scholarly journals ПОРУШЕННЯ ВАРІАБЕЛЬНОСТІ СЕРЦЕВОГО РИТМУ ЯК МЕТОД ОЦІНЮВАННЯ АДАПТАЦІЙНИХ РЕАКЦІЙ ОРГАНІЗМУ ВАГІТНИХ ПРИ НАЯВНОСТІ ШКІДЛИВИХ ЗВИЧОК

2018 ◽  
Author(s):  
V. H. Korniienko ◽  
A. S. Fitkalo
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Pregnant Women ◽  
Cardiac Rhythm ◽  
Main Group ◽  
Reproductive Age ◽  
Control Group ◽  
Cardiac Rhythm Variability ◽  
Adaptive Reactions

According to modern data, the cardiovascular system is a kind of indicator of the organism's adaptive activity, and the structure of the heart rhythm carries information about the development of adaptive reactions in response to irritating factors of the external and internal environment.The aim of the study – to investigate the functional state of the autonomic nervous system in pregnant women who have harmful habits by evaluating and analyzing the parameters of heart rate variability in order to prevent complications of non-delivery of gestational process.Materials and Methods. The study involved 73 pregnant women, 53 of them were pregnant (the main group) who had malignant habits in history. Before studying adaptive reactions in pregnant women, a study of cardiac rhythm variability was performed in practically healthy non-pregnant women of reproductive age (25.3±2.2) years). The control group consisted of 20 pregnant women without any harmful habits. Determination of heart rate variability was performed on the basis of peripheral heart rate recording, which included measuring the sequence of RR intervals for 5 minutes, followed by mathematical analysis using the PlsMntr software product.Results and Discussion. It was established that in the main group, in the complicated failure to pass the gestational process, violations of cardiac rhythm variability were detected in 59.7 % of cases. There is an increase in the frequency of very low frequency (VL F) waves (43.5 % relative to control, p<0.05), indicating a predominance of humoral and metabolic rate of regulation of the cardiac rhythm. At the threat of premature births, a decrease in the particle (LF) is observed at 36.6 %, a decrease in the share of high-frequency waves (НF) by 30.8 %. Taking into account the results of the study, one can speak of a decrease in the tone of the sympathetic and parasympathetic nervous system, reducing the influence of the reflexive vegetative level of regulation, which, in turn, indicates the depletion of regulatory mechanisms and the lack of an adaptive protective effect of n.vagus on the heart.Conclusions. Our innovative low-invasive method of evaluating the adaptive reactions of the organism through the determination and analysis of indicators of cardiac rhythm variability in pregnant women with the existing harmful habits offers us the opportunity to observe manifestations of functional stress of regulatory systems of pregnant women, preceding the development of complication of non-delivery of gestational process.

Gestational process and labour activity in women with different types of autonomic regulation

2019 ◽  
pp. 27-33
Author(s):  
V.V. Kaminskyy ◽  
◽  
R.R. Tkachuk ◽  
◽  
◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Pregnant Women ◽  
Main Group ◽  
Autonomic Regulation ◽  
Control Group ◽  
Different Types ◽  
Labor Abnormalities

The objective: is to analyze the frequency of gestational complications and labor abnormalities in pregnant women with different types of autonomic regulation disorders. Materials and methods. 129 women were examined. The type of autonomic regulation was determined by recording the time and spectral parameters of heart rate variability by computer cardiointervalography with use of CardioLab Bebicard diagnostic system. The main group consisted of 66 pregnant women with established autonomic regulation disorders. 63 patients with a normal autonomic state, a balanced level of sympathetic and parasympathetic activity formed a control group. To assess the status of the mother-placenta-fetus, an ultrasound examination with doplerometry was performed. Results. A significant increase of the central regulatory activity in pregnant women with autonomic dysfunction was established. The cardiointervalography indicate a balanced activity of the autonomic nervous system in the control group. The gestational complications were significantly more frequent in women of the main group in the context of detected autonomic dysfunction than in the control group. Labor anomalies were more common in pregnant women of the main group. Women with high parasympathetic astivity noted an increased frequency of labor dystocia. In patients with a superiority of sympathetic and humoral regulation, an increased frequency of labour activity weakness was observed. The fast deliveries often determined in pregnant women with decreased activity of both departments of autonomic nervous system. The incidence of urgent caesarian deliveries was significantly higher in the main group, including due to the ineffectiveness of the medical correction of labor abnormalities. Conclusions. The cardiointervalography is informative for the diagnosis of autonomous regulation and adaptive disorders, which may be the prerequisites for the gestational complications and labor abnormalities development. Using the heart rate variability analys is in pregnant women will improve the early prediction of gestational pathology and pathological birth process, reduce the risk of obstetric and perinatal complications. Key words: heart rate variability, autonomic regulation, gestational complications, labor activity abnormalities.

scholarly journals Assessment of heart rate variability and tone of the autonomic nervous system in puberty-aged children with undifferentiated connective tissue dysplasia

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
O V Sidorovich ◽  
S Y U Elizarova ◽  
A V Khizhnyak ◽  
N A Kuznetsova ◽  
E E Prosova
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Connective Tissue ◽  
Control Group ◽  
Healthy Children ◽  
Autonomic Nervous ◽  
Connective Tissue Dysplasia ◽  
End Of Puberty

Abstract   Within the framework of the research into pathological conditions and syndromes associated with undifferentiated connective tissue dysplasia (UCTD), an emphasis needs to be placed on the changes in heart rhythm. In puberty, the severity of neurovegetative disorders caused by the presence of UCTD might increase manifold. The features of heart rate variability (HRV) in pubertal children against the background of UCTD have been studied insufficiently and require more detailed analysis. This study aims to assess heart rate variability and tone of the autonomic nervous system (ANS) in puberty-aged children with UCTD. Two groups of children were examined, with methods including electrocardiography and cardiointervalography. The main group consisted of 36 puberty-aged children with UCTD, the control group consisted of 30 healthy children. ANS tone was assessed based on the HRV. In the control group of children aged 11, the value of variation range (VR) was 0.18±0.4, mode amplitude (MA) 35.2±2.4, stress index (IN) 72.8±4.3, which corresponds to the state of vegetative balance. As the puberty progresses, the state of eutonia is replaced by the activation of the sympathetic division of the ANS, which becomes most pronounced at the age of 13 years. In the control group of children aged 13, the value of VR was 0.08±0.02, MA 61.7±2.1, SI 210.6±8.6, which corresponds to moderate sympathicotonia. By the end of puberty, in healthy children, the severity of sympathetic activation begins to decrease, and at the age of 15 years, vegetative balance is again observed. However, this pattern is violated in children with UCTD. Upon entering puberty, moderate activation of the sympathetic division of the ANS is already observed in children with UCTD. At the age of 11 years in this group, the value of VR is 0.06±0.02, MA 72.4±3.1, SI 211.2±8.6. At the age of 13, pronounced sympathicotonia is observed, which is confirmed by the values of VR - 0.04±0.01, MA 80.2±4.3 and SI 34.3±14.7. By the end of puberty in children with UCTD, in contrast to the control group, the analyzed parameters indicate not an equilibrium of the ANS, but the predominance of parasympathetic activation. The research provides an insight into heart rate variability in puberty-aged children with UCTD. It was established that healthy children enter puberty in a state of equilibrium of the autonomic nervous system, which in the middle of puberty is replaced by moderate sympathicotonia, and then returns to its original values. Children with the presence of UCTD enter puberty with moderately pronounced sympathicotonia, which gradually increases to pronounced values and is replaced by moderate vagotonia. FUNDunding Acknowledgement Type of funding sources: None.

Assessment of heart rate variability in breath holding children by 24 hour Holter monitoring

2013 ◽  
Vol 25 (2) ◽  
pp. 317-323 ◽  
Author(s):  
Osman Yilmaz ◽  
Murat Ciftel ◽  
Kezban Ozturk ◽  
Omer Kilic ◽  
Hasan Kahveci ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Cardiac Rhythm ◽  
Holter Monitoring ◽  
Breath Holding ◽  
Control Group ◽  
Study Group ◽  
Autonomic Dysregulation ◽  
Cardiac Effects ◽  
The Mean

AbstractPurpose: Previous studies have shown that the underlying pathophysiologic mechanism in children with breath holding may be generalised autonomic dysregulation. Thus, we performed cardiac rhythm and heart rate variability analyses using 24-hour Holter monitoring to evaluate the cardiac effects of autonomic dysregulation in children with breath-holding spells. Methods: We performed cardiac rhythm and heart rate analyses using 24-hour Holter monitors to evaluate the cardiac effects of autonomic dysregulation in children during a breath-holding spell. Our study group consisted of 68 children with breath-holding spells – 56 cyanotic type and 12 pallid type – and 39 healthy controls. Results: Clinical and heart rate variability results were compared between each spell type – cyanotic or pallid – and the control group; significant differences (p<0.05) in standard deviation of all NN intervals, mean of the standard deviations of all NN intervals for all 5-minute segments, percentage of differences between adjacent RR intervals >50 ms, and square root of the mean of the sum of squares of the differences between adjacent NN intervals values were found between the pallid and cyanotic groups. Conclusions: Holter monitoring for 24 hours and heart rate variability parameters, particularly in children with pallid spells, are crucial for evaluation of cardiac rhythm changes.

scholarly journals Heart rate variability in laparoscopic hysterectomy depending on different types of anesthesia

2021 ◽  
Vol 3 ◽  
pp. 37-40
Author(s):  
S. Zaychenko ◽  
R. Tkachenko
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Laparoscopic Hysterectomy ◽  
Control Group ◽  
Autonomic Nervous ◽  
Stress Protection ◽  
Different Types

The objective: was to evaluate the effectiveness of various anesthesia options for laparoscopic hysterectomy, including low-opioid (LOA) and opioid-free anesthesia (OFA) by studying the dynamics of heart rate variability (HRV) indicators.Materials and methods. 102 patients were randomly assigned to 3 groups: 37 patients who received standard opioid anesthesia (control group), 33 women who received the LOA group, and 32 patients who received OFA.Results. Laparoscopic hysterectomy is accompanied by tension of the autonomic nervous system, especially its sympathetic link, which is manifested by an increase in the index of vago-sympathetic interaction at the traumatic stage of the operation. These changes were most significant in patients who received standard and opioid-free anesthesia, which indirectly indicates insufficient stress protection of these types of intraoperative anesthesia.Conclusions. The use of low-opioid anesthesia is accompanied by a greater stabilization of HRV indices, which indicates its sufficient autonomic protection during laparoscopic hysterectomy than standard and opioid-free anesthesia.

scholarly journals A STUDY OF THE EFFECTIVENESS OF DIFFERENT METHODS OF ANESTHESIA IN VICTIMS OF ROAD TRAFFIC ACCIDENTS WITH THORACOABDOMINAL TRAUMA IN PRE-HOSPITAL AND HOSPITAL PERIODS

2021 ◽  
Vol 22 (1) ◽  
pp. 46-52
Author(s):  
A. G. Miroshnichenko ◽  
R. M. Rakhmanov ◽  
М. A. Bolshakova ◽  
A. A. Popov ◽  
E. A. Popova ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Traffic Accidents ◽  
Comparison Group ◽  
Road Traffic ◽  
Main Group ◽  
Road Traffic Accidents ◽  
Analog Scale ◽  
Combined Use

A study was conducted in 149 patients with diagnoses of thoracoabdominal trauma. In order to objectify the severity of the patients’ condition, a visual analog scale was used. To assess the state of the function of the autonomic nervous system in patients of the comparison group and the main group after the therapy, an analysis of heart rate variability was performed during the day. The combined use of dalargin, a narcotic analgesic and a non-steroidal anti-inflammatory drug, provided good analgesia, neurovegetative protection, when examined in the emergency room, the victims of the main group were in contact, which contributed to a more thorough collection of complaints, anamnesis and examination of the patient. 

scholarly journals Indicators of vegetative homeostasis in children with mitral valve prolapse before and after treatment

2019 ◽  
Vol 23 (2) ◽  
pp. 234-237
Author(s):  
A. V. Kuleshov ◽  
Y. A. Medrazhevska
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Mitral Valve ◽  
Mitral Valve Prolapse ◽  
Medical Literature ◽  
The Body ◽  
Control Group ◽  
Healthy Children ◽  
Before And After

For children with mitral valve prolapse (MVP) characterized by disorders of vegetative homeostasis, especially pronounced effect on the body sympathetic link of the autonomic nervous system. In the medical literature, the question of correction of vegetative tone in children with primary MVP is now open. The purpose of the study was to study the parameters of vegetative homeostasis in children with mitral valve prolapse before and after treatment. 66 children with primary and primary MVP stage I and II at the age of 13–17 years were examined. The control group consisted of 23 practically healthy children. The evaluation of vegetative homeostasis was performed using a clinorostatic test and cardiointervalography, followed by an analysis of the parameters and parameters of the heart rate variability spectral analysis. To restore vegetative homeostasis to patients with PMC, an existing treatment regimen with our correction was prescribed. Namely, we added therapies levocarnitine and magnesium. According to the data obtained from the CP, we found that treatment led to the normalization of vegetative maintenance of the organism, mainly in the form of a decrease in the hypersympathicotonic tonic type after treatment, along with the baseline (p<0.05). Consequently, the proposed treatment scheme with the use of levocarnitine and magnesium, positively affects the autonomic system in children with primary MVP, reducing its dysfunction.

scholarly journals Alterations of Autonomic Nervous System Activity in Children with Spina Bifida: A Case-Control Study

2021 ◽  
Author(s):  
Sang Woon Kim ◽  
Israel Franco ◽  
Yong Seung Lee ◽  
Sang Won Han
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Spina Bifida ◽  
Parasympathetic Activity ◽  
Control Group ◽  
Urodynamic Study ◽  
Bladder Filling ◽  
Autonomic Nervous

Abstract We compared heart rate variability parameters of patients with spina bifida with those of a control group during urodynamic study to evaluate the autonomic nervous system dysfunction of spina bifida. Continuous heart rate variability parameters were recorded during 3 successive periods (P0: 2 minutes before the start of filling; P1: start of filling to the first desire to void; P2: P1 to the end of filling or the start of voiding). Children with vesicoureteral reflux who underwent video-urodynamic study were established as a control group. We included 11 patients with spina bifida and 9 controls. At baseline, patients with spina bifida had lower values of RMSSD, pNN50, and HF, while LF/HF ratio was increased (5.04 ± 4.75 vs 0.67 ± 0.42, p = 0.014). During bladder filling, LF/HF values increased in the control group (P0 0.67 ± 0.42 vs P1 0.89 ± 0.34 vs P2 1.21 ± 0.64, p = 0.018) while it was decreased in spina bifida patients (P0 5.04 ± 4.75 vs P1 3.96 ± 4.35 vs P2 3.26 ± 4.03, p < 0.001). HF were significantly increased in spina bifida children during bladder filling (p = 0.002). In time domain, SDNN was increased only in control group during bladder filling. Parasympathetic activity domains were decreased in children with spina bifida at baseline. During the bladder filling phase, parasympathetic activity increased with fixed sympathetic activity in spina bifida group while the control group demonstrated a shifted balance toward sympathetic preponderance at the end of bladder filling. These findings may be related to the pathophysiology of neurogenic bladder in spina bifida.

scholarly journals Correlation between adipocytokine profile and heart rate variability in patients with obesity

2020 ◽  
Vol 37 (3) ◽  
pp. 12-17
Author(s):  
S. G. Shulkina ◽  
E. N. Smirnova ◽  
E. A. Laurent ◽  
N. Yu. Kolomeets ◽  
V. V. Konovalov ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Uric Acid ◽  
Autonomic Nervous System ◽  
Spectral Characteristics ◽  
Heart Rhythm ◽  
Control Group ◽  
Autonomic Nervous ◽  
Group 2

Objective. The high prevalence of obesity in employable population dictates the necessity for preclinical diagnosis of diseases associated with it, including the study of the autonomic regulation of heart rhythm. The objective was to study the correlations between the adipocytokine profile and heart rate variability in patients with obesity. Materials and methods. 300 persons were examined, the average age was 46.2 6.4 years; Group 1 was metabolically unhealthy obesity phenotype (MUHOP) 90 patients; group 2 was obesity without metabolic disorders [Ob(+)MD(-)] (MHOP) 50 persons; the control group consisted of 100 healthy respondents. We studied the following indices: blood serum adipocytokines: leptin, insulin, resistin, adiponectin. Heart rate variability was studied using Poly-Spectrum Rhythm 2012 computer electrocardiograph. Results. In the course of the study, decrease in the total heart rate variability and reactivity of the parasympathetic part of the autonomic nervous system in patients from MUHOP group was found, while there were no differences with the control in the MHOP group. It was established that a decrease in the parasympathetic effect on the regulation of heart rhythm is associated with the presence of abdominal obesity, insulin resistance, and an increase in the level of TG, glucose, resistin, and uric acid. Conclusions. The received relationships between indicators of carbohydrate and lipid metabolism, the level of uric acid and adipocytokines with temporal and spectral characteristics of the autonomic nervous system confirm their contribution to the development of autonomic dysfunction in obese persons.

Nonlinear Analysis of Heart Rate Variability During Qi Therapy (External Qigong)

2005 ◽  
Vol 33 (04) ◽  
pp. 579-588 ◽  
Author(s):  
Myeong Soo Lee ◽  
Young Hoon Rim ◽  
Dong-Myong Jeong ◽  
Mo Kyung Kim ◽  
Min Cheol Joo ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Nervous System ◽  
Autonomic Nervous System ◽  
Nonlinear Analysis ◽  
Control Group ◽  
Placebo Control ◽  
Poincaré Plot ◽  
Cardiac Autonomic Nervous System ◽  
Autonomic Nervous

Heart rate variability (HRV) was compared in 30 subjects receiving external Qi therapy (EQT) or placebo control therapy, in a crossover design experiment. Subjects who received the EQT reported more pleasant and calm emotions than did the placebo group. Qi therapy reduced the heart rate and increased HRV as indicated by a reduced low frequency/high frequency power ratio of HRV. With nonlinear analysis, the Poincaré plot index of HRV and approximate entropy was greater in the EQT group than in the control group. These findings suggest that EQT stabilizes the sympathovagal function and cardiac autonomic nervous system by inducing more positive emotions than the placebo therapy. In conclusion, EQT may act by stabilizing both the autonomic nervous system and the emotional state.

scholarly journals Influence of Tocolytic Therapy with Hexoprenaline on Heart Rate Variability, Lipid Spectrum and Glycemic Level in Obese Pregnant Women

2021 ◽  
Vol 6 (1) ◽  
pp. 7-12
Author(s):  
L. V. Gureeva ◽  
O. M. Chistyakova ◽  
E. K. Paramonova ◽  
O. V. Radkov
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Pregnant Women ◽  
Low Frequency ◽  
Holter Monitoring ◽  
Serum Glucose ◽  
High Density Lipoproteins ◽  
Control Group ◽  
Glycemic Level ◽  
Lipid Spectrum

Background. Obesity is associated with the risk of spontaneous preterm birth. Hexoprenaline is the effective and most widely used tocolytic agent, possessing however a significant number of side effects. The effect of hexoprenaline tocolysis on heart rate variability, lipid spectrum and glycaemia level in obese pregnant women remain unexplored.Aim of the research. To study the effect of tocolytic therapy with hexoprenaline on heart rate variability, lipid spectrum and glycemic level in obese pregnant women.Materials and methods. The study included two groups of pregnant women with threatened preterm labor who received tocolysis with hexoprenaline. One group consisted of 68 obese patients, the other – 72 non-obese pregnant women (control group). Patients underwent Holter monitoring. Fasting serum glucose and lipids spectrum were measured before starting tocolytic therapy and after 24 hours of tocolysis.Results. In obese pregnant women with hexoprenaline infusion, the heart rate, the 24-hours number of supraventricular extrasystoles and ventricular extrasystoles during the day are significantly higher. Frequency domain parameters, very low frequency during the day, low frequency at night and 24-hours high frequency were significantly decreased than in control group. After a day of tocolysis in obese pregnant women, the level of total cholesterol, low density lipoproteins, triglycerides, and glucose significantly increases when compared with the results before therapy. For patients in the control group treated with hexoprenaline, only the concentration of high-density lipoproteins is increased.Conclusion. Obesity in pregnant women receiving hexoprenaline tocolysis is associated with low heart rate variability and an increase in the number of cardiac arrhythmias, as well as lipid disorders and an increase in glucose level.

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