Sensory dysfunction and quality of life after great auricular nerve sacrifice during parotidectomy: our experience

2015 ◽  
Vol 129 (11) ◽  
pp. 1121-1127 ◽  
Author(s):  
J Galli ◽  
M Pandolfini ◽  
M Rigante ◽  
L Schinaia ◽  
M L Guidi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Neck Region ◽  
Inverse Correlation ◽  
Daily Activities ◽  
Sensory Dysfunction ◽  
Great Auricular Nerve ◽  
Item Quality ◽  
The Impact ◽  
Moderate Inverse Correlation

AbstractObjective:This study aimed to investigate the impact on patients' quality of life of great auricular nerve sacrifice during parotidectomy.Methods:A retrospective review was conducted of 191 consecutive patients who underwent parotidectomy with great auricular nerve sacrifice between 2006 and 2011. Residual sensory dysfunction and its impact on quality of life was analysed using an eight-item quality of life survey.Results:In all, 139 out of 191 patients (72.8 per cent) experienced one or more abnormal sensations in the ear or neck region after surgery. There was a moderate inverse correlation between the number of abnormal sensations and time elapsed since surgery. Moreover, the degree of discomfort correlated significantly with the frequency of symptom occurrence (p< 0.001), duration of the abnormal sensation (p< 0.001) and size of the affected area (p< 0.001).Conclusion:Sacrifice of the great auricular nerve has only a small impact on patient quality of life; their daily activities are not significantly affected.

scholarly journals Improved gastrointestinal profile with diroximel fumarate is associated with a positive impact on quality of life compared with dimethyl fumarate: results from the randomized, double-blind, phase III EVOLVE-MS-2 study

2021 ◽  
Vol 14 ◽  
pp. 175628642199399 ◽  
Author(s):  
Annette Wundes ◽  
Sibyl Wray ◽  
Ralf Gold ◽  
Barry A. Singer ◽  
Elzbieta Jasinska ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Medication Use ◽  
Dimethyl Fumarate ◽  
Daily Activities ◽  
Phase Iii ◽  
Symptomatic Medication ◽  
Gi Symptoms ◽  
Symptom Intensity ◽  
The Impact

Background: Diroximel fumarate (DRF) is a novel oral fumarate approved for relapsing forms of multiple sclerosis (MS). DRF demonstrated significantly improved gastrointestinal (GI) tolerability versus dimethyl fumarate (DMF) with fewer days of Individual Gastrointestinal Symptom and Impact Scale (IGISIS) scores ⩾2, GI adverse events (AEs), and treatment discontinuations due to GI AEs. Our aim was to evaluate the impact of GI tolerability events on quality of life (QoL) for patients with relapsing–remitting MS who received DRF or DMF in EVOLVE-MS-2. Methods: A post hoc analysis was conducted in patients who were enrolled in the randomized, blinded, 5-week, EVOLVE-MS-2 [ClinicalTrials.gov identifier: NCT03093324] study of DRF versus DMF. Patients completed daily IGISIS and Global GISIS (GGISIS) eDiary questionnaires to assess GI symptom intensity and interference with daily activities and work. Results: In total, 504 patients (DRF, n = 253; DMF, n = 251) received study drug and 502 (DRF, n = 253; DMF, n = 249) completed at least one post-baseline questionnaire. With DRF, GI symptoms were less likely to interfere ‘quite a bit’ or ‘extremely’ with regular daily activities [IGISIS: DRF, 9.5% (24/253) versus DMF, 28.9% (72/249)] or work productivity [GGISIS: DRF, 6.1% (10/165) versus DMF, 11.3% (18/159)]. DRF-treated patients had fewer days with ⩾1 h of missed work (DRF, 43 days, n = 20 versus DMF, 88 days, n = 26). DMF-treated patients reported highest GI symptom severity and missed work at week 2–3 shortly after completing the titration period, which coincided with the majority of GI-related treatment discontinuations [58.3% (7/12)]. GI tolerability AEs [DRF, 34.8% (88/253); DMF, 48.2% (121/251)], concomitant symptomatic medication use [DRF, 19.3% (17/88) versus DMF, 30.6% (37/121)], and GI-related discontinuations (DRF, 0.8% versus DMF, 4.8%) were lower with DRF versus DMF. Conclusions: The improved GI tolerability with DRF translated into clinically meaningful benefits to QoL, as patients experienced less impact on daily life and work and required less concomitant symptomatic medication use. Trial registration: [ClinicalTrials.gov identifier: NCT03093324]

scholarly journals Relationship between dental fluorosis and quality of life: a population based study

2005 ◽  
Vol 19 (2) ◽  
pp. 150-155 ◽  
Author(s):  
Edgard Michel-Crosato ◽  
Maria Gabriela Haye Biazevic ◽  
Edgard Crosato
Keyword(s):  
Quality Of Life ◽  
Water Supply ◽  
Dental Fluorosis ◽  
Female Gender ◽  
Population Based ◽  
Daily Activities ◽  
Cross Sectional ◽  
Significance Level ◽  
The Impact

The aim of this study was to verify the prevalence of dental fluorosis in schoolchildren aged 6 to 15 and its possible association with the impacts on their daily activities. This study is observational, cross-sectional and analytical. A total of 513 schoolchildren from the city of Pinheiro Preto, SC, took part in this study. The children were examined by three calibrated dentists, after obtaining a kappa > 0.80. To assess the prevalence of fluorosis, clinical examinations were performed according to the methodology set forth by the 4th edition of the WHO. To assess the impact of fluorosis on their daily activities, a modified OIDP (Oral Impacts on Daily Performance) was adopted. The statistical analysis used was the Chi-squared test with a 5% significance level. Of the total number of children examined, 262 (51.1%) were of the female gender and 251 (48.9%) were of the male gender. In regard to the prevalence of fluorosis, 94 (18.3%) of the children presented this condition, while 419 children (81.7%) presented a normal condition. In regard to the severity of fluorosis, few children presented severe alterations. No association was found between dental fluorosis and gender (p = 0.646), between fluorosis and socioeconomic status (p = 0.848) or between fluorosis and access to public water supply system (p = 0.198). The activities that most affected children's daily performance were: oral hygiene (40.9%) and food intake or enjoying food (40.4%). None of the daily activities could be associated with the occurrence of dental fluorosis. The prevalence of dental fluorosis was consonant with the standards found for locations with optimum fluoride content in the water supply. The questionable and very slight levels of fluorosis were the most frequently found, without influence in the quality of life of the schoolchildren participating in the study.

scholarly journals Pulmonary rehabilitation and tuberculosis: a new approach for an old disease

Pneumologia ◽  
2019 ◽  
Vol 68 (3) ◽  
pp. 107-113
Author(s):  
Beatrice Mahler ◽  
Alina Croitoru
Keyword(s):  
Quality Of Life ◽  
Muscle Weakness ◽  
Pulmonary Rehabilitation ◽  
Functional Independence ◽  
Daily Activities ◽  
New Approach ◽  
Antituberculous Treatment ◽  
Long Time ◽  
The Impact

Abstract Tuberculosis (TB) is still a leading cause of morbidity and mortality worldwide. The impact on patient’s life is significant, leading to physical, mental and social deconditioning, not only in active TB but also in post TB sequela. Although with specific antituberculous treatment sputum negativity can be achieved, TB extrapulmonary symptoms such as cachexia, muscle weakness and depression may persist for a long time. The pulmonary rehabilitation (PR) may be a useful tool in this patient’s therapy in active and also in sequela phase. The benefits of PR are: reducing symptomatology, improving the degree of functional independence and quality of life, and increasing the ability to perform daily activities. This article discusses the components of a PR programme in active TB and TB sequela, and the results obtained by studies so far.

scholarly journals Comparison of the Effect of Custom Insole With CAD-CAM and Conventional Insole on FAOS Questionnaire Subscales in Patients With Plantar Fasciitis

2020 ◽  
Vol 21 (2) ◽  
pp. 256-271
Author(s):  
Sara Shojaie ◽  
◽  
Mahmood Bahramizade ◽  
Monireh Ahamadi Bani ◽  
Mohsen Movahedi Yeganeh ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Plantar Fasciitis ◽  
Daily Activities ◽  
Foot And Ankle ◽  
Custom Made ◽  
Significant Difference ◽  
Cad Cam ◽  
Pain Symptoms ◽  
The Impact

Objective: One of the significant causes of foot pain is plantar fasciitis. The use of medical insoles is a conventional treatment for this condition. The purpose of this study was to compare the effect of the customized insole with the CAD-CAM and conventional insole on pain, symptoms, daily activity, exercise and recreational activity, and quality of life in patients with PF. Materials & Methods: This quasi-experimental study was performed on 14 patients with plantar fasciitis (five women and nine men) with the mean age of 40 years. Fourteen patients have been diagnosed with orthopedic pain after being diagnosed with plantar fasciitis according to inclusion criteria. Diagnosis of the complication of plantar fasciitis by orthopedic physician, Patients with flexible flat foot. No neurological disorders or any foot pathology such as diabetes and osteoarthritis. Patients were randomly assigned into two groups of 7 using customized insole with CAD-CAM and conventional (prefabricated) insole. From the outset it was found to be one of two types of insole to be studied: first the patient was given a CNC insole, and the other 13 patients received the same insole and divided into two groups. The instrument of this study was the FAOS questionnaire (foot and ankle outcomes) which measures the five variables of pain, symptoms, daily activities, sports and recreational activities, and quality of life. Both groups completed the questionnaire before using the insole and again after six weeks. Compressive scan of both groups was accomplished using EMED foot pressure system. The custom-made insole was designed using Rhino Cross software and then shaved using EVA foam blocks with 50% shore using a CNC machine. In the conventional insoles group, patients received conventional polyurethane insoles based on the length measurements of the single leg. Patients completed the questionnaire again after six weeks. Data were analyzed by SPSS software v. 22. After checking the normality of the data by Shapiro-Wilk test, non-parametric Mann-Whitney and Wilcoxon tests were used to analyze the data. Results: In the pre-intervention phase, there was no significant difference in pain, symptoms, daily activities, recreational-sports activities, and quality of life in the two groups, and the two groups were homogeneous. After six weeks, there was a significant difference between the two groups in the FAOS questionnaire (P<0.05). There was no significant difference between the two groups in pain score, symptoms, daily activities, recreational-sport activities, and quality of life (P <0.05). Conclusion: According to the results of this study, both customized insoles with CAD-CAM and conventional insoles are effective in improving FAOS questionnaire subscales. There was no significant difference in the impact between the two types of insoles in foot and ankle.

scholarly journals Impact of Alzheimer’s disease on the quality of life and daily activities of the elderly

2021 ◽  
Author(s):  
Daniele Sutherland W. Rizziolli ◽  
Ana Maria Ramos Miranda ◽  
Andressa Schimidt do Nascimento ◽  
Cristiane dos Santos Lima ◽  
Jade Menezes Maia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
The Elderly ◽  
Daily Activities ◽  
Strong Impact ◽  
Mesh Terms ◽  
Final Sample ◽  
The Impact

Introduction: With the increase in life expectancy, there is an increase in Alzheimer’s Disease (AD). Characterized by being a degenerative and irreversible neurological disease, that leads to developing a dependence for daily activities. Objective:To analyze the impact of AD on the quality of life and daily activities of the elderly. Methodology:Integrative literature review, with bibliographic survey carried out on an international basis (PUBMED). Criteria for the selection of articles was: be published in English, in the period 2018-2020, available in full, whose theme was “Impacts on the quality of life that AD causes in the elderly”. Results: For the sample of this review 59 articles were selected, of which 48 articles were not specific to the topic, leaving a final sample of 11 articles included in the review. Identifying that AD has a strong impact on patient’s quality of life, such as reduced autonomy and dependence on daily activities. Conclusion: It was observed that there is a reduction in the quality of life of patients with AD, related to loss of autonomy and dependence in daily activities. Mesh- Terms: Degenerative Disease, Aged, Insanity.

scholarly journals The Impact of Hyperhidrosis on Patients’ Quality of Life and Daily Activities

2021 ◽  
Vol 10 (2) ◽  
pp. 77-83
Author(s):  
Mohammad Almohideb ◽  
Mohammed Aljihani ◽  
Meshal Bukhari ◽  
Bashayer Algethami ◽  
Omar Asiri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Daily Activities ◽  
The Impact

scholarly journals Real-world study of the impact of recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) on quality of life and productivity in Europe

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Prianka Singh ◽  
Bryan Bennett ◽  
Tom Bailey ◽  
Gavin Taylor-Stokes ◽  
Ivana Rajkovic ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Real World ◽  
Work Productivity ◽  
Daily Activities ◽  
First Line ◽  
The Impact

Abstract Background Although current therapy for patients with early-stage squamous cell carcinoma of the head and neck (SCCHN) is potentially curative, the recurrence rate is high. Patients with recurrent or metastatic (R/M) SCCHN have a poor prognosis and substantial disease burden, including impaired health-related quality of life (HRQoL), productivity loss and indirect costs, such as need for caregiver support. The aim of this study was to characterize the impact of R/M SCCHN and its first-line treatment on patient and caregiver quality of life, daily activities and work productivity using real-world evidence from Europe. Methods This was a multicentre retrospective study of patients with R/M SCCHN in France, Germany, Italy, Spain and the United Kingdom incorporating patient and caregiver surveys, and a physician-reported medical chart review, conducted between January and May 2019. Patients aged 18 or over with a physician confirmed diagnosis R/M SCCHN completed four validated measures of disease activity and its impact on quality of life and work productivity, while caregivers also completed questionnaire to assess the burden of providing care. Physicians provided data for clinical characteristics, patient management, testing history and treatment patterns. Results A total of 195 medical/clinical oncologists provided data for 937, predominantly male (72%) patients, with almost half of patients aged over 65 years. The most frequently reported symptoms were fatigue (43%), weight loss (40%), pain (35%) and difficulty swallowing (32%). The EXTREME regimen was the most common first line therapy in over half of patients, who reported moderate or extreme pain/discomfort, and anxiety/depression, and problems with self-care resulting in a diminished health status compared with the general population. Only 14% were employed with high absenteeism or presenteeism, and over half of patients had a caregiver for whom the burden of care was substantial. Conclusion Our results provide real-world insight into the multi-faceted burden associated with R/M SCCHN. The combination of poor HRQoL and the impairment in daily activities, social life and employment illustrates the wider impact of R/M SCCHN on patients and their caregivers, and highlights a need for novel 1 L treatment regimens to improve the humanistic and productivity burdens of this cancer.

scholarly journals Panic agoraphobic spectrum in psychiatrically healthy subjects: Impact on quality of life

2009 ◽  
Vol 18 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Arianna Goracci ◽  
Andrea Fagiolini ◽  
Carmela Salviulo ◽  
Rocco Nicola Forgione ◽  
Mirko Martinucci ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Distress ◽  
Anxiety Disorders ◽  
Psychosocial Functioning ◽  
Panic Attacks ◽  
Daily Activities ◽  
Dsm Iv ◽  
The Impact ◽  
The Relationship

Several studies have evaluated the quality of life (QOL) in patients with Panic Disorder (PD). For instance, the Epidemiological Catchment Area Study (ECA) assessed the quality of life (QoL) using the subjective evaluation of health, psychosocial functioning and financial status as parameters (Regier et al., 1984). Among the general population, people with PD or panic attacks reported a low level of physical health in 35% of cases and a low degree of mental health in 38% of cases, similarly to people suffering from Major Depressive Disorder (29% and 39% respectively), but more frequently than the in individuals not affected by any disorder (24% and 12% respectively). Furthermore, 27% of patients with PD were in need of some form of social or financial support in contrast to 16% of people suffering from depression and 12% of unaffected people. The National Comorbidity Survey (NCS) (Magee et al., 1996) found serious interference in activities in 27% of agoraphobic patients. For instance, the agoraphobic subjects reported an average of 1.1 days of work lost in the previous month due to their psychopathology. Several Authors have studied the relationship between PD and a worse quality of life and/or a worse ability to function. In a review on the topic, Mendlowicz & Stein (2000) provided an integrated view of the issue of quality of life in patients with anxiety disorders and concluded that the existing studies almost uniformly show a marked impairment of quality-of-life and psychosocial functioning in individuals with anxiety disorders. However, as noted by the Authors above, “despite the growing number of studies undertaken during the past 15 years, the investigation of quality of life in individuals with anxiety disorders is still in its infancy.” Rucci et al. (1993) evaluated the prevalence of subthreshold psychiatric disorders in primary care and their association with the patients health perception, disability in daily activities and psychological distress Subjects with subthreshold disorders reported levels of psychological distress, disability in daily activities and perceived health comparable to those of patients with full-fledged ICD-10 disorders. Despite the scientific and clinical importance of the topic, relatively few studies have evaluated the prevalence and impact of subthreshold affective disorders in general (Schotte & Cooper, 1999) and panic symptoms in particular (for instance Bellini & Galverni, 2003) in non psychiatric populations. Moreover, the literature on the relationship between sub-threshold or residual PD and quality of life is scant. To this end, we decided to investigate the impact of panic-agoraphobic “spectrum” on the quality of life of subjects who did not meet the criteria for a full blown PD. We adopted the definition of “spectrum” developed by Cassano and colleagues (Cassano & Pini, 2000; Rucci & Maser, 2000), which refers to a dimensional view of psychopathology that includes a broad array of manifestations of the target disorder, including its most severe symptoms as well as a range of more subtle features related to the core condition, which may include temperamental traits, prodromal indicators, or residual symptoms. Although they are frequently associated with specific DSM-IV disorders, these conditions are also found in individuals who have never met full DSM-IV diagnostic criteria. Our hypothesis for this study was that the presence of subthreshold panic-agoraphobic symptomatologies in otherwise healthy individuals would significantly impair the quality of life despite the absence of a full-blown PD diagnosis.

scholarly journals The Prevalence, Management and Impact of Dysmenorrhea on Medical Students’ Lives—A Multicenter Study

Healthcare ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 157
Author(s):  
Romina-Marina Sima ◽  
Mihaela Sulea ◽  
Julia Caroline Radosa ◽  
Sebastian Findeklee ◽  
Bashar Haj Hamoud ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Medical Students ◽  
Social Life ◽  
Female Students ◽  
Menstrual Period ◽  
Daily Activities ◽  
University Courses ◽  
The Impact ◽  
As If

Introduction: Dysmenorrhea is defined as the presence of painful menstruation, and it affects daily activities in different ways. The aims of this study were to assess the prevalence and management of dysmenorrhea and to determine the impact of dysmenorrhea on the quality of life of medical students. Material and methods: The study conducted was prospective, analytical and observational and was performed between 7 November 2019 and 30 January 2020 in five university centers from Romania. The data was collected using an original questionnaire regarding menstrual cycles and dysmenorrhea. The information about relationships with family or friends, couples’ relationships and university activity helped to assess the effects of dysmenorrhea on quality of life. The level of significance was set at p < 0.05. Results: The study comprised 1720 students in total. The prevalence of dysmenorrhea was 78.4%. During their menstrual period, most female students felt more agitated or nervous (72.7%), more tired (66.9%), as if they had less energy for daily activities (75.9%) and highly stressed (57.9%), with a normal diet being difficult to achieve (30.0%). University courses (49.4%), social life (34.5%), couples’ relationships (29.6%), as well as relationships with family (21.4%) and friends (15.4%) were also affected, depending on the duration and intensity of the pain. Conclusion: Dysmenorrhea has a high prevalence among medical students and could affect the quality of life of students in several ways. During their menstrual period, most female students feel as if they have less energy for daily activities and exhibit a higher level of stress. The intensity of the symptoms varies considerably and, with it, the degree of discomfort it creates. Most student use both pharmacological and non-pharmacological methods to reduce pain (75.7%). University courses, social life, couples’ relationships, as well as relationships with family and friends are affected, depending on the duration and intensity of the pain.

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