scholarly journals Post-surgical heart rate variability in patients with brain tumor and epileptic seizures

2017 ◽  
Vol 98 (1) ◽  
pp. 38-44
Author(s):  
A A Miranda ◽  
V A Zhadnov ◽  
A A Magerramov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Brain Tumor ◽  
Brain Tumors ◽  
Tumor Resection ◽  
Epileptic Seizures ◽  
Control Group ◽  
Epilepsy Syndrome ◽  
Study Group ◽  
Neurosurgical Department

Aim. To identify post-surgical perculiarities of heart rate variability in patients with brain tumors and symptomatic epilepsy.Methods. The study group consisted of 85 patients (43 males and 42 females) aged 22 to 83 years admitted to neurosurgical department of Ryazan regional clinical hospital with brain tumor. The control group consisted of 20 relatively healthy individuals. The study group was divided into 2 subgroups of patients with brain tumor associated with symptomatic epilepsy and brain tumors without epileptic seizures. Five-minute ECGs in 3 functional probes (baseline, hyperventilation and post-hyperventilation) before and after craniotomy with tumor resection were recorded. The following statistical analysis of time and frequency parameters of heart rate variability was performed.Results. Statistically significant differences in heart rate variability in pre- and post-surgical periods were found only in patients with epilepsy syndrome caused by brain tumor: mode increased by 11% in baseline and post-hyperventilation probes. Coefficient of variation and standard deviation were decreased by 29% in hyperventilation probe, index of centralization decreased by 60% in baseline probe and by 42% in post-hyperventilation probe. Statistically significant increase of high frequency power component by 46% was registered after surgical intervention in baseline probe and by 10% in post-hyperventilation probe. As opposed to this in the subgroup of patients with brain tumors and without epilepsy this parameter decresed by 10% in baseline probe.Conclusion. The obtained results demonstrate significant post-surgical improvement of autonomic nervous system homeostasis and restoration of cardiovascular functional reserves in patients with brain tumor associated with epilepsy compared to those with no epileptic seizures.

scholarly journals Assessment of heart rate variability during different propofol effect site concentrations in patients with supratentorial tumours: A pilot study

2017 ◽  
Vol 04 (02) ◽  
pp. 108-113
Author(s):  
Mohit Mittal ◽  
Radhakrishnan Muthuchellappan ◽  
G. Umamaheswara Rao ◽  
K. Kavyashree ◽  
K. Vishnuprasad
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Total Power ◽  
Control Group ◽  
Baseline Heart Rate ◽  
Study Group ◽  
Intracranial Tumour ◽  
Anaesthetic Induction ◽  
Effect Site ◽  
Supratentorial Tumours

Abstract Background: Impaired autonomic function (AF) can result in adverse cardiovascular events during the perioperative period. Literature suggests that patients with intracranial space-occupying lesions experience impaired AF depending on the site of tumour and associated raised intracranial pressure (ICP). The complex interaction between general anaesthetics, AF and intracranial tumours with raised ICP has not been extensively studied. Objective: This study was aimed at evaluating the cardiac AF (in terms of heart rate variability [HRV]) in patients undergoing surgery for supratentorial tumours, at baseline and at different propofol effect site concentrations (Ce) during anaesthetic induction and the results were compared with patients undergoing non-cranial surgeries. Materials and Methods: In this prospective observational study, consecutive adult patients undergoing surgeries for supratentorial tumour (study group) and brachial plexus injury (control group) were recruited. Electrocardiogram was recorded for 5 min at three time points – before propofol induction, at propofol Ce 2 μg/ml and at Ce 4 μg/ml. Results: Forty-five patients were recruited, 24 in study group and 21 in control group. In spite of similar baseline heart rate and blood pressure, low frequency (LF), high frequency (HF) and total power were significantly higher in control group. Baseline LF/HF, though higher in patients with intracranial tumour (craniotomy: 2.2 ± 2.2, control: 1.2 ± 1.1), was not significantly different between the two groups (P = 0.197). HRV variables in both the groups changed the same way in response to the increasing propofol Ce. Conclusion: HRV measurements were significantly different at baseline between the two groups. Following propofol administration, haemodynamic changes and HRV changes were similar in both the groups and also between the two groups.

Assessment of heart rate variability in breath holding children by 24 hour Holter monitoring

2013 ◽  
Vol 25 (2) ◽  
pp. 317-323 ◽  
Author(s):  
Osman Yilmaz ◽  
Murat Ciftel ◽  
Kezban Ozturk ◽  
Omer Kilic ◽  
Hasan Kahveci ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Cardiac Rhythm ◽  
Holter Monitoring ◽  
Breath Holding ◽  
Control Group ◽  
Study Group ◽  
Autonomic Dysregulation ◽  
Cardiac Effects ◽  
The Mean

AbstractPurpose: Previous studies have shown that the underlying pathophysiologic mechanism in children with breath holding may be generalised autonomic dysregulation. Thus, we performed cardiac rhythm and heart rate variability analyses using 24-hour Holter monitoring to evaluate the cardiac effects of autonomic dysregulation in children with breath-holding spells. Methods: We performed cardiac rhythm and heart rate analyses using 24-hour Holter monitors to evaluate the cardiac effects of autonomic dysregulation in children during a breath-holding spell. Our study group consisted of 68 children with breath-holding spells – 56 cyanotic type and 12 pallid type – and 39 healthy controls. Results: Clinical and heart rate variability results were compared between each spell type – cyanotic or pallid – and the control group; significant differences (p<0.05) in standard deviation of all NN intervals, mean of the standard deviations of all NN intervals for all 5-minute segments, percentage of differences between adjacent RR intervals >50 ms, and square root of the mean of the sum of squares of the differences between adjacent NN intervals values were found between the pallid and cyanotic groups. Conclusions: Holter monitoring for 24 hours and heart rate variability parameters, particularly in children with pallid spells, are crucial for evaluation of cardiac rhythm changes.

scholarly journals PROGNOSIS OF SYMPTOMATIC EPILEPSY DEVELOPMENT IN PATIENTS WITH BRAIN TUMORS THROUGH ANALYSIS OF NEUROPHYSIOLOGICAL PARAMETERS AND BINARY LOGISTIC REGRESSION

2017 ◽  
Vol 25 (2) ◽  
pp. 223-236 ◽  
Author(s):  
A. A. Мiranda ◽  
R. A. Zorin ◽  
V. A. Zhadnov
Keyword(s):  
Logistic Regression ◽  
Brain Tumor ◽  
Brain Tumors ◽  
Average Power ◽  
Total Power ◽  
Control Group ◽  
Primary Group ◽  
Neurosurgical Department ◽  
Symptomatic Epilepsy ◽  
Predictor Factors

Aim: this study was aimed at identifying prognostic potential of electroencephalo- graphic and cardiointervalometric neurophysiological parameters using logistic regression modeling in patients with brain tumors manifesting with symptomatic epilepsy. Methods: the primary group of participants in the study consisted of 88 patients, aged 22 to 83 years admitted at Ryazan State regional hospital neurosurgical department with brain tumor as the admitting diagnosis. The control group consisted of 20 relatively healthy individuals of equal gender distribution. The primary group was further subdivided into groups of patients with brain tumor associated epilepsy and brain tumors with no epileptic seizures. Five minute electrocardiogram as well as electroencephalograms were recorded in 3 functional probes (baseline, hyperventilation and post-hyperventilation) on admission followed by statistical correlational analysis and logistic regression. Results: based on significantly strong correlations the selected electroencephalogram predictor factors included Average power of the delta wave diapazon in F3-A1 and O2-A2 during hyperventilation probe as well as Mode (Mo) and very low frequency component of total power (%VLF) cardiointer- val parameters during post-hyperventilation probe. Selected predictors used in the logistic regression model were able to predict possible prognosis in patients with brain tumor induced epilepsy with 73% sensitivity and 96% specificity. Conclusion: logistic regression analysis of pre-defined neurophysiological predictor factors is perspective in neurooncological patients including patients with brain tumor induced epilepsy in terms of its clinical prognostic value and structuring of complex and effective treatment schemes.

scholarly journals Clinical, neuroimaging and eeg correlations in epileptic syndrome in patients with a brain tumor

2019 ◽  
pp. 132-134
Author(s):  
Sh. B. Gafurov
Keyword(s):  
Brain Tumor ◽  
Brain Tumors ◽  
Epileptic Seizures ◽  
Control Group ◽  
Partial Seizures ◽  
Convulsive Disorder ◽  
Eeg Activity ◽  
Oncological Patients ◽  
The Brain ◽  
Early Seizures

The results of the survey of 193 neuro-oncological patients with epileptic seizures are showed. The control group consisted of 97 patients with brain tumors without the development of epileptic seizures. It is found that in patients with the development of epileptic seizures as a first symptom of cerebral tumors predominated simple partial seizures. Early seizures occurred more frequently in lesions of the left hemisphere of the brain with the formation of focal abnormal EEG activity in the same hemisphere of the brain. Convulsive disorder prevailed in the localization of intracerebral tumors with caudal direction of its growth.

scholarly journals Heart rate variability analysis for the identification of the preictal interval in patients with drug-resistant epilepsy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Adriana Leal ◽  
Mauro F. Pinto ◽  
Fábio Lopes ◽  
Anna M. Bianchi ◽  
Jorge Henriques ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Linear Time ◽  
Epileptic Seizures ◽  
Heart Rate Variability Analysis ◽  
Drug Resistant ◽  
Clustering Methods ◽  
Temporal Lobe Seizures ◽  
New Perspective ◽  
Drug Resistant Epilepsy

AbstractElectrocardiogram (ECG) recordings, lasting hours before epileptic seizures, have been studied in the search for evidence of the existence of a preictal interval that follows a normal ECG trace and precedes the seizure’s clinical manifestation. The preictal interval has not yet been clinically parametrized. Furthermore, the duration of this interval varies for seizures both among patients and from the same patient. In this study, we performed a heart rate variability (HRV) analysis to investigate the discriminative power of the features of HRV in the identification of the preictal interval. HRV information extracted from the linear time and frequency domains as well as from nonlinear dynamics were analysed. We inspected data from 238 temporal lobe seizures recorded from 41 patients with drug-resistant epilepsy from the EPILEPSIAE database. Unsupervised methods were applied to the HRV feature dataset, thus leading to a new perspective in preictal interval characterization. Distinguishable preictal behaviour was exhibited by 41% of the seizures and 90% of the patients. Half of the preictal intervals were identified in the 40 min before seizure onset. The results demonstrate the potential of applying clustering methods to HRV features to deepen the current understanding of the preictal state.

scholarly journals Cardiac Parasympathetic Withdrawal and Sympathetic Activity: Effect of Heat Exposure on Heart Rate Variability

2021 ◽  
Vol 18 (11) ◽  
pp. 5934
Author(s):  
Oriol Abellán-Aynés ◽  
Pedro Manonelles ◽  
Fernando Alacid
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Environmental Conditions ◽  
Sympathetic Activity ◽  
Heat Exposure ◽  
Repeated Measurements ◽  
Control Group ◽  
Poincaré Plot ◽  
Activity Effect ◽  
And Control

(1) Background: Research on heart rate variability has increased in recent years and the temperature has not been controlled in some studies assessing repeated measurements. This study aimed to analyze how heart rate variability may change based on environmental temperature during measurement depending on parasympathetic and sympathetic activity variations. (2) Methods: A total of 22 volunteers participated in this study divided into an experimental (n = 12) and control group (n = 10). Each participant was assessed randomly under two different environmental conditions for the experimental group (19 °C and 35 °C) and two identical environmental conditions for the control group (19 °C). During the procedure, heart rate variability measurements were carried out for 10 min. (3) Results: Significantly changes were observed for time and frequency domains as well as Poincaré plot variables after heat exposure (p < 0.05). These findings were not observed in the control group, whose conditions between measurements did not change. (4) Conclusions: The reduction of heart rate variability due to exposure to hot conditions appears to be produced mostly by a parasympathetic withdrawal rather than a sympathetic activation. Therefore, if consecutive measurements have to be carried out, these should always be done under the same temperature conditions.

scholarly journals Effect of intravenous oxycodone on the physiologic responses to extubation following general anesthesia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Menglu Jiang ◽  
Jiawei Ji ◽  
Xin Li ◽  
Zhenqing Liu
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
General Anesthesia ◽  
Control Group ◽  
Study Group ◽  
Clinical Trial Registry ◽  
Blood Oxygen Saturation ◽  
Blood Concentrations ◽  
Number Of Patients ◽  
Blood Hormones

Abstract Background Endotracheal intubation and extubation may cause undesirable hemodynamic changes. Intravenous oxycodone has recently been introduced and used for relieving hemodynamic alterations in response to intubation, but there is insufficient information regarding its application in stabilizing hemodynamics during extubation in the patients emerging from general anesthesia. Methods One hundred patients, who had undergone assorted laparoscopic surgeries under general anesthesia, were randomly assigned to Control group (saline injection, 50 cases) and Study group (intravenous injection of 0.08 mg/kg oxycodone immediately after completion of the surgical procedure, 50 cases). Blood pressure, heart rate, blood oxygen saturation (SpO2) as well as blood concentrations of epinephrine, norepinephrine, and cortisol were recorded or measured immediately before extubation (T0), during extubation (T1), as well as one minute (T2), 5 min (T3), and 10 min after extubation (T4). In addition, coughing and restlessness, time of eye-opening, and duration from completing surgery to extubation as well as Ramsay Sedation Scale were analyzed. Results Blood pressure and heart rate as well as blood concentrations of epinephrine, norepinephrine, and cortisol were significantly higher in the Control group compared with the Study group at the time of extubation as well as 1, 5, and 10 min after extubation (P < 0.05). When the patients emerged from general anesthesia, 70 % of the Control group had cough, which was significantly higher than that of Study group (40 %, P < 0.05). Significantly higher number of patients manifested restlessness in the Control group before (40 %) and after extubation (20 %) compared with that in the Study group (20 and 2 %, respectively, P < 0.05). In addition, patients of Control group had lower Ramsay score at extubation (1.7 ± 0.7) as well as 30 min after extubation (2.4 ± 0.9) compared to that of the patients of Study group (2.2 ± 0.9, and 3.0 ± 0.8, respectively, P = 0.003 and 0.001). Conclusions Intravenous oxycodone attenuated alterations of hemodynamics and blood hormones associated with extubation during emergence from general anesthesia. Trial registration Chinese Clinical Trial Registry: ChiCTR2000040370 (registration date: 11-28-2020) “‘retrospectively registered”.

scholarly journals Effect of Acupuncture on Heart Rate Variability: A Systematic Review

2014 ◽  
Vol 2014 ◽  
pp. 1-19 ◽  
Author(s):  
Joanne W. Y. Chung ◽  
Vincent C. M. Yan ◽  
Hongwei Zhang
Keyword(s):  
Systematic Review ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
High Frequency ◽  
Healthy Subjects ◽  
Keyword Search ◽  
Data Extraction ◽  
Meta Analysis ◽  
Low Frequency ◽  
Control Group

Aim.To summarize all relevant trials and critically evaluate the effect of acupuncture on heart rate variability (HRV).Method.This was a systematic review with meta-analysis. Keyword search was conducted in 7 databases for randomized controlled trials (RCTs). Data extraction and risk of bias were done.Results.Fourteen included studies showed a decreasing effect of acupuncture on low frequency (LF) and low frequency to high frequency ratio (LF/HF ratio) of HRV for nonhealthy subjects and on normalized low frequency (LF norm) for healthy subjects. The overall effect was in favour of the sham/control group for high frequency (HF) in nonhealthy subjects and for normalized high frequency (HF norm) in healthy subjects. Significant decreasing effect on HF and LF/HF ratio of HRV when acupuncture was performed on ST36 among healthy subjects and PC6 among both healthy and nonhealthy subjects, respectively.Discussion.This study partially supports the possible effect of acupuncture in modulating the LF of HRV in both healthy and nonhealthy subjects, while previous review reported that acupuncture did not have any convincing effect on HRV in healthy subjects. More published work is needed in this area to determine if HRV can be an indicator of the therapeutic effect of acupuncture.

Heart Rate Variability And Respiratory Muscle Strength In Patients With Type Ii Diabetes Practicing Pilates: A Randomized Clinical Trial

2021 ◽  
Vol 17 ◽  
Author(s):  
Samara Sousa Vasconcelos Gouveia ◽  
Guilherme Pertinni de Morais Gouveia ◽  
Leydnaya Maria Souza ◽  
Bruno Cunha da Costa ◽  
Gustavo Henrique Melo Sousa ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Muscle Strength ◽  
Normal Distribution ◽  
Randomized Clinical Trial ◽  
Respiratory Muscle ◽  
Control Group ◽  
Respiratory Muscle Strength

Purpose: This study aimed to analyze the effect of a Pilates protocol on respiratory muscle strength and heart rate variability (HRV) in patients with type 2 diabetes. Method: A randomized clinical trial (RBR-2gc2qj) was conducted with a type 2 diabetic target population. Patients practiced the Pilates protocol for 8 weeks, with two visits per week. The variables tested were maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), and HRV (time and frequency domains). All variables were tested for normal distribution. Using SPSS 21.0, analysis of variance was performed for variables with normal distribution, and the Wilcoxon and Friedman tests were used for variables that did not show a normal distribution, with a 5% significance level. Results: Forty-four participants were included in the study (intervention group: 22; control group: 22; mean age: 61.23 ± 8.49 years), most of whom were female (77.3%), married or in a consensual union (59.1%), had complete literacy (31.8%), and had an average body mass index of 26.96 ± 4.35 kg/m2. There were no significant differences in MIP and MEP before and after the protocol between the intervention and control groups. Regarding HRV, there were significant differences in autonomic modulation, especially between the moments before and during exercise and between the moments during and after exercise; however, it was not possible to determine which system (sympathetic or parasympathetic) is most involved in these changes. Conclusion: The exercise protocol based on the Pilates method did not alter respiratory muscle strength but promoted changes in HRV, especially between the moments before and during exercise and during and after exercise.

Effect of short-term mental stress on time- domain indices of heart rate variability in obese individuals – A case- control study

Biomedicine ◽  
2021 ◽  
Vol 41 (2) ◽  
pp. 274-277
Author(s):  
Priya S.A. ◽  
R. Rajalakshmi
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Neuronal Activity ◽  
Time Domain ◽  
Mental Stress ◽  
Mental Arithmetic ◽  
High Body Mass Index ◽  
Control Group ◽  
Stress Task ◽  
The Individual

  Introduction and Aim: Mental stress may impact dramatically on dynamic autonomic control on heart. Many studies have demonstrated association of high body mass index (BMI) with greater risk for cardiovascular disease with disturbance in autonomic neuronal activity. Analysis of Heart rate variability (HRV)during acute mental stress assesses the autonomic status of the individual. Hence, we aimed to study the effect of acute mental stress on time domain measures in obese adults.   Materials and Methods:Sixty male volunteers of 30 each in study group (obese individuals) and control group (non-obese individuals) were recruited for the study. A basal recording of ECG in lead II was done on all the individuals. Then they underwent mental arithmetic stress task for 5 minutes during which again ECG was recorded. The change in time domain measures of HRV during rest and stress task was analyzed and compared between both the groups.   Results: Analysis of time domain measures of HRV revealed a statistically significant increase (p ? 0.001) in mean heart rate in both obese and non-obese individuals, while rMSSD(root mean square differences of successive RR interval) and SDNN (standard deviation of all NN intervals) showed a statistically significant (p? 0.001) decrease in obese individuals and non-obese individuals did not show any statistically significant change during the mental stress task.   Conclusion: In response to acute mental stress there was increased heart rate in both the groups. But the autonomic neuronal activity differed by way of sympathetic dominance in non-obese individuals and parasympathetic withdrawal in obese individuals.  

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