Geriatric ED Patients Get Inappropriate Drugs

2009 ◽  
Vol 39 (13) ◽  
pp. 46
Author(s):  
BRUCE JANCIN
Keyword(s):  
Inappropriate Drugs

Potentially Inappropriate Medications Use in A Population of Iraqi Geriatric Outpatients According to Beers Criteria

2019 ◽  
Vol 10 (02) ◽  
Author(s):  
Ola Albaghdadi ◽  
Salam , Mohammad Hassan Morteza, Firas A Ahjel ◽  
Mohammad Hassan Morteza ◽  
Firas Aziz Rahi
Keyword(s):  
Health Care ◽  
Health Care Professionals ◽  
Public Health Issue ◽  
Beers Criteria ◽  
Potentially Inappropriate Medications ◽  
Cross Sectional ◽  
Face To Face ◽  
Inappropriate Drugs ◽  
Elderly Outpatients ◽  
Inappropriate Medications

Aims: Elderly in Iraq kept suffering multiple burdens, as they are a truly fragile and vulnerable segment. A major public health issue among elderly is adverse drug reactions. This study is aimed at contributing in overcoming this treatment gap by determining the prevalence of inappropriate medications used by a group of Iraqi elderly outpatients. Methods: A cross-sectional, questionnaire-based study was conducted in a sample of 85 Iraqi elderly aged ≥65 years of either gender. Participants had face-to-face interviews to answer a comprehensive questionnaire. Each drug taken by the patient was evaluated according to Beers criteria. Results: Females constituted 45.9% of the total. The average age was 69.9 years (± 4.6). Nearly 30% of the patients had 3 different diseases, and 17.8% had ≥4 different ones, with cardiovascular diseases were the most prevalent. Polypharmacy was notably identified in 47.1% of the total studied population. Twenty-eight out of 85 patients did not know the actual reason of taking at least one of their medications, and 42% were not taking their drugs as directed. Remarkably, 43.5% of patients were recognized as taking at least one medication to be avoided in elderly people according to the Beers criteria. The most common inappropriate drugs were glyburide, and proton-pump inhibitors. Conclusion: There was an obvious absence of any role of pharmacists in the health care system for our studied population. Health care professionals are encouraged to review the medications prescribed for geriatric patients using updated safety guidelines to prevent the risks associated with potentially inappropriate medications.

DANGEROUS AND INAPPROPRIATE DRUGS

The Lancet ◽  
1986 ◽  
Vol 327 (8496) ◽  
pp. 1488-1489 ◽  
Author(s):  
M.J.S. Langman
Keyword(s):  
Inappropriate Drugs

Optimizing pharmacotherapy for older patients

2017 ◽  
pp. 183-188 ◽  
Author(s):  
Denis O’Mahony
Keyword(s):  
Older People ◽  
Adverse Drug Events ◽  
Economic Consequences ◽  
High Risk Population ◽  
Potentially Inappropriate Medications ◽  
Inappropriate Drugs ◽  
Prescribing Omissions ◽  
The Relationship ◽  
Global Population ◽  
Inappropriate Medications

The prevalence of complex multimorbidity is increasing steadily in tandem with global population ageing. Complex multimorbidity is in turn intimately associated with polypharmacy, the relationship being one of cause-and-effect. Polypharmacy commonly leads to prescription of inappropriate drugs, resulting in a substantially higher risk of drug-related problems, principally adverse drug–drug and drug–disease interactions. These problems become manifest in the form of common geriatric symptoms such as falls, acute confusion, and incontinence and commonly result in increased healthcare utilization, including hospitalization, with obvious economic consequences. In addition, adverse drug reactions and adverse drug events lead to death in older people. The challenge of optimization of pharmacotherapy in older people with complex multimorbidity is a major one. There is increasing evidence that avoidance of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs) using validated PIM and PPO criteria lists leads to better and safer pharmacotherapy in this high-risk population.

scholarly journals AGING WITH HEMOPHILIA: THE CHALLENGE OF APPROPRIATE DRUG PRESCRIPTION

2019 ◽  
Vol 11 (1) ◽  
pp. e2019056 ◽  
Author(s):  
Pier Mannuccio Mannucci
Keyword(s):  
Viral Infections ◽  
Population Aging ◽  
Drug Prescription ◽  
Daily Intake ◽  
Cross Sectional ◽  
Inappropriate Drugs ◽  
Chronic Viral Infections ◽  
Related Risk ◽  
Hemophilia Treatment Centers ◽  
Drugs Interaction

In high-income countries persons with severe hemophilia (PWH) A and B are aging, like their age-matched peers without hemophilia from the general population. Aging is associated not only with the comorbidities stemming from their inherited bleeding disorder (arthropathy, chronic viral infections such as hepatitis and AIDS) but also with the multiple chronic ailments associated with aging (cancer, cardiovascular disease, COPD).  Multimorbidity is inevitably associated with polypharmacy, i.e., the chronic daily intake of at least five drugs, and with the related risk of severe adverse events associated with the use of inappropriate drugs and drug-drug interactions. Information on the pattern of drug prescription and usage by PWH is relatively scanty, but on the whole, the available data indicate that the rate of polypharmacy, as well as the risk of drug-drug interaction, is relatively low in PWH and better than that in their age peers without hemophilia followed by general practitioners. It is believed that this advantage results from the collaborative coordination on drug prescribing exerted, through their integration with practitioners and organ specialists, by specialized hemophilia treatment centers in the frame of comprehensive care programs. However, the available cross-sectional data were mainly obtained in relatively young PWH, so that there is a need to obtain more accurate data from the ongoing prospective studies that are being carried out in more and more progressively aging PWH.    Keywords: Hemophilia; Aging; Comorbidity; Drugs Interaction.  

scholarly journals Chronic Kidney Disease Management in General Practice: A Focus on Inappropriate Drugs Prescriptions

2020 ◽  
Vol 9 (5) ◽  
pp. 1346
Author(s):  
Maria Antonietta Barbieri ◽  
Michelangelo Rottura ◽  
Giuseppe Cicala ◽  
Rossella Mandraffino ◽  
Sebastiano Marino ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Predictive Factors ◽  
Descriptive Analysis ◽  
Prescribing Patterns ◽  
Lower Probability ◽  
Logistic Regression Models ◽  
Inappropriate Drugs ◽  
Nephrotoxic Drugs ◽  
Inappropriate Prescriptions

Nephrotoxic drugs prescriptions are often prescribed inappropriately by general practitioners (GPs), increasing the risk of chronic kidney disease (CKD). The aim of this study was to detect inappropriate prescriptions in patients with CKD and to identify their predictive factors. A retrospective study on patients with creatinine values recorded in the period 2014–2016 followed by 10 GPs was performed. The estimated glomerular filtration rate (eGFR) was used to identify CKD patients. The demographic and clinical characteristics and drugs prescriptions were collected. A descriptive analysis was conducted to compare the characteristics and logistic regression models to estimate the predictive factors of inappropriate prescriptions. Of 4098 patients with creatinine values recorded, 21.9% had an eGFR <60 mL/min/1.73 m2. Further, 56.8% received inappropriate prescriptions, with a significantly lower probability in subjects with at least a nephrologist visit (Adj OR 0.54 (95% CI 0.36–0.81)) and a greater probability in patients treated with more active substances (1.10 (1.08–1.12)), affected by more comorbidities (1.14 (1.06–1.230)), or with serious CKD (G4/G5 21.28 (7.36–61.57)). Nonsteroidal anti-inflammatory drugs (NSAIDs) were the most used contraindicated drugs (48.5%), while acetylsalicylic acid was the most inappropriately prescribed (39.5%). Our results highlight the inappropriate prescriptions for CKD authorized by GPs and underline the need of strategies to improve prescribing patterns.

scholarly journals Understanding Discomfort in Order to Appropriately Treat Fever

2019 ◽  
Vol 16 (22) ◽  
pp. 4487 ◽  
Author(s):  
Mattia Doria ◽  
Domenico Careddu ◽  
Flavia Ceschin ◽  
Maria Libranti ◽  
Monica Pierattelli ◽  
...  
Keyword(s):  
Social Media ◽  
Healthcare Professionals ◽  
International Guidelines ◽  
Inappropriate Drugs ◽  
Adequate Information ◽  
Antipyretic Treatment ◽  
Definition Of ◽  
Fever Phobia

Although national and international guidelines on the management of childhood and adolescent fever are available, some inadequate practices persist, both from parents and healthcare professionals. The main goal of bringing children’s temperature back to normal can lead to the choice of inappropriate drugs or non-necessary combination/alternation of antipyretic treatments. This behavior has been described in the last 35 years with the concept of fever-phobia, caused also by the dissemination of unscientific information and social media. It is therefore increasingly important that pediatricians continue to provide adequate information to parents in order to assess the onset of signs of a possible condition of the child’s discomfort rather than focusing only on temperature. In fact, there is no clear and unambiguous definition of discomfort in literature. Clarifying the extent of the feverish child’s discomfort and the tools that could be used to evaluate it would therefore help recommend that antipyretic treatment is appropriate only if fever is associated with discomfort.

The risk of polypharmacy and potentially inappropriate drugs in residential care dementia patients: tips from the PharE study

2020 ◽  
Author(s):  
Pietro Gareri ◽  
Antonino Maria Cotroneo ◽  
Maria Teresa Pontieri ◽  
Caterina Palleria ◽  
Giovambattista De Sarro
Keyword(s):  
Residential Care ◽  
Inappropriate Drugs ◽  
Dementia Patients
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