Polysaccharides in the different stages of the life-cycles of certain sporozoa

Parasitology ◽  
1960 ◽  
Vol 50 (3-4) ◽  
pp. 509-514 ◽  
Author(s):  
B. Dasgupta
Keyword(s):  
Positive Reaction ◽  
Life Cycles ◽  
Negative Reaction ◽  
Malaria Parasites ◽  
Residual Mass ◽  
Strong Positive Reaction ◽  
Residual Masses

Glycogen proved to be absent in the malaria parasites (Plasmodium and Hepatocystis) by applying cytochemical methods; while in the piroplasms (Theileria and Babesia), and in Hepatozoon glycogen could be demonstrated by using the same methods. A strong positive reaction for polysaccharides was obtained in the residual masses of Hepatozoon sciuri, and H. balfouri; while a negative reaction was obtained in the residual mass of Plasmodium. A positive reaction for polysaccharides was obtained in the following structures: the wall of the oocysts of Plasmodium, the gametocyte capsules of Hepatozoon sciuri and Hepatozoon sp., the sporoblast capsule of H. sciuri, and the polar areas of the gametocyte of H. balfouri.

scholarly journals Political Quotas in India

Asian Survey ◽  
2012 ◽  
Vol 52 (2) ◽  
pp. 373-394 ◽  
Author(s):  
Francesca Refsum Jensenius
Keyword(s):  
Positive Reaction ◽  
National Election ◽  
Negative Reaction ◽  
Election Study ◽  
National Election Study ◽  
Strong Positive Reaction ◽  
Scheduled Castes

Abstract India has had political quotas for Scheduled Castes (SCs) since 1950. Using the 2004 National Election Study, this paper finds that neither SCs nor non-SCs feel that their vote is more/less efficacious living in SC constituencies. Yet, some evidence is found in this study that SCs are approached for their vote more often in SC constituencies. Overall, this suggests that quotas are neither associated with a strong positive reaction among SC voters nor a strong negative reaction among non-SC voters.

Histochemical studies of dopa oxidase and peroxidase in the mantle-edge of the freshwater gastropod, Helisoma duryi eudiscus (Pilsbry)

1968 ◽  
Vol 46 (2) ◽  
pp. 165-167 ◽  
Author(s):  
S. P. Kapur ◽  
M. A. Gibson
Keyword(s):  
Positive Reaction ◽  
Protein Component ◽  
Negative Reaction ◽  
Structural Proteins ◽  
Freshwater Gastropod ◽  
Helisoma Duryi ◽  
Mantle Edge ◽  
Dopa Oxidase ◽  
Oxidase Reaction

The mantle-edge gland produces the highly tanned, densely fibrous periostracum, and the cubocolumnar cells contribute to the deposition of the less highly tanned matrix of the inner shell layers. The mantle-edge gland gives positive reactions for dopa oxidase and peroxidase, but does not contain melanin. The cubocolumnar cells reveal a positive reaction for dopa oxidase, possess numerous melanin granules, and exhibit a negative reaction for peroxidase. It is suggested that quinones may contribute to the process of tanning and hardening of the structural proteins of the shell. The dopa oxidase reaction within the cubocolumnar cells indicates the presence of tyrosine and suggests that these cells are capable of producing quinones to color and harden the protein component of the inner shell layers. It also explains the abundance of melanin granules within these cells. Within the mantle-edge gland, it is suggested that the peroxidase inhibits the formation of melanin from dopa quinone, and peroxidase, by accentuating quinone production, may cause further hardening of the periostracum.

The New Edition of the Guide to Clinical Preventive Services

PEDIATRICS ◽  
1996 ◽  
Vol 97 (5) ◽  
pp. 733-735
Author(s):  
Modena Wilson ◽  
Donald M. Berwick ◽  
Carolyn DiGuiseppi
Keyword(s):  
Primary Care ◽  
Positive Reaction ◽  
Task Force ◽  
Preventive Services ◽  
Negative Reaction ◽  
The Past ◽  
The Us ◽  
Clinical Preventive Services ◽  
Clinical Prevention ◽  
And Training

Preventive services compose a large portion of primary care pediatrics, and pediatricians by their nature and training seem extraordinarily disposed toward clinical prevention. Therefore, when the first edition of the Guide to Clinical Preventive Services appeared in 1989 from the US Preventive Services Task Force (USPSTF), the negative reaction of the organized pediatric community was disappointing. The second edition of that guide has just been released, and we three pediatricians, who have worked hard during the past 5 years as members and staff of the second task force, hope for a far more positive reaction from our colleagues this time around.

Residual mass: an indication for further therapy in patients with advanced seminoma following systemic chemotherapy.

1987 ◽  
Vol 5 (7) ◽  
pp. 1064-1070 ◽  
Author(s):  
R Motzer ◽  
G Bosl ◽  
R Heelan ◽  
W Fair ◽  
W Whitmore ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Surgical Excision ◽  
Residual Tumor ◽  
Imaging Studies ◽  
Residual Mass ◽  
Viable Tumor ◽  
Close Observation ◽  
Residual Masses ◽  
Additional Therapy ◽  
Residual Viable Tumor

Forty-one advanced seminoma patients with normal biochemical markers and a complete or partial radiographic response after cisplatin-based chemotherapy had a complete reevaluation of all known sites of disease. Twenty-three patients had a residual mass, and in 14 the mass was greater than or equal to 3 cm. Nineteen patients with a residual mass, including 13 with a mass greater than or equal to 3 cm in diameter, had surgical excision or biopsy. Four patients had viable seminoma and one patient had teratoma; all five of these patients had residual masses greater than or equal to 3 cm. Four patients with a residual mass were observed without surgery. One patient with a residual mass greater than or equal to 3 cm progressed with biopsy-proven seminoma. Therefore, six of 14 patients (42%) with a residual mass greater than or equal to 3 cm had viable residual tumor. Eighteen patients had no residual mass after chemotherapy. Ten of these patients had surgery or biopsy; none had viable tumor, but two have relapsed. Eight patients were observed and none have relapsed. Advanced seminoma patients with a residual mass greater than or equal to 3 cm after chemotherapy are at high risk for residual viable tumor. Additional therapy is indicated for these patients. For patients with normal imaging studies or a residual mass less than 3 cm, close observation without surgery is generally possible.

Fibrosis in Nodular Sclerosis Hodgkin Lymphoma Is Predictive of a Residual Mass Following Therapy.

Blood ◽  
2009 ◽  
Vol 114 (22) ◽  
pp. 4630-4630
Author(s):  
Alanna J Church ◽  
Nasim Shabazi ◽  
David LeBrun ◽  
Tara Baetz
Keyword(s):  
Hodgkin Lymphoma ◽  
Functional Imaging ◽  
Conflicts Of Interest ◽  
Post Treatment ◽  
Line Treatment ◽  
Residual Mass ◽  
Nodular Sclerosis ◽  
Residual Masses ◽  
Initial Biopsy

Abstract Abstract 4630 Persistence of a mass after first-line treatment is a common problem in nodular sclerosis Hodgkin lymphoma (NSHL). Up to 64% of patients demonstrate residual abnormalities on computed tomography (CT) after therapy, but only 42% of those patients will relapse on follow-up. This is primarily caused by the inability of CT to distinguish viable tumor tissue from fibrosis. Clinicians are faced with the dilemma of whether to pursue second-line treatment for a mass that may be simply scar tissue. The ability to predict which patients are at higher risk for residual mass following curative treatment can aid in the planning of follow-up imaging modalities such as positron emission tomography (PET) scanning which can map out metabolically active tissue (i.e. tumor versus fibrosis) and the need for biopsy of a residual mass. This study was designed to test the hypothesis that the presence of abundant fibrosis in the initial biopsy predicts the presence of residual, post-therapy masses composed primarily of fibrotic tissue. Subjects were consecutive NSHL patients from the years 1996 to 2007 identified from our institution based on the availability of histology slides from the initial diagnostic biopsy, clinical follow-up data, and the results of post-treatment imaging investigations. The initial biopsies were reviewed by a lymphoma pathologist and resident without knowledge of the residual mass status. The proportion of the tissue consisting of fibrous material was graded as a percentage of the total biopsy tissue. The clinical charts were reviewed for baseline patient characteristics, cancer stage and the presence of a residual mass on CT scan 6 months after treatment. Of the 47 subjects included in the study, 25 had residual masses and 22 had none. Patients with increased fibrosis on initial biopsy were significantly more likely to have a residual mass after initial therapy (p=0.028). The degree of fibrosis was independent of gender, stage, and Hasenclever score. Degree of fibrosis was the only factor that was predictive of the presence of a residual mass. Of the 16 patients with residual masses with follow-up Gallium imaging, the result of the scan was more likely to be negative (indicating that the mass is not metabolically active) for patients with a high grade of initial fibrosis (p=0.148). Taken together, these results suggest that patients with increased fibrosis on their initial NSHL biopsy are more likely to have residual masses, but that these masses are less likely to be malignant. The results support the hypothesis that the degree of fibrosis at the initial NSHL biopsy is predictive of a post-treatment residual mass. These findings have potential implications for patient follow-up: clinicians whose patients have abundant fibrosis at initial biopsy may be reassured that a post-treatment residual mass is less likely to represent persistent malignancy and thus can be followed with functional imaging rather than pursuing unnecessary biopsies. Our results further reinforce the importance of functional imaging like PET, particularly in this patient population Disclosures: No relevant conflicts of interest to declare.

A case of hepatic carcinoid in a red deer hind (Cervus elaphus)

2011 ◽  
Vol 59 (3) ◽  
pp. 319-325 ◽  
Author(s):  
Diana Žele ◽  
Mitja Gombač ◽  
Tanja Švara ◽  
Gorazd Vengušt
Keyword(s):  
Positive Reaction ◽  
Cervus Elaphus ◽  
Chromogranin A ◽  
Red Deer ◽  
Carcinoid Tumour ◽  
Neuron Specific Enolase ◽  
Neoplastic Cells ◽  
First Report ◽  
Strong Positive Reaction ◽  
Hepatic Carcinoid

A carcinoid tumour in the liver of a red deer hind (Cervus elaphus) is described. Macroscopically, the liver was considerably enlarged with multifocal, firm, yellow and red nodular neoplastic masses, which were histopathologically diagnosed as hepatic carcinoids. The diagnosis was confirmed by modified Grimelius staining, which demonstrated numerous small argyrophilic granules in the cytoplasm of neoplastic cells, and by immunohistochemistry. The neoplastic cells gave a strong positive reaction for neuron-specific enolase (NSE) and synaptophysin and a weak positive reaction for chromogranin A. To our knowledge, this is the first report of a hepatic carcinoid in red deer.

Residual abdominal masses in aggressive non-Hodgkin's lymphoma after combination chemotherapy: significance and management.

1988 ◽  
Vol 6 (12) ◽  
pp. 1832-1837 ◽  
Author(s):  
A Surbone ◽  
D L Longo ◽  
V T DeVita ◽  
D C Ihde ◽  
P L Duffey ◽  
...  
Keyword(s):  
Complete Remission ◽  
Combination Chemotherapy ◽  
Residual Disease ◽  
Aggressive Lymphoma ◽  
Radiographic Examination ◽  
Bulky Disease ◽  
Residual Mass ◽  
Negative Laparotomy ◽  
Abdominal Masses ◽  
Residual Masses

When patients with aggressive lymphoma present with intraabdominal disease, a stable residual mass is frequently detected radiographically at the time of the clinical complete remission. To discern the optimal management for this clinical problem, we reviewed 241 patients with aggressive lymphoma treated at the National Cancer Institute (NCI) from 1977 to 1986. Seventy-two/241 patients (30%) had an abdominal mass at diagnosis and 29/72 (40%) were left with a radiographically detectable residual mass at clinical complete remission. The likelihood of a residual mass was much higher for patients with bulky disease (P2 less than .0003) (two-tailed test [P2]). Twenty-nine patients had radiologically stable residual masses after therapy, and of 22 (76%) with pathologic evaluations, 21 had negative specimens (95%) and one was positive (5%). None of the patients with negative pathologic evaluation has relapsed in the abdominal site (median follow-up, 31 months). Seven patients were observed clinically without laparotomy: five are alive, without evidence of disease, at 2 to 9 years; two relapsed with disseminated disease within 2 months of chemotherapy. Initial tumor size and size of the residual mass did not correlate with residual disease, since residual masses identified by radiographic examination did not usually harbor viable lymphoma cells. Aspiration cytology was negative for residual tumor in 15/16 cases. One negative result was not confirmed at laparotomy, presumably due to sampling error. The one positive aspiration was followed by a negative laparotomy, possibly due to subsequent tumor necrosis. Restaging laparotomy has a low yield. In most patients with aggressive lymphoma who have otherwise completely responded to carefully administered full-dose combination chemotherapy, stable residual abdominal masses can be closely followed clinically without surgical exploration.

scholarly journals Isolation of natural inhibitors of papain obtained from Carica papaya latex

2004 ◽  
Vol 47 (5) ◽  
pp. 747-754 ◽  
Author(s):  
Rubens Monti ◽  
Jonas Contiero ◽  
Antonio José Goulart
Keyword(s):  
Positive Reaction ◽  
Carica Papaya ◽  
Competitive Inhibition ◽  
Gel Filtration ◽  
Exchange Chromatography ◽  
Negative Reaction ◽  
Ionic Exchange ◽  
Papaya Latex ◽  
Carica Papaya Latex ◽  
Natural Inhibitors

Studies were carried out to natural papain inhibitor from papaya latex. Fresh latex from green fruits of Carica papaya was collected and immediately transported in ice bath to the lab, from which three fractions with inhibitor effect of esterase papain activity were isolated by latex dialysis, Sephadex G-25 gel filtration and ionic exchange chromatography in SP-Sephadex C-25. The isolated fractions, identified as inhibitors I and II, showed a negative reaction with ninhydrin; however, the fraction identified as P-III showed positive reaction with ninhydrin. Kinetics data showed non-competitive inhibition (inhibitor I) and uncompetitive (inhibitors II and P-III).

scholarly journals To the treatment and cure of gonorrhea

2021 ◽  
Vol 25 (11) ◽  
pp. 1238-1238
Author(s):  
A. Dmitriev
Keyword(s):  
Mucous Membrane ◽  
Positive Reaction ◽  
Microscopic Examination ◽  
Negative Reaction ◽  
Years Of Experience ◽  
Protein Therapy ◽  
Hot Baths

Schollz (D. m. W. No. 31, 29), on the basis of his many years of experience in the treatment of gonorrhea, indicates that Protargol and Albargin remain the best drugs to this day, because they act not only in a killing manner on gonococci, but also exert their influence on mucous membrane in the sense of its impregnation. In cases where gonococci sit deep in tissues (prostata, epididymis, ovaries), the author recommends using protein therapy. In stubborn cases, it is recommended to "Fieberbehandlung" with hot baths or inoculation with malaria. To establish the fact that gonorrhea has been cured, the author uses microscopic examination after a series of provocations, and also examines the patient with the help of cultures. An excellent means for establishing the cure of gonorrhea is the B.-G. reaction, and a negative reaction that occurred after the previous positive one is more likely to speak for a cure, while a persistent positive reaction indicates the need for a series of repeated microscopic and bacteriological studies.

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