Poster #S227 REMEMBERING DAILY COGNITIVE FUNCTIONING IN SUBJECTS AT ULTRA-HIGH RISK FOR PSYCHOSIS: A CROSS-SECTIONAL STUDY ON EVERYDAY MANIFESTATIONS OF COGNITIVE DEFICITS IN AN ULTRA-HIGH RISK COHORT

OBJECTIVE: Cerebrovascular disease (CVD) is associated with cognitive deficits. This cross-sectional study examines differences among healthy elderly controls and patients with vascular mild cognitive impairment (VaMCI) and vascular dementia (VaD) in performances on CAMCOG subscales. METHOD: Elderly individuals (n=61) were divided into 3 groups, according to cognitive and neuroimaging status: 16 controls, 20 VaMCI and 25 VaD. VaMCI and VaD individuals scored over 4 points on the Hachinski Ischemic Scale. RESULTS: Significant differences in total CAMCOG scores were observed across the three groups (p<0.001). VaD subjects performed worse than those with VaMCI in most CAMCOG subscales (p<0.001). All subscales showed differences between controls and VaD (p<0.001). Performance on abstract thinking showed difference between VaMCI and controls (p<0.001). CONCLUSION: CAMCOG discriminated controls from VaMCI and VaD. Assessment of abstract thinking may be useful as a screening item for diagnosis of VaMCI.

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A cross-sectional study of antenatal depressive symptoms in women at high risk for gestational diabetes mellitus

Journal of Psychosomatic Research ◽

10.1016/j.jpsychores.2015.05.015 ◽

2015 ◽

Vol 79 (6) ◽

pp. 646-650 ◽

Cited By ~ 4

Author(s):

Elina Engberg ◽

Beata Stach-Lempinen ◽

Niina Sahrakorpi ◽

Kristiina Rönö ◽

Risto P. Roine ◽

...

Keyword(s):

Diabetes Mellitus ◽

Depressive Symptoms ◽

High Risk ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Antenatal Depressive Symptoms

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Prevalence, Risk Factors, and Comorbidities of Obstructive Sleep Apnea Risk Among a Working Population in Kuwait: A Cross-Sectional Study

Frontiers in Neurology ◽

10.3389/fneur.2021.620799 ◽

2021 ◽

Vol 12 ◽

Author(s):

Husain Al-Qattan ◽

Hamad Al-Omairah ◽

Khaled Al-Hashash ◽

Fahad Al-Mutairi ◽

Mohammad Al-Mutairat ◽

...

Keyword(s):

Risk Factors ◽

Obstructive Sleep Apnea ◽

High Risk ◽

Cross Sectional Study ◽

Health Conditions ◽

Sectional Study ◽

Working Population ◽

Cross Sectional ◽

Working Adults ◽

Obstructive Sleep

Background: Obstructive sleep apnea (OSA) affects a considerable proportion of adults globally and is associated with elevated morbidity and mortality. Given the lack of epidemiologic data on the burden of OSA in Kuwait, this study sought to estimate its prevalence, associated risk factors, and comorbid conditions among a working population in Kuwait.Methods: This was a cross-sectional study of a sample of working adults (n = 651) from public institutions in Kuwait. High/low risk for OSA was ascertained according to the Berlin Questionnaire criteria. Participants self-reported their coexisting health conditions. Associations were assessed using Poisson regression with robust variance estimation; adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs) were estimated.Results: Overall, 20.0% (130/651) of participants were classified as being at high risk for OSA, with more male than female subjects being at high risk (24.0% [56/233] vs. 17.7% [74/418], P = 0.053), though this difference did not gain statistical significance. Moreover, a high risk for OSA was more common among older and obese subjects. Factors associated with increased prevalence of a high risk for OSA included current smoking status (aPR = 1.58, 95% CI: 1.02–2.06), longer hours spent watching television (1.76, 1.10–2.81), and lower self-perceived physical health (2.11, 1.15–3.87). However, decreasing trends in the prevalence of high risk for OSA were observed with frequent engagement in vigorous physical activity and longer nightly sleep duration. Compared to those at a low risk for OSA, the subjects at high risk for OSA were more likely to have insomnia disorder (2.83, 1.81–4.41), diabetes (1.94, 1.15–3.27), hypertension (3.00, 1.75–5.16), and depression (4.47, 1.80–11.08).Conclusion: This study estimated that 1/5 of working adults in Kuwait were at high risk for OSA, and the prevalence varied according to personal characteristics and lifestyle factors. Also, a high risk for OSA classification was associated with multiple comorbid health conditions.

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Relationship between the non-HDLc-to-HDLc ratio and carotid plaques in a high stroke risk population: A cross-sectional study in China

10.21203/rs.3.rs-26172/v3 ◽

2020 ◽

Author(s):

Yan Liu ◽

Zhenwen Zhang ◽

Binlan Xia ◽

Liping Wang ◽

Hengzhong Zhang ◽

...

Keyword(s):

High Risk ◽

Stroke Risk ◽

Heart Diseases ◽

Density Lipoprotein ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Carotid Plaques ◽

Lack Of Exercise ◽

The Relationship

Abstract Background: Evidence on the association between the non-high-density lipoprotein cholesterol (non-HDLc)-to-high-density lipoprotein cholesterol (HDLc) ratio (non-HDLc/HDLc) and carotid plaques is still limited. This study aims to assess the relationship between the non-HDLc/HDLc and carotid plaques in a population with a high risk of stroke.Methods: A cross-sectional study based on the community was conducted in Yangzhou, China. Residents (no younger than 40 years old) underwent questionnaire interviews, physical examinations, and laboratory testing during 2013-2014. The subjects with a high risk of stroke were further selected (at least three of eight risk factors including hypertension, atrial fibrillation, type 2 diabetes mellitus, dyslipidaemia, smoking, lack of exercise, overweight, and family history of stroke) or a transient ischaemic attack (TIA) or stroke history. Carotid ultrasonography was then performed on the high stroke risk participants. Carotid plaque was defined as a focal carotid intima-media thickness (cIMT) ≥1.5 cm or a discrete structure protruding into the arterial lumen at least 50% of the surrounding cIMT. Logistic regression was employed to evaluate the relationship between the non-HDLc/HDLc and carotid plaques.Results: Overall, 839 subjects with a high risk of stroke were ultimately included in the analysis, and carotid plaques were identified in 341 (40.6%) of them. Participants in the highest non-HDLc/HDLc tertile group presented a higher proportion of carotid plaques than did those in the other two groups. After adjustment for other confounders, each unit increase in the non-HDLc/HDLc was significantly associated with carotid plaques (OR 1.55, 95%CI 1.28-1.88). In the subgroup analysis, the non-HDLc/HDLc was positively and significantly associated with the presence of carotid plaques in most subgroups. Additionally, the non-HDLc/HDLc interacted significantly with three stratification variables, including sex (OR 1.31 for males vs. OR 2.37 for females, P interaction = 0.016), exercise (OR 1.18 for subjects without lack of exercise vs. OR 1.99 for subjects with lack of exercise, P interaction = 0.004) and heart diseases (OR 1.40 for subjects without heart diseases vs. OR 3.12 for subjects with heart diseases, P interaction = 0.033). Conclusion: The non-HDLc/HDLc was positively associated with the presence of carotid plaques in a Chinese high stroke risk population. A prospective study or randomized clinical trial of lipid-lowering therapy in the Chinese population is needed to evaluate their causal relationship.

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