Giving up knowledge is almost never a good idea: an interview with Dr Evan Zahn

2019 ◽  
Vol 29 (12) ◽  
pp. 1419-1425
Author(s):  
Sebastian Góreczny ◽  
Evan M. Zahn
Keyword(s):  
Imaging Techniques ◽  
Three Dimensional ◽  
Interventional Cardiology ◽  
Cardiac Catheterisation ◽  
Natural Order ◽  
Treatment Technique ◽  
Rotational Angiography ◽  
New Device ◽  
Imaging Tool ◽  
Dimensional Reconstruction

The history of congenital interventional cardiology has seen numerous groundbreaking innovations typically related to the introduction of a new device or a novel treatment technique. Similarly, imaging of cardiac defects has changed dramatically over the past decades, although some of the advancements have seemed to omit the catheterisation laboratories. Rotational angiography, one of the imaging techniques for guidance of cardiac catheterisation currently referred to as “advanced”, in fact was described already in 1960s.1 More recently its improved version, including three-dimensional reconstruction (3DRA), became a valuable intra-procedural imaging tool in interventional cardiology and neuroradiology.2 Dr Evan Zahn was one of the pioneers of 3DRA in the field of congenital cardiology, setting an example for many to follow. With his innovative publication and subsequent lecture at 2011 Pediatric and Adult Interventional Cardiac Symposium (PICS-AICS) on “The Emerging Use of 3-Dimensional Rotational Angiography in Congenital Heart Disease” he motivated many to explore benefits of this modality to strive for improved procedural outcomes and reduced patients’ burden of cardiac catheterisation3. I was one of those to take Dr Zahn’s thoughts and implement them into routine workflow.4–6 However, almost a decade after Dr Zahn shared his important work, despite tremendous efforts by teams from Utrecht, (Netherlands) and Columbus (Ohio, United States of America) to popularise 3D imaging in catheterisation laboratory during dedicated meetings, two-dimensional (2D) angiography does not seem to be threatened in many, otherwise-progressive, laboratories. During the recent 30th Japanese Pediatric Interventional Cardiology (JPIC) meeting I had the opportunity to ask Dr Zahn why giving up knowledge is almost never a good idea, what is technology’s natural order of things, and why the technology has to be more than just exciting, pretty, and new.

Three-Dimensional Reconstruction of the Coronary Sinus Using Rotational Angiography

2005 ◽  
Vol 16 (6) ◽  
pp. 675-676 ◽  
Author(s):  
MOUSSA MANSOUR ◽  
VIVEK Y. REDDY ◽  
JAGMEET SINGH ◽  
THEOFANIE MELA ◽  
VOLKER RASCHE ◽  
...  
Keyword(s):  
Coronary Sinus ◽  
Three Dimensional ◽  
Three Dimensional Reconstruction ◽  
Rotational Angiography ◽  
Dimensional Reconstruction

Computational fluid dynamics in a model of the total cavopulmonary connection reconstructed using magnetic resonance images

2005 ◽  
Vol 15 (S3) ◽  
pp. 61-67 ◽  
Author(s):  
Laura Socci ◽  
Francesca Gervaso ◽  
Francesco Migliavacca ◽  
Giancarlo Pennati ◽  
Gabriele Dubini ◽  
...  
Keyword(s):  
Fluid Dynamics ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Magnetic Resonance Images ◽  
Total Cavopulmonary Connection ◽  
Anatomical Structures ◽  
Human Bones ◽  
Dimensional Reconstruction ◽  
Recent Developments ◽  
Cavopulmonary Connection

The recent developments in imaging techniques have created new opportunities to give an accurate description of the three-dimensional morphology of vessels. Such three-dimensional reconstruction of anatomical structures from medical images has achieved importance in several applications, such as the reconstruction of human bones, spine portions, and vascular districts.

scholarly journals Optical imaging and modulation of neurovascular responses

2018 ◽  
Vol 38 (12) ◽  
pp. 2057-2072 ◽  
Author(s):  
Kazuto Masamoto ◽  
Alberto Vazquez
Keyword(s):  
Optical Imaging ◽  
Vascular Function ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Brain Regions ◽  
Transgenic Animal ◽  
Optical Methods ◽  
Vascular Networks ◽  
Temporal Properties ◽  
Dimensional Reconstruction

The cerebral microvasculature consists of pial vascular networks, parenchymal descending arterioles, ascending venules and parenchymal capillaries. This vascular compartmentalization is vital to precisely deliver blood to balance continuously varying neural demands in multiple brain regions. Optical imaging techniques have facilitated the investigation of dynamic spatial and temporal properties of microvascular functions in real time. Their combination with transgenic animal models encoding specific genetic targets have further strengthened the importance of optical methods for neurovascular research by allowing for the modulation and monitoring of neuro vascular function. Image analysis methods with three-dimensional reconstruction are also helping to understand the complexity of microscopic observations. Here, we review the compartmentalized cerebral microvascular responses to global perturbations as well as regional changes in response to neural activity to highlight the differences in vascular action sites. In addition, microvascular responses elicited by optical modulation of different cell-type targets are summarized with emphasis on variable spatiotemporal dynamics of microvascular responses. Finally, long-term changes in microvascular compartmentalization are discussed to help understand potential relationships between CBF disturbances and the development of neurodegenerative diseases and cognitive decline.

scholarly journals Three-Dimensional Reconstruction of the Coronary Sinus With Rotational Angiography

2008 ◽  
Vol 72 (6) ◽  
pp. 1020-1021 ◽  
Author(s):  
Masayoshi Kofune ◽  
Ichiro Watanabe ◽  
Sonoko Ashino ◽  
Yasuo Okumura ◽  
Kazunori Kawauchi ◽  
...  
Keyword(s):  
Coronary Sinus ◽  
Three Dimensional ◽  
Three Dimensional Reconstruction ◽  
Rotational Angiography ◽  
Dimensional Reconstruction

scholarly journals Customized Scaffold Design Based on Natural Peripheral Nerve Fascicle Characteristics for Biofabrication in Tissue Regeneration

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Zhi Yao ◽  
Li-Wei Yan ◽  
Shuai Qiu ◽  
Fu-Lin He ◽  
Fan-Bin Gu ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Tibial Nerve ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Common Peroneal Nerve ◽  
Nerve Graft ◽  
Three Dimensional Reconstruction ◽  
Scaffold Design ◽  
Dimensional Reconstruction ◽  
Nerve Fascicle

Objective. The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human peripheral nerve fascicles. Methods. We used Micro-MRI technique to obtain different nerve fascicles. A full-length 28 cm tibial nerve specimen was obtained and was divided into 14 two-centimetre nerve segments. 3D models of the nerve fascicles were obtained by three-dimensional reconstruction after image segmentation. The central line of the nerve fascicles was fitted, and the aggregation of nerve fascicles was analysed quantitatively. The nerve scaffold was designed by simulating the clinical nerve defect and extracting information from the acquired nerve fascicle data; the scaffold design was displayed by 3D printing to verify the accuracy of the model. Result. The microstructure of the sciatic nerve, tibial nerve, and common peroneal nerve in the nerve fascicles could be obtained by three-dimensional reconstruction. The number of cross fusions of tibial nerve fascicles from proximal end to distal end decreased gradually. By designing the nerve graft in accordance with the microstructure of the nerve fascicles, the 3D printed model demonstrated that the two ends of the nerve defect can be well matched. Conclusion. The microstructure of the nerve fascicles is complicated and changeable, and the spatial position of each nerve fascicle and the long segment of the nerve fascicle aggregation show great changes at different levels. Under the premise of the stability of the existing imaging techniques, a large number of scanning nerve samples can be used to set up a three-dimensional database of the peripheral nerve fascicle microstructure, integrating the gross imaging information, and provide a template for the design of the downstream nerve graft model.

scholarly journals Descriptive anatomy of the largest known specimen of Protoichthyosaurus prostaxalis (Reptilia: Ichthyosauria) including computed tomography and digital reconstruction of a three-dimensional skull

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6112 ◽  
Author(s):  
Dean R. Lomax ◽  
Laura B. Porro ◽  
Nigel R. Larkin
Keyword(s):  
Computed Tomography ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Lower Jurassic ◽  
Science Museum ◽  
Three Dimensional Reconstruction ◽  
Digital Reconstruction ◽  
Reconstruction Methods ◽  
Dimensional Reconstruction ◽  
Marine Reptile

Ichthyosaur fossils are abundant in Lower Jurassic sediments with nine genera found in the UK. In this paper, we describe the partial skeleton of a large ichthyosaur from the Lower Jurassic (lower Sinemurian) of Warwickshire, England, which was conserved and rearticulated to form the centrepiece of a new permanent gallery at the Thinktank, Birmingham Science Museum in 2015. The unusual three-dimensional preservation of the specimen permitted computed tomography (CT) scanning of individual braincase elements as well as the entire reassembled skull. This represents one of the first times that medical imaging and three-dimensional reconstruction methods have been applied to a large skull of a marine reptile. Data from these scans provide new anatomical information, such as the presence of branching vascular canals within the premaxilla and dentary, and an undescribed dorsal (quadrate) wing of the pterygoid hidden within matrix. Scanning also revealed areas of the skull that had been modelled in wood, clay and other materials after the specimen’s initial discovery, highlighting the utility of applying advanced imaging techniques to historical specimens. Additionally, the CT data served as the basis for a new three-dimensional reconstruction of the skull, in which minor damage was repaired and the preserved bones digitally rearticulated. Thus, for the first time a digital reconstruction of the skull and mandible of a large marine reptile skull is available. Museum records show the specimen was originally identified as an example of Ichthyosaurus communis but we identify this specimen as Protoichthyosaurus prostaxalis. The specimen features a skull nearly twice as long as any previously described specimen of P. prostaxalis, representing an individual with an estimated total body length between 3.2 and 4 m.

Live 3D image overlay for arterial duct closure with Amplatzer Duct Occluder II additional size

2015 ◽  
Vol 26 (3) ◽  
pp. 605-608 ◽  
Author(s):  
Sebstian Goreczny ◽  
Gareth J. Morgan ◽  
Pawel Dryzek
Keyword(s):  
Three Dimensional ◽  
Two Dimensional ◽  
3D Image ◽  
Rotational Angiography ◽  
Amplatzer Duct Occluder ◽  
Imaging Tool ◽  
Arterial Duct ◽  
Ductal Closure ◽  
Device Placement ◽  
Image Overlay

AbstractDespite several reports describing echocardiography for the guidance of ductal closure, two-dimensional angiography remains the mainstay imaging tool; three-dimensional rotational angiography has the potential to overcome some of the drawbacks of standard angiography, and reconstructed image overlay provides reliable guidance for device placement. We describe arterial duct closure solely from venous approach guided by live three-dimensional image overlay.

Interest of convex spherical anamorphosis in better understanding of brain AVMs' angioarchitecture

2015 ◽  
Vol 8 (9) ◽  
pp. 959-964 ◽  
Author(s):  
Frédéric Clarençon ◽  
Franck Maizeroi-Eugène ◽  
Flavien Maingreaud ◽  
Damien Bresson ◽  
David Ayoub ◽  
...  
Keyword(s):  
Plane Surface ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Vascular Imaging ◽  
Rotational Angiography ◽  
Imaging Data ◽  
Significant Difference ◽  
Arterial Feeder ◽  
Brain Avms ◽  
Barrel Distortion

IntroductionConvex spherical anamorphosis is a barrel distortion that consists of the application of a plane surface on a convex hemisphere. Applied in vascular imaging of brain arteriovenous malformations (bAVMs), this deformation may help to ‘spread’ the nidus and surrounding vessels (arteries/veins) and thus to differentiate the different components of bAVMs more accurately.MethodsThe imaging data from 15 patients (8 male, 7 female; 14 supratentorial bAVMs, 1 infratentorial) were used to test the algorithm. The algorithm was applied to three-dimensional rotational angiography (3D-RA) volume rendering reconstructions in anteroposterior, lateral and oblique views and compared with regular 3D-RA and DSA. Arterial feeder and draining vein count and quality visualization of the main draining vein and intranidal aneurysms were compared between the three imaging techniques.ResultsAnamorphosis was able to depict more arterial feeders than 3D-RA alone (p=0.027). There was no statistically significant difference between 6 f/s DSA and anamorphosis for arterial feeder count. No difference was observed in draining vein count between the three imaging modalities. Visualization of the precise origin of the main draining vein was considered to be good in 67% of the cases with anamorphosis versus 47% and 33% for 6 f/s DSA and 3D-RA alone, respectively. Intranidal aneurysms were accurately depicted by anamorphosis (2 cases), whereas 6 f/s DSA and 3D-RA showed doubtful images in one and two additional cases, respectively, which were finally confirmed as focal venous ectasias on supraselective injection.ConclusionsAnamorphosis can help to visualize more precisely the main draining vein origin of the bAVM and depict more accurately intranidal aneurysms.

Bilateral, isolated, lateral semicircular canal malformation without hearing loss

2008 ◽  
Vol 122 (8) ◽  
pp. 858-860 ◽  
Author(s):  
I Dallan ◽  
S Berrettini ◽  
E Neri ◽  
A P Casani
Keyword(s):  
Hearing Loss ◽  
Inner Ear ◽  
Semicircular Canal ◽  
Imaging Techniques ◽  
Three Dimensional ◽  
Lateral Semicircular Canal ◽  
Normal Limits ◽  
Dimensional Reconstruction ◽  
Ear Malformations ◽  
Molecular Aspects

AbstractHypothesis:Inner-ear malformations are frequently found in patients with sensorineural hearing loss. However, isolated anomalies of the vestibular part of the inner ear are seldom described, and for this reason their impact on balance is poorly understood.Care report:We present the case of a 38-year-old Caucasian man with recurrent vestibular complaints, with a sensation of linear tilting, but no hearing impairment. Clinical and neuro-otological examinations showed peripheral involvement of the vestibular system, while audiological investigation was within normal limits. High-resolution magnetic resonance imaging of the inner ear, with three-dimensional reconstruction, demonstrated isolated vestibular anomalies involving both the lateral semicircular canal and the utricle.Conclusions:Bearing in mind this case, we speculate that isolated vestibular malformation may not be as rare as previously thought, and should be investigated with the aid of sophisticated imaging techniques. A review of the relative literature, focussing attention on the molecular aspects, is also reported.

Sign in / Sign up

Export Citation Format

Share Document