Assessment of heart rate variability in breath holding children by 24 hour Holter monitoring

2013 ◽  
Vol 25 (2) ◽  
pp. 317-323 ◽  
Author(s):  
Osman Yilmaz ◽  
Murat Ciftel ◽  
Kezban Ozturk ◽  
Omer Kilic ◽  
Hasan Kahveci ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Cardiac Rhythm ◽  
Holter Monitoring ◽  
Breath Holding ◽  
Control Group ◽  
Study Group ◽  
Autonomic Dysregulation ◽  
Cardiac Effects ◽  
The Mean

AbstractPurpose: Previous studies have shown that the underlying pathophysiologic mechanism in children with breath holding may be generalised autonomic dysregulation. Thus, we performed cardiac rhythm and heart rate variability analyses using 24-hour Holter monitoring to evaluate the cardiac effects of autonomic dysregulation in children with breath-holding spells. Methods: We performed cardiac rhythm and heart rate analyses using 24-hour Holter monitors to evaluate the cardiac effects of autonomic dysregulation in children during a breath-holding spell. Our study group consisted of 68 children with breath-holding spells – 56 cyanotic type and 12 pallid type – and 39 healthy controls. Results: Clinical and heart rate variability results were compared between each spell type – cyanotic or pallid – and the control group; significant differences (p<0.05) in standard deviation of all NN intervals, mean of the standard deviations of all NN intervals for all 5-minute segments, percentage of differences between adjacent RR intervals >50 ms, and square root of the mean of the sum of squares of the differences between adjacent NN intervals values were found between the pallid and cyanotic groups. Conclusions: Holter monitoring for 24 hours and heart rate variability parameters, particularly in children with pallid spells, are crucial for evaluation of cardiac rhythm changes.

scholarly journals Assessment of heart rate variability during different propofol effect site concentrations in patients with supratentorial tumours: A pilot study

2017 ◽  
Vol 04 (02) ◽  
pp. 108-113
Author(s):  
Mohit Mittal ◽  
Radhakrishnan Muthuchellappan ◽  
G. Umamaheswara Rao ◽  
K. Kavyashree ◽  
K. Vishnuprasad
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Total Power ◽  
Control Group ◽  
Baseline Heart Rate ◽  
Study Group ◽  
Intracranial Tumour ◽  
Anaesthetic Induction ◽  
Effect Site ◽  
Supratentorial Tumours

Abstract Background: Impaired autonomic function (AF) can result in adverse cardiovascular events during the perioperative period. Literature suggests that patients with intracranial space-occupying lesions experience impaired AF depending on the site of tumour and associated raised intracranial pressure (ICP). The complex interaction between general anaesthetics, AF and intracranial tumours with raised ICP has not been extensively studied. Objective: This study was aimed at evaluating the cardiac AF (in terms of heart rate variability [HRV]) in patients undergoing surgery for supratentorial tumours, at baseline and at different propofol effect site concentrations (Ce) during anaesthetic induction and the results were compared with patients undergoing non-cranial surgeries. Materials and Methods: In this prospective observational study, consecutive adult patients undergoing surgeries for supratentorial tumour (study group) and brachial plexus injury (control group) were recruited. Electrocardiogram was recorded for 5 min at three time points – before propofol induction, at propofol Ce 2 μg/ml and at Ce 4 μg/ml. Results: Forty-five patients were recruited, 24 in study group and 21 in control group. In spite of similar baseline heart rate and blood pressure, low frequency (LF), high frequency (HF) and total power were significantly higher in control group. Baseline LF/HF, though higher in patients with intracranial tumour (craniotomy: 2.2 ± 2.2, control: 1.2 ± 1.1), was not significantly different between the two groups (P = 0.197). HRV variables in both the groups changed the same way in response to the increasing propofol Ce. Conclusion: HRV measurements were significantly different at baseline between the two groups. Following propofol administration, haemodynamic changes and HRV changes were similar in both the groups and also between the two groups.

PP-336 Assessment of Heart Rate Variability in Breath Holding Children By 24 Hour Holter Monitoring

2014 ◽  
Vol 113 (7) ◽  
pp. S142-S143
Author(s):  
O. Yilmaz ◽  
M. Ciftel ◽  
O. Ceylan ◽  
H. Kahveci ◽  
O. Kilic
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Holter Monitoring ◽  
Breath Holding

scholarly journals ПОРУШЕННЯ ВАРІАБЕЛЬНОСТІ СЕРЦЕВОГО РИТМУ ЯК МЕТОД ОЦІНЮВАННЯ АДАПТАЦІЙНИХ РЕАКЦІЙ ОРГАНІЗМУ ВАГІТНИХ ПРИ НАЯВНОСТІ ШКІДЛИВИХ ЗВИЧОК

2018 ◽  
Author(s):  
V. H. Korniienko ◽  
A. S. Fitkalo
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Pregnant Women ◽  
Cardiac Rhythm ◽  
Main Group ◽  
Reproductive Age ◽  
Control Group ◽  
Cardiac Rhythm Variability ◽  
Adaptive Reactions

According to modern data, the cardiovascular system is a kind of indicator of the organism's adaptive activity, and the structure of the heart rhythm carries information about the development of adaptive reactions in response to irritating factors of the external and internal environment.The aim of the study – to investigate the functional state of the autonomic nervous system in pregnant women who have harmful habits by evaluating and analyzing the parameters of heart rate variability in order to prevent complications of non-delivery of gestational process.Materials and Methods. The study involved 73 pregnant women, 53 of them were pregnant (the main group) who had malignant habits in history. Before studying adaptive reactions in pregnant women, a study of cardiac rhythm variability was performed in practically healthy non-pregnant women of reproductive age (25.3±2.2) years). The control group consisted of 20 pregnant women without any harmful habits. Determination of heart rate variability was performed on the basis of peripheral heart rate recording, which included measuring the sequence of RR intervals for 5 minutes, followed by mathematical analysis using the PlsMntr software product.Results and Discussion. It was established that in the main group, in the complicated failure to pass the gestational process, violations of cardiac rhythm variability were detected in 59.7 % of cases. There is an increase in the frequency of very low frequency (VL F) waves (43.5 % relative to control, p<0.05), indicating a predominance of humoral and metabolic rate of regulation of the cardiac rhythm. At the threat of premature births, a decrease in the particle (LF) is observed at 36.6 %, a decrease in the share of high-frequency waves (НF) by 30.8 %. Taking into account the results of the study, one can speak of a decrease in the tone of the sympathetic and parasympathetic nervous system, reducing the influence of the reflexive vegetative level of regulation, which, in turn, indicates the depletion of regulatory mechanisms and the lack of an adaptive protective effect of n.vagus on the heart.Conclusions. Our innovative low-invasive method of evaluating the adaptive reactions of the organism through the determination and analysis of indicators of cardiac rhythm variability in pregnant women with the existing harmful habits offers us the opportunity to observe manifestations of functional stress of regulatory systems of pregnant women, preceding the development of complication of non-delivery of gestational process.

Impact of Anti-Hepatitis C Therapy on Cardiac rhythm

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Mohamed Medhat Awad ◽  
Ahmed Ibrahim El Desoky ◽  
Azza Ahmed Omran ◽  
Ghada Abdelrahman Mohamed ◽  
Ahmed Mohamed El Missiry ◽  
...  
Keyword(s):  
Heart Rate ◽  
Hepatitis C ◽  
Cardiac Rhythm ◽  
Holter Monitoring ◽  
Interval Duration ◽  
Hepatitis C Therapy ◽  
Pr Interval ◽  
The Mean ◽  
Significant Change ◽  
Post Therapy

Abstract Background The use of direct-acting antiviral (DAA) has raised some concerns about the possibilities of cardiac toxicity after US Food and Drug Administration (FDA) issued a safety announcement of serious slowing of the heart rate when Amiodarone was used with hepatitis C treatment . Aim The aim of the present study was to assess the impact of Anti-Hepatitis C Therapy on cardiac rhythm using 24 hours Holter monitoring. Methods The current study was conducted on fifty consecutive adult patients with chronic hepatitis C infection eligible for DAA therapy supplied in the outpatient clinic of Ain shams University Virology Center .Patients have received Sofosbuvir 400 mg and Daclatasvir 60 mg / day for 12 weeks. All patients underwent 24 hour Holter monitoring before and after the completion of therapy. Both recordings were compared as regards: heart rate, minimum and maximum heart rate, the presence and frequency of ectopic atrial or ventricular activity. The measurement of QRS intervals such PR, corrected QT intervals in msec. Results The pre and post analysis of the Holter recording was done with comparing different baseline and post therapy parameters, The pre and post therapy mean average heart rates were 79.44±10.14 bpm vs.79.96±8.77 bpm respectively (p = 0.534) which are non-significant changes. There is also non-significant change was observed in mean maximum and mean minimum heart rate 129.08±20.07 bpm 128.98±16.89 bpm (p = 0.964), 55.88±9.20 bpm 56.66±9.45 bpm (p = 0.457) respectively. And as regard corrected QT duration and PR interval duration, the mean pre-therapy PR interval was 154.00 ± 25.95 ms as compared to the mean post-medication PR interval duration 151.40 ± 23.82 ms (p = 0.124) and The mean premedication Corrected QT duration was 397.34 ± 29.38ms vs. post therapy 395.04 ± 30.23ms ( p = 0.403) Which showing a non-significant change of both intervals. And as regard the median pre-therapy and post medication PACs and PVCs numbers and the median pre-therapy and post medication attacks of tachycardia and bradycardia, they showed non-significant changes with P-value &gt; 0.05 . Conclusions Novel DAAs are safe to use as regards its effect on cardiac rhythm

scholarly journals The COMPARISON BETWEEN HYPERBARIC BUPIVACAINE PLUS FENTANYL AND HYPERBARIC BUPIVACAINE ALONE IN SPINAL ANESTHESIA FOR CAESAREAN SECTION

2021 ◽  
Vol 71 (3) ◽  
pp. 1033-36
Author(s):  
Fatima Iqbal ◽  
Manzoor Ahmed Faridi ◽  
Aisha Saeed ◽  
Inamullah Shah
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Caesarean Section ◽  
Arterial Blood Pressure ◽  
Mean Arterial Blood Pressure ◽  
Control Group ◽  
Study Group ◽  
Hyperbaric Bupivacaine ◽  
Arterial Blood ◽  
The Mean

Objective: To compare the result of the combination of hyperbaric bupivacaine plus fentanyl with hyperbaric bupivacaine alone in patients undergoing caesarean section in spinal anaesthesia. Study Design: Comparative, cross-sectional study. Place and Duration of Study: Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan, from Dec 2017 to Jun 2018. Methodology: After consulting the institutional ethical review committees a total of 60 females between ages 18-40 years were enrolled for caesarean section delivery. They were divided into two groups. The study group (n=30) received a subarachnoid injection of 0.5% hyperbaric bupivacaine (10mg) 2ml with 25ug of fentanyl 0.5ml and control group (n=30) was injected 0.5% hyperbaric bupivacaine 12.5mg (2.5 ml) only. Pain experienced during the procedure was assessed by using 10-point visual analogue scoring method. The mean duration of analgesia, mean arterial blood pressure and heart rate after surgery were compared between two groups. Results: The mean duration of analgesia was 206.5/min ± 6.4 in the study group and it was 163.6min ± 7.2 in the control group (p=0.001). Mean arterial BP after surgery was 92.3mmHg ± 3.8 in the study group and 88.7mmHg ± 4.1 in the control group (p=0.001). The mean heart rate recorded after surgery was 75.2/min ± 5.2 in the study group and it was 70.4/min ± 6.1 in the control group (p=0.001). Conclusions: The mean duration of analgesia was significantly longer in the study group when compared with the control group with better mean arterial blood pressure and heart rate response after Caesarean section.

scholarly journals Evaluation of Heart Rate Variability in Critically-ill Neonates

2020 ◽  
pp. 24-33
Author(s):  
Fatmah Nassar ◽  
Ashraf Ibrahim ◽  
Amr Zoair ◽  
Mohamed Rowisha
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Critically Ill ◽  
Neonatal Intensive Care ◽  
Newborn Infants ◽  
Holter Monitoring ◽  
University Hospital ◽  
Control Group ◽  
Cardiac Autonomic Dysfunction ◽  
Critically Ill Neonates

Aims: The objective of this work was to evaluate heart rate variability (HRV) in critically-ill neonates admitted to NICU, to detect the effect of different causes of critical illness on cardiac autonomic function and outcome of these neonates. Study Design: Case-control study. Place and Duration of Study: Neonatal Intensive Care Unit (NICU) of Pediatric Department, Tanta University Hospital, in the period from January 2018 to May 2019. Methodology: We included 30 neonates who were critically-ill according to Score for Neonatal Acute Physiology with Perinatal Extension II (SNAPPE-II score) as cases Group. Fifteen healthy full term neonates, matched for age and sex, were enrolled as a control group. 24-hour Holter monitoring was performed with recording and interpretation of ECG data for every neonate in the study, including analysis of HRV. Results: There was significant increase of mean HR in critically-ill neonates as compared to control group. There was significant decrease of all HRV parameters (SDNN, SDANN, SDNNI, RMSSD and PNN50) in critically-ill neonates as compared to control group (P< 0.05). Significant negative correlations between SNAPPE-II score and HRV parameters (SDNN, SDANN, SDNNI, RMSSD, PNN50) in critically-ill neonates were present, whereas there was non-significant positive correlation between SNAPPE-II score and mean heart rate. Conclusion: HRV parameters decreased significantly in critically-ill neonates admitted to NICU, denoting severe cardiac autonomic dysfunction in these sick newborn infants. HRV strongly correlated to severity (SNAPPE-II score) and outcome, with strong relation to mortality of these critically-ill neonates.

scholarly journals Dependence of Heart Rate Variability Indices on the Mean Heart Rate in Women with Well-Controlled Type 2 Diabetes

2021 ◽  
Vol 10 (19) ◽  
pp. 4386
Author(s):  
Adriana Robles-Cabrera ◽  
José M. Torres-Arellano ◽  
Ruben Fossion ◽  
Claudia Lerma
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Autonomic Nerve ◽  
Cardiac Autonomic Neuropathy ◽  
Control Group ◽  
Women Patients ◽  
Autonomic Nerve Activity ◽  
The Mean ◽  
Mean Heart Rate

Heart rate variability (HRV) is a method used to evaluate the presence of cardiac autonomic neuropathy (CAN) because it is usually attributed to oscillations in cardiac autonomic nerve activity. Recent studies in other pathologies suggest that HRV indices are strongly related to mean heart rate, and this does not depend on autonomic activity only. This study aimed to evaluate the correlation between the mean heart rate and the HRV indices in women patients with well-controlled T2DM and a control group. HRV was evaluated in 19 T2DM women and 44 healthy women during basal supine position and two maneuvers: active standing and rhythmic breathing. Time-domain (SDNN, RMSSD, pNN20) and frequency-domain (LF, HF, LF/HF) indices were obtained. Our results show that meanNN, age, and the maneuvers are the main predictors of most HRV indices, while the diabetic condition was a predictor only for pNN20. Given the known reduced HRV in patients with T2DM, it is clinically important that much of the HRV indices are dependent on heart rate irrespective of the presence of T2DM. Moreover, the multiple regression analyses evidenced the multifactorial etiology of HRV.

scholarly journals Influence of Tocolytic Therapy with Hexoprenaline on Heart Rate Variability, Lipid Spectrum and Glycemic Level in Obese Pregnant Women

2021 ◽  
Vol 6 (1) ◽  
pp. 7-12
Author(s):  
L. V. Gureeva ◽  
O. M. Chistyakova ◽  
E. K. Paramonova ◽  
O. V. Radkov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Pregnant Women ◽  
Low Frequency ◽  
Holter Monitoring ◽  
Serum Glucose ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Glycemic Level ◽  
Lipid Spectrum

Background. Obesity is associated with the risk of spontaneous preterm birth. Hexoprenaline is the effective and most widely used tocolytic agent, possessing however a significant number of side effects. The effect of hexoprenaline tocolysis on heart rate variability, lipid spectrum and glycaemia level in obese pregnant women remain unexplored.Aim of the research. To study the effect of tocolytic therapy with hexoprenaline on heart rate variability, lipid spectrum and glycemic level in obese pregnant women.Materials and methods. The study included two groups of pregnant women with threatened preterm labor who received tocolysis with hexoprenaline. One group consisted of 68 obese patients, the other – 72 non-obese pregnant women (control group). Patients underwent Holter monitoring. Fasting serum glucose and lipids spectrum were measured before starting tocolytic therapy and after 24 hours of tocolysis.Results. In obese pregnant women with hexoprenaline infusion, the heart rate, the 24-hours number of supraventricular extrasystoles and ventricular extrasystoles during the day are significantly higher. Frequency domain parameters, very low frequency during the day, low frequency at night and 24-hours high frequency were significantly decreased than in control group. After a day of tocolysis in obese pregnant women, the level of total cholesterol, low density lipoproteins, triglycerides, and glucose significantly increases when compared with the results before therapy. For patients in the control group treated with hexoprenaline, only the concentration of high-density lipoproteins is increased.Conclusion. Obesity in pregnant women receiving hexoprenaline tocolysis is associated with low heart rate variability and an increase in the number of cardiac arrhythmias, as well as lipid disorders and an increase in glucose level.

scholarly journals Post-surgical heart rate variability in patients with brain tumor and epileptic seizures

2017 ◽  
Vol 98 (1) ◽  
pp. 38-44
Author(s):  
A A Miranda ◽  
V A Zhadnov ◽  
A A Magerramov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Brain Tumor ◽  
Brain Tumors ◽  
Tumor Resection ◽  
Epileptic Seizures ◽  
Control Group ◽  
Epilepsy Syndrome ◽  
Study Group ◽  
Neurosurgical Department

Aim. To identify post-surgical perculiarities of heart rate variability in patients with brain tumors and symptomatic epilepsy.Methods. The study group consisted of 85 patients (43 males and 42 females) aged 22 to 83 years admitted to neurosurgical department of Ryazan regional clinical hospital with brain tumor. The control group consisted of 20 relatively healthy individuals. The study group was divided into 2 subgroups of patients with brain tumor associated with symptomatic epilepsy and brain tumors without epileptic seizures. Five-minute ECGs in 3 functional probes (baseline, hyperventilation and post-hyperventilation) before and after craniotomy with tumor resection were recorded. The following statistical analysis of time and frequency parameters of heart rate variability was performed.Results. Statistically significant differences in heart rate variability in pre- and post-surgical periods were found only in patients with epilepsy syndrome caused by brain tumor: mode increased by 11% in baseline and post-hyperventilation probes. Coefficient of variation and standard deviation were decreased by 29% in hyperventilation probe, index of centralization decreased by 60% in baseline probe and by 42% in post-hyperventilation probe. Statistically significant increase of high frequency power component by 46% was registered after surgical intervention in baseline probe and by 10% in post-hyperventilation probe. As opposed to this in the subgroup of patients with brain tumors and without epilepsy this parameter decresed by 10% in baseline probe.Conclusion. The obtained results demonstrate significant post-surgical improvement of autonomic nervous system homeostasis and restoration of cardiovascular functional reserves in patients with brain tumor associated with epilepsy compared to those with no epileptic seizures.

scholarly journals VEGETATIVE REGULATION OF CARDIAC FUNCTION IN DIFFUSE TOXIC GOITER ASSOCIATED WITH PATHOGENETIC THERAPY

2016 ◽  
pp. 52-55
Author(s):  
E. V. Tsitko ◽  
Е. G. Маlауеvа ◽  
I. P. Yatsenko ◽  
E. L. Tsitko ◽  
I. A. Hudyakov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Cardiac Function ◽  
Holter Monitoring ◽  
Control Group ◽  
Thyroid Status ◽  
Vegetative Nervous System ◽  
Pathogenetic Therapy ◽  
Vegetative Regulation ◽  
Toxic Goiter

Objective: to study the vegetative regulation of cardiac function by means of Holter monitoring in patients diagnosed with diffuse toxic goiter associated with therapy with tireostatics and beta adrenoblockers (рropranololum, bisoprolol). Material and methods . 82 patients diagnosed with a diffuse toxic goiter aged 18-60, out of them 24 men and 58 women participated in the study. The patients were divided into two groups: the first group (46 patients) took non-selective beta adrenoblocker Propranololum (Anaprilin), the second group (36 patients) took beta1-adrenoblocker Bisoprolol. The control group included 30 almost healthy volunteers. All the patients were performed Holter monitoring with the assessment of heart rate variability, their thyroid status was studied. Results. We have done the comparative analysis of the thyroid status in the groups of the patients with diffuse toxic goiter following different schemes of pathogenetic therapy. We have analyzed the data of Holter monitoring with the assessment of heart rate variability related to the intake of cardioselective and non-selective beta adrenoblockers. Conclusion . Patients with compensated thyrotoxicosis taking Bisoprolol at a dose of 5 mg/day and Thiamazolum of 15 mg/day have signs of vegetative imbalance in the form of dominance of sympathetic section of the vegetative nervous system. When the compensation of thyrotoxicosis is achieved in patients using the scheme of 40 mg/day of Anaprilin and 20mg/day of Thiamazolum, the vegetative regulation of cardiac function is characterized by vegetative balance. The correction of medicamentous therapy of vegetative imbalance is possible taking into account results of Holter monitoring.

Sign in / Sign up

Export Citation Format

Share Document