Survival of the 8.5 mm osseointegrated abutment, and its utility in the obese patient

AbstractBackground:Most of the literature regarding osseointegrated implantation for hearing rehabilitation focuses on the 5.5 mm abutment. This study aimed to add to the data available on the survival of the 8.5 mm abutment, and to describe its utility in obese patients.Objective:To review the outcomes of patients who received a bone-anchored hearing aid implant, and create a model comparing the mechanical forces acting upon combinations of fixture and abutment lengths.Methods:Retrospective chart review and mathematical modelling.Results:In this retrospective cohort study comprising 25 patients, less abutment overgrowth was observed in the 8.5 mm abutment recipients versus recipients of the 5.5 mm abutment. When the principle of equilibrium of a rigid body was applied, the 8.5 mm abutment was at a calculated mechanical disadvantage compared with the 5.5 mm abutment.Conclusion:The 8.5 mm abutment may be useful in patients with copious subcutaneous soft tissue as in the obese population. The 8.5 mm abutment has a calculated mechanical disadvantage, potentially putting the implant under greater mechanical stress; however, the clinical relevance of this is unclear.

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Mortality among patients with sepsis associated with a bispectral electroencephalography (BSEEG) score

Scientific Reports ◽

10.1038/s41598-021-93588-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Takehiko Yamanashi ◽

Pedro S. Marra ◽

Kaitlyn J. Crutchley ◽

Nadia E. Wahba ◽

Johnny R. Malicoat ◽

...

Keyword(s):

Cohort Study ◽

Patient Outcomes ◽

Retrospective Cohort ◽

Chart Review ◽

Retrospective Chart Review ◽

Mortality Data ◽

Single Center ◽

Significant Difference ◽

The Relationship ◽

Potential Tool

AbstractWe have previously developed a bispectral electroencephalography (BSEEG) device, which was shown to be effective in detecting delirium and predicting patient outcomes. In this study we aimed to apply the BSEEG approach for a sepsis. This was a retrospective cohort study conducted at a single center. Sepsis-positive cases were identified based on retrospective chart review. EEG raw data and calculated BSEEG scores were obtained in the previous studies. The relationship between BSEEG scores and sepsis was analyzed, as well as the relationship among sepsis, BSEEG score, and mortality. Data were analyzed from 628 patients. The BSEEG score from the first encounter (1st BSEEG) showed a significant difference between patients with and without sepsis (p = 0.0062), although AUC was very small indicating that it is not suitable for detection purpose. Sepsis patients with high BSEEG scores showed the highest mortality, and non-sepsis patients with low BSEEG scores showed the lowest mortality. Mortality of non-sepsis patients with high BSEEG scores was as bad as that of sepsis patients with low BSEEG scores. Even adjusting for age, gender, comorbidity, and sepsis status, BSEEG remained a significant predictor of mortality (p = 0.008). These data are demonstrating its usefulness as a potential tool for identification of patients at high risk and management of sepsis.

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A retrospective cohort study to assess adjuvant concurrent chemoradiation (CCRT) compared to adjuvant radiation therapy (RT) in the treatment of grade 2 and 3 extremity soft tissue sarcomas

Radiotherapy and Oncology ◽

10.1016/j.radonc.2017.08.037 ◽

2017 ◽

Vol 125 (1) ◽

pp. 160-167 ◽

Cited By ~ 5

Author(s):

Jean Philippe Nesseler ◽

Julia Salleron ◽

Maria Rios ◽

Philippe Nickers ◽

Frederic Marchal ◽

...

Keyword(s):

Radiation Therapy ◽

Cohort Study ◽

Soft Tissue ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Soft Tissue Sarcomas ◽

Concurrent Chemoradiation ◽

Adjuvant Radiation ◽

Adjuvant Radiation Therapy

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Abdominal Obesity and Short-term Mortality in Critically Ill Patients with Sepsis: A Retrospective Cohort Study Based on the MIMIC-IV Database

10.21203/rs.3.rs-1040005/v1 ◽

2021 ◽

Author(s):

Zhou Lv ◽

Minglu Gu ◽

Miao Zhou ◽

Yanfei Mao ◽

Lai Jiang

Keyword(s):

Metabolic Syndrome ◽

Cohort Study ◽

Intensive Care ◽

Abdominal Obesity ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Obese Patients ◽

Short Term ◽

Icu Admission ◽

Short Term Mortality

Abstract Purpose: Multiple studies have demonstrated an obesity paradox such that obese septic patients have a lower mortality rate and a relatively favorable prognosis. However, less is known on the association between abdominal obesity and short-term mortality in patients with sepsis. We conducted this study to determine whether the obesity-related survival benefit remains among abdominal obese patients.Methods: A retrospective cohort study was conducted using data derived from the Medical Information Mart for Intensive Care IV database. Septic patients (≥18 years) with or without abdominal obesity of first intensive care units (ICU) admission in the database were enrolled. The primary outcome was mortality within 28 days of ICU admission and multivariable logistic regression analyses were employed to assess any association between abdominal obesity and the outcome variable.Results: A total of 21534 patients were enrolled finally, the crude 28-day mortality benefit after ICU admission was not observed in patients with abdominal obesity (15.8% vs. 15.3%, p=0.32). In the extended multivariable logistic models, the odds ratio (OR) of abdominal obesity was significantly inversed after incorporating metabolic variables into the logistic model (OR range 1.094-2.872, p = 0.02). The subgroup analysis showed interaction effects in impaired fasting blood glucose/diabetes and metabolic syndrome subgroups (P = 0.001 and <0.001, respectively). In the subgroups of blood pressure, high-density lipoprotein cholesterol, and triglyceride level, no interaction was detected in the association between abdominal obesity and mortality. After propensity score matching, 6523 pairs of patients were selected. The mortality significantly higher in the abdominal obesity group (17.0% vs. 14.8%, p = 0.015). Notably, the non-abdominal obese patients were weaned off vasopressors and mechanical ventilation more quickly than those in the abdominal obesity group (vasopressor‑free days on day 28 of 27.0 vs. 26.8, p < 0.001; ventilation-free days on day 28 of 26.7 vs. 25.6, p < 0.001).Conclusion: Abdominal obesity was associated with increased risk of adjusted sepsis-related mortality within 28 days after ICU admission and was partially mediated through metabolic syndrome components.

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Utilization of Alexandrite Laser for Hair Removal in Pediatric Auricular Reconstruction

Otolaryngology ◽

10.1177/01945998211041948 ◽

2021 ◽

pp. 019459982110419

Author(s):

Peng You ◽

Tara L. Rosenberg ◽

Yi-Chun Carol Liu

Keyword(s):

Soft Tissue ◽

Chart Review ◽

Laser System ◽

Retrospective Chart Review ◽

Hair Removal ◽

Procedural Sedation ◽

Alexandrite Laser ◽

Auricular Reconstruction ◽

Laser Hair Removal ◽

Soft Tissue Envelope

Auricular reconstruction with autologous rib cartilage involves using a soft tissue envelope to cover the cartilage framework. In patients with a low hairline, hair-bearing skin may be incorporated on the reconstructed ear, creating a difficult and conspicuous aesthetic problem. A retrospective chart review was conducted to summarize and share the experience of using the Candela GentleMax Pro 755-nm alexandrite laser system (Candela Corp) in children following auricular reconstruction. Nine patients received laser hair removal via the alexandrite laser system with good results. The number of completed sessions ranged from 1 to 5. The procedures were completed without the need for premedication or procedural sedation. Laser hair removal with an alexandrite laser system was safe, fast, and effective. With multistage auricular reconstruction, it was feasible to incorporate laser hair removal between the stages.

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