scholarly journals 364: Effect of concentrated CF mucus on mucociliary transport efficiency

2021 ◽  
Vol 20 ◽  
pp. S173
Author(s):  
M. Gutay ◽  
B. Button
2021 ◽  
Vol 3 (2) ◽  
pp. 262-271
Author(s):  
Pablo Reséndiz-Vázquez ◽  
Ricardo Román-Ancheyta ◽  
Roberto León-Montiel

Transport phenomena in photosynthetic systems have attracted a great deal of attention due to their potential role in devising novel photovoltaic materials. In particular, energy transport in light-harvesting complexes is considered quite efficient due to the balance between coherent quantum evolution and decoherence, a phenomenon coined Environment-Assisted Quantum Transport (ENAQT). Although this effect has been extensively studied, its behavior is typically described in terms of the decoherence’s strength, namely weak, moderate or strong. Here, we study the ENAQT in terms of quantum correlations that go beyond entanglement. Using a subsystem of the Fenna–Matthews–Olson complex, we find that discord-like correlations maximize when the subsystem’s transport efficiency increases, while the entanglement between sites vanishes. Our results suggest that quantum discord is a manifestation of the ENAQT and highlight the importance of beyond-entanglement correlations in photosynthetic energy transport processes.


Fractals ◽  
2019 ◽  
Vol 27 (08) ◽  
pp. 1950142
Author(s):  
JINZE XU ◽  
KELIU WU ◽  
RAN LI ◽  
ZANDONG LI ◽  
JING LI ◽  
...  

Effect of nanoscale pore size distribution (PSD) on shale gas production is one of the challenges to be addressed by the industry. An improved approach to study multi-scale real gas transport in fractal shale rocks is proposed to bridge nanoscale PSD and gas filed production. This approach is well validated with field tests. Results indicate the gas production is underestimated without considering a nanoscale PSD. A PSD with a larger fractal dimension in pore size and variance yields a higher fraction of large pores; this leads to a better gas transport capacity; this is owing to a higher free gas transport ratio. A PSD with a smaller fractal dimension yields a lower cumulative gas production; this is because a smaller fractal dimension results in the reduction of gas transport efficiency. With an increase in the fractal dimension in pore size and variance, an apparent permeability-shifting effect is less obvious, and the sensitivity of this effect to a nanoscale PSD is also impaired. Higher fractal dimensions and variances result in higher cumulative gas production and a lower sensitivity of gas production to a nanoscale PSD, which is due to a better gas transport efficiency. The shale apparent permeability-shifting effect to nanoscale is more sensitive to a nanoscale PSD under a higher initial reservoir pressure, which makes gas production more sensitive to a nanoscale PSD. The findings of this study can help to better understand the influence of a nanoscale PSD on gas flow capacity and gas production.


Langmuir ◽  
2021 ◽  
Author(s):  
Meike Reginka ◽  
Hai Hoang ◽  
Özge Efendi ◽  
Maximilian Merkel ◽  
Rico Huhnstock ◽  
...  

2002 ◽  
Vol 283 (2) ◽  
pp. L329-L335 ◽  
Author(s):  
Stephen T. Ballard ◽  
Laura Trout ◽  
Anil Mehta ◽  
Sarah K. Inglis

Because of its possible importance in cystic fibrosis (CF) pulmonary pathogenesis, the effect of anion and liquid secretion inhibitors on airway mucociliary transport was examined. When excised porcine tracheas were treated with ACh to induce gland liquid secretion, the rate of mucociliary transport was increased nearly threefold from 2.5 ± 0.5 to 6.8 ± 0.8 mm/min. Pretreatment with both bumetanide and dimethylamiloride (DMA), to respectively inhibit Cl− and HCO[Formula: see text]secretion, significantly reduced mucociliary transport in the presence of ACh by 92%. Pretreatment with the anion channel blocker 5-nitro-2-(3-phenylpropylamino)benzoic acid similarly reduced mucociliary transport in ACh-treated airways by 97%. These agents did not, however, reduce ciliary beat frequency. Luminal application of benzamil to block liquid absorption significantly attenuated the inhibitory effects of bumetanide and DMA on mucociliary transport. We conclude that anion and liquid secretion is essential for normal mucociliary transport in glandular airways. Because the CF transmembrane conductance regulator protein likely mediates Cl−, HCO[Formula: see text], and liquid secretion in normal glands, we speculate that impairment of gland liquid secretion significantly contributes to defective mucociliary transport in CF.


2013 ◽  
Vol 284-287 ◽  
pp. 147-151
Author(s):  
Tso Fu Mark Chang ◽  
Takashi Nagoshi ◽  
Chiemi Ishiyama ◽  
Tatsuo Sato ◽  
Masato Sone

Ultrathin (2 emulsion (SCE). Incomplete coverage of the Cu plate, the working electrode, by electroplated Ni and non-uniform Ni films with defects were obtained when conventional electroplating at 1 A/dm2 with 30 sec of deposition time was used. When electroplating with SCE (ESCE) was applied, complete coverage, defect-free and uniform UTNFs were obtained. SEM and AFM showed surface morphology of the UTNFs was covered by spherical-shaped particles with ~10 nm in diameter, which was expected to be individual Ni grains because the size was consistent with grain size of Ni films reported when ESCE was applied. High H2 solubility in CO2, periodic-plating-characteristic after applying ESCE, and improved transport efficiency of the reactive species are believed to be the main reasons to cause effects of grain refinement and suppression in formation of the defects. Thickness of the UTNFs was 11.97±1.82 nm when the deposition time was 15 sec, and the thickness increased to 38.45±1.71 nm when the deposition time was increased to 45 sec.


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