on standard X-ray investigation. Systematic CT or MRI with dynamic contrast would be recommended for young patients presenting with painful scoliosis [3].

scholarly journals Early Detection of Diabetic Peripheral Neuropathy: A Focus on Small Nerve Fibres

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 165
Author(s):  
Jamie Burgess ◽  
Bernhard Frank ◽  
Andrew Marshall ◽  
Rashaad S. Khalil ◽  
Georgios Ponirakis ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Nerve Fibre ◽  
Diabetic Peripheral Neuropathy ◽  
Point Of Care ◽  
Unmet Need ◽  
Screening Tools ◽  
Nerve Fibres ◽  
Diagnostic Laboratory ◽  
Corneal Confocal Microscopy ◽  
Small Nerve

Diabetic peripheral neuropathy (DPN) is the most common complication of both type 1 and 2 diabetes. As a result, neuropathic pain, diabetic foot ulcers and lower-limb amputations impact drastically on quality of life, contributing to the individual, societal, financial and healthcare burden of diabetes. DPN is diagnosed at a late, often pre-ulcerative stage due to a lack of early systematic screening and the endorsement of monofilament testing which identifies advanced neuropathy only. Compared to the success of the diabetic eye and kidney screening programmes there is clearly an unmet need for an objective reliable biomarker for the detection of early DPN. This article critically appraises research and clinical methods for the diagnosis or screening of early DPN. In brief, functional measures are subjective and are difficult to implement due to technical complexity. Moreover, skin biopsy is invasive, expensive and lacks diagnostic laboratory capacity. Indeed, point-of-care nerve conduction tests are convenient and easy to implement however questions are raised regarding their suitability for use in screening due to the lack of small nerve fibre evaluation. Corneal confocal microscopy (CCM) is a rapid, non-invasive, and reproducible technique to quantify small nerve fibre damage and repair which can be conducted alongside retinopathy screening. CCM identifies early sub-clinical DPN, predicts the development and allows staging of DPN severity. Automated quantification of CCM with AI has enabled enhanced unbiased quantification of small nerve fibres and potentially early diagnosis of DPN. Improved screening tools will prevent and reduce the burden of foot ulceration and amputations with the primary aim of reducing the prevalence of this common microvascular complication.

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