scholarly journals Programmable Syringe Pump for Selective Micro Droplet Deposition

2019 ◽  
Vol 19 (2) ◽  
pp. 75
Author(s):  
Erry Dwi Kurniawan ◽  
Alwin Adam ◽  
Muhammad Ichlasul Salik ◽  
Paulus Lobo Gareso
Keyword(s):  
Flow Rate ◽  
Flow Direction ◽  
Low Cost ◽  
Stepper Motor ◽  
Average Error ◽  
Syringe Pump ◽  
Pump System ◽  
Lead Screw ◽  
Mechanical Unit ◽  
Maximum Average Error

Micro/nanopatterns with micro deposition techniques have been used in various applications such as flexible electronic devices, biosensing, and biological tissue engineering. For depositing a small size of droplets that can be controlled, structured and patterned precisely is a very important process for microfabrication. In this study, we developed a low cost and simple system for fabricating micro/nanostructure by a selective micro deposition process using a syringe pump. This method is an additive fabrication method where selective droplet materials are released through a needle of the syringe pump. By translating the rotating stepper motor into a linear movement of the lead screw, it will press the plunger of the syringe and give a force to the fluid inside the syringe, hence a droplet can be injected out. The syringe pump system consists of a syringe, the mechanical unit, and the controller unit. A stepper motor, the lead screw, and the mechanical components are used for the mechanical unit. Arduino Uno microcontroller is used as the controller unit and can be programmed by the computer through GUI (Graphical User Interface). The input parameters, such as the push or pull of flow direction, flow rate, the droplet volume, and syringe size dimension can be inputted by the user as their desired value via keypad or the computer. The measurement results show that the syringe pump has characteristics: the maximum average error value of the measured volume is 2.5% and the maximum average error value of the measured flow rate is 14%. The benefits of a syringe pump for micro deposition can overcome photolithography weaknesses, which require an etching and stencil process in the manufacture of semiconductors. Combining two or more syringes into one system with different droplet materials can be used as a promising method for 3D microfabrication in the future.

scholarly journals Simple and Low Cost Design of Infusion Device Analyzer Based on Arduino

2020 ◽  
Vol 2 (2) ◽  
pp. 80-86
Author(s):  
Nikmatul Jannah ◽  
Syaifudin Syaifudin ◽  
Liliek Soetjiatie ◽  
Muhammad Irfan Ali
Keyword(s):  
Flow Rate ◽  
Liquid Crystal Display ◽  
Low Cost ◽  
Infusion Pump ◽  
Average Error ◽  
Measuring Instruments ◽  
Syringe Pump ◽  
Infusion Device ◽  
Infrared Photodiode ◽  
Frequency Of Use

In the medical world, patient safety is a top priority. The number of workloads and frequency of use in the long term will affect the accuracy and precision of the equipment, therefore calibration is needed, namely the measurement activities to determine the truth of the appointment value of measuring instruments and/or measuring materials based on the standards of the Minister of Health Regulation No. 54/2015. The purpose of this study is to make the design of the Infusion Device Analyzer on flow rate parameters. The main advantage of this study is that the system can display three calibration results in one measurement at the same setting. The results of the calibration will determine the feasibility of an infusion pump or a syringe pump. This study uses the flow rate formula which is applied to the water level system to obtain the calibration results. The infrared photodiode sensor will detect the flow of water in the chamber that comes from the infusion or syringe pump. Furthermore, the sensor output will be processed by the microcontroller and the reading results are displayed on the liquid crystal display. The average measurement at a setting of 10 ml/hour is 9.36 ml/hour, at a setting of 50 ml/hour is 46.64 ml/hour and at a setting of 100 ml/hour is 96.04 ml/hour. Based on available data, this tool has an average error value of 5.69%, where the value exceeds the tolerance limit allowed by ECRI, which is ± 5%.

Design of a Velocity Control System Using an Inlet Metered Pump

2017 ◽  
Author(s):  
Hasan H. Ali ◽  
Roger C. Fales ◽  
Noah D. Manring
Keyword(s):  
Fluid Flow ◽  
Control System ◽  
High Efficiency ◽  
Flow Direction ◽  
Low Cost ◽  
Hydraulic Cylinder ◽  
Fast Response ◽  
Open Loop ◽  
Velocity Control ◽  
Pump System

This work introduces a new way to control hydraulic cylinder velocity using an inlet metering pump system to control the hydraulic flow entering the cylinder. The inlet metering system consists of a fixed displacement pump and an inlet metering valve that adjusts the hydraulic fluid flow entering the pump as required. The energy losses associated with flow metering in the system are reduced because the pressure drop across the inlet metering valve can be arbitrarily small. The fluid is supplied to the inlet metering valve at a fixed pressure using a charge pump. A velocity control system is designed using the inlet metering system as means to control the fluid flow to a hydraulic cylinder. In addition to the inlet metering system, the velocity control system designed in this work includes a four-way directional valve to set the fluid flow direction according to the desired direction of the hydraulic cylinder velocity. Open-loop and closed-loop proportional and proportional derivative (P and PD) controllers are designed. Designs with the goals of stability and performance of the system are studied so that a precise and smooth velocity control system for the hydraulic cylinder is achieved. In addition to potentially high efficiency of this system, there is potential for other benefits including low cost, fast response, and less complicated dynamics compared to other systems. The results presented in this work show that the inlet metering velocity control system can be designed so that the system is stable, there is zero overshoot and no oscillation.

The Development of Electrospinning Apparatus to Fabricate Nanofiber for Future Material Applications

2017 ◽  
Vol 866 ◽  
pp. 244-247
Author(s):  
Pattarinee Klumdoung ◽  
Piyapong Pankaew
Keyword(s):  
Flow Rate ◽  
Low Cost ◽  
Average Diameter ◽  
Operating Conditions ◽  
Solution Flow Rate ◽  
Syringe Pump ◽  
Sem Images ◽  
Solution Flow

This research examines the development of a low cost mobile electrospinning system for fabricating nanofiber. The electrospinning system developed in this study consists of a horizontal needle arrangement and a motor which supports the working system that controls the solution flow rate without an external syringe pump. In order to discover the equipment operating conditions for nanofiber fabrication, the distance from the needle to the target was studied. A PVA solution of 8wt% was used and voltage was applied at 13 kV. The needle to target distances were varied from 8-18 cm. At a distance of 10 cm, the SEM images showed that the smallest diameter of the fiber was 119 nm. The average diameter was in the range of 119-240 nm. Concentrations of the 3 different solutions of PVA, PEO and PCL with the variation of voltage at each concentration were studied. The results show the diameter of PVA at 8 wt% and 12%wt are in the range of 127-197 nm and 222-402 nm, respectively. The diameter of PCL solution at a 20 wt% concentration is in the range of 32-60 nm. PEO at 2 wt% and 4wt% was not able to form as a fiber.

scholarly journals Design an Infusion Device Analyzer with Flow Rate Parameters using Photodiode Sensor

2021 ◽  
Vol 3 (2) ◽  
pp. 39-44
Author(s):  
Andjar Pudji Pudji ◽  
Anita Miftahul Maghfiroh ◽  
Nuntachai Thongpance
Keyword(s):  
Flow Rate ◽  
Liquid Crystal Display ◽  
Infusion Pump ◽  
Average Error ◽  
Syringe Pump ◽  
Primary Health ◽  
Infusion Device ◽  
Infusion Devices ◽  
Nutrition And Hydration ◽  
Sd Card

Infusion devices are the basis for primary health care, that is to provide medicine, nutrition, and hydration to patients. One of the infusion devices is a syringe pump and an infusion pump. This device is very important to assist the volume and flow that enters the patient's body, especially in situations related to neonatology or cancer treatment. Therefore, a comparison tool is needed to see whether the equipment is used or not. The purpose of this research is to make an infusion device analyzer (IDA) design with a flow rate parameter. The contribution of this research is that the tool can calculate the correct value of the flow rate that comes out of the infusion pump and syringe pump. The water released by the infusion pump or syringe pump will be converted into droplets which are then detected by the sensor. This tool uses an infrared sensor and a photodiode. The results obtained by the sensor will come by Arduino nano and code it to the 16x2 Character Liquid Crystal Display (LCD) and can be stored on an SD Card so that it can be analyzed further. In setting the flow rate for the syringe pump of 100 mL / hour, the error value is 3.9, 50 ml / hour 0.02, 20 mL / hour 0.378, 10 mL / hour 0.048, and 5 mL / hour 0.01. The results show that the average error of the syringe pump performance read by the module is 0.87. The results obtained from this study can be implemented for the calibration of the infusion pump and the syringe pump so that it can be determined whether the device is suitable or not

scholarly journals Design of Two Channel Infusion Pump Analyzer Using Photo Diode Detector

2021 ◽  
Vol 3 (2) ◽  
pp. 65-69
Author(s):  
Syaifudin Syaifudin ◽  
Muhammad Ridha Mak’ruf ◽  
Sari Luthfiyah ◽  
Sumber Sumber
Keyword(s):  
Flow Rate ◽  
Infusion Pump ◽  
Average Error ◽  
Syringe Pump ◽  
Level System ◽  
Infusion Device ◽  
Long Run ◽  
Infrared Photodiode ◽  
Diode Detector ◽  
Infrared Photodiodes

In the medical world, patient safety is a top priority. The large number of workloads and the frequency of using the devices in the long run will affect the accuracy and accuracy of the tool. If the flow rate and volume of the syringe pump or infusion pump given to the patient are not controlled (overdose or the fluid flow rate is too high) it can cause hypertension, heart failure or pulmonary edema. Therefore, it is necessary to have a calibration, which is an application activity to determine the correctness of the designation of the measuring instrument or measuring material. The purpose of this research is to make a two channel infusion device analyzer using a photodiode sensor. The contribution of this research is that the system can display three calibration results in one measurement at the same setting and can calibrate 2 tools simultaneously. The design of the module is in the form of an infrared photodiode sensor for reading the flowrate value. This study uses an infrared photodiode sensor for channels 1 and 2 installed in the chamber. This study uses a flow rate formula that is applied to the water level system to obtain 3 calibration results. Infrared photodiode sensor will detect the presence of water flowing in the chamber from an infusion or syringe pump. Then the sensor output will be processed by STM32 and 3 calibration results will be displayed on the 20x4 LCD. This tool has an average error value on channel 1 of 3.50% and on channel 2 of 3.39%. It can be concluded that the whole system can work well, the placement and distance between the infrared photodiodes also affects the sensor readings

scholarly journals Low-Cost Touchscreen Driven Programmable Dual Syringe Pump for Life Science Applications

2018 ◽  
Author(s):  
Valentina E. Garcia ◽  
Jamin Liu ◽  
Joseph L. DeRisi
Keyword(s):  
Life Science ◽  
Narrow Range ◽  
Low Cost ◽  
Stepper Motor ◽  
Raspberry Pi ◽  
Syringe Pump ◽  
Motor Controller ◽  
Python Scripting ◽  
A Cell ◽  
3D Printed

AbstractSyringe pumps are powerful tools able to automate routine laboratory practices that otherwise consume large amounts of manual labor time. Commercially available syringe pumps are expensive, difficult to customize, and often preset for a narrow range of operations. Here, we show how to build a programmable dual syringe pump (PDSP) that overcomes these limitations. The PDSP is driven by a Raspberry Pi paired with a stepper motor controller to allow maximal customization via Python scripting. The entire setup can be controlled by a touchscreen for use without a keyboard or mouse. Furthermore, the PDSP is structured around 3D printed parts, enabling users to change any component for their specific application. We demonstrate one application of the PDSP by using it to generate whole cell lysates using a cell homogenizer in an automated fashion.Specifications table

scholarly journals SpheroidPicker for automated 3D cell culture manipulation using deep learning

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Istvan Grexa ◽  
Akos Diosdi ◽  
Maria Harmati ◽  
Andras Kriston ◽  
Nikita Moshkov ◽  
...  
Keyword(s):  
Cell Culture ◽  
Precision Medicine ◽  
High Throughput Screening ◽  
Standard Sample ◽  
Ex Vivo ◽  
Low Cost ◽  
3D Cell Culture ◽  
Syringe Pump ◽  
Experimental Conditions ◽  
The Past

AbstractRecent statistics report that more than 3.7 million new cases of cancer occur in Europe yearly, and the disease accounts for approximately 20% of all deaths. High-throughput screening of cancer cell cultures has dominated the search for novel, effective anticancer therapies in the past decades. Recently, functional assays with patient-derived ex vivo 3D cell culture have gained importance for drug discovery and precision medicine. We recently evaluated the major advancements and needs for the 3D cell culture screening, and concluded that strictly standardized and robust sample preparation is the most desired development. Here we propose an artificial intelligence-guided low-cost 3D cell culture delivery system. It consists of a light microscope, a micromanipulator, a syringe pump, and a controller computer. The system performs morphology-based feature analysis on spheroids and can select uniform sized or shaped spheroids to transfer them between various sample holders. It can select the samples from standard sample holders, including Petri dishes and microwell plates, and then transfer them to a variety of holders up to 384 well plates. The device performs reliable semi- and fully automated spheroid transfer. This results in highly controlled experimental conditions and eliminates non-trivial side effects of sample variability that is a key aspect towards next-generation precision medicine.

Pressure Drop Measurements for Air Flow Through Open-Cell Aluminum Foam

2004 ◽  
Author(s):  
Nihad Dukhan ◽  
Angel Alvarez
Keyword(s):  
Reynolds Number ◽  
Pressure Drop ◽  
Flow Rate ◽  
Aluminum Foam ◽  
Flow Direction ◽  
The Other ◽  
Turbulent Regime ◽  
Thick Sample ◽  
Open Cell ◽  
Two Samples

Wind-tunnel pressure drop measurements for airflow through two samples of forty-pore-per-inch commercially available open-cell aluminum foam were undertaken. Each sample’s cross-sectional area perpendicular to the flow direction measured 10.16 cm by 24.13 cm. The thickness in the flow direction was 10.16 cm for one sample and 5.08 cm for the other. The flow rate ranged from 0.016 to 0.101 m3/s for the thick sample and from 0.025 to 0.134 m3/s for the other. The data were all in the fully turbulent regime. The pressure drop for both samples increased with increasing flow rate and followed a quadratic behavior. The permeability and the inertia coefficient showed some scatter with average values of 4.6 × 10−8 m2 and 2.9 × 10−8 m2, and 0.086 and 0.066 for the thick and the thin samples, respectively. The friction factor decayed with the Reynolds number and was weakly dependent on the Reynolds number for Reynolds number greater than 35.

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