empirical significance
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2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Francesco Caputo ◽  
Fabio Fiano ◽  
Massimiliano Farina Briamonte ◽  
Marco Sorrentino

Purpose Operating in a variety of countries, multinational companies (MNCs) experience a high variety and variability of physiological and contextual dynamics, requiring a more careful knowledge management approach. In this scenario, this paper aims to investigate the entrepreneurial facets and managerial aspects (entrepreneurial orientation/managerial intentionality) of MNCs’ internationalization from a knowledge-based perspective. Design/methodology/approach A theory-building approach is applied, involving a comparative case study of two MNCs conceived through the separation of a unique family business. Aiming to enrich the research about companies’ internationalization, some crucial elements are individuated to build a theoretical frame explaining the evolutionary paths of so-called born global. Findings This paper shows that companies’ internationalization development is based on a multiplicity of variables and underlines the need to incorporate different points of view when attempting to explain the dynamics of internationalization processes. Research limitations/implications The empirical significance of the two cases does not legitimize theorization. However, this research presents interesting results that could be strengthened by a series of comparative case studies dealing with other MNCs or deeper quantitative investigation. Originality/value This research approach could be considered as stimulating by the scientific and managerial community, as the internationalization process is articulated by mixing managerial, entrepreneurial and cognitive aspects.


Author(s):  
Paula Sarita Bigio Schnaider ◽  
Maria Sylvia Macchione Saes ◽  
Emmanuel Raynaud

In this paper, we rely on an extended version of the traditional transaction cost economics (TCE) framework to explain the variety of plural forms in the governance of food supply chains. Relying on the interplay of two transactional attributes – asset specificity and uncertainty – we explore not only the existence of plural forms, but their empirical diversity. This aspect has been largely under-explored and very little has been done empirically so far in this respect, despite its empirical significance. From an organizational point of view, this diversity requires an explanation as they carry different governance properties. We propose that while both are important drivers for the prevalence of plural forms, each of them plays a different role in their composition. Whereas uncertainty determines the type of plural form, asset specificity determines the level of coordination within the plural form and sheds light in the relative weights of each organizational arrangement composing it. An embedded case study of the Korin firm in Brazil, a leading firm in the organic food market, illustrates.


2021 ◽  
Vol 13 (23) ◽  
pp. 13345
Author(s):  
Alice Hiu Yan Cheung ◽  
Lixun Wang

The advantages of employing virtual reality tours in teaching are attributed to the virtual reality experience it provides to the students. In the case of teaching popular culture, benefits from the potential of VR tour are amplified by the empirical significance that would lead to the students’ imagination and reflection. In addition, an online VR tour suggests a flexibility that allows students to learn anyplace anytime, satisfying the need for blended learning and distance learning, which is a very critical mode of teaching and learning during the COVID-19 pandemic. This article discusses the advantages and challenges of blending “virtual reality” into the teaching of popular culture, and, furthermore, the implications of VR in tertiary education are discussed by examining the research that is conducted through the application of a VR tour in the course: Hong Kong Popular Culture. Sixty-eight students participated in the course. After implementing the VR tour, a questionnaire survey and interviews were conducted. In addition, students wrote essays to reflect on the youth culture of contemporary Hong Kong after the explanation of the tour, and these were also examined. We observed the positive responses from the students and the way in which the VR tour could enhance the learning qualities in the course on cultural studies.


2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Lacey W. Heinsberg ◽  
Daniel E. Weeks ◽  
Sheila A. Alexander ◽  
Ryan L. Minster ◽  
Paula R. Sherwood ◽  
...  

Abstract Background Following aneurysmal subarachnoid hemorrhage (aSAH), the brain is susceptible to ferroptosis, a type of iron-dependent cell death. Therapeutic intervention targeting the iron homeostasis pathway shows promise for mitigating ferroptosis and improving recovery in animal models, but little work has been conducted in humans. DNA methylation (DNAm) plays a key role in gene expression and brain function, plasticity, and injury recovery, making it a potentially useful biomarker of outcomes or therapeutic target for intervention. Therefore, in this longitudinal, observational study, we examined the relationships between trajectories of DNAm in candidate genes related to iron homeostasis and acute (cerebral vasospasm and delayed cerebral ischemia) and long-term (Glasgow Outcome Scale [GOS, unfavorable = 1–3] and death) patient outcomes after aSAH. Results Longitudinal, genome-wide DNAm data were generated from DNA extracted from post-aSAH cerebrospinal fluid (n = 260 participants). DNAm trajectories of 637 CpG sites in 36 candidate genes related to iron homeostasis were characterized over 13 days post-aSAH using group-based trajectory analysis, an unsupervised clustering method. Significant associations were identified between inferred DNAm trajectory groups at several CpG sites and acute and long-term outcomes. Among our results, cg25713625 in the STEAP3 metalloreductase gene (STEAP3) stood out. Specifically, in comparing the highest cg25713625 DNAm trajectory group with the lowest, we observed significant associations (i.e., based on p-values less than an empirical significance threshold) with unfavorable GOS at 3 and 12 months (OR = 11.7, p = 0.0006 and OR = 15.6, p = 0.0018, respectively) and death at 3 and 12 months (OR = 19.1, p = 0.0093 and OR = 12.8, p = 0.0041, respectively). These results were replicated in an independent sample (n = 100 participants) observing significant associations with GOS at 3 and 12 months (OR = 8.2, p = 0.001 and OR = 6.3, p = 0.0.0047, respectively) and death at 3 months (OR = 2.3, p = 0.008) and a suggestive association (i.e., p-value < 0.05 not meeting an empirical significance threshold) with death at 12 months (OR = 2.0, p = 0.0272). In both samples, an additive effect of the DNAm trajectory group was observed as the percentage of participants with unfavorable long-term outcomes increased substantially with higher DNAm trajectory groups. Conclusion Our results support a role for DNAm of cg25713625/STEAP3 in recovery following aSAH. Additional research is needed to further explore the role of DNAm of cg25713625/STEAP3 as a biomarker of unfavorable outcomes, or therapeutic target to improve outcomes, to translate these findings clinically.


2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Hongru Yu ◽  
Shejun Deng ◽  
Caoye Lu ◽  
Yucheng Tang ◽  
Shijun Yu ◽  
...  

The entrance and exit area of parking facilities has the characteristics of high concentration of urban traffic and prominent traffic intertwining phenomenon, which easily induces rapid congestion of mixed heterogeneous traffic at specific times and local locations and quickly spreads to the entire road section or even a larger area. In order to better understand the congestion distribution characteristics and propagation effects of access section of the parking entrance and exit from the mid and microperspective, a 5 m  ∗  lane width pixel grid is used to divide the frontage road research. It also proposes a spatially robust autoregressive model and complex network tools suitable for analysis of local traffic flow to analyze it. The results show that as spatial scale increases, the congestion propagation decreases sharply and spatial adjacency within the fourth order can account for more than 90% of the propagation; the frontage road to the entrance and exit is the place where the congestion first happens, and the congestion gradually attenuates as it propagates to the inner lane and the upstream of the road segments; the lateral congestion propagation attenuates faster, so the area affected by congestion is mainly distributed in the outermost lane. This paper can provide theoretical guidance for alleviating traffic congestion in the entrance and exit areas of parking facilities and has theoretical and empirical significance.


2021 ◽  
Vol 11 (3) ◽  
Author(s):  
Henrique Gomes

AbstractNot all symmetries are on a par. For instance, within Newtonian mechanics, we seem to have a good grasp on the empirical significance of boosts, by applying it to subsystems. This is exemplified by the thought experiment known as Galileo’s ship: the inertial state of motion of a ship is immaterial to how events unfold in the cabin, but is registered in the values of relational quantities such as the distance and velocity of the ship relative to the shore. But the significance of gauge symmetries seems less clear. For example, can gauge transformations in Yang-Mills theory—taken as mere descriptive redundancy—exhibit a similar relational empirical significance as the boosts of Galileo’s ship? This question has been debated in the last fifteen years in philosophy of physics. I will argue that the answer is ‘yes’, but only for a finite subset of gauge transformations, and under special conditions. Under those conditions, we can mathematically identify empirical significance with a failure of supervenience: the state of the Universe is not uniquely determined by the intrinsic state of its isolated subsystems. Empirical significance is therefore encoded in those relations between subsystems that stand apart from their intrinsic states.


2021 ◽  
pp. 135676672110247
Author(s):  
Yafang Bao ◽  
Emily Ma ◽  
Liqing La ◽  
Feifei Xu ◽  
Leijun Huang

Customers choosing Airbnb over a traditional hotel are looking for a different experience. Despite the popularity of Airbnb in China, little research has been devoted to examining customers’ perception and experience with this nascent form of accommodation. Through the lens of the expanded Experience Economy Model, and based on 7606 customer comments for 294 listed Airbnb accommodations in Hangzhou, China, this study explored eight aspects of customer experience—namely, entertainment, education, esthetics, escapism, interaction, home-feeling, tangible-sensorial and localness—regarding Airbnb experiences in China. Findings of this study suggested that although all eight aspects were present, there is in general a lack of entertainment and escapist experience in Airbnb accommodations in Hangzhou, suggesting meaningful directions that Airbnb accommodations need to work on. The study contributes to customer experience literature, particularly to the Experience Economy Model and also has important empirical significance.


2021 ◽  
Author(s):  
Lufeng Tai ◽  
Linnan Yan

Abstract This paper is concerned with whether the Chinese increasingly stringent environmental regulations (ER) lead to the divestment of foreign direct investment (FDI). Based on industrial firm-level panel data from 2003 to 2010, our results show that the stricter ER do not induce the divestment of FDI but rather reduce the probability of foreign firms’ withdrawal from China. Moreover, in cities with a higher degree of marketization, the ER have greatly reduced the exit probability of foreign firms. The mechanism analysis shows that due to the scale and technological advantages of foreign companies, the ER have stimulated innovation, increased the market share and profits of foreign companies. However, the ER have a greater negative impact on domestic firms’ performance. This research has theoretical and empirical significance for the economic development and environmental protection of developing countries.


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