scholarly journals Re-emergence of infectious diseases associated with the past

2021 ◽  
Vol 2 (4) ◽  
pp. e140
Author(s):  
Priya Venkatesan
Keyword(s):  
Cells ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 113 ◽  
Author(s):  
Stephanie Maia Acuña ◽  
Lucile Maria Floeter-Winter ◽  
Sandra Marcia Muxel

An inflammatory response is essential for combating invading pathogens. Several effector components, as well as immune cell populations, are involved in mounting an immune response, thereby destroying pathogenic organisms such as bacteria, fungi, viruses, and parasites. In the past decade, microRNAs (miRNAs), a group of noncoding small RNAs, have emerged as functionally significant regulatory molecules with the significant capability of fine-tuning biological processes. The important role of miRNAs in inflammation and immune responses is highlighted by studies in which the regulation of miRNAs in the host was shown to be related to infectious diseases and associated with the eradication or susceptibility of the infection. Here, we review the biological aspects of microRNAs, focusing on their roles as regulators of gene expression during pathogen–host interactions and their implications in the immune response against Leishmania, Trypanosoma, Toxoplasma, and Plasmodium infectious diseases.


PEDIATRICS ◽  
1956 ◽  
Vol 18 (1) ◽  
pp. 160-162 ◽  
Author(s):  
ROBERT J. HAGGERTY ◽  
R. CANNON ELEY

In the past 2 years we have seen 2 patients at the Children's Medical Center, who, while receiving cortisone therapy, developed varicella and died following a state of shock within a few days after the appearance of the vesicles. Post-mortem examinations of these patients revealed hemorrhagic vesicles throughout all viscera. In 1 case the virus of varicella was grown from vesicle fluid, heart blood, and lung. Since fatalities from varicella in childhood are so rarely encountered, even by physicians with vast experience in the field of infectious diseases, and since the clinical course of the infection in these two patients was so fulminating, the possible relationship of cortisone administration was raised.


2013 ◽  
Vol 88 (1) ◽  
pp. 128-129 ◽  
Author(s):  
Paulo Ricardo Criado ◽  
Lívia Delgado ◽  
Gustavo Alonso Pereira

Dermoscopy has being used over the past twenty years as a noninvasive aid in the diagnosis of innumerable skin conditions, including infectious diseases and infestations (Entodermoscopy).Tinea nigra is a superficial phaeohyfomycosis that affects mainly the glabrous skin of palms and soles. We describe a 14 year-old girl with a three-month history of an enlarging brown patch of her hand diagnosed as Tinea Nigra following clinical and dermoscopy examination.These images emphasize the importance of dermoscopy as a diagnostic tool in the daily routine of dermatologists.


2020 ◽  
Vol 8 (1) ◽  
pp. 1-3
Author(s):  
Venkata Ramana Kandi

The emergence and re-emergence of infectious diseases are not uncommon to humans. We have been seeing this, repeated many a time in the past, that the new/novel microbial species emerge and pose a potential threat to the whole of mankind. Among those infectious diseases which threatened mankind, the Smallpox virus appears to have had the greatest impact. Smallpox virus was suspected to be present on the earth since 10,000 B.C., but its presence and the effect on humans was established only in the late 18th century to the early 20th century when people suffered from its consequences. Most people (>75%) infected with smallpox died, leaving a sense of doom among humans. Later, or probably during the same time, there was the emergence of an infectious disease called “plague”, which swept across many countries and caused a lot of mortality. This disease was also called the black death, due to the nature of lesions caused and the thousands of people who were dying in very less time. We have also seen the emergence of a novel influenza virus, the Spanish flu (1918) which caused a severe pandemic. Interestingly, all these infectious diseases caused pandemics involving several countries, and causing increased mortality, especially in the European continent. In this editorial I discuss the significance of the most recent pandemic caused by the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV2), also called Coronavirus disease-19 (COVID-19).


PEDIATRICS ◽  
1973 ◽  
Vol 52 (4) ◽  
pp. 483-484
Author(s):  
Samuel L. Katz

The pediatrician has always been among those physicians most sensitive and attentive to the principles and practice of preventive medicine. For the past three decades immunization against infectious diseases has constituted a major aspect of his activities. Many of the vaccines utilized today are the products of research and of investigators fostered by pediatric institutions. The success of these immunizing agents has had profound, beneficial effects on childhood morbidity and mortality. This same success has enabled the pediatrician in his practice and in his research to focus greater energies on many of the other challenges to the health of infants and children.


Author(s):  
Sónia Dias ◽  
Ana Gama ◽  
Ana Maria Tavares ◽  
Vera Reigado ◽  
Daniel Simões ◽  
...  

Sub-Saharan African migrants (SSAMs) have been disproportionately affected by infectious disease burden. We aimed to identify correlates of HIV, past sexually transmitted infection (STI) and past Tuberculosis infection (TB), as well as examine HIV seropositivity unawareness and testing history among SSAMs. A venue-based sample of 790 SSAMs completed a cross-sectional biobehavioral survey on sexual practices, HIV testing and self-reported infectious diseases; an HIV rapid test was offered. Overall, 5.4% of participants were HIV-positive and 16.7% reported a past STI. Odds of being HIV positive or having a past STI were higher among participants with low socioeconomic status and who experienced violence from a partner. Increased odds of having a past STI were also found among long-term migrants and those who reported sexual risk behaviors. In total, 4.1% of participants had TB in the past; these were more likely male and HIV positive. Unawareness of HIV-positive status was notably high (35%). Half of the participants had never been tested for HIV before, including over a third of those who had STI or TB in the past. Efforts are needed to reduce missed opportunities for HIV/STIs prevention and uptake of HIV testing among SSAMs through more integrated care, while addressing social determinants of infectious diseases.


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