The effect of 12 weeks of euenergetic high-protein diet in regulating appetite and body composition of women with normal-weight obesity: a randomised controlled trial

AbstractNormal-weight obesity (NWO) syndrome is associated with metabolic diseases. The present study aimed to investigate the effects of 12 weeks of a high-protein (HP) v. a standard protein (SP) diet on appetite, anthropometry and body composition in NWO women. In this clinical trial, fifty NWO women were randomly allocated to HP (n 25) or SP (n 25) diet groups. Women in the HP and SP groups consumed 25 and 15 % of their total energy intake from protein for 12 weeks. Weight, fat mass (FM), lean body mass (LBM), waist circumference (WC) and appetite were evaluated at baseline and following their 3-month intervention. After 12 weeks, the LBM was higher in HP compared with no significant changes in the SP group (mean between-group difference = 1·5 kg; 95 % CI 3·1, 0·01; effect size (d) = 0·4). Furthermore, the HP group had lower FM (mean between-group difference –1·1 kg; 95 % CI 1, –3·3; d = –0·2), body fat percentage (BFP) (mean between-group difference –2 %; 95 % CI 0·7, –5·2; d = –0·3) and WC (mean between-group difference –1·4 cm; 95 % CI 0·6, –3·6; d = –0·2) at the end of the study in comparison with the SP group. In both groups, weight and appetite were unchanged over time without significant differences between groups. Twelve weeks of euenergetic diets with different dietary protein contents resulted in no significant weight loss in women with NWO. However, an HP diet significantly improved body composition (LBM, FM, BFP and WC) in this population.

Download Full-text

A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial

Diabetologia ◽

10.1007/s00125-019-4956-4 ◽

2019 ◽

Vol 62 (11) ◽

pp. 2066-2078 ◽

Cited By ~ 20

Author(s):

Mads J. Skytte ◽

Amirsalar Samkani ◽

Amy D. Petersen ◽

Mads N. Thomsen ◽

Arne Astrup ◽

...

Keyword(s):

Type 2 Diabetes ◽

Randomised Controlled Trial ◽

Controlled Trial ◽

High Protein Diet ◽

Fat Content ◽

Protein Diet ◽

Liver Fat ◽

Liver Fat Content ◽

Randomised Controlled

Download Full-text

The Effects of a High-Protein Diet on Bone Mineral Density in Exercise-Trained Women: A 1-Year Investigation

Journal of Functional Morphology and Kinesiology ◽

10.3390/jfmk3040062 ◽

2018 ◽

Vol 3 (4) ◽

pp. 62

Author(s):

Jose Antonio ◽

Anya Ellerbroek ◽

Cassandra Carson

Keyword(s):

Bone Mineral Density ◽

Body Composition ◽

Bone Mineral ◽

Mineral Content ◽

High Protein Diet ◽

High Protein ◽

Protein Diet ◽

Whole Body ◽

Mineral Density ◽

One Year

The effects of long-term high-protein consumption (i.e., >2.2 g/kg/day) are unclear as it relates to bone mineral content. Thus, the primary endpoint of this investigation was to determine if consuming a high-protein diet for one year affected various parameters of body composition in exercise-trained women. This investigation is a follow-up to a prior 6-month study. Subjects were instructed to consume a high-protein diet (>2.2 g/kg/day) for one year. Body composition was assessed via dual-energy X-ray absorptiometry (DXA). Subjects were instructed to keep a food diary (i.e., log their food ~three days per week for a year) via the mobile app MyFitnessPal®. Furthermore, a subset of subjects had their blood analyzed (i.e., basic metabolic panel). Subjects consumed a high-protein diet for one year (mean ± SD: 2.3 ± 1.1 grams per kilogram body weight daily [g/kg/day]). There were no significant changes for any measure of body composition over the course of the year (i.e., body weight, fat mass, lean body mass, percent fat, whole body bone mineral content, whole body T-score, whole body bone mineral density, lumbar bone mineral content, lumbar bone mineral density and lumbar T-score). In addition, we found no adverse effects on kidney function. Based on this 1-year within-subjects investigation, it is evident that a diet high in protein has no adverse effects on bone mineral density or kidney function.

Download Full-text

The PROMOTE study (High-protein and resistance-training combination in overweight and obesity) for short-term weight loss and long-term weight maintenance for Chinese people: a protocol for a pilot randomized controlled trial

Trials ◽

10.1186/s13063-019-3954-7 ◽

2020 ◽

Vol 21 (1) ◽

Cited By ~ 1

Author(s):

Shaoyong Xu ◽

Juan Zhang ◽

Yuxiang Dong ◽

Ruikun Chen ◽

Wenlei Xu ◽

...

Keyword(s):

Weight Loss ◽

Resistance Training ◽

Controlled Trial ◽

Weight Maintenance ◽

High Protein Diet ◽

Diet Group ◽

High Protein ◽

Protein Diet ◽

Short Term ◽

Low Fat Diet

Abstract Background It is very important for clinicians and dieticians to explore reasonable weight management strategies for obese people that address both short-term weight loss and subsequent weight maintenance. We hypothesized that resistance training combined with a high-protein diet would result in similar short-term weight loss but better long-term weight maintenance than either a conventional low-fat diet control or a high-protein diet alone. Methods/design This is an 8-week randomized parallel controlled trial followed by a 24-week observational follow-up study. A 48-week supplementary follow-up study will be carried out if necessary. The study will be conducted between June 2019 and October 2020. The 90 overweight or obese participants will be randomly assigned to the conventional low-fat diet group, the high-protein diet group and the high-protein diet and resistance training combination group. Primary outcomes are body weight change at week 8 and week 24 compared with the baseline level. Discussion High-quality research on the effect of a high-protein diet combined resistance training on weight loss and weight maintenance is limited in the Chinese population. Our study will provide a basis for obesity management in China and will promote the development of exercise- and diet-related studies. Trial registration Chinese Clinical Trial Registry, ChiCTR1900023841. Registered on 14 June 2019.

Download Full-text

The effect of choice feeding during the rearing period on reproductive function in the gilt

Proceedings of the British Society of Animal Science ◽

10.1017/s1752756200001034 ◽

2000 ◽

Vol 2000 ◽

pp. 102-102 ◽

Cited By ~ 1

Author(s):

S. R. L. Lucas ◽

J. A. Rooke ◽

V. C. Bland ◽

A.G. Sinclair ◽

S. A. Edwards

Keyword(s):

Body Composition ◽

Reproductive Function ◽

High Protein Diet ◽

Diet Selection ◽

Growing Pigs ◽

High Protein ◽

Protein Source ◽

Protein Diet ◽

Choice Feeding ◽

Growth And Reproduction

Previous studies (e.g. Cia et al. 1998) have shown that modification of body composition of the prepubertal gilt has effects on responsiveness of gilts to exogenous gonadotrophin. Growing pigs are able to select a diet from different foods differing in protein:energy ratio (Dalby 1998); however there is little evidence of what effect the conflicting nutritional demands of growth and reproduction have on diet selection. The objectives of the experiment were to quantify the effects of choice feeding on responsiveness of gilts to exogenous gonadotrophin (Cia et al. 1998) and to investigate the effect of protein source on diet selection as Jones et al.(2000) have observed selection by breeding gilts against a high protein diet containing fishmeal.

Download Full-text