The transdiagnostic origins of anxiety and depression during the pediatric period: Linking NIMH research domain criteria (RDoC) constructs to ecological systems

2021 ◽  
Vol 33 (5) ◽  
pp. 1599-1619
Author(s):  
Jenalee R. Doom ◽  
Michelle Rozenman ◽  
Kathryn R. Fox ◽  
Tiffany Phu ◽  
Anni R. Subar ◽  
...  
Keyword(s):  
Internalizing Problems ◽  
Ecological Factors ◽  
Ecological Systems ◽  
Anxiety And Depression ◽  
Future Research ◽  
Childhood And Adolescence ◽  
Research Domain Criteria ◽  
Affective Factors ◽  
Meta Analyses ◽  
Research Domain

AbstractIn the last decade, an abundance of research has utilized the National Institute of Mental Health (NIMH) research domain criteria (RDoC) framework to examine mechanisms underlying anxiety and depression in youth. However, relatively little work has examined how these mechanistic intrapersonal processes intersect with context during childhood and adolescence. The current paper covers reviews and meta-analyses that have linked RDoC-relevant constructs to ecological systems in internalizing problems in youth. Specifically, cognitive, biological, and affective factors within the RDoC framework were examined. Based on these reviews and some of the original empirical research they cover, we highlight the integral role of ecological factors to the RDoC framework in predicting onset and maintenance of internalizing problems in youth. Specific recommendations are provided for researchers using the RDoC framework to inform future research integrating ecological systems and development. We advocate for future research and research funding to focus on better integration of the environment and development into the RDoC framework.

scholarly journals Family process and youth internalizing problems: A triadic model of etiology and intervention

2016 ◽  
Vol 29 (1) ◽  
pp. 273-301 ◽  
Author(s):  
Jessica L. Schleider ◽  
John R. Weisz
Keyword(s):  
Parenting Styles ◽  
Internalizing Problems ◽  
Mental Health Problems ◽  
Family Processes ◽  
Family Process ◽  
Anxiety And Depression ◽  
Future Research ◽  
Targeted Interventions ◽  
Youth Anxiety ◽  
Triadic Model

AbstractDespite major advances in the development of interventions for youth anxiety and depression, approximately 30% of youths with anxiety do not respond to cognitive behavioral treatment, and youth depression treatments yield modest symptom decreases overall. Identifying networks of modifiable risk and maintenance factors that contribute to both youth anxiety and depression (i.e., internalizing problems) may enhance and broaden treatment benefits by informing the development of mechanism-targeted interventions. A particularly powerful network is the rich array of family processes linked to internalizing problems (e.g., parenting styles, parental mental health problems, and sibling relationships). Here, we propose a new theoretical model, the triadic modelof family process, to organize theory and evidence around modifiable, transdiagnostic family factors that may contribute to youth internalizing problems. We describe the model's implications for intervention, and we propose strategies for testing the model in future research. The model provides a framework for studying associations among family processes, their relation to youth internalizing problems, and family-based strategies for strengthening prevention and treatment.

scholarly journals Understanding Suicide Risk Within the Research Domain Criteria (RDoC) Framework: Insights, Challenges, and Future Research Considerations

2017 ◽  
Vol 5 (3) ◽  
pp. 568-592 ◽  
Author(s):  
Catherine R. Glenn ◽  
Christine B. Cha ◽  
Evan M. Kleiman ◽  
Matthew K. Nock
Keyword(s):  
Risk Factors ◽  
Suicidal Behavior ◽  
Suicide Risk ◽  
Future Research ◽  
Research Domain Criteria ◽  
Research Directions ◽  
Future Research Directions ◽  
Research Domain ◽  
Over Time ◽  
Broad Overview

Suicide is a leading cause of death worldwide. Prior research has focused primarily on sociodemographic and psychiatric risk factors with little improvement in the prediction or prevention of suicidal behavior over time. The Research Domain Criteria (RDoC) may be an especially useful framework for advancing research in this area. This article provides a brief and broad overview of research on suicidal behavior relating to each of the RDoC domains—highlighting the RDoC construct(s) where research has focused, the construct(s) where research is lacking, and suggestions for future research directions. We also discuss major challenges for suicide research within the RDoC framework, including the intersection of RDoC domains, interaction of domains with the environment, incorporation of developmental stage, integration of distal and proximal processes, and inclusion of suicide-specific constructs. We conclude by underscoring important considerations for future research aimed at using the RDoC framework to study suicidal behavior and other forms of psychopathology.

Future Directions in Research and Treatment of Emotion Dysregulation

2019 ◽  
pp. 476-486
Author(s):  
Theodore P. Beauchaine ◽  
Hunter Hahn ◽  
Sheila E. Crowell
Keyword(s):  
Emotion Dysregulation ◽  
Treatment Programs ◽  
Future Research ◽  
Research Domain Criteria ◽  
Future Directions ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Target Emotion ◽  
Goal Directed Behavior ◽  
Research Domain

This chapter discusses themes that emerged while editing the Oxford Handbook of Emotion Dysregulation and outlines directions for future research. Although the term emotion dysregulation has at times been used amorphously in the literature, most authors now define the phenomenon as experiences and expressions of emotion that interfere with situationally appropriate, goal-directed behavior. Situational embedding of emotion dysregulation is important given very different expectations of appropriate emotional expression across contexts and cultures. Despite emerging consensus regarding emotion dysregulation as a construct, several challenges lie ahead. Major tasks for the field are to (1) abandon implicit notions of emotion dysregulation in favor of formally operationalized definitions, such as that provided earlier; (2) maintain a clear distinction between emotion dysregulation versus mood dysregulation; (3) map transdiagnostic features of emotion dysregulation across functional domains of behavior such as those instantiated in the Research Domain Criteria matrix and, where appropriate, syndromes in the Diagnostic and Statistical Manual of Mental Disorders; (4) further develop prevention and treatment programs that systematically target emotion dysregulation across development; and (5) extend emotion dysregulation research to stigmatized groups in an effort to identify mechanisms of mental health disparities. Chapters in this volume address these issues and advance the science of emotion dysregulation in new and exciting ways.

scholarly journals A transdiagnostic perspective of constructs underlying obsessive-compulsive and related disorders: An international Delphi consensus study

2020 ◽  
Vol 54 (7) ◽  
pp. 719-731
Author(s):  
Leonardo F Fontenelle ◽  
Erin Oldenhof ◽  
Maria Eduarda Moreira-de-Oliveira ◽  
Jonathan S Abramowitz ◽  
Martin M Antony ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Performance Monitoring ◽  
Response Selection ◽  
Future Research ◽  
System Response ◽  
Research Domain Criteria ◽  
Delphi Consensus ◽  
Obsessive Compulsive ◽  
Positive Valence ◽  
Research Domain

Background: The Research Domain Criteria seeks to bridge knowledge from neuroscience with clinical practice by promoting research into valid neurocognitive phenotypes and dimensions, irrespective of symptoms and diagnoses as currently conceptualized. While the Research Domain Criteria offers a vision of future research and practice, its 39 functional constructs need refinement to better target new phenotyping efforts. This study aimed to determine which Research Domain Criteria constructs are most relevant to understanding obsessive-compulsive and related disorders, based on a consensus between experts in the field of obsessive-compulsive and related disorders. Methods: Based on a modified Delphi method, 46 experts were recruited from Australia, Africa, Asia, Europe and the Americas. Over three rounds, experts had the opportunity to review their opinion in light of feedback from the previous round, which included how their response compared to other experts and a summary of comments given. Results: Thirty-four experts completed round one, of whom 28 (82%) completed round two and 24 (71%) completed round three. At the final round, four constructs were endorsed by ⩾75% of experts as ‘primary constructs’ and therefore central to understanding obsessive-compulsive and related disorders. Of these constructs, one came from the Positive Valence System (Habit), two from the Cognitive Control System (Response Selection/Inhibition and Performance Monitoring) and the final construct was an additional item suggested by experts (Compulsivity). Conclusion: This study identified four Research Domain Criteria constructs that, according to experts, cut across different obsessive-compulsive and related disorders. These constructs represent key areas for future investigation, and may have potential implications for clinical practice in terms of diagnostic processes and therapeutic management of obsessive-compulsive and related disorders.

Multidimensional Perfectionism and Internalizing Problems: Do Teacher and Classmate Support Matter?

2016 ◽  
Vol 37 (7) ◽  
pp. 975-1003 ◽  
Author(s):  
Stephanie Secord Fredrick ◽  
Michelle Kilpatrick Demaray ◽  
Lyndsay N. Jenkins
Keyword(s):  
Social Support ◽  
Internalizing Problems ◽  
Teacher Support ◽  
Anxiety And Depression ◽  
Future Research ◽  
School Students ◽  
Maladaptive Perfectionism ◽  
High Standards ◽  
Adaptive Perfectionism ◽  
Classmate Support

Adolescent stressors coupled with environmental demands, such as pressures to achieve, might lead to negative outcomes for some students. Students who worry about their ability to meet high standards might be more at risk of internalizing problems. The current study investigated the relations among perfectionism, social support, and internalizing problems of middle school students ( N = 169). Research has established perfectionism as having maladaptive and adaptive traits. Regression analyses indicated that maladaptive perfectionism was positively related, while adaptive perfectionism was negatively related, to anxiety and depression. Adaptive perfectionists reported significantly higher levels of teacher support than maladaptive perfectionists and nonperfectionists and higher levels of classmate support than nonperfectionists. In addition, classmate support for girls and boys, and teacher support for boys, were found to buffer the relation between maladaptive perfectionism and anxiety and depression. Future research should examine social support and perfectionism and how to best provide support to maladaptive perfectionists.

A review of self-compassion as an active ingredient in the prevention and treatment of anxiety and depression in young people

2021 ◽  
Author(s):  
Sarah Egan ◽  
Clare Rees ◽  
Joanna Delalande ◽  
Danyelle Greene ◽  
Grace Fitzallen ◽  
...  
Keyword(s):  
Young People ◽  
Active Ingredient ◽  
Qualitative Interviews ◽  
Anxiety And Depression ◽  
Future Research ◽  
Inclusion Criteria ◽  
Self Compassion ◽  
Treatment And Prevention ◽  
Meta Analyses ◽  
Age Range

Previous meta-analyses have found higher self-compassion is associated with lower anxiety and depression. The aim of this study was to investigate the efficacy of self-compassion as an active ingredient in the treatment and prevention of anxiety and depression in youth. This was conducted through (i) a systematic review of the literature and (ii) qualitative consultation with young people and researchers in self-compassion. 50 studies met our inclusion criteria. Eight studies evaluated self-compassion interventions among youth aged 14-24, and the remaining studies measured the association between self-compassion and anxiety, and/or depression among this age group. Qualitative interviews were conducted with four self-compassion researchers. Interviews were also conducted in two rounds of consultation with 20 young people (M age = 18.85 years, age range 14-24 years). Higher self-compassion was related to lower symptoms of anxiety, r = -0.49, 95% CI (-0.57, -0.42), and depression, r = -.50, 95% CI (-.53, -.47). There was evidence for self-compassion interventions in decreasing anxiety and depression in young people. Consultation with young people indicated they were interested in self-compassion interventions; however, treatment should be available in a range of formats and tailored to address diversity. Self-compassion experts emphasised the importance of decreasing self-criticism as a reason why self-compassion interventions work. The importance of targeting self-criticism is supported by the preferences of young people who said they would be more likely to engage in a treatment reducing self-criticism than increasing self-kindness. Future research is required to add to the emerging evidence for self-compassion interventions decreasing symptoms of anxiety and depression in young people.

Parent–child attachment and internalizing symptoms in childhood and adolescence: A review of empirical findings and future directions

2010 ◽  
Vol 22 (1) ◽  
pp. 177-203 ◽  
Author(s):  
Laura E. Brumariu ◽  
Kathryn A. Kerns
Keyword(s):  
Internalizing Problems ◽  
Internalizing Symptoms ◽  
Attachment Security ◽  
Insecure Attachment ◽  
Anxiety And Depression ◽  
Childhood And Adolescence ◽  
Future Directions ◽  
Child Attachment ◽  
Key Questions ◽  
Parent Child

AbstractThe purpose of this paper is to evaluate the theory and evidence for the links of parent–child attachment with internalizing problems in childhood and adolescence. We address three key questions: (a) how consistent is the evidence that attachment security or insecurity is linked to internalizing symptoms, anxiety, and depression? (b) How consistent is the evidence that specific forms of insecurity are more strongly related to internalizing symptoms, anxiety, and depression than are other forms of insecurity? (c) Are associations with internalizing symptoms, anxiety, and depression consistent for mother–child and father–child attachment? The current findings are consistent with the hypothesis that insecure attachment is associated with the development of internalizing problems. The links between specific insecure attachment patterns and internalizing problems are difficult to evaluate. Father–child and mother–child attachments have a comparable impact, although there are relatively few studies of father–child attachment. No moderators consistently affect these relations. We also propose two models of how attachment insecurity may combine with other factors to lead to anxiety or depression.

scholarly journals Internalizing problems of childhood and adolescence: Prospects, pitfalls, and progress in understanding the development of anxiety and depression

2000 ◽  
Vol 12 (3) ◽  
pp. 443-466 ◽  
Author(s):  
CAROLYN ZAHN–WAXLER ◽  
BONNIE KLIMES–DOUGAN ◽  
MARCIA J. SLATTERY
Keyword(s):  
Internalizing Problems ◽  
Depressive Disorders ◽  
Developmental Psychopathology ◽  
Anxiety And Depression ◽  
Childhood And Adolescence ◽  
Systematic Analysis ◽  
Current State ◽  
New Research ◽  
Development Of Anxiety

The focus of this article is on internalizing problems that are experienced by children and adolescents. We provide an historical perspective, selectively examine the current state of knowledge, consider advances and gaps in what is known, and identify new research directions. Diagnosis, epidemiology, theory, and research first are considered separately for anxiety and depressive disorders. These internalizing problems, however, whether clinical or subclinical, share many common features and show high comorbidity rates. We emphasize the importance of systematic analysis of comorbid anxiety and depression, including their comorbidity with externalizing problems. This could lead to more valid classification of subtypes of internalizing problems and further an understanding of the diverse conditions that constitute internalized distress. We highlight the need to study anxiety and depression within a developmental psychopathology framework, as well as to include both categorical and dimensional assessments of these problems in the same research designs. This will be essential for understanding the complex interplay of biological and environmental processes that contribute to the emergence, progression, and amelioration of internalizing problems over time.

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