Glutathione-S-transferases M1 (GSTM1) and GSTT1 genotype, smoking, consumption of alcohol and tea and risk of esophageal and stomach cancers: a case-control study of a high-incidence area in Jiangsu Province, China

2002 ◽  
Vol 188 (1-2) ◽  
pp. 95-102 ◽  
Author(s):  
Chang-Ming Gao ◽  
Toshiro Takezaki ◽  
Jian-Zhong Wu ◽  
Zhong-You Li ◽  
Yan-Ting Liu ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Jiangsu Province ◽  
High Incidence ◽  
Gstt1 Genotype ◽  
Glutathione S Transferases ◽  
Control Study ◽  
High Incidence Area

Risk factors for hip fracture in a high incidence area: A case-control study from Oslo, Norway

1995 ◽  
Vol 5 (4) ◽  
pp. 239-246 ◽  
Author(s):  
H. E. Meyer ◽  
C. Henriksen ◽  
J. A. Falch ◽  
J. I. Pedersen ◽  
A. Tverdal
Keyword(s):  
Risk Factors ◽  
Hip Fracture ◽  
Case Control Study ◽  
Case Control ◽  
High Incidence ◽  
Control Study ◽  
High Incidence Area

scholarly journals Primary liver cancer and occupation in men: A case-control study in a high-incidence area in northern Italy

2001 ◽  
Vol 94 (6) ◽  
pp. 878-883 ◽  
Author(s):  
Stefano Porru ◽  
Donatella Placidi ◽  
Angela Carta ◽  
Umberto Gelatti ◽  
Maria Luisa Ribero ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Case Control Study ◽  
Primary Liver Cancer ◽  
Case Control ◽  
Northern Italy ◽  
High Incidence ◽  
Control Study ◽  
High Incidence Area

Analysis of glutathione S-transferase genes polymorphisms and the risk of schizophrenia in a sample of Iranian population

2011 ◽  
Vol 7 (2-4) ◽  
pp. 199-203 ◽  
Author(s):  
Farah Lotfi Kashani ◽  
Dor Mohammad Kordi-Tamandani ◽  
Roya Sahranavard ◽  
Mohammad Hashemi ◽  
Farzaneh Kordi-Tamandani ◽  
...  
Keyword(s):  
Genomic Dna ◽  
Case Control Study ◽  
Gene Interaction ◽  
Case Control ◽  
Glutathione S Transferase ◽  
Chain Reaction ◽  
Healthy Control ◽  
Glutathione S Transferases ◽  
Polymerase Chain ◽  
Control Study

Glutathione S-transferases (GSTs) are major intracellular antioxidants, which, impaired in their function, are involved in the progress of schizophrenia (SCZ). The aim of this case-control study was to investigate the association between the polymorphism of glutathione S-transferases M1 (GSTM1), T1 (GSTT1), the glutathione S-transferase P1 gene (GSTP1) and SCZ. We isolated genomic DNA from peripheral blood of 93 individuals with SCZ and 99 healthy control subjects' genotypes analyzing them for GSTM1, GSTT1 and GSTP1 using polymerase chain reaction. The analysis of the gene–gene interaction between GSTs indicated that the magnitude of the association was greater for the combined AG/GSTT1 & GSTM1 genotypes (OR = 2.51; 95% CI: 1.13–5.63, P = 0.02). The AG and combined AG + GG genotypes of GSTP1 increased the risk of SCZ (OR = 1.83; 95% CI: 0.94–3.75 and OR = 1.71; 95% CI: 0.92–3.19, respectively). The genotypes of GSTT/NULL, NULL/GSTM and NULL/NULL increased the risk of SCZ (OR = 2.05; 95% CI: 0.9–4.74; OR = 2.0; 95% CI: 1.68–2.31; and OR = 1.8; 95% CI: 0.57–2.46, respectively). The present study supports previous data that suggest that impairment in the function of GSTs genes may increase the risk of SCZ.

A Case–control Study of Diphtheria in the High Incidence City of Hyderabad, India

2016 ◽  
Vol 35 (3) ◽  
pp. 253-256 ◽  
Author(s):  
Ramesh Reddy Allam ◽  
Chengappa Kechamada Uthappa ◽  
Rebecca Duerst ◽  
Evan Sorley ◽  
Prasada Rao Udaragudi ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
High Incidence ◽  
Control Study

The human glutathione S-transferases: a case-control study of the incidence of the GST1 0 phenotype in patients with adenocarcinoma

1991 ◽  
Vol 12 (1) ◽  
pp. 25-28 ◽  
Author(s):  
Richard C. Strange ◽  
Balwir Matharoo ◽  
George C. Faulder ◽  
Peter Jones ◽  
William Cotton ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Glutathione S Transferases ◽  
Control Study

scholarly journals Somatotype and risk of breast cancer: a case-control study in Uruguay

2008 ◽  
Vol 11 (2) ◽  
pp. 215-227 ◽  
Author(s):  
Alvaro L. Ronco ◽  
Beatriz Mendoza ◽  
Ximena Varas ◽  
Sylvia Jaumandreu ◽  
Eduardo De Stéfani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Shape ◽  
Case Control Study ◽  
Positive Association ◽  
Case Control ◽  
Original Research ◽  
Menopausal Women ◽  
High Incidence ◽  
Study Population ◽  
Control Study

According to the evidence, there is a need for more thorough assessment and quantification of body size and shape and the risk of breast cancer. Using the somatotype methodology, we carried out an original research in order to explore possible associations between body shape and the risk of breast cancer in Uruguayan women. With this objective, 254 recent breast cancer cases and 1,000 frequency-matched healthy controls were interviewed on menstrual and reproductive story, and a series of skinfolds, circumferences and diameters were measured specifically to calculate somatotype. A positive association with breast cancer was found for high endomorphy (Odds Ratio [OR] = 2.82, p < 0.001), mainly among pre-menopausal women (OR = 4.98, p <0.001) and normoweight women (OR = 5.12, p = 0.002), whereas almost no differences were observed for mesomorphic and ectomorphic women. Analysis showed a high meso-endomorphic pattern in the study population. Further studies are needed to confirm the present results obtained in a country with high incidence of the disease.

scholarly journals Case-Control Study of Diet in Patients with Cervical Cancer or Precancerosis in Wufeng, a High Incidence Region in China

2012 ◽  
Vol 13 (10) ◽  
pp. 5299-5302 ◽  
Author(s):  
Yao Jia ◽  
Ting Hu ◽  
Chuan-Ying Hang ◽  
Ru Yang ◽  
Xiong Li ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Case Control Study ◽  
Case Control ◽  
High Incidence ◽  
Control Study

scholarly journals Determinants of Clinical Diphtheria After Sub National Diphtheria Immunization Days In 2012 At Bangkalan

2014 ◽  
Vol 2 (1) ◽  
pp. 71
Author(s):  
Feranita Utama ◽  
Chatarina Umbul Wahjuni ◽  
Santi Martini
Keyword(s):  
Logistic Regression ◽  
Multivariate Analysis ◽  
Case Control Study ◽  
Case Control ◽  
Bivariate Analysis ◽  
Chi Square ◽  
High Incidence ◽  
The Status ◽  
Simple Logistic ◽  
Control Study

ABSTRACTThe government had held sub-national diphtheria immunization days in 2012 to combat an outbreak of diphtheria in East Java province. However, there werestill regencies or cities which had high incidence and Bangkalanregencywas the highest. The research aimed to analyze the determinants of diphtheria in Bangkalan after SNIDs. This research was case control study with 31 subjects as case and 124 as control spread in 25 case villages and 25 control villages. Bivariate analysis used chi-square and simple logistic regression. Multivariate analysis used logistic regression. Bivariate analysisresult showed that individual and household variables that had associate with incidence of diphtheria in the Bangkalan after SNIDs of diphtheria vaccine in 2012 were DPT immunization status, the status of SNIDs, age, and mother's education level. In this study, there were not associate between village variables with diphtheria in the Bangkalan after SNIDs. Multivariate analysis result showed that had associate with incidence of diphtheria in Bangkalan after SNIDs were no DPT immunization (p=0,012; OR=4,765), incomplete DPT immunization (p=0,001; OR=6,276), 3-7 years of age (p=0,014; OR=15,137), 7-15 years of age (p=0,001;OR=41,984), and no immunization in SNIDs (p=0,020; OR=3,553). Conclusion, the dominantfactors that affected diphtheriainBangkalanwere status of DPTimmunization, ageand the SNIDs of diphtheria. Recommendation, DPTimmunizationshould becomplete, boosterimmunization should be needed, monitoring theimplementation ofsubPIN should be strict, especially inschool, and thecoverage ofDPT3andsubPIN should be increased and its report should be improved.Keywords: diphtheria, sub-nationaldiphtheriaimmunization days, DPT                              immunization

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