scholarly journals The Quest to solve the HL-LHC data access puzzle

2020 ◽  
Vol 245 ◽  
pp. 04027
Author(s):  
X. Espinal ◽  
S. Jezequel ◽  
M. Schulz ◽  
A. Sciabà ◽  
I. Vukotic ◽  
...  
Keyword(s):  
Data Storage ◽  
Working Group ◽  
Data Access ◽  
Current Data ◽  
Resource Needs ◽  
Lake Model ◽  
New Concepts ◽  
Depth Analysis ◽  
Group Members ◽  
The Impact

HL-LHC will confront the WLCG community with enormous data storage, management and access challenges. These are as much technical as economical. In the WLCG-DOMA Access working group, members of the experiments and site managers have explored different models for data access and storage strategies to reduce cost and complexity, taking into account the boundary conditions given by our community.Several of these scenarios have been evaluated quantitatively, such as the Data Lake model and incremental improvements of the current computing model with respect to resource needs, costs and operational complexity.To better understand these models in depth, analysis of traces of current data accesses and simulations of the impact of new concepts have been carried out. In parallel, evaluations of the required technologies took place. These were done in testbed and production environments at small and large scale.We will give an overview of the activities and results of the working group, describe the models and summarise the results of the technology evaluation focusing on the impact of storage consolidation in the form of Data Lakes, where the use of streaming caches has emerged as a successful approach to reduce the impact of latency and bandwidth limitation.We will describe the experience and evaluation of these approaches in different environments and usage scenarios. In addition we will present the results of the analysis and modelling efforts based on data access traces of the experiments.

scholarly journals Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society

2021 ◽  
Vol 12 ◽  
Author(s):  
Stephanie Lucas ◽  
Michaela Tencerova ◽  
Benoit von der Weid ◽  
Thomas Levin Andersen ◽  
Camille Attané ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Adipose Tissue ◽  
Working Group ◽  
Cell Types ◽  
Bone Marrow Adipose Tissue ◽  
Marrow Adipose Tissue ◽  
Marrow Adiposity ◽  
Group Members ◽  
Number Of Publications ◽  
Different Sources

Over the last two decades, increased interest of scientists to study bone marrow adiposity (BMA) in relation to bone and adipose tissue physiology has expanded the number of publications using different sources of bone marrow adipose tissue (BMAT). However, each source of BMAT has its limitations in the number of downstream analyses for which it can be used. Based on this increased scientific demand, the International Bone Marrow Adiposity Society (BMAS) established a Biobanking Working Group to identify the challenges of biobanking for human BMA-related samples and to develop guidelines to advance establishment of biobanks for BMA research. BMA is a young, growing field with increased interest among many diverse scientific communities. These bring new perspectives and important biological questions on how to improve and build an international community with biobank databases that can be used and shared all over the world. However, to create internationally accessible biobanks, several practical and legislative issues must be addressed to create a general ethical protocol used in all institutes, to allow for exchange of biological material internationally. In this position paper, the BMAS Biobanking Working Group describes similarities and differences of patient information (PIF) and consent forms from different institutes and addresses a possibility to create uniform documents for BMA biobanking purposes. Further, based on discussion among Working Group members, we report an overview of the current isolation protocols for human bone marrow adipocytes (BMAds) and bone marrow stromal cells (BMSCs, formerly mesenchymal), highlighting the specific points crucial for effective isolation. Although we remain far from a unified BMAd isolation protocol and PIF, we have summarized all of these important aspects, which are needed to build a BMA biobank. In conclusion, we believe that harmonizing isolation protocols and PIF globally will help to build international collaborations and improve the quality and interpretation of BMA research outcomes.

A multispecialty approach to immuno-oncology education for community providers.

2019 ◽  
Vol 37 (8_suppl) ◽  
pp. 80-80
Author(s):  
Tara Perloff ◽  
Monique Dawkins ◽  
Jennie Robertson Crews ◽  
Jeffrey P. Gregg ◽  
Ivo Abraham ◽  
...  
Keyword(s):  
Working Group ◽  
Community Setting ◽  
Educational Interventions ◽  
Educational Opportunities ◽  
Systemic Review ◽  
Training And Education ◽  
Oncology Education ◽  
Working Groups ◽  
Group Members ◽  
Cancer Immunotherapies

80 Background: The Association of Community Cancer Centers (ACCC) Immuno-Oncology Institute was developed in 2015 to prepare all members of the multidisciplinary cancer care team for the complex implementation of immuno-oncology in the community setting. Today, with more than 50 cancer immunotherapy indications and over 2,500 clinical trials with cancer immunotherapies, the challenges and issues related to recognizing and managing immune-related adverse events (irAEs) have grown even more complex for community practitioners. Methods: The ACCC Immuno-Oncology Institute assembled 4 working groups focused on addressing the diverse issues around the delivery and management of patients on cancer immunotherapies. The working groups were divided by 4 topics: staff training and education; multispecialty care coordination and communication; telemedicine; and big data. A detailed systemic review of the literature was conducted for each topic in the context of immuno-oncology, to determine the current landscape of information and available resources. The findings were then shared with the working group members and collaborative discussions ensued over 12 virtual committee meetings. The 19 working group members are diverse by discipline, including specialties such as emergency medicine, dermatology, primary care, survivorship, pathology, and academic researchers. Results: The ACCC Working Group Summit convened in September 2018 to develop innovative educational opportunities for community practitioners related to managing irAEs across the 4 topic areas. Eight unique action plans were developed by working group members. Conclusions: For each of the 4 key areas, working group members identified a list of opportunities that would improve how clinicians are managing irAEs for patients being treated with immunotherapy. It is critical for future educational interventions to encompass the multispecialty team perspective related to the management of irAEs.

Using consistent terms in precision medicine to eliminate patient confusion.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e24164-e24164 ◽  
Author(s):  
Nikki A. Martin ◽  
Sue J. Friedman ◽  
Claire Saxton ◽  
Ronit Yarden ◽  
Stacie Lindsey ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Patient Education ◽  
Precision Medicine ◽  
Working Group ◽  
Cancer Type ◽  
Plain Language ◽  
Framework Analysis ◽  
Biomarker Testing ◽  
Group Members ◽  
Germline Testing

e24164 Background: Biomarker testing has advanced precision medicine in cancer. However, not all eligible patients benefit from biomarker-driven therapies due to suboptimal testing rates. A working group of 20 patient advocacy groups representing solid/hematologic malignancies, three professional societies, and 18 pharmaceutical and diagnostics companies identified patient confusion inconsistent testing terms as a possible contributing factor to biomarker testing underutilization. The group aimed to address patients’ confusion by identifying and adopting consistent, plain language terms for biomarker and germline genetic testing that are applicable across cancer types. Methods: Following a stakeholder roundtable discussion on barriers to precision medicine, working group members participated in interviews on their goals for consistent testing terminology for their constituents. We then conducted a framework analysis covering five themes: available testing by cancer type; purpose of test; biospecimen source; terms used in patient education; and preferred plain language term. Working group members were surveyed on preferences for germline testing terminology and also deployed a preliminary patient survey to their constituents to gain insight on preferences for germline testing terms. Results: Interviews, framework analysis, and surveys revealed notable differences across cancer communities. We identified at least 33 different terms related to biomarker, genetic and genomic testing being used in patient education and clinical care among the different cancer communities and stakeholders. Terminology was complicated by the variety of testing modalities and gene mutations tested for across cancers. Following multiple discussions, working group members agreed on two umbrella terms to distinguish between somatic and germline testing with additional context for specific cancer communities. “Biomarker testing” was selected as the somatic testing term. “Genetic testing for an inherited mutation” and “genetic testing for inherited cancer risk” were selected as preferred germline testing terms. Conclusions: Our findings highlight the disparate testing terminology landscape and the need for consistent terms to reduce patient confusion, improve communication, facilitate shared decision-making and assure concordance in policy development.

scholarly journals MODAL SOSIAL YANG DIMILIKI ANGGOTA KELOMPOK KERJA (POKJA) PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) DALAM UPAYA PENERAPAN PERILAKU HIDUP BERSIH DAN SEHAT (STUDI DESKRIPTIF DI SEKOLAH MENENGAH PERTAMA NEGERI 107 JAKARTA)

2015 ◽  
Vol 16 (2) ◽  
Author(s):  
Annisa Sherliany ◽  
Wisni Bantarti
Keyword(s):  
Social Capital ◽  
Data Collection ◽  
Working Group ◽  
Qualitative Approach ◽  
Healthy Living ◽  
Literature Study ◽  
Descriptive Research ◽  
The Social ◽  
Group Members ◽  
Depth Interviews

The purpose of this research to describe the social capital that is owned by the working group members of PHBS of SMP Negeri 107 Jakarta in an effort to implement a clean and healthy living behavior. This research uses a qualitative approach and is a descriptive research through data collection techniques in-depth interviews, observation, and literature study. The results of this research shows that social capital is owned by members of the working group of PHBS of SMP Negeri 107 Jakarta can support its success in an effort to implement clean and healthy living behavior.

scholarly journals Connecting the Urological Community : The #UroSoMe Experience

2019 ◽  
Vol 2 (2) ◽  
pp. e20-e29 ◽  
Author(s):  
Kalyan Gudaru ◽  
Leonardo Tortolero Blanco ◽  
Daniele Castellani ◽  
Hegel Trujillo Santamaria ◽  
Marcela Pelayo-Nieto ◽  
...  
Keyword(s):  
Social Media ◽  
Working Group ◽  
Efficient Manner ◽  
The Social ◽  
Social Media Platforms ◽  
Twitter Account ◽  
Group Members ◽  
Twitter Users ◽  
Use Of Social Media ◽  
Twitter Activity

Background and Objectives There is an increasing use of social media amongst the urological community. However, it is difficult to identify urological data on various social media platforms in an efficient manner. We proposed a hashtag, #UroSoMe, to be used when posting urology-related content in the social media platforms. The objectives of this article are to describe how #UroSoMe was developed, and to report the data of the first month of #UroSoMe.   Material and Methods The hashtag, #UroSoMe, was introduced to the urological community. The #UroSoMe working group was formed, and the members actively invited and encouraged people to use the hashtag #UroSoMe when posting urology-related contents. After the #UroSoMe (@so_uro) platform on twitter had grown to more than 300 users, the first live event of online case discussion, i.e. #LiveCaseDiscussions, was conducted. A prospective observational study of the hashtag #UroSoMe Twitter activity during the first month of its usage from 14 December 2018 to 13 January 2019 was evaluated. Outcome measures included number of users, number of tweets, user location, top tweeters, top hashtags used and interactions. Analysis was performed using NodeXL (Social Media Research Foundation; California, USA; https://www.smrfoundation.org/nodexl/), Symplur (https:// www.symplur.com) and Twitonomy (https://www.twitonomy.com).   Results The first month of #UroSoMe activity documented 1373 tweets/retweets by 1008 tweeters with 17698 mentions and 1003 replies. The #LiveCaseDiscussions was able to achieve a potential reach of 2,033,352 Twitter users. The top tweets mainly included cases presented by #UroSoMe working group members during #LiveCaseDiscussions. The twitonomy map showed participation from 214 geographical locations. The major groups of participants using the hashtag #UroSoMe were ‘Researcher/Academic’ and ‘Doctor’. The twitter account of #UroSoMe (@so_uro) has now grown to more than 1000 followers.   Conclusions Social media is an excellent platform for interaction amongst the urological community. The results demonstrated that #UroSoMe was able to achieve wide spread engagement from all over the world.

The BIALL Annual Law Firm Library Survey 2015/2016

2017 ◽  
Vol 17 (2) ◽  
pp. 102-108 ◽  
Author(s):  
Keyword(s):  
Working Group ◽  
Law Firm ◽  
Standard Practice ◽  
Survey Results ◽  
Group Members ◽  
The Law ◽  
Firm Survey

AbstractThe BIALL annual law firm survey was launched in October 2016. The aim was to understand standard practice across the law firm library sector and to benchmark certain aspects of a library's service against other firms, providing a year-on-year comparison of how the profession is changing. This is an overview of how the survey came about and a summary of the key findings from the first year's results. It was written by the Working Group members. The full survey results can be found on the BIALL website1.

A Social-Academic Network Analysis of the EURO Working Group on DSS

2010 ◽  
Vol 2 (4) ◽  
pp. 13-36 ◽  
Author(s):  
Rahma Bouaziz ◽  
Tiago Simas ◽  
Fátima Dargam ◽  
Rita Ribeiro ◽  
Pascale Zaraté
Keyword(s):  
Social Network ◽  
Decision Support ◽  
Network Analysis ◽  
Working Group ◽  
Analytical Data ◽  
The Social ◽  
Group Members ◽  
Academic Network ◽  
Collaboration Dynamics ◽  
New Research

This paper addresses aspects of the social network analysis (SNA) performed on the social-academic network implemented for the EURO Working Group on Decision Support Systems (EWG-DSS). The EWG-DSS network has more than 105 members and is defined with the objective of analysing and representing the various relationships that academically link the group members, as well as evaluating the group’s collaboration dynamics. This paper shows graphical representations and discusses their corresponding interpretation and analytical data. This work is part of the study carried out within the underlying project of the EWG-DSS social-academic network to understanding how the group interacts, as well as encouraging new research and promoting further collaboration among the EWG-DSS group members.

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