scholarly journals Using the Recycled Parts of a Computer DVD Drive for Fabrication of a Low-Cost Arduino-Based Syringe Pump

Author(s):  
Mohammad Sadegh-cheri
Keyword(s):  
Low Cost ◽  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Istvan Grexa ◽  
Akos Diosdi ◽  
Maria Harmati ◽  
Andras Kriston ◽  
Nikita Moshkov ◽  
...  

AbstractRecent statistics report that more than 3.7 million new cases of cancer occur in Europe yearly, and the disease accounts for approximately 20% of all deaths. High-throughput screening of cancer cell cultures has dominated the search for novel, effective anticancer therapies in the past decades. Recently, functional assays with patient-derived ex vivo 3D cell culture have gained importance for drug discovery and precision medicine. We recently evaluated the major advancements and needs for the 3D cell culture screening, and concluded that strictly standardized and robust sample preparation is the most desired development. Here we propose an artificial intelligence-guided low-cost 3D cell culture delivery system. It consists of a light microscope, a micromanipulator, a syringe pump, and a controller computer. The system performs morphology-based feature analysis on spheroids and can select uniform sized or shaped spheroids to transfer them between various sample holders. It can select the samples from standard sample holders, including Petri dishes and microwell plates, and then transfer them to a variety of holders up to 384 well plates. The device performs reliable semi- and fully automated spheroid transfer. This results in highly controlled experimental conditions and eliminates non-trivial side effects of sample variability that is a key aspect towards next-generation precision medicine.


HardwareX ◽  
2018 ◽  
Vol 4 ◽  
pp. e00027 ◽  
Author(s):  
Valentina E. Garcia ◽  
Jamin Liu ◽  
Joseph L. DeRisi
Keyword(s):  
Low Cost ◽  

2021 ◽  
Author(s):  
D. J. Leech ◽  
S. Lightfoot ◽  
D. Huson ◽  
A. Stratakos

AbstractWe propose a design for a simple paste extruder modification that can be used for the selective deposition and patterning of gels and pastes, using a desktop 3D printer as the primary platform. This technology has found use with a variety of materials in seemingly disparate fields, including the printing of ceramics, food and biological materials, each with a variety of material-specific solutions to enhance printability. However, we focus on a syringe-pump driven system that is simple, low-cost, modular, easily assembled and highly modifiable with a low barrier of entry in order to maximise the generalisability and range of printable materials.


2017 ◽  
Vol 866 ◽  
pp. 244-247
Author(s):  
Pattarinee Klumdoung ◽  
Piyapong Pankaew

This research examines the development of a low cost mobile electrospinning system for fabricating nanofiber. The electrospinning system developed in this study consists of a horizontal needle arrangement and a motor which supports the working system that controls the solution flow rate without an external syringe pump. In order to discover the equipment operating conditions for nanofiber fabrication, the distance from the needle to the target was studied. A PVA solution of 8wt% was used and voltage was applied at 13 kV. The needle to target distances were varied from 8-18 cm. At a distance of 10 cm, the SEM images showed that the smallest diameter of the fiber was 119 nm. The average diameter was in the range of 119-240 nm. Concentrations of the 3 different solutions of PVA, PEO and PCL with the variation of voltage at each concentration were studied. The results show the diameter of PVA at 8 wt% and 12%wt are in the range of 127-197 nm and 222-402 nm, respectively. The diameter of PCL solution at a 20 wt% concentration is in the range of 32-60 nm. PEO at 2 wt% and 4wt% was not able to form as a fiber.


An infusion pump is a medical device that delivers fluids such as nutrients into a patient’s body in controlled amount. They are widely used in clinical settings such as hospitals, nursing homes etc. There are many types of infusion pumps including large volume, patient-controlled analgesia and insulin pumps. Some are designed mainly for stationary use at a patient’s bedside, because infusion pumps are frequently used to administer critical fluids, including high-risk medications, pump failures and can have significant implications for patient’s safety. From 2005 to 2009, FDA received approximately 56,000 reports of adverse events associated with the use of infusion pumps, including numerous injuries and deaths. Some of the problems include software problems, alarm errors, inadequate design, broken components, battery failures, spark, and shock. In order to overcome these problems, our team came up with an idea to rectify. Our project is very compact in size when compared to the ordinary syringe pump. It can be lifted with single hand since it is weightless and the components used in our project are reliable, cost efficient and user friendly.


2019 ◽  
Vol 19 (2) ◽  
pp. 75
Author(s):  
Erry Dwi Kurniawan ◽  
Alwin Adam ◽  
Muhammad Ichlasul Salik ◽  
Paulus Lobo Gareso

Micro/nanopatterns with micro deposition techniques have been used in various applications such as flexible electronic devices, biosensing, and biological tissue engineering. For depositing a small size of droplets that can be controlled, structured and patterned precisely is a very important process for microfabrication. In this study, we developed a low cost and simple system for fabricating micro/nanostructure by a selective micro deposition process using a syringe pump. This method is an additive fabrication method where selective droplet materials are released through a needle of the syringe pump. By translating the rotating stepper motor into a linear movement of the lead screw, it will press the plunger of the syringe and give a force to the fluid inside the syringe, hence a droplet can be injected out. The syringe pump system consists of a syringe, the mechanical unit, and the controller unit. A stepper motor, the lead screw, and the mechanical components are used for the mechanical unit. Arduino Uno microcontroller is used as the controller unit and can be programmed by the computer through GUI (Graphical User Interface). The input parameters, such as the push or pull of flow direction, flow rate, the droplet volume, and syringe size dimension can be inputted by the user as their desired value via keypad or the computer. The measurement results show that the syringe pump has characteristics: the maximum average error value of the measured volume is 2.5% and the maximum average error value of the measured flow rate is 14%. The benefits of a syringe pump for micro deposition can overcome photolithography weaknesses, which require an etching and stencil process in the manufacture of semiconductors. Combining two or more syringes into one system with different droplet materials can be used as a promising method for 3D microfabrication in the future.


2017 ◽  
Vol 17 (1) ◽  
Author(s):  
Erica Skerrett ◽  
Edward Kommwa ◽  
Kelley Maynard ◽  
Alexa Juarez ◽  
Ronald Mataya ◽  
...  

Author(s):  
Nikmatul Jannah ◽  
Syaifudin Syaifudin ◽  
Liliek Soetjiatie ◽  
Muhammad Irfan Ali

In the medical world, patient safety is a top priority. The number of workloads and frequency of use in the long term will affect the accuracy and precision of the equipment, therefore calibration is needed, namely the measurement activities to determine the truth of the appointment value of measuring instruments and/or measuring materials based on the standards of the Minister of Health Regulation No. 54/2015. The purpose of this study is to make the design of the Infusion Device Analyzer on flow rate parameters. The main advantage of this study is that the system can display three calibration results in one measurement at the same setting. The results of the calibration will determine the feasibility of an infusion pump or a syringe pump. This study uses the flow rate formula which is applied to the water level system to obtain the calibration results. The infrared photodiode sensor will detect the flow of water in the chamber that comes from the infusion or syringe pump. Furthermore, the sensor output will be processed by the microcontroller and the reading results are displayed on the liquid crystal display. The average measurement at a setting of 10 ml/hour is 9.36 ml/hour, at a setting of 50 ml/hour is 46.64 ml/hour and at a setting of 100 ml/hour is 96.04 ml/hour. Based on available data, this tool has an average error value of 5.69%, where the value exceeds the tolerance limit allowed by ECRI, which is ± 5%.


Sign in / Sign up

Export Citation Format

Share Document