Health-Related Findings Among Twin Pairs Discordant for Leisure-Time Physical Activity for 32 Years: The TWINACTIVE Study Synopsis

2015 ◽  
Vol 18 (3) ◽  
pp. 266-272 ◽  
Author(s):  
Tuija Leskinen ◽  
Urho M. Kujala
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Adult Life ◽  
Related Factors ◽  
Time Activity ◽  
Regulatory Pathways ◽  
Fat Depots ◽  
Health Related

We are lacking very long-term and controlled intervention studies investigating the effects of habitual physical activity on health-related factors. To address this gap, we performed a natural experiment by identifying same-sex twin pairs in which the co-twins of each pair differed with respect to leisure-time physical-activity habits throughout their adult life. Our criterion for the discordance was that the same co-twin had a higher leisure time-activity volume than that of the other member of the pair at the majority –– if not all –– of the follow-up time points according to reported/interviewed physical-activity data. Overall, we identified and conducted multidimensional health-related measurements (including fitness, body composition, cardiometabolic risk factor levels, bone and arterial status, and exercise motivation) of 16 twin pairs (seven monozygotic (MZ) and nine dizygotic (DZ) pairs, mean age 60 years) who had persistent discordance in leisure-time physical-activity habits over three decades (TWINACTIVE study). In our discordant-pair study design, after adjusting for sequence-level genes, both systemic-level metabolic, and site-specific structural findings differed significantly in the pairwise analysis in MZ pairs only. These findings included intrapair differences in accumulated fat depots and structure of heart, arteries, and bones. In addition, our study revealed intrapair differences in metabolic and regulatory pathways, which may partly explain the mechanistic links between long-term physical activity, phenotypic changes, and decreased risk of cardiometabolic diseases.

scholarly journals Multimorbidity and leisure-time physical activity over the life course: a population-based birth cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Natan Feter ◽  
Jayne S. Leite ◽  
Daniel Umpierre ◽  
Eduardo L. Caputo ◽  
Airton J. Rombaldi
Keyword(s):  
Physical Activity ◽  
Life Course ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Adult Life ◽  
Population Based ◽  
Independent Effect ◽  
Sensitive Period ◽  
Birth Cohort Study ◽  
Saturated Model

Abstract Background We aimed to test which life course model best described the association between leisure-time physical activity (LTPA) and multimorbidity at age 55. We analyzed data from birth to age 55 using the database from the 1958 National Child Development Survey. Methods Multimorbidity was considered as the presence of more than one chronic condition. LTPA was measured through questionnaires from 1965 (age 7) to 2013 (age 55), which were applied in eight different occasions. We compared the fit of a series of nested adjusted logistic regression models (representing either the critical, accumulation or sensitive period models) with a fully saturated model. Data were reported as odds ratio (OR) and 95% confidence interval (CI). Results From an eligible sample of 15,613 cohort members, 9137 were interviewed in the latest sweep (58.5%). Men were more physically active than women at ages 11, 16, and 23 (p < 0.001). LTPA every day in the week was more frequent in women than men in ages 33, 42, and 50 (p < 0.001). The prevalence of multimorbidity at age 55 was 33.0% (n = 2778). The sensitive analysis revealed that LTPA during adolescence (OR: 0.83; 95% CI: 0.70, 0.98) and mid adult life (age 50 and 55; OR: 0.82; 95%CI: 0.69, 0.98) have a stronger effect on the risk for multimorbidity at age 55 considering all other life stages in the model. Also, adolescence showed a critical independent effect on the risk for multimorbidity (OR: 0.82; 95%CI: 0.70, 0.97). No difference was found between those models. Conclusions These data support the notion of a protective physical activity “legacy” at early ages of childhood against multimorbidity at older ages. We highlight the need for LTPA promotion through intervention tailored especially on schooling and older ages in order to reduce the burden of multimorbidity.

scholarly journals Association of Leisure-Time Physical Activity Across the Adult Life Course With All-Cause and Cause-Specific Mortality

2019 ◽  
Vol 2 (3) ◽  
pp. e190355 ◽  
Author(s):  
Pedro F. Saint-Maurice ◽  
Diarmuid Coughlan ◽  
Scott P. Kelly ◽  
Sarah K. Keadle ◽  
Michael B. Cook ◽  
...  
Keyword(s):  
Physical Activity ◽  
Life Course ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Adult Life ◽  
Specific Mortality

scholarly journals Long-Term Leisure Time Physical Activity and Properties of Bone: A Twin Study

2009 ◽  
Vol 24 (8) ◽  
pp. 1427-1433 ◽  
Author(s):  
Hongqiang Ma ◽  
Tuija Leskinen ◽  
Markku Alen ◽  
Sulin Cheng ◽  
Sarianna Sipilä ◽  
...  
Keyword(s):  
Physical Activity ◽  
Twin Study ◽  
Leisure Time ◽  
Leisure Time Physical Activity

Reasons and Barriers for University Students’ Leisure-Time Physical Activity: Moderating Effect of Health Education

2019 ◽  
Vol 126 (6) ◽  
pp. 1084-1100 ◽  
Author(s):  
Saulius Sukys ◽  
Vida J. Cesnaitiene ◽  
Arunas Emeljanovas ◽  
Brigita Mieziene ◽  
Irena Valantine ◽  
...  
Keyword(s):  
Physical Activity ◽  
Health Education ◽  
University Students ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Survey Method ◽  
Physically Active ◽  
Health Related ◽  
Fitness And Health ◽  
The Relationship

This study aimed to investigate the relationship between health education and motives and barriers for university students’ engagement in leisure-time physical activity (PA). The research sample included 709 students (312 females and 397 males) in different years of study, ranging in age between 18-25 years. A questionnaire survey method revealed a significant positive relationship between fitness and health motives and students’ leisure-time PA. External barriers were negative predictors of students’ leisure-time PA, while more health education-related courses per week were positively associated with students’ leisure-time PA. Finally, we found that the number of health education-related courses per week moderated the relationship between fitness and health motives and students’ leisure-time PA. These findings suggest that university students’ fitness and health motives and external barriers to be physically active outweigh other motives and barriers in determining their leisure-time PA. In addition, health education in university studies can effectively increase students’ health-related motivation for PA.

Long Term Leisure Time Physical Activity Has a Positive Effect on Bone Mass Gain in Girls

2009 ◽  
pp. 091123192713014-29 ◽  
Author(s):  
Eszter Völgyi ◽  
Arja Lyytikäinen ◽  
Frances A Tylavsky ◽  
Patrick HF Nicholson ◽  
Harri Suominen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bone Mass ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Mass Gain ◽  
Positive Effect

How Do Different Occupational Factors Influence Total, Occupational, and Leisure-Time Physical Activity?

2015 ◽  
Vol 12 (2) ◽  
pp. 200-207 ◽  
Author(s):  
Corneel Vandelanotte ◽  
Camille Short ◽  
Matthew Rockloff ◽  
Lee Di Millia ◽  
Kevin Ronan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Total Physical Activity ◽  
Activity Levels ◽  
Full Time ◽  
Cross Sectional ◽  
Time Activity ◽  
Physical Activity Levels ◽  
The Impact

Background:A better understanding of how occupational indicators influence physical activity levels will aid the design of workplace interventions.Methods:Cross-sectional data were collected from 1194 participants through a telephone interview in Queensland, Australia. The IPAQ-long was used to measure physical activity. Multiple logistic regression was applied to examine associations.Results:Of participants, 77.9% were employed full-time, 32.3% had professional jobs, 35.7% were engaged in shift work, 39.5% had physically-demanding jobs, and 66.1% had high physical activity levels. Participants with a physicallydemanding job were less likely to have low total (OR = 0.25, 95% CI = 0.17 to 0.38) and occupational (OR = 0.17, 95% CI = 0.12 to 0.25) physical activity. Technical and trade workers were less likely to report low total physical activity (OR = 0.44, 95% CI = 0.20 to 0.97) compared with white-collar workers. Part-time (OR = 1.74, 95% CI = 1.15 to 2.64) and shift workers (OR = 1.86, 95% CI = 1.21 to 2.88) were more likely to report low leisure-time activity.Conclusions:Overall, the impact of different occupational indicators on physical activity was not strong. As expected, the greatest proportion of total physical activity was derived from occupational physical activity. No evidence was found for compensation effects whereby physically-demanding occupations lead to less leisure-time physical activity or vice versa. This study demonstrates that workplaces are important settings to intervene, and that there is scope to increase leisure-time physical activity irrespective of occupational background.

Effects of 32-Year Leisure Time Physical Activity Discordance in Twin Pairs on Health (TWINACTIVE Study): Aims, Design and Results for Physical Fitness

2009 ◽  
Vol 12 (1) ◽  
pp. 108-117 ◽  
Author(s):  
Tuija Leskinen ◽  
Katja Waller ◽  
Sara Mutikainen ◽  
Sari Aaltonen ◽  
Paula H. A. Ronkainen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Physically Active ◽  
Childhood Experiences ◽  
Bone Properties ◽  
Fitness Tests ◽  
Health Related ◽  
And Function

AbstractThe physically active lifestyle is associated with low future morbidity and mortality, but the causality between physical activity and health is not always clear. As some inherited biological characteristics and childhood experiences may cause selection bias in observational studies, we sought to take them into account by identifying 16 twin pairs (7 MZ, 9 DZ, mean age 60 years) discordant for leisure time physical activity habits for thirty years. We conducted detailed health-related examinations among these twin pairs. Our main aims were to study the effects of physical activity and genes on fitness and body composition, with special reference to body fat compartments, metabolic syndrome components and related diseases and risk factor levels, status of arteries, structure and function of the heart, bone properties, and muscle and fat tissue-related mechanisms linked to physical activity and chronic disease development. Our physical activity assessments showed that inactive co-twins were on average 8.8 MET hours/day less active than their active co-twins through out their midlife (2.2 ± 2.3 vs. 11.0 ± 4.1 MET h/day, p < .001). Follow-up fitness tests showed that physically inactive co-twins were less fit than their active co-twins (estimated VO2peak 26.4 ± 4.9 vs. 32.5 ± 5.5 ml/kg/min, p < .001). Similar differences were found in both MZ and DZ pairs. On the basis of earlier epidemiological observations on nonrelated individuals, these physical activity and fitness differences are large enough to cause differences in many mechanisms and risk factors related to the development of chronic diseases and to permit future analyses.

Sign in / Sign up

Export Citation Format

Share Document