Varicella and Cortisone

PEDIATRICS ◽  
1956 ◽  
Vol 18 (1) ◽  
pp. 160-162 ◽  
Author(s):  
ROBERT J. HAGGERTY ◽  
R. CANNON ELEY
Keyword(s):  
Infectious Diseases ◽  
Clinical Course ◽  
Medical Center ◽  
Post Mortem ◽  
The Past ◽  
Vesicle Fluid ◽  
Heart Blood ◽  
Cortisone Therapy ◽  
Relationship Of

In the past 2 years we have seen 2 patients at the Children's Medical Center, who, while receiving cortisone therapy, developed varicella and died following a state of shock within a few days after the appearance of the vesicles. Post-mortem examinations of these patients revealed hemorrhagic vesicles throughout all viscera. In 1 case the virus of varicella was grown from vesicle fluid, heart blood, and lung. Since fatalities from varicella in childhood are so rarely encountered, even by physicians with vast experience in the field of infectious diseases, and since the clinical course of the infection in these two patients was so fulminating, the possible relationship of cortisone administration was raised.

COVID-19 in children: Pathogenesis and current status

2020 ◽  
Author(s):  
Lawrence Frenkel ◽  
Fernando Gomez ◽  
Joseph A Bellanti
Keyword(s):  
Respiratory Disease ◽  
Respiratory Symptoms ◽  
Distress Syndrome ◽  
Clinical Course ◽  
Current Status ◽  
Current Evidence ◽  
Initial Description ◽  
Relationship Of ◽  
Inflammatory Syndrome ◽  
The Relationship

Background: Since its initial description in December 2019 in Wuhan, China, coronavirus disease 2019 (COVID-19) has rapidly progressed into a worldwide pandemic, which has affected millions of lives. Unlike the disease in adults, the vast majority of children with COVID-19 have mild symptoms and are largely spared from severe respiratory disease. However, thereare children who have significant respiratory disease, and some may develop a hyperinflammatory response similar to thatseen in adults with COVID-19 and in children with Kawasaki disease (KD), which has been termed multisystem inflammatory syndrome in children (MIS-C).Objective: The purpose of this report was to examine the current evidence that supports the etiopathogenesis of COVID-19 in children and the relationship of COVID-19 with KD and MIS-C as a basis for a better understanding of the clinical course, diagnosis, and management of these clinically perplexing conditions.Results: The pathogenesis of COVID-19 is carried out in two distinct but overlapping phases of COVID-19: the first triggered by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) itself and the second by the host immune response. Children with KD have fewer of the previously described COVID-19–associated KD features with less prominent acute respiratory distress syndrome and shock than children with MIS-C.Conclusion: COVID-19 in adults usually includes severe respiratory symptoms and pathology, with a high mortality. Ithas become apparent that children are infected as easily as adults but are more often asymptomatic and have milder diseasebecause of their immature immune systems. Although children are largely spared from severe respiratory disease, they canpresent with a SARS-CoV-2–associated MIS-C similar to KD.

Editor's Note

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Emily Kaliel
Keyword(s):  
Civil War ◽  
Public Memory ◽  
Historical Memory ◽  
Historical Analysis ◽  
Red River ◽  
Cultural Institutions ◽  
Economic Rights ◽  
The Past ◽  
Relationship Of

The articles published in our Fall 2016 edition are connected loosely under the themes of public memory and the uses of identity in the past. We are thrilled to present to you three excellent articles in our Fall 2016 edition: The article "Dentro de la Revolución: Mobilizing the Artist in Alfredo Sosa Bravo's Libertad, Cultura, Igualdad (1961)" analyzes Cuban artwork as multi-layered work of propaganda whose conditions of creation, content, and exhibition reinforce a relationship of collaboration between artists and the state-run cultural institutions of post-revolutionary Cuba; moving through fifty years of history “’I Shall Never Forget’: The Civil War in American Historical Memory, 1863-1915" provides a captivating look at the role of reconciliationist and emancipationist intellectuals, politicians, and organizations as they contested and shaped the enduring memory of the Civil War; and finally, the article “Politics as Metis Ethnogenesis in Red River: Instrumental Ethnogenesis in the 1830s and 1840s in Red River” takes the reader through a historical analysis of the development of the Metis identity as a means to further their economic rights. We wholly hope you enjoy our Fall 2016 edition as much as our staff has enjoyed curating it. Editors  Jean Middleton and Emily Kaliel Assistant Editors Magie Aiken and Hannah Rudderham Senior Reviewers Emily Tran Connor Thompson Callum McDonald James Matiko Bronte Wells

IV.—The Geological Development, Descent and Distribution of the Mammalia

1893 ◽  
Vol 10 (9) ◽  
pp. 401-412 ◽  
Author(s):  
Karl A. von Zittel
Keyword(s):  
South America ◽  
The Past ◽  
Limited Experience ◽  
The World ◽  
Relationship Of ◽  
North And South America ◽  
The Relationship ◽  
North And South ◽  
Animal World

In a spirited treatise on the ‘Origin of our Animal World’ Prof. L. Rütimeyer, in the year 1867, described the geological development and distribution of the mammalia, and the relationship of the different faunas of the past with each other and with that now existing. Although, since the appearance of that masterly sketch the palæontological material has been, at least, doubled through new discoveries in Europe and more especially in North and South America, this unexpected increase has in most instances only served as a confirmation of the views which Rutimeyer advanced on more limited experience. At present, Africa forms the only great gap in our knowledge of the fossil mammalia; all the remaining parts of the world can show materials more or less abundantly, from which the course followed by the mammalia in their geological development can be traced with approximate certainty.

Two way relationship of pregnancy and immune responses to infectious diseases

Placenta ◽  
1996 ◽  
Vol 17 (5-6) ◽  
pp. A10
Author(s):  
L. Krishnan ◽  
L.J. Guilbert ◽  
T.G. Wegmann ◽  
M. Belosevic ◽  
T.R. Mosmann
Keyword(s):  
Infectious Diseases ◽  
Immune Responses ◽  
Relationship Of

scholarly journals A review on the production, structure, bioactivities and applications of Tremella polysaccharides

2021 ◽  
Vol 35 ◽  
pp. 205873842110005
Author(s):  
Xia Ma ◽  
Meng Yang ◽  
Yan He ◽  
Chuntao Zhai ◽  
Chengliang Li
Keyword(s):  
Biologically Active ◽  
Research Progress ◽  
Research Trend ◽  
Production Structure ◽  
Health States ◽  
Preparation Methods ◽  
The Past ◽  
Structure Activity ◽  
Relationship Of ◽  
Active Natural

Tremella polysaccharide is known to be structurally unique and biologically active natural products, abundant and versatile in activities and applications in food industry, daily chemical industry and medicine industry. In order to improve the industrialisation of Tremella polysaccharide, the limitations of preparation and structure-activity relationship of Tremella polysaccharide were reviewed in this paper. The research progress of Tremella polysaccharide in the past 20 years was summarized from the sources, preparation methods, molecular structure, activity and application, and the research trend in the future was also prospected. The application prospect of Tremella polysaccharide in against multiple sub-health states was worth expecting.

scholarly journals The relationship of insight with psychopathological dimensions in patients with schizophrenia

2021 ◽  
Vol 12 (2) ◽  
pp. 204380872110199
Author(s):  
Si-Sheng Huang ◽  
Cheng-Chen Chang
Keyword(s):  
Medical Center ◽  
Self Report ◽  
Psychiatric Ward ◽  
Neurocognitive Functions ◽  
Bivariate Correlation ◽  
Syndrome Scale ◽  
Acute Psychiatric Ward ◽  
Negative Syndrome ◽  
Relationship Of ◽  
The Relationship

Impaired insight in patients with schizophrenia results in less satisfactory clinical outcomes. This study was conducted to investigate the relationship between insight and individual psychopathological dimensions in inpatients with schizophrenia using a self-report questionnaire. In this study, 90 patients with schizophrenia aged 18–75 years admitted in the acute psychiatric ward of a medical center in Taiwan were enrolled. Patient insight was measured using the Self-Appraisal of Illness Questionnaire (SAIQ), and psychopathological dimensions were measured using the Positive and Negative Syndrome Scale (PANSS) and its five-factor structure model. A higher SAIQ score indicates greater insight. In bivariate correlation analyses, statistically significant correlations were observed between age, single marital status, educational level, and positive, excited, and depressed symptom factor of the PANSS and SAIQ score. In regression analyses, age and excited and depressed symptom factors were significantly associated with SAIQ score. No significant association was observed between insight and neurocognitive functions. Considering demographic characteristics, psychopathology, and neurocognition, in the acute phase of schizophrenia, younger patients with less severe excited symptoms and more severe depressive symptoms had greater insight.

scholarly journals MicroRNAs: Biological Regulators in Pathogen–Host Interactions

Cells ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 113 ◽  
Author(s):  
Stephanie Maia Acuña ◽  
Lucile Maria Floeter-Winter ◽  
Sandra Marcia Muxel
Keyword(s):  
Immune Response ◽  
Infectious Diseases ◽  
Small Rnas ◽  
Immune Cell ◽  
Fine Tuning ◽  
Biological Processes ◽  
Host Interactions ◽  
The Past ◽  
Biological Aspects

An inflammatory response is essential for combating invading pathogens. Several effector components, as well as immune cell populations, are involved in mounting an immune response, thereby destroying pathogenic organisms such as bacteria, fungi, viruses, and parasites. In the past decade, microRNAs (miRNAs), a group of noncoding small RNAs, have emerged as functionally significant regulatory molecules with the significant capability of fine-tuning biological processes. The important role of miRNAs in inflammation and immune responses is highlighted by studies in which the regulation of miRNAs in the host was shown to be related to infectious diseases and associated with the eradication or susceptibility of the infection. Here, we review the biological aspects of microRNAs, focusing on their roles as regulators of gene expression during pathogen–host interactions and their implications in the immune response against Leishmania, Trypanosoma, Toxoplasma, and Plasmodium infectious diseases.

scholarly journals Cardiorespiratory Functioning in Youth with Persistent Post-Concussion Symptoms: A Pilot Study

2021 ◽  
Vol 10 (4) ◽  
pp. 561
Author(s):  
Aliyah Snyder ◽  
Christopher Sheridan ◽  
Alexandra Tanner ◽  
Kevin Bickart ◽  
Molly Sullan ◽  
...  
Keyword(s):  
Processing Speed ◽  
Mean Value ◽  
Exhaled Breath ◽  
Post Injury ◽  
The Past ◽  
Neurobehavioral Outcomes ◽  
End Tidal ◽  
Relationship Of ◽  
The Relationship ◽  
End Tidal Co2

Dysregulation of the autonomic nervous system (ANS) may play an important role in the development and maintenance of persistent post-concussive symptoms (PPCS). Post-injury breathing dysfunction, which is influenced by the ANS, has not been well-studied in youth. This study evaluated cardiorespiratory functioning at baseline in youth patients with PPCS and examined the relationship of cardiorespiratory variables with neurobehavioral outcomes. Participants were between the ages of 13–25 in two groups: (1) Patients with PPCS (concussion within the past 2–16 months; n = 13) and (2) non-injured controls (n = 12). Capnometry was used to obtain end-tidal CO2 (EtCO2), oxygen saturation (SaO2), respiration rate (RR), and pulse rate (PR) at seated rest. PPCS participants exhibited a reduced mean value of EtCO2 in exhaled breath (M = 36.3 mmHg, SD = 2.86 mmHg) and an altered inter-correlation between EtCO2 and RR compared to controls. Neurobehavioral outcomes including depression, severity of self-reported concussion symptoms, cognitive catastrophizing, and psychomotor processing speed were correlated with cardiorespiratory variables when the groups were combined. Overall, results from this study suggest that breathing dynamics may be altered in youth with PPCS and that cardiorespiratory outcomes could be related to a dimension of neurobehavioral outcomes associated with poorer recovery from concussion.

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