Evidence for a domain-specific deficit in developmental dyslexia

2002 ◽  
Vol 25 (6) ◽  
pp. 767-768 ◽  
Author(s):  
Franck Ramus
Keyword(s):  
Cognitive Deficits ◽  
Developmental Dyslexia ◽  
Developmental Disorders ◽  
Cognitive Deficit ◽  
A Priori ◽  
Domain Specific ◽  
The Core

Thomas & Karmiloff-Smith (T&K-S) claim that “Residual Normality” is a priori unlikely, that is, that specific cognitive deficits should not exist in developmental disorders. Here I review evidence that a specific cognitive deficit is at the core of developmental dyslexia and I provide a possible neurological account thereof.

The Logicism of Frege, Dedekind, and Russell

2009 ◽  
Author(s):  
William Demopoulos ◽  
Peter Clark
Keyword(s):  
A Priori ◽  
The Core ◽  
Common Thread ◽  
Synthetic A Priori ◽  
The Common

This article is organized around logicism's answers to the following questions: What is the basis for our knowledge of the infinity of the numbers? How is arithmetic applicable to reality? Why is reasoning by induction justified? Although there are, as is seen in this article, important differences, the common thread that runs through all three of the authors discussed in this article their opposition to the Kantian thesis that reflection on reasoning with mere concepts (i.e., without attention to intuitions formed a priori) can never succeed in providing satisfactory answers to these three questions. This description of the core of the view differs from more usual formulations which represent the opposition to Kant as an opposition to the contention that mathematics in general, and arithmetic in particular, are synthetic a priori rather than analytic.

scholarly journals Is the Letter ‘t’ in the Word ‘gourmet’? Disruption in Task-Evoked Connectivity Networks in Adults with Impaired Literacy Skills

NeuroSci ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 75-94
Author(s):  
Kulpreet Cheema ◽  
William E. Hodgetts ◽  
Jacqueline Cummine
Keyword(s):  
Developmental Disorders ◽  
Brain Networks ◽  
Literacy Skills ◽  
Resting State Networks ◽  
Skilled Readers ◽  
University Of Alberta ◽  
Domain Specific ◽  
Probe Task ◽  
The University ◽  
General Networks

Much work has been done to characterize domain-specific brain networks associated with reading, but very little work has been done with respect to spelling. Our aim was to characterize domain-specific spelling networks (SpNs) and domain-general resting state networks (RSNs) in adults with and without literacy impairments. Skilled and impaired adults were recruited from the University of Alberta. Participants completed three conditions of an in-scanner spelling task called a letter probe task (LPT). We found highly connected SpNs for both groups of individuals, albeit comparatively more connections for skilled (50) vs. impaired (43) readers. Notably, the SpNs did not correlate with spelling behaviour for either group. We also found relationships between SpNs and RSNs for both groups of individuals, this time with comparatively fewer connections for skilled (36) vs. impaired (53) readers. Finally, the RSNs did predict spelling performance in a limited manner for the skilled readers. These results advance our understanding of brain networks associated with spelling and add to the growing body of literature that describes the important and intricate connections between domain-specific networks and domain-general networks (i.e., resting states) in individuals with and without developmental disorders.

scholarly journals Intra-Storm Pattern Recognition through Fuzzy Clustering

Hydrology ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 57
Author(s):  
Konstantinos Vantas ◽  
Epaminondas Sidiropoulos
Keyword(s):  
Fuzzy Clustering ◽  
A Priori ◽  
Temporal Distribution ◽  
Distribution Patterns ◽  
Rainfall Data ◽  
Rainfall Runoff ◽  
Domain Specific ◽  
Runoff Modeling ◽  
National Bank ◽  
Rainfall Patterns

The identification and recognition of temporal rainfall patterns is important and useful not only for climatological studies, but mainly for supporting rainfall–runoff modeling and water resources management. Clustering techniques applied to rainfall data provide meaningful ways for producing concise and inclusive pattern classifications. In this paper, a timeseries of rainfall data coming from the Greek National Bank of Hydrological and Meteorological Information are delineated to independent rainstorms and subjected to cluster analysis, in order to identify and extract representative patterns. The computational process is a custom-developed, domain-specific algorithm that produces temporal rainfall patterns using common characteristics from the data via fuzzy clustering in which (a) every storm may belong to more than one cluster, allowing for some equivocation in the data, (b) the number of the clusters is not assumed known a priori but is determined solely from the data and, finally, (c) intra-storm and seasonal temporal distribution patterns are produced. Traditional classification methods include prior empirical knowledge, while the proposed method is fully unsupervised, not presupposing any external elements and giving results superior to the former.

scholarly journals A clarified typology of core-periphery structure in networks

2021 ◽  
Vol 7 (12) ◽  
pp. eabc9800
Author(s):  
Ryan J. Gallagher ◽  
Jean-Gabriel Young ◽  
Brooke Foucault Welles
Keyword(s):  
Dense Core ◽  
Block Model ◽  
Hub And Spoke ◽  
Block Modeling ◽  
Domain Specific ◽  
The Core ◽  
Detailed Case ◽  
Rich Diversity ◽  
Modeling Techniques

Core-periphery structure, the arrangement of a network into a dense core and sparse periphery, is a versatile descriptor of various social, biological, and technological networks. In practice, different core-periphery algorithms are often applied interchangeably despite the fact that they can yield inconsistent descriptions of core-periphery structure. For example, two of the most widely used algorithms, the k-cores decomposition and the classic two-block model of Borgatti and Everett, extract fundamentally different structures: The latter partitions a network into a binary hub-and-spoke layout, while the former divides it into a layered hierarchy. We introduce a core-periphery typology to clarify these differences, along with Bayesian stochastic block modeling techniques to classify networks in accordance with this typology. Empirically, we find a rich diversity of core-periphery structure among networks. Through a detailed case study, we demonstrate the importance of acknowledging this diversity and situating networks within the core-periphery typology when conducting domain-specific analyses.

Evaluation of acetylcholinesterase activity and behavioural alterations induced by ketamine in an animal model of schizophrenia

2013 ◽  
Vol 26 (1) ◽  
pp. 43-50 ◽  
Author(s):  
Alexandra I. Zugno ◽  
Maria Paula Matos ◽  
Leila Canever ◽  
Daiane B. Fraga ◽  
Renata D. De Luca ◽  
...  
Keyword(s):  
Animal Model ◽  
Cognitive Deficits ◽  
Cholinergic System ◽  
Ache Activity ◽  
Cognitive Deficit ◽  
Chronic Administration ◽  
Inhibitory Avoidance ◽  
Acetylcholinesterase Activity ◽  
Chronic Effects ◽  
Behavioural Tests

ObjectiveCognitive deficits in schizophrenia play a crucial role in its clinical manifestation and seem to be related to changes in the cholinergic system, specifically the action of acetylcholinesterase (AChE). Considering this context, the aim of this study was to evaluate the chronic effects of ketamine in the activity of AChE, as well as in behavioural parameters involving learning and memory.MethodsThe ketamine was administered for 7 days. A duration of 24 h after the last injection, the animals were submitted to behavioural tests. The activity of AChE in prefrontal cortex, hippocampus and striatum was measured at different times after the last injection (1, 3, 6 and 24 h).ResultsThe results indicate that ketamine did not affect locomotor activity and stereotypical movements. However, a cognitive deficit was observed in these animals by examining their behaviour in inhibitory avoidance. In addition, an increase in AChE activity was observed in all structures analysed 1, 3 and 6 h after the last injection. Differently, serum activity of AChE was similar between groups.ConclusionChronic administration of ketamine in an animal model of schizophrenia generates increased AChE levels in different brain tissues of rats that lead to cognitive deficits. Therefore, further studies are needed to elucidate the complex mechanisms associated with schizophrenia.

scholarly journals Seeing through brain fog: disentangling the cognitive, physical, and mental health sequalae of COVID-19.

2021 ◽  
Author(s):  
Conor Wild ◽  
Loretta Norton ◽  
David Menon ◽  
David Ripsman ◽  
Richard Swartz ◽  
...  
Keyword(s):  
Mental Health ◽  
Cognitive Deficits ◽  
Subjective Experience ◽  
Short Term Memory ◽  
Physical Symptoms ◽  
Physical And Mental Health ◽  
Cognitive Measures ◽  
Online Study ◽  
Domain Specific ◽  
Overall Performance

Abstract As COVID-19 cases exceed hundreds of millions globally, it is clear that many survivors face cognitive challenges and prolonged symptoms. However, important questions about the cognitive impacts of COVID-19 remain unresolved. In the present online study, 485 volunteers who reported having had a confirmed COVID-positive test completed a comprehensive cognitive battery and an extensive questionnaire. This group performed significantly worse than pre-pandemic controls on cognitive measures of reasoning, verbal, and overall performance, and processing speed, but not short-term memory – suggesting domain-specific deficits. We identified two distinct factors underlying health measures: one varying with physical symptoms and illness severity, and one with mental health. Crucially, cognitive deficits were correlated with physical symptoms, but not mental health, and were evident even in cases that did not require hospitalisation. These findings suggest that the subjective experience of “long COVID” or “brain fog” relates to a combination of physical symptoms and cognitive deficits.

scholarly journals To Be Or Not To Be? What Makes a Child Dyslexic: An Overview on Risk Factors and Correlated Clinical Aspects

2020 ◽  
pp. 1-11
Author(s):  
Claudio Rosa ◽  
Carlo Aleci
Keyword(s):  
Risk Factors ◽  
Early Diagnosis ◽  
Reading Disability ◽  
Developmental Dyslexia ◽  
Environmental Variables ◽  
Developmental Disorders ◽  
Genetic Basis ◽  
Environmental Influence ◽  
Phenotypic Expression ◽  
Clinical Aspects

Developmental dyslexia, one of the most common neuro-developmental disorders, is frequently under-diagnosed or diagnosed late. Despite there is consensus on the neurobiological and genetic basis and on the environmental influence, the multi-faceted aspects of dyslexia and the complexity of its phenotypic expression hinder the identification of the risk factors. Indeed, determining risk factors and understanding how they predispose to the reading disability is important for an early diagnosis and a satisfactory rehabilitative outcome. The aim of this paper is therefore to provide an overview on the genetic, biochemical, anatomical and environmental variables involved in the pathogenesis of developmental dyslexia, and on the visual-perceptual aspects that characterize children who struggle to read.

Analogism at Chavín de Huántar

2019 ◽  
pp. 79-98
Author(s):  
Nicco La Mattina
Keyword(s):  
A Priori ◽  
Theoretical Framework ◽  
Core Beliefs ◽  
Archaeological Record ◽  
The Core ◽  
Chavin De Huantar ◽  
Chavín De Huántar ◽  
A Site ◽  
Material Record

Approaches to understanding the core beliefs and worldviews of ancient peoples are not superficially facilitated by the archaeological record. Sometimes, pre-Columbian people are described by analogy to presumably similar contemporary people; that is, a theoretical framework applicable to certain modern peoples is applied a priori in the investigation of a site. This chapter argues that at Chavín de Huántar, interpretations centred around animism and shamanism employ these concepts a priori as ways of understanding the material record. Many of the references to shamanism make specific analogies to Amazonian practices and import these ideas to Chavín de Huántar. Furthermore, the chapter authors argue that, if the iconographic and material record at Chavín de Huánta are carefully evaluated, interpretations centred around animism and shamanism will not follow. The authors demonstrate that the analogist ontology formulated by Descola finds a firmer grounding in the iconographic and material record when these are considered together.

Philosophy of Economics

2018 ◽  
Author(s):  
Mikaël Cozic
Keyword(s):  
Behavioral Economics ◽  
Mathematical Models ◽  
A Priori ◽  
The Core ◽  
Philosophy Of Economics ◽  
Empirical Significance ◽  
Bona Fide ◽  
The Impact ◽  
Empirical Methodology ◽  
Recent Extension

Although there are no doubts regarding the impact of economics in society and politics, doubts regarding its epistemological status endure. Does economics provide us with bona fide empirical theories? Are its mathematical models on a par with those of the hard sciences, or is its scientific character exaggerated? This chapter focuses on the key problem of the philosophy of economics: the reconciliation of its claim to empirical significance with what often appears as a non-empirical methodology, favoring deduction from a priori principles and showing little sensitivity to refutation by observation and experiment. Several attempts at answering this problem are considered, both in the Millian tradition and following neo-positivist approaches. Finally, the empirical status of the discipline is put in perspective with its recent extension to new fields of inquiry, such as behavioral economics and neuroeconomics, where experiments seem to be part of the core methodology.

Activating, seeking, and creating common ground

2009 ◽  
Vol 17 (2) ◽  
pp. 331-355 ◽  
Author(s):  
Istvan Kecskes ◽  
Fenghui Zhang
Keyword(s):  
Mental Representation ◽  
Common Ground ◽  
A Priori ◽  
Emergent Property ◽  
Shared Knowledge ◽  
Construction Process ◽  
Cognitive Approach ◽  
The Core ◽  
Communicative Process ◽  
Integrated Concept

This paper argues that current pragmatic theories fail to describe common ground in its complexity because they usually retain a communication-as-transfer-between-minds view of language, and disregard the fact that disagreement and egocentrism of speaker-hearers are as fundamental parts of communication as agreement and cooperation. On the other hand, current cognitive research has overestimated the egocentric behavior of the dyads and argued for the dynamic emergent property of common ground while devaluing the overall significance of cooperation in the process of verbal communication. The paper attempts to eliminate this conflict and proposes to combine the two views into an integrated concept of common ground, in which both core common ground (assumed shared knowledge, a priori mental representation) and emergent common ground (emergent participant resource, a post facto emergence through use) converge to construct a dialectical socio-cultural background for communication.
Both cognitive and pragmatic considerations are central to this issue. While attention (through salience, which is the cause for interlocutors’ egocentrism) explains why emergent property unfolds, intention (through relevance, which is expressed in cooperation) explains why presumed shared knowledge is needed. Based on this, common ground is perceived as an effort to converge the mental representation of shared knowledge present as memory that we can activate, shared knowledge that we can seek, and rapport, as well as knowledge that we can create in the communicative process. The socio-cognitive approach emphasizes that common ground is a dynamic construct that is mutually constructed by interlocutors throughout the communicative process. The core and emergent components join in the construction of common ground in all stages, although they may contribute to the construction process in different ways, to different extents, and in different phases of the communicative process.

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