scholarly journals Better dietary adherence and weight maintenance achieved by a long-term moderate-fat diet

2007 ◽  
Vol 97 (2) ◽  
pp. 399-404 ◽  
Author(s):  
Leila Azadbakht ◽  
Parvin Mirmiran ◽  
Ahmad Esmaillzadeh ◽  
Fereidoun Azizi
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Weight Maintenance ◽  
Low Fat ◽  
Low Fat Diet

The objective of the present study was to determine the effects of a long-term moderate-fat diet (30 % energy from fat)v.a low-fat one (20 % energy from fat) on metabolic risks. The study was a randomised, prospective 14-month trial on overweight and obese patients (eighty-nine overweight and obese men and women). The intervention was a moderate-fat diet (30 % energy) or a low-fat diet (20 % energy). The main outcome measurements were change in body weight, waist circumference, LDL-cholesterol, HDL-cholesterol, total cholesterol, TAG, and systolic and diastolic blood pressure. Forty-five subjects on the moderate-fat diet and forty-four subjects on the low-fat one were studied. Characteristics of all randomised participants were similar in both groups. After 7 months, the moderate- and low-fat diets had similar effects on cardiovascular risks. The moderate-fat diet was more successful after 14 months in reducing weight ( − 5·0 (sd2·5) kg in the moderate-fat groupv.− 1·2 (sd1·1) kg in the low-fat one;P < 0·0001), waist circumference ( − 5·5 (sd2·4) cm in the moderate-fat groupv.− 2·3 (sd1·3) cm in the low-fat one;P < 0·0001), and other cardiovascular risk factors as well (LDL, TAG, total cholesterol and systolic blood pressure). In conclusion, a moderate-fat energy-restricted diet in the long term might have more beneficial effects on weight maintenance and cardiovascular risk factors compared with a low-fat diet. Better dietary adherence with the moderate-fat diet may be the reason for its successful effects.

Long-term effects (>24 months) of multiple lifestyle intervention on major cardiovascular risk factors among high risk subjects: a meta-analysis

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
H Bergum ◽  
I Sandven ◽  
TO Klemsdal
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Lifestyle Intervention ◽  
Small Study ◽  
Long Term Effects

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Norwegian health department Background The evidence of the long-term effects of multiple lifestyle intervention on cardiovascular risk is uncertain. We aimed to summarize the evidence from randomized clinical trials examining the efficacy of lifestyle intervention on major cardiovascular risk factors in subjects at high cardiovascular risk. Methods  Eligible trials investigated the impact of lifestyle intervention versus usual care with minimum 24 months follow-up, reporting more than one major cardiovascular risk factor. A literature search updated April 15, 2020 identified 12 eligible studies. The results from individual trials were combined using fixed and random effect models, using the standardized mean difference (SMD) to estimate effect sizes. Small-study effect was evaluated, and heterogeneity between studies examined by subgroup and meta-regression analyses considering patient- and study-level variables. Results  Small-study effect was not identified. Lifestyle intervention reduced systolic blood pressure modestly with an estimated SMD of -0.13, 95% confidence interval (CI): -0.21 to -0.04, with moderate heterogeneity (I² = 59%), corresponding to a mean difference of approximately 2 mmHg (MD = -1.86, 95% CI: -3.14 to -0.57, p = 0.0046). This effect disappeared in the subgroup of trials judged at low risk of bias (SMD = 0.02, 95% CI: -0.08 to 0.11). For the outcome total cholesterol SMD was -0.06, 95% CI: -0.13 to 0.00, with no heterogeneity (I² = 0%), indicating no effect of the intervention. Conclusion  Lifestyle intervention resulted in only a modest effect on systolic blood pressure and no effect on total cholesterol after 24 months. Further lifestyle trials should consider the challenge of maintaining larger long-term benefits to ensure impact on cardiovascular outcomes.

scholarly journals Long-term effects (> 24 months) of multiple lifestyle intervention on major cardiovascular risk factors among high-risk subjects: a meta-analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hilde Bergum ◽  
Irene Sandven ◽  
Tor Ole Klemsdal
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Lifestyle Intervention ◽  
Small Study ◽  
Long Term Effects

Abstract Background The evidence of the long-term effects of multiple lifestyle intervention on cardiovascular risk is uncertain. We aimed to summarize the evidence from randomized clinical trials examining the efficacy of lifestyle intervention on major cardiovascular risk factors in subjects at high cardiovascular risk. Methods Eligible trials investigated the impact of lifestyle intervention versus usual care with minimum 24 months follow-up, reporting more than one major cardiovascular risk factor. A literature search updated April 15, 2020 identified 12 eligible studies. The results from individual trials were combined, using fixed and random effect models, using the standardized mean difference (SMD) to estimate effect sizes. Small-study effect was evaluated, and heterogeneity between studies examined, by subgroup and meta-regression analyses, considering patient- and study-level variables. Results Small-study effect was not identified. Lifestyle intervention reduced systolic blood pressure modestly with an estimated SMD of − 0.13, 95% confidence interval (CI): − 0.21 to − 0.04, with moderate heterogeneity (I2 = 59%), corresponding to a mean difference of approximately 2 mmHg (MD = − 1.86, 95% CI − 3.14 to − 0.57, p = 0.0046). This effect disappeared in the subgroup of trials judged at low risk of bias (SMD = 0.02, 95% CI − 0.08 to 0.11). For the outcome total cholesterol SMD was − 0.06, 95% CI − 0.13 to 0.00, with no heterogeneity (I2 = 0%), indicating no effect of the intervention. Conclusion Lifestyle intervention resulted in only a modest effect on systolic blood pressure and no effect on total cholesterol after 24 months. Further lifestyle trials should consider the challenge of maintaining larger long-term benefits to ensure impact on cardiovascular outcomes.

scholarly journals Examining associations between dietary patterns and metabolic CVD risk factors: a novel use of structural equation modelling

2016 ◽  
Vol 115 (9) ◽  
pp. 1586-1597 ◽  
Author(s):  
Michelle Alessandra Castro ◽  
Valéria Troncoso Baltar ◽  
Dirce Maria Marchioni ◽  
Regina Mara Fisberg
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Body Weight ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Cardiovascular Risk Factors ◽  
Dietary Patterns ◽  
Structural Equation ◽  
Cholesterol Ratio ◽  
Equation Modelling

AbstractThe association between dietary patterns and metabolic cardiovascular risk factors has long been addressed but there is a lack of evidence towards the effects of the overall diet on the complex net of biological inter-relationships between risk factors. This study aimed to derive dietary patterns and examine their associations with metabolic cardiovascular risk factors following a theoretic model for the relationship between them. Participants included 417 adults of both sexes, enrolled to the cross-sectional population-based study performed in Brazil. Body weight, waist circumference, high-sensitivity C-reactive protein, blood pressure, total cholesterol:HDL-cholesterol ratio, TAG:HDL-cholesterol ratio, fasting plasma glucose and serum leptin were evaluated. Food consumption was assessed by two non-consecutive 24-h dietary recalls adjusted for the within-person variation of intake. A total of three dietary patterns were derived by exploratory structural equation modelling: ‘Traditional’, ‘Prudent’ and ‘Modern’. The ‘Traditional’ pattern had a negative and direct effect on obesity indicators (serum LEP, body weight and waist circumference) and negative indirect effects on total cholesterol:HDL-cholesterol ratio, TAG:HDL-cholesterol ratio and fasting plasma glucose. The ‘Prudent’ pattern had a negative and direct effect on systolic blood pressure. No association was observed for the ‘Modern’ pattern and metabolic risk factors. In conclusion, the ‘Traditional’ and ‘Prudent’ dietary patterns were negatively associated with metabolic cardiovascular risk factors among Brazilian adults. Their apparent protective effects against obesity and high blood pressure may be important non-pharmacological strategies for the prevention and control of obesity-related metabolic disorders and CVD.

Associations of Cardiorespiratory Fitness and Fatness With Cardiovascular Risk Factors Among Adolescents: The NHANES 1999–2002

2010 ◽  
Vol 7 (6) ◽  
pp. 746-753 ◽  
Author(s):  
Soyang Kwon ◽  
Trudy L. Burns ◽  
Kathleen Janz
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Cardiorespiratory Fitness ◽  
Lipid Profiles ◽  
Insulin Metabolism ◽  
Fitness Level ◽  
Adjusted Means

Background:This study aimed to examine combined and independent effects of cardiorespiratory fitness and fatness on cardiovascular risk factors among U.S. adolescents.Methods:Data from adolescents age 12 to 19 years participating in the NHANES 1999 to 2002 were used. Fitness level was determined by submaximal treadmill test and was dichotomized as ‘not fit’ or ‘fit’ according to the FITNESSGRAM. Fatness level was categorized as ‘not fat’ or ‘fat’ based on the CDC BMI growth charts. Gender-specific multivariable linear regression analyses were conducted to compare age-, race/ethnicity-, fatness-, and waist circumference-adjusted means of blood pressure, lipids, lipoproteins, C-peptide, insulin, and C-reactive protein (CRP) levels.Results:A total of 3202 adolescents (1629 boys) were included for data analysis. Among boys, total cholesterol, tri-glycerides, insulin, and CRP mean levels were significantly higher (P < .05) in the ‘not fit’ group than in the ‘fit’ group, after adjustment for fatness level and waist circumference. Among girls, the fatness level- and waist circumference-adjusted means of total cholesterol (P < .01) and LDL-C (P < .09) were higher in the ‘not fit’ than ‘fit’ groups.Conclusion:Cardiorespiratory fitness, independent of fatness, may have beneficial effects on lipid profiles among girls, and on lipid profiles, insulin metabolism, and inflammation levels among boys.

scholarly journals Effects of Weight Loss and Long-Term Weight Maintenance With Diets Varying in Protein and Glycemic Index on Cardiovascular Risk Factors

Circulation ◽  
2011 ◽  
Vol 124 (25) ◽  
pp. 2829-2838 ◽  
Author(s):  
Özlem Gögebakan ◽  
Angela Kohl ◽  
Martin A. Osterhoff ◽  
Marleen A. van Baak ◽  
Susan A. Jebb ◽  
...  
Keyword(s):  
Risk Factors ◽  
Weight Loss ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Glycemic Index ◽  
Weight Maintenance

scholarly journals THE RELATIONSHIP BETWEEN DAILY STEPS AND CARDIOVASCULAR RISK FACTORS AMONG TEACHERS IN CENTRAL REGION, MALAYSIA

2020 ◽  
Vol 9 (2) ◽  
Author(s):  
Shafiqah Mohd Radhi ◽  
Nur Zakiah Mohd Saat ◽  
Nor Farah Mohamad Fauzi ◽  
Siti Aishah Hanawi
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Cardiovascular Risk Factors ◽  
Diastolic Blood Pressure ◽  
Blood Sugar ◽  
School Teachers ◽  
Steps Per Day

Physical activity is an important component of cardiovascular health. The fact that physical activity is also associated with a substantial number of cognitive and academic benefits, therefore schools teachers can be an important role model in promoting a physically-active lifestyle in school children. The aim of this study is to examine the levels of physical activity (PA) and its association with cardiovascular risk factors in a sample of school teachers. Forty-nine (n=49) teachers from primary and secondary schools around Klang Valley urban areas were recruited. The PA level was determined using pedometer, worn for three consecutive days. Anthropometric measurements and blood samples were collected to determine cardiovascular risk factors. Findings showed that the school teachers recorded an overall mean (± SEM) of 7707 ± 490 steps/day, which is below the recommended target of 10 000 steps per day. According to pedometer-determined physical activity indices proposed by Tudor-Locke and Bassett (2004), 20.83% of the sample were classified as ‘sedentary’ (<5000 steps/day), 35.40% were ‘low active’ (5000 – 7499 steps/day) and only 18.70% achieved more than 10 000 steps/day. According to Asian BMI cut-off points, 43% of the teachers were categorized as overweight and obese (>23 kg/m2). The mean values for waist circumference, fasting blood sugar, and cholesterol level, systolic and diastolic blood pressure were 83.96 ± 1.90 cm, 5.41 ± 0.26 mmol/l, 4.64±0.26 mmol/l, 118.90 ± 1.72 mmHg and 72.40±1.58 mmHg respectively. Fisher Exact Test shown that there were significant association between daily step and age category. Daily steps weakly negative correlated with systolic blood pressure (r = -0.024, p > 0.05) as well as blood sugar levels (r = -0.061, p> 0.05), diastolic blood pressure (r = -0.079, p> 0.05), body mass index (r = -0.271, p> 0.05), waist circumference (r = -0.196, p> 0.05), as well as blood cholesterol levels (r = -0.037, p> 0.05). In conclusion, there were weak negative correlations between steps per day and cardiovascular risk factors. Generally, the level of physical activity in the sample of teachers needs to be improved. Interventions aimed at promoting PA among school teachers may be warranted in the future.

Evaluation of Waist Circumference to Predict Cardiovascular Risk Factors in an Overweight Tehranian Population: Findings from Tehran Lipid and Glucose Study

2005 ◽  
Vol 75 (5) ◽  
pp. 347-356 ◽  
Author(s):  
Esmaillzadeh ◽  
Mirmiran ◽  
Azizi
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Cardiovascular Risk Factors ◽  
Age Groups ◽  
Anthropometric Measures ◽  
Predictive Values ◽  
Biochemical Analyses ◽  
Adequate Evidence

This study was conducted to evaluate the waist circumference (WC) cut-off points to predict cardiovascular risk factors in the overweight Tehranian population. Anthropometric measures, blood pressure, and biochemical analyses were evaluated for the 15,005 participants of the Tehran Lipid and Glucose Study. Three thousand sixty-five subjects aged 18–74 years with a body mass index of 25–29.9 were enrolled in this study. Abdominal obesity was defined as WC ≥ 102 cm for men and ≥ 88 cm for women. Sensitivity of WC ≥ 102 cm to detect various cardiovascular risk factors for men aged 35–54 years was between 5% and 14%, and for men aged 55–74 years, was between 12% and 19%. The specificity of this cut-off point was between 93% and 98% and between 86% and 96% for corresponding age-categories, respectively. WC ≥ 88 cm had a sensitivity of between 28% and 41% for identifying cardiovascular risk factors in women aged 18–34 years. Sensitivity tended to increase with age and specificity tended to decrease with age in both genders. These cut-off points had the highest positive predictive value for the more prevalent risk factors in both genders. The negative predictive values were different for various risk factors among age groups. The classic cut-off points of WC failed to provide adequate evidence for the use of WC in detecting cardiovascular risk factors. Further studies should be conducted to determine optimal WC cut-off points for Iranians.

Abstract P387: Cardiovascular Risk Factors Among Children in a 20 year Community Study: Influence of the Family

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Tracy L Nelson ◽  
Laura Dvorak ◽  
Kathy Kioussopoulos ◽  
Gary Luckasen
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Total Cholesterol ◽  
Cardiovascular Risk Factors ◽  
Family Member ◽  
High Blood Pressure ◽  
High Cholesterol ◽  
Northern Colorado ◽  
The Family

Background: High cholesterol, atherosclerosis, high blood pressure, and obesity can be identified during childhood. Identifying the underlying contributors to such risk factors may allow young families the opportunity to modify health habits. The purpose of this study was to determine the prevalence of cardiovascular risk factors and their associated predictors among Northern Colorado children and their families. Methods: The Poudre Valley Health System (PVHS), Healthy Hearts Club has provided a successful cardiovascular screening program for the past ∼20 years (1993–2011) to identify risk factors among students in six Northern Colorado school districts (a primarily white population ∼90%). Schools were selected based on willingness to participate. Data were collected cross-sectionally with objective measures of total cholesterol, high-density lipoprotein cholesterol (HDL-C), blood pressure and body mass index (BMI). Surveys were filled out by the parent and/or legal guardian and included questions about diet and physical activity of the child as well as these behaviors and risk factors among family members. Results: There were 9,363 children with information for the measured risk factors (mean age, 10.4 years, range, 6.2–18 years, 49% female). The prevalence of the six measured risk factors included 39% with total cholesterol > 170 mg/dl, 10.7%, with HDL-C < 35 mg/dl, 11.7% with Cholesterol/HDL ratio >4.8, 7.2% with systolic blood pressure > 120 mmHg, 8.2% with diastolic blood pressure > 80 mmHg and 21.1% with BMI > 85 percentile for age and sex. There were 40.8%, 35%, 14.5%, 6.2%, 2.4%, 0.8% and 0.2% with 0–6 risk factors respectively. Of those with zero risk factors 25.7% reported a family member (other than the child) being overweight while 68.2% reported such among those with five risk factors; similarly 16.4% reported a family member who smokes (among children with zero risk factors) as compared to 24% with five risk factors. High cholesterol, high blood pressure and diabetes trended similar. Conclusions: The prevalence of CVD risk factors among these children is substantial and is associated with such risk factors among the family. This data suggests risk factor reduction must not be done in isolation of the family.

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